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Postoperative Delirium after Dexmedetomidine versus Propofol Sedation in Healthy Older Adults Undergoing Orthopedic Lower Limb Surgery with Spinal Anesthesia: A Randomized Controlled Trial

Hyun-Jung Shin, M.D., Ph.D., Sun Woo Nam, M.D., Heeyeon Kim, M.D., Subin Yim, M.D., Sung-Hee Han, M.D., Ph.D., Jung-Won Hwang, M.D., Ph.D., Sang-Hwan Do, M.D., Ph.D., Hyo-Seok Na, M.D., Ph.D.

Anesthesiology. February 2023: 138(2):164–171

DOI: https://doi.org/10.1097/ALN.0000000000004438

Published: February 2023

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Post–cardiac arrest Sedation Promotes Electroencephalographic Slow-wave Activity and Improves Survival in a Mouse Model of Cardiac Arrest

Takamitsu Ikeda, M.D., Ph.D., Edilberto Amorim, M.D., Yusuke Miyazaki, M.D., Ph.D., Risako Kato, Ph.D., Eizo Marutani, M.D., Michael G. Silverman, M.D., M.P.H., Rajeev Malhotra, M.D., M.S., Ken Solt, M.D., Fumito Ichinose, M.D., Ph.D.

Anesthesiology. December 2022: 137(6):716–732

DOI: https://doi.org/10.1097/ALN.0000000000004390

Published: December 2022

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Walk a Tightrope or Burn a Bridge?: Sedation versus General Anesthesia for Intubation of a Pediatric Difficult Airway

Allan F. Simpao, M.D., M.B.I., Clyde T. Matava, M.B.Ch.B., D.A., M.Med., Andrew Davidson, M.B.B.S., M.D., F.A.N.Z.C.A.

Anesthesiology. October 2022: 137(4):384–386

DOI: https://doi.org/10.1097/ALN.0000000000004343

Published: October 2022

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Sedation versus General Anesthesia for Tracheal Intubation in Children with Difficult Airways: A Cohort Study from the Pediatric Difficult Intubation Registry

Luis Sequera-Ramos, M.D., Elizabeth K. Laverriere, M.D., M.P.H., Annery G. Garcia-Marcinkiewicz, M.D., M.S.C.E., Bingqing Zhang, M.P.H., Pete G. Kovatsis, M.D., John E. Fiadjoe, M.D., for the PeDI Collaborative

Anesthesiology. October 2022: 137(4):418–433

DOI: https://doi.org/10.1097/ALN.0000000000004353

Published: October 2022

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γ-Aminobutyric Acid Type A Receptor Subtypes and Circuit Connections in Midazolam-induced Amnesia, Sedation, and Hypnosis

Stuart A. Forman, M.D., Ph.D.

Anesthesiology. June 2022: 136(6):880–882

DOI: https://doi.org/10.1097/ALN.0000000000004234

Published: June 2022

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General Anesthesia versus Sedation, Both with Hemodynamic Control, during Intraarterial Treatment for Stroke: The GASS Randomized Trial

Axelle Maurice, M.D., François Eugène, M.D., Thomas Ronzière, M.D., Jean-Michel Devys, M.D., Guillaume Taylor, M.D., Aurélie Subileau, M.D., Olivier Huet, M.D., Ph.D., Hakim Gherbi, M.D., Marc Laffon, M.D., Ph.D., Maxime Esvan, M.Sc., Bruno Laviolle, M.D., Ph.D., Helene Beloeil, M.D., Ph.D., for the GASS (General Anesthesia versus Sedation for Acute Stroke Treatment) Study Group and the French Society of Anesthesiologists (SFAR) Research Network

Anesthesiology. April 2022: 136(4):567–576

DOI: https://doi.org/10.1097/ALN.0000000000004142

Published: April 2022

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Spinal Anesthesia with Targeted Sedation based on Bispectral Index Values Compared with General Anesthesia with Masked Bispectral Index Values to Reduce Delirium: The SHARP Randomized Controlled Trial

Charles H. Brown, IV, M.D., M.H.S., Charles Edwards, II, M.D., Charles Lin, M.D., Emily Ledford Jones, M.S., R.N., C.N.L., Lisa R. Yanek, M.P.H., Melody Esmaili, C.R.N.A., Yara Gorashi, B.A., Richard Skelton, B.S., M.H.S., Daniel Kaganov, B.A., Ryan Curto, B.A., Noah L. Lessing, B.S., Stephanie Cha, M.D., Elizabeth Colantuoni, Ph.D., Karin Neufeld, M.D., M.P.H., Frederick Sieber, M.D., Clayton L. Dean, M.D., Charles W. Hogue, M.D.

Anesthesiology. December 2021: 135(6):992–1003

DOI: https://doi.org/10.1097/ALN.0000000000004015

Published: December 2021

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Baseline Vulnerabilities May Play a Larger Role than Depth of Anesthesia or Sedation in Postoperative Delirium

Pratik P. Pandharipande, M.D., M.Sc., Elizabeth L. Whitlock, M.D., M.Sc., Christopher G. Hughes, M.D., M.Sc.

