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Ropivacaine Promotes Axon Regeneration by Regulating Nav1.8-mediated Macrophage Signaling after Sciatic Nerve Injury in Rats

Yongchen Cui, M.D., Xiaofeng Wang, M.D., Yang Xu, M.D., Yue Cao, M.D., Gang Luo, M.D., Zhe Zhao, M.D., Ph.D., Junfeng Zhang, M.D., Ph.D.

Anesthesiology. December 2023: 139(6):782–800

https://doi.org/10.1097/ALN.0000000000004761

Published: December 2023

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Articles

GABAergic Signaling during Spinal Cord Stimulation Reduces Cardiac Arrhythmias in a Porcine Model

Kimberly Howard-Quijano, M.D., M.S., Yuki Kuwabara, M.D., Tomoki Yamaguchi, M.D., Kenny Roman, Ph.D., Siamak Salavatian, Ph.D., Bradley Taylor, Ph.D., Aman Mahajan, M.D., Ph.D., M.B.A.

Anesthesiology. April 2023: 138(4):372–387

https://doi.org/10.1097/ALN.0000000000004516

Published: April 2023

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Articles

Isoflurane Disrupts Postsynaptic Density-95 Protein Interactions Causing Neuronal Synapse Loss and Cognitive Impairment in Juvenile Mice via Canonical NO-mediated Protein Kinase-G Signaling

Swati Agarwal, Ph.D., Michele L. Schaefer, Ph.D., Caroline Krall, B.V.M.&S., M.Sc., Roger A. Johns, M.D., M.H.S., Ph.D.

Anesthesiology. August 2022: 137(2):212–231

https://doi.org/10.1097/ALN.0000000000004264

Published: August 2022

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Articles

Sevoflurane Exerts Protective Effects in Murine Peritonitis-induced Sepsis via Hypoxia-inducible Factor 1α/Adenosine A2B Receptor Signaling

Kristian-Christos Ngamsri, M.D., Friederike Fabian, M.D., Anika Fuhr, M.Sc., Jutta Gamper-Tsigaras, M.Sc., Andreas Straub, M.D., David Fecher, M.Sc., Maria Steinke, Ph.D., Heike Walles, Ph.D., Jörg Reutershan, M.D., Franziska M. Konrad, M.D.

Anesthesiology. July 2021: 135(1):136–150

https://doi.org/10.1097/ALN.0000000000003788

Published: July 2021

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Articles

Shift of µ-opioid Receptor Signaling in the Dorsal Reticular Nucleus Is Implicated in Morphine-induced Hyperalgesia in Male Rats

Ana Rita Costa, M.Sc, Marília Sousa, B.Sc., Steven P. Wilson, Ph.D., Carlos Reguenga, Ph.D., Armando Teixeira-Pinto, Ph.D., Isaura Tavares, Ph.D., Isabel Martins, Ph.D.

Anesthesiology. September 2020: 133(3):628–644

https://doi.org/10.1097/ALN.0000000000003412

Published: September 2020

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Articles

Oral Dimethyl Fumarate Reduces Peripheral Neuropathic Pain in Rodents via NFE2L2 Antioxidant Signaling

Jiahe Li, Ph.D., Jiacheng Ma, Ph.D., Michael J. Lacagnina, Ph.D., Sabina Lorca, B.S., Max A. Odem, Ph.D., Edgar T. Walters, Ph.D., Annemieke Kavelaars, Ph.D., Peter M. Grace, Ph.D.

Anesthesiology. February 2020: 132(2):343–356

https://doi.org/10.1097/ALN.0000000000003077

Published: February 2020

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Articles

Vascular Endothelial Growth Factor A Signaling Promotes Spinal Central Sensitization and Pain-related Behaviors in Female Rats with Bone Cancer

Xue-Ming Hu, M.D., Ph.D., Wei Yang, M.D., Ph.D., Li-Xia Du, Ph.D., Wen-Qiang Cui, M.D., Ph.D., Wen-Li Mi, M.D., Ph.D., Qi-Liang Mao-Ying, Ph.D., Yu-Xia Chu, Ph.D., Yan-Qing Wang, Ph.D.

Anesthesiology. November 2019: 131(5):1125–1147

https://doi.org/10.1097/ALN.0000000000002916

Published: November 2019

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Articles

Exercise Reverses Nociceptive Sensitization, Upregulated Neuropeptide Signaling, Inflammatory Changes, Anxiety, and Memory Impairment in a Mouse Tibia Fracture Model

Xiaoyou Shi, M.D., Tian-zhi Guo, M.D., Wenwu Li, Ph.D., Peyman Sahbaie, M.D., Kenner C. Rice, Ph.D., Agnieszka Sulima, Ph.D., J. David Clark, M.D., Ph.D., Wade S. Kingery, M.D.

