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Articles

Left Ventricular Hypertrophy Increases Susceptibility to Bupivacaine-induced Cardiotoxicity through Overexpression of Transient Receptor Potential Canonical Channels in Rats

Hideki Hino, M.D., Tadashi Matsuura, M.D., Ph.D., Miyuki Kuno, M.D., Ph.D., Kotaro Hori, M.D., Ph.D., Shogo Tsujikawa, M.D., Ph.D., Takashi Mori, M.D., Ph.D., Kiyonobu Nishikawa, M.D., Ph.D.

Anesthesiology. November 2020: 133(5):1077–1092

DOI: https://doi.org/10.1097/ALN.0000000000003554

Published: November 2020

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Articles

Isoflurane Modulates Hippocampal Cornu Ammonis Pyramidal Neuron Excitability by Inhibition of Both Transient and Persistent Sodium Currents in Mice

Wenling Zhao, M.D., Mingyue Zhang, M.B., Jin Liu, M.D., Peng Liang, M.D., Rurong Wang, M.D., Ph.D., Hugh C. Hemmings, M.D., Ph.D., Cheng Zhou, Ph.D.

Anesthesiology. July 2019: 131(1):94–104

DOI: https://doi.org/10.1097/ALN.0000000000002753

Published: July 2019

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Articles

Neurosteroids Allopregnanolone Sulfate and Pregnanolone Sulfate Have Diverse Effect on the α Subunit of the Neuronal Voltage-gated Sodium Channels Na v 1.2, Na v 1.6, Na v 1.7, and Na v 1.8 Expressed in Xenopus Oocytes

Takafumi Horishita, M.D., Ph.D., Nobuyuki Yanagihara, Ph.D., Susumu Ueno, M.D., Ph.D., Yuka Sudo, Ph.D., Yasuhito Uezono, M.D., Ph.D., Dan Okura, M.D., Tomoko Minami, M.D., Takashi Kawasaki, M.D., Ph.D., Takeyoshi Sata, M.D., Ph.D.

Anesthesiology. September 2014: 121(3):620–631

DOI: https://doi.org/10.1097/ALN.0000000000000296

Published: September 2014

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Articles

Antimetastatic Potential of Amide-linked Local Anesthetics: Inhibition of Lung Adenocarcinoma Cell Migration and Inflammatory Src Signaling Independent of Sodium Channel Blockade

Tobias Piegeler, M.D., E. Gina Votta-Velis, M.D., Ph.D., Guoquan Liu, Ph.D., Aaron T. Place, Ph.D., David E. Schwartz, M.D., Beatrice Beck-Schimmer, M.D., Richard D. Minshall, Ph.D., Alain Borgeat, M.D.

Anesthesiology. September 2012: 117(3):548–559

DOI: https://doi.org/10.1097/ALN.0b013e3182661977

Published: September 2012

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Articles

Widespread Inhibition of Sodium Channel–dependent Glutamate Release from Isolated Nerve Terminals by Isoflurane and Propofol

Ratnakumari Lingamaneni, Ph.D., Martin L. Birch, B.S., Hugh C. Hemmings, M.D., Ph.D.

Anesthesiology. December 2001: 95(6):1460–1466

DOI: https://doi.org/10.1097/00000542-200112000-00027

Published: December 2001

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Articles

Differential Block of Fast and Slow Inactivating Tetrodotoxin-sensitive Sodium Channels by Droperidol in Spinal Dorsal Horn Neurons

Andrea Olschewski, Dr.med., Michael E. Bräu, P.D. Dr.med., Gunter Hempelmann, Prof. Dr.med. Dr.h.c., Werner Vogel, Prof. Dr.rer.nat., Boris V. Safronov, Ph.D.

Anesthesiology. June 2000: 92(6):1667–1676

DOI: https://doi.org/10.1097/00000542-200006000-00026

Published: June 2000

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Articles

Succinylcholine Metabolite Succinic Acid Alters Steady State Activation in Muscle Sodium Channels

Gertrud Haeseler, M.D., Jacqueline Petzold, Hartmut Hecker, M.D., Axel Würz, M.D., Reinhard Dengler, M.D., Siegfried Piepenbrock, M. D, Martin Leuwer, M.D.

