Table 3. Comparison of Metabolic Effects of Bupivacaine (5 mm) on Right and Left Ventricles from Hypoxic and Normoxic Rats
Oxygen consumption and ATP synthesis were measured in the presence of 5 mm bupivacaine. Basal, without adenosine diphosphate (ADP), and ADP-stimulated oxygen consumption rates supported by glutamate are expressed in n[scap]m oxygen · min−1· mg dry weight−1. ATP synthesis rate is expressed in nmol ATP · min−1· mg dry weight−1. ATP-to-oxygen ratio (ATP/O) is calculated as the ratio of the rate of ATP synthesis to the rate of the concomitant respiration in the presence of ADP. Data are mean ± SD (n = 10).
*P < 0.05 versus normoxic LV.
†P < 0.05 versus hypoxic RV.
RV = right ventricular free wall; LV = left ventricular free wall.
