A 56-year-old woman is scheduled for an extensive surgical procedure. She weighs 50 kg and her hematocrit prior to surgery is 37%. You determine that an intraoperative hematocrit of 21% would necessitate transfusion of packed red blood cells. What is this patient's MAXIMUM allowable blood loss?

Several formulas exist for estimating perioperative blood loss. These are typically based on estimated blood volume (EBV) and the patient's hemoglobin or hematocrit values both before and after surgery. Some authors have demonstrated a poor correlation between the commonly used formulas, while others have suggested that, while inaccuracies exist, protocol-driven transfusion practices based on these estimates are useful in the perioperative blood management of patients undergoing surgical procedures. Considering the type of surgical procedure and estimating the amount of blood loss that would trigger transfusion for a particular patient may allow the perioperative care team to better plan and prepare for a patient's perioperative...

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