Anesthesiology. December 2021: 135(6):940–942

DOI: https://doi.org/10.1097/ALN.0000000000004039

Published: December 2021

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Anesthesia Mechanisms: A Patchwork Quilt rather than a Wet Blanket?

Logan Voss, Ph.D., Jamie W. Sleigh, M.D.

Anesthesiology. October 2021: 135(4):568–569

DOI: https://doi.org/10.1097/ALN.0000000000003879

Published: October 2021

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Reverse Triggering Dyssynchrony 24 h after Initiation of Mechanical Ventilation

Ricard Mellado Artigas, M.D., L. Felipe Damiani, Ph.D., Thomas Piraino, R.P.T., Tai Pham, M.D., Ph.D., Lu Chen, M.D., Michela Rauseo, M.D., Irene Telias, M.D., Ibrahim Soliman, M.D., Detajin Junhasavasdikul, M.D., César Santis, M.D., Orla M. Smith, Ph.D., Ewan Goligher, M.D., Norman Comtois, Ms.C., Christer Sinderby, Ph.D., Leo Heunks, M.D., Laurent Brochard, M.D.

Anesthesiology. May 2021: 134(5):760–769

DOI: https://doi.org/10.1097/ALN.0000000000003726

Published: May 2021

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Modeling the Effect of Excitation on Depth of Anesthesia Monitoring in γ-Aminobutyric Acid Type A Receptor Agonist ABP-700

Beatrijs I. Valk, M.D., Douglas J. Eleveld, Ph.D., Peter Meyer, M.D., Ph.D., Sascha Meier, M.D., Ph.D., Izaak den Daas, Ph.D., Kai van Amsterdam, M.Sc., Jason A. Campagna, M.D., Ph.D., Steven P. Sweeney, B.Sc., Anthony R. Absalom, M.B.Ch.B., F.R.C.A., M.D., Michel M. R. F. Struys, M.D., Ph.D., F.R.C.A.

Anesthesiology. January 2021: 134(1):35–51

DOI: https://doi.org/10.1097/ALN.0000000000003590

Published: January 2021

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Pharmacokinetics and Pharmacodynamics of Remimazolam (CNS 7056) after Continuous Infusion in Healthy Male Volunteers: Part I. Pharmacokinetics and Clinical Pharmacodynamics

Jürgen Schüttler, M.D., Andreas Eisenried, M.D., M.Sc., Marco Lerch, M.D., Jörg Fechner, M.D., Christian Jeleazcov, M.D., M.Sc., Harald Ihmsen, Ph.D.

Anesthesiology. April 2020: 132(4):636–651

DOI: https://doi.org/10.1097/ALN.0000000000003103

Published: April 2020

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Robots Will Perform Anesthesia in the Near Future

Thomas M. Hemmerling, M.D., D.E.A.A.

Anesthesiology. February 2020: 132(2):219–220

DOI: https://doi.org/10.1097/ALN.0000000000003088

Published: February 2020

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Safe Sedation Re-examined: Comparing the Respiratory Effects of Dexmedetomidine and Propofol

Jonathan P. Wanderer, James P. Rathmell

Anesthesiology. November 2019: 131(5):A19

DOI: https://doi.org/10.1097/ALN.0000000000003008

Published: November 2019

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Upper Airway Collapsibility during Dexmedetomidine and Propofol Sedation in Healthy Volunteers: A Nonblinded Randomized Crossover Study

Åse Lodenius, M.D., Ph.D., D.E.S.A., Kathleen J. Maddison, Ph.D., Brad K. Lawther, M.D., Mika Scheinin, M.D., Ph.D., Lars I. Eriksson, M.D., Ph.D., F.R.C.A., Peter R. Eastwood, Ph.D., David R. Hillman, M.B.B.S., Malin Jonsson Fagerlund, M.D., Ph.D., D.E.S.A., Jennifer H. Walsh, M.Sc., Ph.D.

Anesthesiology. November 2019: 131(5):962–973

DOI: https://doi.org/10.1097/ALN.0000000000002883

Published: November 2019

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Prophylactic Haloperidol Effects on Long-term Quality of Life in Critically Ill Patients at High Risk for Delirium: Results of the REDUCE Study

Paul J. T. Rood, R.N., M.Sc., Marieke Zegers, Ph.D., Arjen J. C. Slooter, M.D., Ph.D., Albert Beishuizen, M.D., Ph.D., Koen S. Simons, M.D., Ph.D., Peter H. J. van der Voort, M.D., Ph.D., Meta C. E. van der Woude, M.D., Peter E. Spronk, M.D., Ph.D., Johannes G. van der Hoeven, M.D., Ph.D., Peter Pickkers, M.D., Ph.D., Mark van den Boogaard, R.N., Ph.D.