Anesthesiology. May 2000: 92(5):1385–1391

DOI: https://doi.org/10.1097/00000542-200005000-00029

Published: May 2000

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Articles

Suppression of Central Nervous System Sodium Channels by Propofol

Benno Rehberg, MD, Daniel S. Duch, PhD

Anesthesiology. August 1999: 91(2):512–520

DOI: https://doi.org/10.1097/00000542-199908000-00026

Published: August 1999

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Articles

Effects of Halothane and Isoflurane on Fast and Slow Inactivation of Human Heart hH1a Sodium Channels

Anna Stadnicka, PhD, Wai-Meng Kwok, PhD, Hali A. Hartmann, PhD, Zeljko J. Bosnjak, PhD

Anesthesiology. June 1999: 90(6):1671–1683.

DOI: https://doi.org/10.1097/00000542-199906000-00024

Published: June 1999

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Articles

ATX II, A Sodium Channel Toxin, Sensitizes Skeletal Muscle to Halothane, Caffeine, and Ryanodine

Jeffrey E. Fletcher, PhD, Pascal J. Adnet, MD, Hugo Reyford, MD, Steven J. Wieland, PhD, Sherri L. Stewart, BS, Henry Rosenberg, MD

Anesthesiology. May 1999: 90(5):1294–1301

DOI: https://doi.org/10.1097/00000542-199905000-00012

Published: May 1999

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Articles

Halothane Decreases Na,K-ATPase, and Na Channel Activity in Alveolar Type II Cells

Serge Molliex, MD, Bertrand Dureuil, MD, Michel Aubier, MD, Gerard Friedlander, MD, PhD, Jean-Marie Desmonts, MD, Christine Clerici, MD, PhD

Anesthesiology. June 1998: 88(6):1606–1613

DOI: https://doi.org/10.1097/00000542-199806000-00025

Published: June 1998

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Articles

Inhibition of Presynaptic Sodium Channels by Halothane

Lingamaneni Ratnakumari, PhD, Hugh C. Hemmings, MD, PhD

Anesthesiology. April 1998: 88(4):1043–1054

DOI: https://doi.org/10.1097/00000542-199804000-00025

Published: April 1998

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Articles

Sensitization of the Cardiac Na Channel to α 1 -Adrenergic Stimulation by Inhalation Anesthetics : Evidence for Distinct Modulatory Pathways

Henry U. Weight, MD, Wai-Meng Kowk, PhD, Georg C. Rehmert, MD, Zeljko J. Bosnjak, PhD

Anesthesiology. January 1998: 88(1):125–133

DOI: https://doi.org/10.1097/00000542-199801000-00020

Published: January 1998

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Articles

Sodium Channel in Human Malignant Hyperthermia

Jeffrey E. Fletcher, PhD, Steven J. Wieland, PhD, Steven M. Karan, MD, Jill Beech, VMD, Henry Rosenberg, MD

Anesthesiology. May 1997: 86(5):1023–1032

DOI: https://doi.org/10.1097/00000542-199705000-00004

Published: May 1997

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Articles

Central Nervous System Sodium Channels Are Significantly Suppressed at Clinical Concentrations of Volatile Anesthetics

Benno Rehberg, MD, Yong-Hong Xiao, MD, Daniel S. Duch, PhD

Anesthesiology. May 1996: 84(5):1223–1233

DOI: https://doi.org/10.1097/00000542-199605000-00025

Published: May 1996

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Articles

Masseter Muscle Rigidity Associated with Glycine 1306 -to- Alanine Mutation in the Adult Muscle Sodium Channel α-Subunit Gene

Gary M. Vita, MD, Antonel Olckers, MSc, Anne E. Jedlicka, BSc, Alfred L. George, MD, Terry Heiman-Patterson, MD, Henry Rosenberg, MD, Jeffrey E. Fletcher, PhD, Roy C. Levitt, MD

Anesthesiology. May 1995: 82(5):1097–1103

DOI: https://doi.org/10.1097/00000542-199505000-00002

Published: May 1995

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Articles

The Membrane Lipid Cholesterol Modulates Anesthetic Actions on a Human Brain Ion Channel

Benno Rehberg, MD, Bernd W. Urban, PhD, Daniel S. Duch, PhD

Anesthesiology. March 1995: 82(3):749–758

DOI: https://doi.org/10.1097/00000542-199503000-00017

Published: March 1995

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Articles

Stereoselective Inhibition of Neuronal Sodium Channels by Local Anesthetics Evidence For Two Sites of Action?

