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TREK-1 and TREK-2 Knockout Mice Are Not Resistant to Halothane or Isoflurane

Kira A. Spencer, Ph.D., Christian B. Woods, B.S., Hailey M. Worstman, B.A., Simon C. Johnson, Ph.D., Jan-Marino Ramirez, Ph.D., Philip G. Morgan, M.D., Margaret M. Sedensky, M.D.

Anesthesiology. July 2023: 139(1):63–76

https://doi.org/10.1097/ALN.0000000000004577

Published: July 2023

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Articles

Phosphorylated Upstream Frameshift 1–dependent Nonsense-mediated μ-Opioid Receptor mRNA Decay in the Spinal Cord Contributes to the Development of Neuropathic Allodynia–like Behavior in Rats

Ming-Chun Hsieh, Ph.D., Cheng-Yuan Lai, Ph.D., Chou-Ming Yeh, M.D., Ph.D., Po-Sheng Yang, M.D., Ph.D., Jen-Kun Cheng, M.D., Ph.D., Hsueh-Hsiao Wang, Ph.D., Kuan-Hung Lin, Ph.D., Siao-Tong Nie, U.G., Tzer-Bin Lin, Ph.D., Hsien-Yu Peng, Ph.D.

Anesthesiology. June 2023: 138(6):634–655

https://doi.org/10.1097/ALN.0000000000004550

Published: June 2023

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Articles

GABAergic Signaling during Spinal Cord Stimulation Reduces Cardiac Arrhythmias in a Porcine Model

Kimberly Howard-Quijano, M.D., M.S., Yuki Kuwabara, M.D., Tomoki Yamaguchi, M.D., Kenny Roman, Ph.D., Siamak Salavatian, Ph.D., Bradley Taylor, Ph.D., Aman Mahajan, M.D., Ph.D., M.B.A.

Anesthesiology. April 2023: 138(4):372–387

https://doi.org/10.1097/ALN.0000000000004516

Published: April 2023

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Articles

Mouse Model of Spinal Cord Hypoperfusion with Immediate Paralysis Caused by Endovascular Repair of Thoracic Aortic Aneurysm

Hesham Kelani, M.D., Kara Corps, D.V.M., Sarah Mikula, B.A., Lesley C. Fisher, B.S., Mahmoud T. Shalaan, B.Pharm., Sarah Sturgill, M.S., Mark T. Ziolo, Ph.D., Mahmoud Abdel-Rasoul, M.S., M.P.H., D. Michele Basso, Ed.D., P.T., Hamdy Awad, M.D.

Anesthesiology. April 2023: 138(4):403–419

https://doi.org/10.1097/ALN.0000000000004515

Published: April 2023

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Articles

Intubation Biomechanics: Clinical Implications of Computational Modeling of Intervertebral Motion and Spinal Cord Strain during Tracheal Intubation in an Intact Cervical Spine

Benjamin C. Gadomski, Ph.D., Bradley J. Hindman, M.D., Mitchell I. Page, Ph.D., Franklin Dexter, M.D., Ph.D., F.A.S.A., Christian M. Puttlitz, Ph.D.

Anesthesiology. December 2021: 135(6):1055–1065

https://doi.org/10.1097/ALN.0000000000004024

Published: December 2021

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Articles

Mitochondrial Function and Anesthetic Sensitivity in the Mouse Spinal Cord

Christian B. Woods, B.S., Kira A. Spencer, Ph.D., Sangwook Jung, Ph.D., Hailey M. Worstman, B.A., Jan-Marino Ramirez, Ph.D., Philip G. Morgan, M.D., Margaret M. Sedensky, M.D.

