In the February 2018 ASA Monitor, the ACE question on page 42 was erroneously presented as:
Which of the following medications is most likely to prolong the duration of 0?
The correct question, explanation and answer appear below. The full version of the February ACE question is also available online at monitor.pubs.asahq.org/article.aspx?articleid=2670631.
Which of the following medications is most likely to prolong the duration of nondepolarizing neuromuscular blockade?
(A) Cefazolin (B) Ampicillin (C) Erythromycin (D) Gentamicin
The duration of nondepolarizing neuromuscular blockade can be prolonged by many conditions, and several drugs are associated with prolongation of neuromuscular blockade, including antibiotics, volatile anesthetic agents, lidocaine, furosemide, lithium, and magnesium. In contrast, patients receiving phenytoin typically display resistance to non-depolarizing neuromuscular blocking agents.
Antibiotics associated with prolonged duration of neuro-muscular blockade include:
The aminoglycoside category of antibiotics is most commonly associated with prolongation of neuromuscular blockade, although this is of...