Table 5. Histologic Damage as a Function of Anesthetic Group in Experiments 1–3

Values for hippocampal CA1 and CA3 are percentages of dead neurons (mean ± SD). For the caudoputamen and neocortex, crude damage index scores (median ± interquartile range) are given (0 = no damage; 3 = > 60% neurons damaged). n = 20 per group for Experiments 1 and 2, n = 15 per group for Experiment 3.

BCAO = bilateral carotid artery occlusion; hypotension = venous exsanguination as required to maintain MAP at 35 mmHg throughout 10 min of BCAO; MAP = mean arterial pressure; normotension = MAP of 80–110 mmHg.