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Ropivacaine Promotes Axon Regeneration by Regulating Nav1.8-mediated Macrophage Signaling after Sciatic Nerve Injury in Rats

Yongchen Cui, M.D., Xiaofeng Wang, M.D., Yang Xu, M.D., Yue Cao, M.D., Gang Luo, M.D., Zhe Zhao, M.D., Ph.D., Junfeng Zhang, M.D., Ph.D.

Anesthesiology. December 2023: 139(6):782–800

https://doi.org/10.1097/ALN.0000000000004761

Published: December 2023

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Articles

Novel Pulsed Ultrahigh-frequency Spinal Cord Stimulation Inhibits Mechanical Hypersensitivity and Brain Neuronal Activity in Rats after Nerve Injury

Chin-Tsang Yang, Ph.D., Yun Guan, M.D., Ph.D., Chih-Cheng Chen, Ph.D., Wei-Tso Lin, Ph.D., Kuo-Hsiang Lu, M.S., Chung-Ren Lin, M.D., Ph.D., Bai-Chuang Shyu, Ph.D., Yeong-Ray Wen, M.D., Ph.D.

Anesthesiology. November 2023: 139(5):646–663

https://doi.org/10.1097/ALN.0000000000004680

Published: November 2023

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Articles

Phosphorylated Upstream Frameshift 1–dependent Nonsense-mediated μ-Opioid Receptor mRNA Decay in the Spinal Cord Contributes to the Development of Neuropathic Allodynia–like Behavior in Rats

Ming-Chun Hsieh, Ph.D., Cheng-Yuan Lai, Ph.D., Chou-Ming Yeh, M.D., Ph.D., Po-Sheng Yang, M.D., Ph.D., Jen-Kun Cheng, M.D., Ph.D., Hsueh-Hsiao Wang, Ph.D., Kuan-Hung Lin, Ph.D., Siao-Tong Nie, U.G., Tzer-Bin Lin, Ph.D., Hsien-Yu Peng, Ph.D.

Anesthesiology. June 2023: 138(6):634–655

https://doi.org/10.1097/ALN.0000000000004550

Published: June 2023

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Articles

Intergenerational Perioperative Neurocognitive Disorder in Young Adult Male Rats with Traumatic Brain Injury

Ling-Sha Ju, M.S., Jiepei Zhu, M.D., Ph.D., Jason O. Brant, Ph.D., Timothy E. Morey, M.D., Nikolaus Gravenstein, M.D., Christoph N. Seubert, M.D., Ph.D., Terrie Vasilopoulos, Ph.D., Barry Setlow, Ph.D., Anatoly E. Martynyuk, Ph.D.

Anesthesiology. April 2023: 138(4):388–402

https://doi.org/10.1097/ALN.0000000000004496

Published: April 2023

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Articles

Lung Injury Is Induced by Abrupt Increase in Respiratory Rate but Prevented by Recruitment Maneuver in Mild Acute Respiratory Distress Syndrome in Rats

Paulo Henrique Xavier, M.D., Ana Carolina Fernandes Fonseca, M.D., Leonardo Alves Gonçalves, M.D., Giselle Cavalho de Sousa, M.D., Mariana Coelho da Silva, M.D., Raquel Ferreira de Magalhães Sacramento, Ph.D., Cynthia dos Santos Samary, Ph.D., Mayck Medeiros, B.Sc., Fernanda Ferreira Cruz, M.D., Ph.D., Vera Luiza Capelozzi, M.D., Ph.D., Nathane Satanna Felix, M.D., Ph.D., Paolo Pelosi, M.D., John J. Marini, M.D., Patrícia Rieken Macêdo Rocco, M.D., Ph.D., Pedro Leme Silva, Ph.D.

Anesthesiology. April 2023: 138(4):420–435

https://doi.org/10.1097/ALN.0000000000004479

Published: April 2023

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Articles

Excitation of Putative Glutamatergic Neurons in the Rat Parabrachial Nucleus Region Reduces Delta Power during Dexmedetomidine but not Ketamine Anesthesia

Eric D. Melonakos, Ph.D., Morgan J. Siegmann, B.S., Charles Rey, B.S., Christopher O’Brien, B.S., Ksenia K. Nikolaeva, M.S., Ken Solt, M.D., Christa J. Nehs, Ph.D.

