Table 1. Cytotoxic Activity of Opioids (μm)
All values are expressed as mean ± SE, (n = 4). The cells were treated for 24 h with various concentrations of each compound, and the viable cell number of HL-60 cells and other cells was determined by trypan blue exclusion or MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) method, respectively. The CC50(μm) was then determined from the dose-response curve.
nd = not determined; A549 = human lung carcinoma; MCF7 = human mammary gland tumor; HL-60 = human promyelocytic leukemic cells; HPLF = human periodontal ligament fibroblast; HGF = human gingival fibroblast; HPC = human pulp cells.