Table 2. Two-compartment Model with Elimination from Both Central and Peripheral Compartments: Exit-site–independent Parameters of Cisatracurium
Data are presented as mean ± SD (range).
A = plasma concentration at t0corresponding to the extrapolation from the distribution curve; B = plasma concentration at t0corresponding to the extrapolation from the elimination curve; α= initial distribution rate constant; β= terminal elimination rate constant; V1= volume of distribution in the central compartment; AUC/D = dose-normalized area under the curve; ClT= total clearance.