Anesthesiology. October 2021: 135(4):633–648

https://doi.org/10.1097/ALN.0000000000003883

Published: October 2021

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Articles

Acid-sensing Ion Channel 3 Overexpression in Incisions Regulated by Nerve Growth Factor Participates in Postoperative Nociception in Rats

Hao Li, M.D., Huiping Li, M.D., Ph.D., Jing Cheng, M.D., Xicheng Liu, M.D., Zhongjun Zhang, M.D., Chaoran Wu, M.D., Ph.D.

Anesthesiology. December 2020: 133(6):1244–1259

https://doi.org/10.1097/ALN.0000000000003576

Published: December 2020

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Articles

Left Ventricular Hypertrophy Increases Susceptibility to Bupivacaine-induced Cardiotoxicity through Overexpression of Transient Receptor Potential Canonical Channels in Rats

Hideki Hino, M.D., Tadashi Matsuura, M.D., Ph.D., Miyuki Kuno, M.D., Ph.D., Kotaro Hori, M.D., Ph.D., Shogo Tsujikawa, M.D., Ph.D., Takashi Mori, M.D., Ph.D., Kiyonobu Nishikawa, M.D., Ph.D.

Anesthesiology. November 2020: 133(5):1077–1092

https://doi.org/10.1097/ALN.0000000000003554

Published: November 2020

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Articles

Androgenic Modulation of the Chloride Transporter NKCC1 Contributes to Age-dependent Isoflurane Neurotoxicity in Male Rats

Gregory A. Chinn, M.D., Ph.D., Jennifer M. Sasaki Russell, Ph.D., Nicole A. Yabut, B.S., Deenu Maharjan, M.D., Jeffrey W. Sall, Ph.D., M.D.

Anesthesiology. October 2020: 133(4):852–866

https://doi.org/10.1097/ALN.0000000000003437

Published: October 2020

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Articles

Shift of µ-opioid Receptor Signaling in the Dorsal Reticular Nucleus Is Implicated in Morphine-induced Hyperalgesia in Male Rats

Ana Rita Costa, M.Sc, Marília Sousa, B.Sc., Steven P. Wilson, Ph.D., Carlos Reguenga, Ph.D., Armando Teixeira-Pinto, Ph.D., Isaura Tavares, Ph.D., Isabel Martins, Ph.D.

Anesthesiology. September 2020: 133(3):628–644

https://doi.org/10.1097/ALN.0000000000003412

Published: September 2020

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Articles

Dorsal Root Ganglion Stimulation Alleviates Pain-related Behaviors in Rats with Nerve Injury and Osteoarthritis

Guoliang Yu, Ph.D., Ian Segel, B.S., Zhiyong Zhang, M.D., Ph.D., Quinn H. Hogan, M.D., Bin Pan, M.D., Ph.D.

Anesthesiology. August 2020: 133(2):408–425

https://doi.org/10.1097/ALN.0000000000003348

Published: August 2020

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Articles

Distinct Function of Estrogen Receptors in the Rodent Anterior Cingulate Cortex in Pain-related Aversion

Kai-Kai Zang, B.S., Xiao Xiao, Ph.D., Li-Qiang Chen, B.S., Yan Yang, Ph.D., Qi-Lai Cao, B.S., Yu-Long Tang, B.S., Su-Su Lv, B.S., Hong Cao, Ph.D., Ling Zhang, Ph.D., Yu-Qiu Zhang, Ph.D.