Anesthesiology. September 2018: 129(3):557–575

https://doi.org/10.1097/ALN.0000000000002332

Published: September 2018

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Articles

Plasticity and Function of Spinal Oxytocin and Vasopressin Signaling during Recovery from Surgery with Nerve Injury

Amie L. Severino, Ph.D., Rong Chen, Ph.D., Kenichiro Hayashida, D.V.M., Ph.D., Carol A. Aschenbrenner, M.A., Haiguo Sun, Ph.D., Christopher M. Peters, Ph.D., Silvia Gutierrez, Ph.D., Bethany Pan, B.S., James C. Eisenach, Ph.D.

Anesthesiology. September 2018: 129(3):544–556

https://doi.org/10.1097/ALN.0000000000002290

Published: September 2018

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Articles

Sphingosine-1-phosphate Receptor 2 Signaling Promotes Caspase-11–dependent Macrophage Pyroptosis and Worsens Escherichia coli Sepsis Outcome

Fang Song, M.Sc., Jinchao Hou, Ph.D., Zhecong Chen, M.Sc., Baoli Cheng, Ph.D., Ruyi Lei, M.Sc., Ping Cui, M.Sc., Yaqi Sun, M.Sc., Haihong Wang, Ph.D., Xiangming Fang, M.D.

Anesthesiology. August 2018: 129(2):311–320

https://doi.org/10.1097/ALN.0000000000002196

Published: August 2018

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Articles

Mechanical Ventilation Induces Desensitization of Lung Axl Tyrosine Kinase Receptors

Gail Otulakowski, Ph.D., Doreen Engelberts, A.H.T., Martin Post, Ph.D., Claire Masterson, Ph.D., Brian P. Kavanagh, M.B., M.R.C.P.(I), F.R.C.P.(C)

Anesthesiology. July 2018: 129(1):143–153

https://doi.org/10.1097/ALN.0000000000002140

Published: July 2018

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Articles

Endothelin Signaling Contributes to Modulation of Nociception in Early-stage Tongue Cancer in Rats

Akihiko Furukawa, D.D.S., Masamichi Shinoda, D.D.S., Ph.D., Asako Kubo, Ph.D., Kuniya Honda, D.D.S., Ph.D., Ryuta Akasaka, D.D.S., Yoshiyuki Yonehara, M.D., Ph.D., Koichi Iwata, D.D.S., Ph.D.

Anesthesiology. June 2018: 128(6):1207–1219

https://doi.org/10.1097/ALN.0000000000002139

Published: June 2018

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Articles

Buprenorphine Depresses Respiratory Variability in Obese Mice with Altered Leptin Signaling

Chelsea Angel, B.A., Zachary T. Glovak, B.A., Wateen Alami, B.A., Sara Mihalko, B.A., Josh Price, M.S., Yandong Jiang, M.D., Ph.D., Helen A. Baghdoyan, Ph.D., Ralph Lydic, Ph.D.

Anesthesiology. May 2018: 128(5):984–991

https://doi.org/10.1097/ALN.0000000000002073

Published: May 2018

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Articles

Growth Arrest and DNA-damage–inducible Protein 45β-mediated DNA Demethylation of Voltage-dependent T-type Calcium Channel 3.2 Subunit Enhances Neuropathic Allodynia after Nerve Injury in Rats

Cheng-Yuan Lai, B.S., Ming-Chun Hsieh, M.Sc., Yu-Cheng Ho, Ph.D., An-Sheng Lee, Ph.D., Hsueh-Hsiao Wang, Ph.D., Jen-Kun Cheng, M.D., Ph.D., Yat-Pang Chau, Ph.D., Hsien-Yu Peng, Ph.D.

Anesthesiology. June 2017: 126(6):1077–1095

https://doi.org/10.1097/ALN.0000000000001610

Published: June 2017

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Articles

Oral Application of Magnesium-l-Threonate Attenuates Vincristine-induced Allodynia and Hyperalgesia by Normalization of Tumor Necrosis Factor-α/Nuclear Factor-κB Signaling

Ting Xu, B.S., Dai Li, Ph.D., Xin Zhou, B.S., Han-Dong Ouyang, Ph.D., Li-Jun Zhou, Ph.D., Hang Zhou, Ph.D., Hong-Mei Zhang, Ph.D., Xu-Hong Wei, Ph.D., Guosong Liu, Ph.D., Xian-Guo Liu, Ph.D.

Anesthesiology. June 2017: 126(6):1151–1168

https://doi.org/10.1097/ALN.0000000000001601

Published: June 2017

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Articles

Post Something-or-other Syndrome

Stephen M. Picca, M.D.

Anesthesiology. March 2016: 124(3):733–735

https://doi.org/10.1097/ALN.0000000000000947

Published: March 2016

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Articles

Insulin Signaling in Bupivacaine-induced Cardiac Toxicity: Sensitization during Recovery and Potentiation by Lipid Emulsion

Michael R. Fettiplace, M.S., Katarzyna Kowal, B.S., Richard Ripper, C.V.T., Alexandria Young, B.S., Kinga Lis, B.S., Israel Rubinstein, M.D., Marcelo Bonini, Ph.D., Richard Minshall, Ph.D., Guy Weinberg, M.D.

