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Table 3. Comparison of Exit-site–dependent Pharmacokinetic Parameters when Assuming or Not Peripheral Elimination for Cisatracurium

Data are presented mean ± SD (range).

*P < 0.0001 (pooled data) between the two models (paired t  test).

Vss= volume of distribution at steady state; k10= elimination rate constant for the first compartment; k12= transfer rate constant from the first to the second compartment; k21= transfer rate constant from the second to the first compartment; Clorg= organ clearance.

Table 3. Comparison of Exit-site–dependent Pharmacokinetic Parameters when Assuming or Not Peripheral Elimination for Cisatracurium
Table 3. Comparison of Exit-site–dependent Pharmacokinetic Parameters when Assuming or Not Peripheral Elimination for Cisatracurium
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