Anesthesiology. July 2020: 133(1):165–184

https://doi.org/10.1097/ALN.0000000000003324

Published: July 2020

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Articles

Altered Global Brain Signal during Physiologic, Pharmacologic, and Pathologic States of Unconsciousness in Humans and Rats

Sean Tanabe, B.S., Zirui Huang, Ph.D., Jun Zhang, M.D., Ph.D., Yali Chen, M.D., Stuart Fogel, Ph.D., Julien Doyon, Ph.D., Jinsong Wu, M.D., Ph.D., Jianghui Xu, M.D., Jianfeng Zhang, M.S., Pengmin Qin, Ph.D., Xuehai Wu, M.D., Ph.D., Ying Mao, M.D., Ph.D., George A. Mashour, M.D., Ph.D., Anthony G. Hudetz, D.B.M., Ph.D., Georg Northoff, M.D., Ph.D.

Anesthesiology. June 2020: 132(6):1392–1406

https://doi.org/10.1097/ALN.0000000000003197

Published: June 2020

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Articles

Severe Hypoxemia Prevents Spontaneous and Naloxone-induced Breathing Recovery after Fentanyl Overdose in Awake and Sedated Rats

Philippe Haouzi, M.D., Ph.D., Daniel Guck, D.O., Marissa McCann, B.S., Molly Sternick, B.S., Takashi Sonobe, Ph.D., Nicole Tubbs, B.S.

Anesthesiology. May 2020: 132(5):1138–1150

https://doi.org/10.1097/ALN.0000000000003156

Published: May 2020

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Articles

Countering Opioid-induced Respiratory Depression in Male Rats with Nicotinic Acetylcholine Receptor Partial Agonists Varenicline and ABT 594

Jun Ren, Ph.D., Xiuqing Ding, M.Sc., John J. Greer, Ph.D.

Anesthesiology. May 2020: 132(5):1197–1211

https://doi.org/10.1097/ALN.0000000000003128

Published: May 2020

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Articles

Aldosterone Synthase in Peripheral Sensory Neurons Contributes to Mechanical Hypersensitivity during Local Inflammation in Rats

Doaa M. Mohamed, M.Sc., Mohammed Shaqura, Ph.D., Xiongjuan Li, M.D., Mehdi Shakibaei, Ph.D., Antje Beyer, M.D., Sascha Treskatsch, M.D., Michael Schäfer, M.D., Ph.D., Shaaban A. Mousa, Ph.D.

Anesthesiology. April 2020: 132(4):867–880

https://doi.org/10.1097/ALN.0000000000003127

Published: April 2020

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Articles

Supraspinal Opioid Circuits Differentially Modulate Spinal Neuronal Responses in Neuropathic Rats

Anthony H. Dickenson, Ph.D., Edita Navratilova, Ph.D., Ryan Patel, Ph.D., Frank Porreca, Ph.D., Kirsty Bannister, Ph.D.

Anesthesiology. April 2020: 132(4):881–894

https://doi.org/10.1097/ALN.0000000000003120

Published: April 2020

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Articles

Reduced Sensitivity to Anesthetic Agents upon Lesioning the Mesopontine Tegmental Anesthesia Area in Rats Depends on Anesthetic Type

Anne Minert, Ph.D., Mark Baron, M.Sc., Marshall Devor, Ph.D.

Anesthesiology. March 2020: 132(3):535–550

https://doi.org/10.1097/ALN.0000000000003087

Published: March 2020

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Articles

Static and Dynamic Transpulmonary Driving Pressures Affect Lung and Diaphragm Injury during Pressure-controlled versus Pressure-support Ventilation in Experimental Mild Lung Injury in Rats

Eliete F. Pinto, M.Sc., Raquel S. Santos, Ph.D., Mariana A. Antunes, Ph.D., Ligia A. Maia, Ph.D., Gisele A. Padilha, Ph.D., Joana de A. Machado, M.S., Anna C. F. Carvalho, M.S., Marcos V. S. Fernandes, M.S., Vera L. Capelozzi, M.D., Ph.D., Marcelo Gama de Abreu, M.D., Ph.D., Paolo Pelosi, M.D., F.E.R.S., Patricia R. M. Rocco, M.D., Ph.D., Pedro L. Silva, Ph.D.