Anesthesiology. June 2021: 134(6):901–914

https://doi.org/10.1097/ALN.0000000000003794

Published: June 2021

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Articles

Spinal Anesthesia Reduces Myocardial Ischemia–triggered Ventricular Arrhythmias by Suppressing Spinal Cord Neuronal Network Interactions in Pigs

Yukiko Omura, M.D., Jasmine P. Kipke, B.S., Siamak Salavatian, Ph.D., Andrew Shea Afyouni, B.S., Christian Wooten, B.A., Robert F. Herkenham, M.S.E., Uri Maoz, Ph.D., Elnaz Lashgari, M.S., Erica A. Dale, Ph.D., Kimberly Howard-Quijano, M.D., M.S., Aman Mahajan, M.D., Ph.D.

Anesthesiology. March 2021: 134(3):405–420

https://doi.org/10.1097/ALN.0000000000003662

Published: March 2021

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Articles

Endoplasmic Reticulum Stress Contributes to Nociception via Neuroinflammation in a Murine Bone Cancer Pain Model

Yanting Mao, Ph.D., Chenchen Wang, Ph.D., Xinyu Tian, M.D., Yulin Huang, Ph.D., Ying Zhang, M.D., Hao Wu, M.D., Shuai Yang, Ph.D., Ke Xu, M.D., Yue Liu, Ph.D., Wei Zhang, Ph.D., Xiaoping Gu, M.D., Ph.D., Zhengliang Ma, M.D., Ph.D.

Anesthesiology. February 2020: 132(2):357–372

https://doi.org/10.1097/ALN.0000000000003078

Published: February 2020

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Articles

Cross-talk between Human Spinal Cord μ-opioid Receptor 1Y Isoform and Gastrin-releasing Peptide Receptor Mediates Opioid-induced Scratching Behavior

Xian-Yu Liu, Ph.D., Yehuda Ginosar, M.B.B.S., Joseph Yazdi, M.D., Alexander Hincker, M.D., Zhou-Feng Chen, Ph.D.

Anesthesiology. August 2019: 131(2):381–391

https://doi.org/10.1097/ALN.0000000000002776

Published: August 2019

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Articles

α2δ-1–Bound N -Methyl-d-aspartate Receptors Mediate Morphine-induced Hyperalgesia and Analgesic Tolerance by Potentiating Glutamatergic Input in Rodents

Meichun Deng, Ph.D., Shao-Rui Chen, M.D., Hong Chen, B.S., Hui-Lin Pan, M.D., Ph.D.

Anesthesiology. May 2019: 130(5):804–819

https://doi.org/10.1097/ALN.0000000000002648

Published: May 2019

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Articles

Plasticity and Function of Spinal Oxytocin and Vasopressin Signaling during Recovery from Surgery with Nerve Injury

Amie L. Severino, Ph.D., Rong Chen, Ph.D., Kenichiro Hayashida, D.V.M., Ph.D., Carol A. Aschenbrenner, M.A., Haiguo Sun, Ph.D., Christopher M. Peters, Ph.D., Silvia Gutierrez, Ph.D., Bethany Pan, B.S., James C. Eisenach, Ph.D.

Anesthesiology. September 2018: 129(3):544–556

https://doi.org/10.1097/ALN.0000000000002290

Published: September 2018

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Articles

Neuroinflammation and Central Sensitization in Chronic and Widespread Pain

Ru-Rong Ji, Ph.D., Andrea Nackley, Ph.D., Yul Huh, B.S., M.S., Niccolò Terrando, Ph.D., William Maixner, D.D.S., Ph.D.

Anesthesiology. August 2018: 129(2):343–366

https://doi.org/10.1097/ALN.0000000000002130

Published: August 2018

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Articles

Transcriptional Changes in Dorsal Spinal Cord Persist after Surgical Incision Despite Preemptive Analgesia with Peripheral Resiniferatoxin

Stephen J. Raithel, B.A., Matthew R. Sapio, Ph.D., Danielle M. LaPaglia, B.A., Michael J. Iadarola, Ph.D., Andrew J. Mannes, M.D.