Stanley Lee-Son, M.B., Ging Kuo Wang, Ph.D., Adriane Concus, Elizabeth Crill, Gary Strichartz, Ph.D.

Anesthesiology. August 1992: 77(2):324–335

DOI: https://doi.org/10.1097/00000542-199208000-00016

Published: August 1992

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Articles

A Preferential Inhibition of Impulses in C-fibers of the Rabbit Vagus Nerve by Veratridine, an Activator of Sodium Channels

Markus Schneider, M.D., Sanjay Datta, M.D., Gary Strichartz, Ph.D.

Anesthesiology. February 1991: 74(2):270–280

DOI: https://doi.org/10.1097/00000542-199102000-00013

Published: February 1991

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Articles

A372 EFFECTS OF LIDOCAINE ANALOG QX-314 ON SINGLE CARDIAC SODIUM CHANNELS

Kevin Gingrich, MD, David Yue, MD PhD

Anesthesiology. September 1990: 73(3A):NA

DOI: https://doi.org/10.1097/00000542-199009001-00369

Published: September 1990

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NARROW

Left Ventricular Hypertrophy Increases Susceptibility to Bupivacaine-induced Cardiotoxicity through Overexpression of Transient Receptor Potential Canonical Channels in Rats

Isoflurane Modulates Hippocampal Cornu Ammonis Pyramidal Neuron Excitability by Inhibition of Both Transient and Persistent Sodium Currents in Mice

Neurosteroids Allopregnanolone Sulfate and Pregnanolone Sulfate Have Diverse Effect on the α Subunit of the Neuronal Voltage-gated Sodium Channels Na v 1.2, Na v 1.6, Na v 1.7, and Na v 1.8 Expressed in Xenopus Oocytes

Antimetastatic Potential of Amide-linked Local Anesthetics: Inhibition of Lung Adenocarcinoma Cell Migration and Inflammatory Src Signaling Independent of Sodium Channel Blockade

Widespread Inhibition of Sodium Channel–dependent Glutamate Release from Isolated Nerve Terminals by Isoflurane and Propofol

Differential Block of Fast and Slow Inactivating Tetrodotoxin-sensitive Sodium Channels by Droperidol in Spinal Dorsal Horn Neurons

Succinylcholine Metabolite Succinic Acid Alters Steady State Activation in Muscle Sodium Channels

Suppression of Central Nervous System Sodium Channels by Propofol

Effects of Halothane and Isoflurane on Fast and Slow Inactivation of Human Heart hH1a Sodium Channels

ATX II, A Sodium Channel Toxin, Sensitizes Skeletal Muscle to Halothane, Caffeine, and Ryanodine

Halothane Decreases Na,K-ATPase, and Na Channel Activity in Alveolar Type II Cells

Inhibition of Presynaptic Sodium Channels by Halothane

Sensitization of the Cardiac Na Channel to α 1 -Adrenergic Stimulation by Inhalation Anesthetics : Evidence for Distinct Modulatory Pathways

Sodium Channel in Human Malignant Hyperthermia

Central Nervous System Sodium Channels Are Significantly Suppressed at Clinical Concentrations of Volatile Anesthetics

Masseter Muscle Rigidity Associated with Glycine 1306 -to- Alanine Mutation in the Adult Muscle Sodium Channel α-Subunit Gene

The Membrane Lipid Cholesterol Modulates Anesthetic Actions on a Human Brain Ion Channel

Stereoselective Inhibition of Neuronal Sodium Channels by Local Anesthetics Evidence For Two Sites of Action?

A Preferential Inhibition of Impulses in C-fibers of the Rabbit Vagus Nerve by Veratridine, an Activator of Sodium Channels

A372 EFFECTS OF LIDOCAINE ANALOG QX-314 ON SINGLE CARDIAC SODIUM CHANNELS

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