Anesthesiology. February 2020: 132(2):307–320

https://doi.org/10.1097/ALN.0000000000003060

Published: February 2020

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Articles

Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Systemic Sepsis in Part by Enhancing Peritoneal Macrophage Bacterial Killing via Heme Oxygenase-1 Induction in Rats

Mirjana Jerkic, M.D., Ph.D., Stéphane Gagnon, M.Sc., Razieh Rabani, B.Sc., Ph.D., Taylor Ward-Able, B.Sc., Claire Masterson, M.Sc., Ph.D., Gail Otulakowski, B.Sc., Ph.D., Gerard F. Curley, M.B., Ph.D., F.C.A.I., John Marshall, M.D., F.R.C.S.C., F.A.C.S., F.C.A.H.S., Brian P. Kavanagh, M.D., John G. Laffey, M.D., M.A., F.C.A.I.

Anesthesiology. January 2020: 132(1):140–154

https://doi.org/10.1097/ALN.0000000000003018

Published: January 2020

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NARROW

Ropivacaine Promotes Axon Regeneration by Regulating Nav1.8-mediated Macrophage Signaling after Sciatic Nerve Injury in Rats

Novel Pulsed Ultrahigh-frequency Spinal Cord Stimulation Inhibits Mechanical Hypersensitivity and Brain Neuronal Activity in Rats after Nerve Injury

Phosphorylated Upstream Frameshift 1–dependent Nonsense-mediated μ-Opioid Receptor mRNA Decay in the Spinal Cord Contributes to the Development of Neuropathic Allodynia–like Behavior in Rats

Intergenerational Perioperative Neurocognitive Disorder in Young Adult Male Rats with Traumatic Brain Injury

Lung Injury Is Induced by Abrupt Increase in Respiratory Rate but Prevented by Recruitment Maneuver in Mild Acute Respiratory Distress Syndrome in Rats

Excitation of Putative Glutamatergic Neurons in the Rat Parabrachial Nucleus Region Reduces Delta Power during Dexmedetomidine but not Ketamine Anesthesia

Acid-sensing Ion Channel 3 Overexpression in Incisions Regulated by Nerve Growth Factor Participates in Postoperative Nociception in Rats

Left Ventricular Hypertrophy Increases Susceptibility to Bupivacaine-induced Cardiotoxicity through Overexpression of Transient Receptor Potential Canonical Channels in Rats

Androgenic Modulation of the Chloride Transporter NKCC1 Contributes to Age-dependent Isoflurane Neurotoxicity in Male Rats

Shift of µ-opioid Receptor Signaling in the Dorsal Reticular Nucleus Is Implicated in Morphine-induced Hyperalgesia in Male Rats

Dorsal Root Ganglion Stimulation Alleviates Pain-related Behaviors in Rats with Nerve Injury and Osteoarthritis

Distinct Function of Estrogen Receptors in the Rodent Anterior Cingulate Cortex in Pain-related Aversion

Altered Global Brain Signal during Physiologic, Pharmacologic, and Pathologic States of Unconsciousness in Humans and Rats

Severe Hypoxemia Prevents Spontaneous and Naloxone-induced Breathing Recovery after Fentanyl Overdose in Awake and Sedated Rats

Countering Opioid-induced Respiratory Depression in Male Rats with Nicotinic Acetylcholine Receptor Partial Agonists Varenicline and ABT 594

Aldosterone Synthase in Peripheral Sensory Neurons Contributes to Mechanical Hypersensitivity during Local Inflammation in Rats

Supraspinal Opioid Circuits Differentially Modulate Spinal Neuronal Responses in Neuropathic Rats

Reduced Sensitivity to Anesthetic Agents upon Lesioning the Mesopontine Tegmental Anesthesia Area in Rats Depends on Anesthetic Type

Static and Dynamic Transpulmonary Driving Pressures Affect Lung and Diaphragm Injury during Pressure-controlled versus Pressure-support Ventilation in Experimental Mild Lung Injury in Rats

Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Systemic Sepsis in Part by Enhancing Peritoneal Macrophage Bacterial Killing via Heme Oxygenase-1 Induction in Rats

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