Anesthesiology. March 2018: 128(3):620–635

https://doi.org/10.1097/ALN.0000000000002006

Published: March 2018

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Articles

DNA Hydroxymethylation by Ten-eleven Translocation Methylcytosine Dioxygenase 1 and 3 Regulates Nociceptive Sensitization in a Chronic Inflammatory Pain Model

Zhiqiang Pan, Ph.D., Zhou-Ya Xue, M.D., Guo-Fang Li, M.D., Meng-Lan Sun, M.D., Ming Zhang, M.D., Ling-Yun Hao, M.D., Qian-Qian Tang, M.D., Li-Jiao Zhu, M.D., Jun-Li Cao, M.D., Ph.D.

Anesthesiology. July 2017: 127(1):147–163

https://doi.org/10.1097/ALN.0000000000001632

Published: July 2017

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Articles

Growth Arrest and DNA-damage–inducible Protein 45β-mediated DNA Demethylation of Voltage-dependent T-type Calcium Channel 3.2 Subunit Enhances Neuropathic Allodynia after Nerve Injury in Rats

Cheng-Yuan Lai, B.S., Ming-Chun Hsieh, M.Sc., Yu-Cheng Ho, Ph.D., An-Sheng Lee, Ph.D., Hsueh-Hsiao Wang, Ph.D., Jen-Kun Cheng, M.D., Ph.D., Yat-Pang Chau, Ph.D., Hsien-Yu Peng, Ph.D.

Anesthesiology. June 2017: 126(6):1077–1095

https://doi.org/10.1097/ALN.0000000000001610

Published: June 2017

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Articles

MicroRNA-182-5p Regulates Nerve Injury–induced Nociceptive Hypersensitivity by Targeting Ephrin Type-b Receptor 1

Xuelong Zhou, M.D., Ph.D., Chenjing Zhang, M.D., Ph.D., Congjuan Zhang, R.N., Yunan Peng, M.D., Yin Wang, M.D., Hongjiao Xu, M.D.

Anesthesiology. May 2017: 126(5):967–977

https://doi.org/10.1097/ALN.0000000000001588

Published: May 2017

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Articles

Raman Spectroscopy Differentiates Each Tissue from the Skin to the Spinal Cord: A Novel Method for Epidural Needle Placement?

T. Anthony Anderson, Ph.D., M.D., Jeon Woong Kang, Ph.D., Tatyana Gubin, Ramachandra R. Dasari, Ph.D., Peter T. C. So, Ph.D.

Anesthesiology. October 2016: 125(4):793–804

https://doi.org/10.1097/ALN.0000000000001249

Published: October 2016

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Articles

Fiber-optic Monitoring of Spinal Cord Hemodynamics in Experimental Aortic Occlusion

Angela S. Kogler, M.S., Thomas V. Bilfinger, M.D., Robert M. Galler, M.D., Rickson C. Mesquita, Ph.D., Michael Cutrone, B.S., Steven S. Schenkel, B.E., Arjun G. Yodh, Ph.D., Thomas F. Floyd, M.D.

Anesthesiology. December 2015: 123(6):1362–1373

https://doi.org/10.1097/ALN.0000000000000883

Published: December 2015

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Articles

Activation of Adenosine Monophosphate–activated Protein Kinase Suppresses Neuroinflammation and Ameliorates Bone Cancer Pain: Involvement of Inhibition on Mitogen-activated Protein Kinase

Huayuan Song, M.D., Yuan Han, M.D., Ph.D., Cailong Pan, B.S., Xueting Deng, M.S., Wenling Dai, B.S., Liang Hu, Ph.D., Chunyi Jiang, Ph.D., Yanjing Yang, M.D., Zhixiang Cheng, M.D., Ph.D., Fei Li, Ph.D., Guangqin Zhang, Ph.D., Xuefeng Wu, Ph.D., Wentao Liu, Ph.D.