Anesthesiology. August 2019: 131(2):328–335

DOI: https://doi.org/10.1097/ALN.0000000000002812

Published: August 2019

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Propofol Sedation Alters Perceptual and Cognitive Functions in Healthy Volunteers as Revealed by Functional Magnetic Resonance Imaging

William L. Gross, M.D., Ph.D., Kathryn K. Lauer, M.D., Xiaolin Liu, Ph.D., Christopher J. Roberts, M.D., Ph.D., Suyan Liu, M.D., Ph.D., Suneeta Gollapudy, M.D., Jeffrey R. Binder, M.D., Shi-Jiang Li, Ph.D., Anthony G. Hudetz, D.B.M., Ph.D.

Anesthesiology. August 2019: 131(2):254–265

DOI: https://doi.org/10.1097/ALN.0000000000002669

Published: August 2019

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Articles

Midazolam Sedation Induces Upper Limb Coordination Deficits That Are Reversed by Flumazenil in Patients with Eloquent Area Gliomas

Nan Lin, M.D., Ph.D., Ruquan Han, M.D., Ph.D., Xuan Hui, M.D., Sc.M., Kaiying Zhang, M.D., Adrian W. Gelb, M.B.Ch.B.

Anesthesiology. July 2019: 131(1):36–45

DOI: https://doi.org/10.1097/ALN.0000000000002726

Published: July 2019

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Articles

A Stress Test for the Brain: Sedation-induced Deficits

Jonathan P. Wanderer, James P. Rathmell

Anesthesiology. July 2019: 131(1):A17

DOI: https://doi.org/10.1097/ALN.0000000000002853

Published: July 2019

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Articles

Nasopharyngeal Tube Effects on Breathing during Sedation for Dental Procedures: A Randomized Controlled Trial

Yuuya Kohzuka, D.D.S., Shiroh Isono, M.D., Ph.D., Sayaka Ohara, D.D.S., Kazune Kawabata, D.D.S., Anri Kitamura, D.D.S., Takashi Suzuki, M.D., Ph.D., Fernanda R. Almeida, D.D.S., M.Sc., Ph.D., Yasunori Sato, Ph.D., Takehiko Iijima, D.D.S., Ph.D., D.M.Sc.

Anesthesiology. June 2019: 130(6):946–957

DOI: https://doi.org/10.1097/ALN.0000000000002661

Published: June 2019

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NARROW

Postoperative Delirium after Dexmedetomidine versus Propofol Sedation in Healthy Older Adults Undergoing Orthopedic Lower Limb Surgery with Spinal Anesthesia: A Randomized Controlled Trial

Post–cardiac arrest Sedation Promotes Electroencephalographic Slow-wave Activity and Improves Survival in a Mouse Model of Cardiac Arrest

Walk a Tightrope or Burn a Bridge?: Sedation versus General Anesthesia for Intubation of a Pediatric Difficult Airway

Sedation versus General Anesthesia for Tracheal Intubation in Children with Difficult Airways: A Cohort Study from the Pediatric Difficult Intubation Registry

γ-Aminobutyric Acid Type A Receptor Subtypes and Circuit Connections in Midazolam-induced Amnesia, Sedation, and Hypnosis

General Anesthesia versus Sedation, Both with Hemodynamic Control, during Intraarterial Treatment for Stroke: The GASS Randomized Trial

Spinal Anesthesia with Targeted Sedation based on Bispectral Index Values Compared with General Anesthesia with Masked Bispectral Index Values to Reduce Delirium: The SHARP Randomized Controlled Trial

Baseline Vulnerabilities May Play a Larger Role than Depth of Anesthesia or Sedation in Postoperative Delirium

Anesthesia Mechanisms: A Patchwork Quilt rather than a Wet Blanket?

Reverse Triggering Dyssynchrony 24 h after Initiation of Mechanical Ventilation

Modeling the Effect of Excitation on Depth of Anesthesia Monitoring in γ-Aminobutyric Acid Type A Receptor Agonist ABP-700

Pharmacokinetics and Pharmacodynamics of Remimazolam (CNS 7056) after Continuous Infusion in Healthy Male Volunteers: Part I. Pharmacokinetics and Clinical Pharmacodynamics

Robots Will Perform Anesthesia in the Near Future

Safe Sedation Re-examined: Comparing the Respiratory Effects of Dexmedetomidine and Propofol

Upper Airway Collapsibility during Dexmedetomidine and Propofol Sedation in Healthy Volunteers: A Nonblinded Randomized Crossover Study

Prophylactic Haloperidol Effects on Long-term Quality of Life in Critically Ill Patients at High Risk for Delirium: Results of the REDUCE Study

Propofol Sedation Alters Perceptual and Cognitive Functions in Healthy Volunteers as Revealed by Functional Magnetic Resonance Imaging

Midazolam Sedation Induces Upper Limb Coordination Deficits That Are Reversed by Flumazenil in Patients with Eloquent Area Gliomas

A Stress Test for the Brain: Sedation-induced Deficits

Nasopharyngeal Tube Effects on Breathing during Sedation for Dental Procedures: A Randomized Controlled Trial

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