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Postoperative Delirium after Dexmedetomidine versus Propofol Sedation in Healthy Older Adults Undergoing Orthopedic Lower Limb Surgery with Spinal Anesthesia: A Randomized Controlled Trial

CME Article This article has a Visual Abstract
Hyun-Jung Shin, M.D., Ph.D., Sun Woo Nam, M.D., Heeyeon Kim, M.D., Subin Yim, M.D., Sung-Hee Han, M.D., Ph.D., Jung-Won Hwang, M.D., Ph.D., Sang-Hwan Do, M.D., Ph.D., Hyo-Seok Na, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. February 2023: 138(2):164–171
DOI: https://doi.org/10.1097/ALN.0000000000004438
Published: February 2023
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Spinal Anesthesia with Targeted Sedation based on Bispectral Index Values Compared with General Anesthesia with Masked Bispectral Index Values to Reduce Delirium: The SHARP Randomized Controlled Trial

This article has a Visual Abstract This article has an Audio Podcast
Charles H. Brown, IV, M.D., M.H.S., Charles Edwards, II, M.D., Charles Lin, M.D., Emily Ledford Jones, M.S., R.N., C.N.L., Lisa R. Yanek, M.P.H., Melody Esmaili, C.R.N.A., Yara Gorashi, B.A., Richard Skelton, B.S., M.H.S., Daniel Kaganov, B.A., Ryan Curto, B.A., Noah L. Lessing, B.S., Stephanie Cha, M.D., Elizabeth Colantuoni, Ph.D., Karin Neufeld, M.D., M.P.H., Frederick Sieber, M.D., Clayton L. Dean, M.D., Charles W. Hogue, M.D.
Publication: Anesthesiology
Anesthesiology. December 2021: 135(6):992–1003
DOI: https://doi.org/10.1097/ALN.0000000000004015
Published: December 2021
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Baseline Vulnerabilities May Play a Larger Role than Depth of Anesthesia or Sedation in Postoperative Delirium

This article has an Audio Podcast
Pratik P. Pandharipande, M.D., M.Sc., Elizabeth L. Whitlock, M.D., M.Sc., Christopher G. Hughes, M.D., M.Sc.
Publication: Anesthesiology
Anesthesiology. December 2021: 135(6):940–942
DOI: https://doi.org/10.1097/ALN.0000000000004039
Published: December 2021
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Sleep, Pain, and Cognition: Modifiable Targets for Optimal Perioperative Brain Health

CME Article
Brian P. O’Gara, M.D., M.P.H., Lei Gao, M.D., M.B.B.S., Edward R. Marcantonio, M.D., Balachundhar Subramaniam, M.D., M.P.H., F.A.S.A.
Publication: Anesthesiology
Anesthesiology. December 2021: 135(6):1132–1152
DOI: https://doi.org/10.1097/ALN.0000000000004046
Published: December 2021
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The Cognitive Neuraxis: Epidurals and Postoperative Delirium

Phillip E. Vlisides, M.D., George A. Mashour, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. August 2021: 135(2):197–199
DOI: https://doi.org/10.1097/ALN.0000000000003824
Published: August 2021
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Brief Preoperative Screening for Frailty and Cognitive Impairment Predicts Delirium after Spine Surgery

Maria J. Susano, M.D., Rachel H. Grasfield, B.A., Matthew Friese, M.D., Ph.D., Bernard Rosner, Ph.D., Gregory Crosby, M.D., Angela M. Bader, M.D., James D. Kang, M.D., Timothy R. Smith, M.D., Ph.D., Yi Lu, M.D., Ph.D., F.A.A.N.S., Michael W. Groff, M.D., John H. Chi, M.D., M.P.H., Francine Grodstein, Ph.D., Deborah J. Culley, M.D.
Publication: Anesthesiology
Anesthesiology. December 2020: 133(6):1184–1191
DOI: https://doi.org/10.1097/ALN.0000000000003523
Published: December 2020
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Electroencephalogram Burst-suppression during Cardiopulmonary Bypass in Elderly Patients Mediates Postoperative Delirium

Juan C. Pedemonte, M.D., George S. Plummer, M.D., Shubham Chamadia, Ph.D., Joseph J. Locascio, Ph.D., Eunice Hahm, B.S., Breanna Ethridge, B.A., Jacob Gitlin, B.S., Reine Ibala, B.S., Jennifer Mekonnen, B.S., Katia M. Colon, B.S., M. Brandon Westover, M.D., Ph.D., David A. D’Alessandro, M.D., George Tolis, M.D., Timothy Houle, Ph.D., Kenneth T. Shelton, M.D., Jason Qu, M.D., Oluwaseun Akeju, M.D., M.M.S.C.I.
Publication: Anesthesiology
Anesthesiology. August 2020: 133(2):280–292
DOI: https://doi.org/10.1097/ALN.0000000000003328
Published: August 2020
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Postoperative Delirium: A Minefield of Markers and Mediators

Jamie W. Sleigh, M.D., Amy Gaskell, F.A.N.Z.C.A.
Publication: Anesthesiology
Anesthesiology. August 2020: 133(2):255–257
DOI: https://doi.org/10.1097/ALN.0000000000003383
Published: August 2020
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Association between Use of Angiotensin-converting Enzyme Inhibitors or Angiotensin Receptor Blockers and Postoperative Delirium