Anesthesiology. November 2015: 123(5):1170–1185

https://doi.org/10.1097/ALN.0000000000000856

Published: November 2015

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Articles

Up-regulation of Cathepsin G in the Development of Chronic Postsurgical Pain: An Experimental and Clinical Genetic Study

Xiaodong Liu, B.Sc., M.Eng., Ph.D., Yuanyuan Tian, B.Med., M.Med., Ph.D., Zhaoyu Meng, B.Sc., M.Phil., Ph.D., Yan Chen, B.Sc., M.Sc., Ph.D., Idy H. T. Ho, B.Sc., Kwong Wai Choy, B.Sc., M.Sc., Ph.D., Peter Lichtner, Ph.D., Sunny H. Wong, M.B.Ch.B., D.Phil., M.R.C.P., Jun Yu, M.D., Ph.D., Tony Gin, M.D., F.R.C.A., F.A.N.Z.C.A., F.H.K.C.A., William K. K. Wu, M.Phil., Ph.D., F.R.C.Path., Christopher H. K. Cheng, B.Sc., Ph.D., Matthew T. V. Chan, M.B.B.S., Ph.D., F.A.N.Z.C.A., F.H.K.C.A.

Anesthesiology. October 2015: 123(4):838–850

https://doi.org/10.1097/ALN.0000000000000828

Published: October 2015

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NARROW

TREK-1 and TREK-2 Knockout Mice Are Not Resistant to Halothane or Isoflurane

Phosphorylated Upstream Frameshift 1–dependent Nonsense-mediated μ-Opioid Receptor mRNA Decay in the Spinal Cord Contributes to the Development of Neuropathic Allodynia–like Behavior in Rats

GABAergic Signaling during Spinal Cord Stimulation Reduces Cardiac Arrhythmias in a Porcine Model

Mouse Model of Spinal Cord Hypoperfusion with Immediate Paralysis Caused by Endovascular Repair of Thoracic Aortic Aneurysm

Intubation Biomechanics: Clinical Implications of Computational Modeling of Intervertebral Motion and Spinal Cord Strain during Tracheal Intubation in an Intact Cervical Spine

Mitochondrial Function and Anesthetic Sensitivity in the Mouse Spinal Cord

Spinal Anesthesia Reduces Myocardial Ischemia–triggered Ventricular Arrhythmias by Suppressing Spinal Cord Neuronal Network Interactions in Pigs

Endoplasmic Reticulum Stress Contributes to Nociception via Neuroinflammation in a Murine Bone Cancer Pain Model

Cross-talk between Human Spinal Cord μ-opioid Receptor 1Y Isoform and Gastrin-releasing Peptide Receptor Mediates Opioid-induced Scratching Behavior

α2δ-1–Bound N -Methyl-d-aspartate Receptors Mediate Morphine-induced Hyperalgesia and Analgesic Tolerance by Potentiating Glutamatergic Input in Rodents

Plasticity and Function of Spinal Oxytocin and Vasopressin Signaling during Recovery from Surgery with Nerve Injury

Neuroinflammation and Central Sensitization in Chronic and Widespread Pain

Transcriptional Changes in Dorsal Spinal Cord Persist after Surgical Incision Despite Preemptive Analgesia with Peripheral Resiniferatoxin

DNA Hydroxymethylation by Ten-eleven Translocation Methylcytosine Dioxygenase 1 and 3 Regulates Nociceptive Sensitization in a Chronic Inflammatory Pain Model

Growth Arrest and DNA-damage–inducible Protein 45β-mediated DNA Demethylation of Voltage-dependent T-type Calcium Channel 3.2 Subunit Enhances Neuropathic Allodynia after Nerve Injury in Rats

MicroRNA-182-5p Regulates Nerve Injury–induced Nociceptive Hypersensitivity by Targeting Ephrin Type-b Receptor 1

Raman Spectroscopy Differentiates Each Tissue from the Skin to the Spinal Cord: A Novel Method for Epidural Needle Placement?

Fiber-optic Monitoring of Spinal Cord Hemodynamics in Experimental Aortic Occlusion

Activation of Adenosine Monophosphate–activated Protein Kinase Suppresses Neuroinflammation and Ameliorates Bone Cancer Pain: Involvement of Inhibition on Mitogen-activated Protein Kinase

Up-regulation of Cathepsin G in the Development of Chronic Postsurgical Pain: An Experimental and Clinical Genetic Study

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