Anesthesiology. February 2016: 124(2):428–442

https://doi.org/10.1097/ALN.0000000000000974

Published: February 2016

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Articles

Patient-specific Immune States before Surgery Are Strong Correlates of Surgical Recovery

Gabriela K. Fragiadakis, B.A., Brice Gaudillière, M.D., Ph.D., Edward A. Ganio, Ph.D., Nima Aghaeepour, Ph.D., Martha Tingle, R.N., Garry P. Nolan, Ph.D., Martin S. Angst, M.D.

Anesthesiology. December 2015: 123(6):1241–1255

https://doi.org/10.1097/ALN.0000000000000887

Published: December 2015

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Articles

Spinal IL-33/ST2 Signaling Contributes to Neuropathic Pain via Neuronal CaMKII–CREB and Astroglial JAK2–STAT3 Cascades in Mice

Shenbin Liu, B.S., Wen-Li Mi, M.D., Ph.D., Qian Li, M.D., Ph.D., Meng-Ting Zhang, M.D., Ping Han, M.D., Ph.D., Shan Hu, M.D., Ph.D., Qi-Liang Mao-Ying, Ph.D., Yan-Qing Wang, Ph.D.

Anesthesiology. November 2015: 123(5):1154–1169

https://doi.org/10.1097/ALN.0000000000000850

Published: November 2015

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Articles

Sphingosine 1-phosphate Receptor 2 Signaling Suppresses Macrophage Phagocytosis and Impairs Host Defense against Sepsis

JinChao Hou, M.Sc., QiXing Chen, Ph.D., Kai Zhang, M.D., BaoLi Cheng, Ph.D., GuoHao Xie, M.D., XiaoLiang Wu, M.D., Cheng Luo, Ph.D., LiMin Chen, M.Sc., Hong Liu, Ph.D., Bing Zhao, Ph.D., KeZhi Dai, Ph.D., XiangMing Fang, M.D.

Anesthesiology. August 2015: 123(2):409–422

https://doi.org/10.1097/ALN.0000000000000725

Published: August 2015

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NARROW

Ropivacaine Promotes Axon Regeneration by Regulating Nav1.8-mediated Macrophage Signaling after Sciatic Nerve Injury in Rats

GABAergic Signaling during Spinal Cord Stimulation Reduces Cardiac Arrhythmias in a Porcine Model

Isoflurane Disrupts Postsynaptic Density-95 Protein Interactions Causing Neuronal Synapse Loss and Cognitive Impairment in Juvenile Mice via Canonical NO-mediated Protein Kinase-G Signaling

Sevoflurane Exerts Protective Effects in Murine Peritonitis-induced Sepsis via Hypoxia-inducible Factor 1α/Adenosine A2B Receptor Signaling

Shift of µ-opioid Receptor Signaling in the Dorsal Reticular Nucleus Is Implicated in Morphine-induced Hyperalgesia in Male Rats

Oral Dimethyl Fumarate Reduces Peripheral Neuropathic Pain in Rodents via NFE2L2 Antioxidant Signaling

Vascular Endothelial Growth Factor A Signaling Promotes Spinal Central Sensitization and Pain-related Behaviors in Female Rats with Bone Cancer

Exercise Reverses Nociceptive Sensitization, Upregulated Neuropeptide Signaling, Inflammatory Changes, Anxiety, and Memory Impairment in a Mouse Tibia Fracture Model

Plasticity and Function of Spinal Oxytocin and Vasopressin Signaling during Recovery from Surgery with Nerve Injury

Sphingosine-1-phosphate Receptor 2 Signaling Promotes Caspase-11–dependent Macrophage Pyroptosis and Worsens Escherichia coli Sepsis Outcome

Mechanical Ventilation Induces Desensitization of Lung Axl Tyrosine Kinase Receptors

Endothelin Signaling Contributes to Modulation of Nociception in Early-stage Tongue Cancer in Rats

Buprenorphine Depresses Respiratory Variability in Obese Mice with Altered Leptin Signaling

Growth Arrest and DNA-damage–inducible Protein 45β-mediated DNA Demethylation of Voltage-dependent T-type Calcium Channel 3.2 Subunit Enhances Neuropathic Allodynia after Nerve Injury in Rats

Oral Application of Magnesium-l-Threonate Attenuates Vincristine-induced Allodynia and Hyperalgesia by Normalization of Tumor Necrosis Factor-α/Nuclear Factor-κB Signaling

Post Something-or-other Syndrome

Insulin Signaling in Bupivacaine-induced Cardiac Toxicity: Sensitization during Recovery and Potentiation by Lipid Emulsion

Patient-specific Immune States before Surgery Are Strong Correlates of Surgical Recovery

Spinal IL-33/ST2 Signaling Contributes to Neuropathic Pain via Neuronal CaMKII–CREB and Astroglial JAK2–STAT3 Cascades in Mice

Sphingosine 1-phosphate Receptor 2 Signaling Suppresses Macrophage Phagocytosis and Impairs Host Defense against Sepsis

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