Table 2. Influence of 100 mg/kg Morphine and Saline on Respiration in μ-Opioid Receptor Knockout (μOR−/−) Mice and Their Wild-type Littermates (μOR+/+)
Values are mean of the animal means ± SD.
* P values. Treatment effects (least significant differences test):† P < 0.02;
‡ P < 0.01;
§ P < 0.001.
ANOVA = analysis of variance; NS = not significant; VT= tidal volume; RR = breathing frequency; V̇= minute ventilation; S = slope of the hypercapnic ventilatory response.
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