During emergence from a knee arthroscopy procedure using general anesthesia with a laryngeal mask airway, a 25-year-old, otherwise healthy woman develops laryngospasm requiring the administration of succinylcholine. An hour after the end of the case, she is in the recovery area, awake and alert, but requiring nasal cannula oxygen at 3 L/min to maintain an oxygen saturation of 94%. She has a cough productive of frothy sputum. What is the MOST likely etiology of her continued need for supplemental oxygen?

From the clinical scenario presented, this patient most likely has postobstructive pulmonary edema (also known as negative pressure pulmonary edema). Any mechanism that results in a patient making a forceful inspiratory effort against a closed glottis may cause postobstructive pulmonary edema. However, in the perioperative setting, laryngospasm is the most common cause. Young, healthy patients are felt to be at highest risk of developing postobstructive edema due to the...

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