Ehab Farag, M.D., F.R.C.A., F.A.S.A., Chen Liang, M.S., Edward J. Mascha, Ph.D., Maged Y. Argalious, M.D., M.Sc., M.B.A., M.Ed., F.A.S.E., F.A.S.A., Jacob Ezell, M.D., Kamal Maheshwari, M.D., M.P.H., Wael Ali Sakr Esa, M.D., Ph.D., M.B.A., Christopher A. Troianos, M.D., F.A.S.E., F.A.S.A., Daniel I. Sessler, M.D.
Publication: Anesthesiology
Anesthesiology. July 2020: 133(1):119–132
DOI: https://doi.org/10.1097/ALN.0000000000003329
Published: July 2020
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Preoperative Cognitive Abnormality, Intraoperative Electroencephalogram Suppression, and Postoperative Delirium: A Mediation Analysis

Bradley A. Fritz, M.D., Christopher R. King, M.D., Ph.D., Arbi Ben Abdallah, Ph.D., Nan Lin, Ph.D., Angela M. Mickle, M.S., Thaddeus P. Budelier, M.D., M.S.F., Jordan Oberhaus, B.S., Daniel Park, B.S., Hannah R. Maybrier, B.S., Troy S. Wildes, M.D., Michael S. Avidan, M.B.B.Ch., for the ENGAGES Research Group*
Publication: Anesthesiology
Anesthesiology. June 2020: 132(6):1458–1468
DOI: https://doi.org/10.1097/ALN.0000000000003181
Published: June 2020
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Intraoperative Oxidative Damage and Delirium after Cardiac Surgery

Marcos G. Lopez, M.D., M.S., Christopher G. Hughes, M.D., M.S., Anthony DeMatteo, B.S., Jason B. O’Neal, M.D., J. Brennan McNeil, B.S., Matthew S. Shotwell, Ph.D., Jennifer Morse, M.S., Michael R. Petracek, M.D., Ashish S. Shah, M.D., Nancy J. Brown, M.D., Frederic T. Billings, IV, M.D., M.Sc.
Publication: Anesthesiology
Anesthesiology. March 2020: 132(3):551–561
DOI: https://doi.org/10.1097/ALN.0000000000003016
Published: March 2020
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Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and Divergence

Lori A. Daiello, Pharm.D., Sc.M., Annie M. Racine, Ph.D., Ray Yun Gou, Ph.D., Edward R. Marcantonio, M.D., Zhongcong Xie, M.D., Ph.D., Lisa J. Kunze, M.D., Kamen V. Vlassakov, M.D., Sharon K. Inouye, M.D., Richard N. Jones, Sc.D., for the SAGES Study Group
Publication: Anesthesiology
Anesthesiology. September 2019: 131(3):477–491
DOI: https://doi.org/10.1097/ALN.0000000000002729
Published: September 2019
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The Devil Is in the Details: Comparison of Postoperative Delirium and Neurocognitive Dysfunction

Jeffrey N. Browndyke, Ph.D., Michael Devinney, M.D., Ph.D., Joseph P. Mathew, M.D., M.H.Sc., M.B.A.
Publication: Anesthesiology
Anesthesiology. September 2019: 131(3):456–458
DOI: https://doi.org/10.1097/ALN.0000000000002823
Published: September 2019
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Postoperative Delirium Is Associated with Long-term Decline in Activities of Daily Living

Zhongyong Shi, M.D., Xinchun Mei, M.D., Cheng Li, M.D., Ph.D., Yupeng Chen, M.D., Hailin Zheng, M.D., Yujie Wu, M.D., Hui Zheng, Ph.D., Liang Liu, M.D., Ph.D., Edward R. Marcantonio, M.D., S.M., Zhongcong Xie, M.D., Ph.D., Yuan Shen, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. September 2019: 131(3):492–500
DOI: https://doi.org/10.1097/ALN.0000000000002849
Published: September 2019
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Neurocognitive Function after Cardiac Surgery: From Phenotypes to Mechanisms

Miles Berger, M.D., Ph.D., Niccolò Terrando, Ph.D., S. Kendall Smith, M.D., Ph.D., Jeffrey N. Browndyke, Ph.D., Mark F. Newman, M.D., Joseph P. Mathew, M.D., M.H.Sc., M.B.A.
Publication: Anesthesiology
Anesthesiology. October 2018: 129(4):829–851
DOI: https://doi.org/10.1097/ALN.0000000000002194
Published: October 2018
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Postoperative Delirium and Postoperative Cognitive Dysfunction: Two Sides of the Same Coin?

Michael J. Devinney, M.D., Ph.D., Joseph P. Mathew, M.D., M.H.Sc., M.B.A., Miles Berger, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. September 2018: 129(3):389–391
DOI: https://doi.org/10.1097/ALN.0000000000002338
Published: September 2018
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Processed Electroencephalogram Monitoring and Postoperative Delirium: A Systematic Review and Meta-analysis

Kristen K. MacKenzie, M.D., Angelitta M. Britt-Spells, Ph.D., Laura P. Sands, Ph.D., Jacqueline M. Leung, M.D., M.P.H.
Publication: Anesthesiology
Anesthesiology. September 2018: 129(3):417–427
DOI: https://doi.org/10.1097/ALN.0000000000002323
Published: September 2018
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Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial

Jacqueline M. Leung, M.D., M.P.H., Laura P. Sands, Ph.D., Ningning Chen, Ph.D., Christopher Ames, M.D., Sigurd Berven, M.D., Kevin Bozic, M.D., Shane Burch, M.D., Dean Chou, M.D., Kenneth Covinsky, M.D., Vedat Deviren, M.D., Sakura Kinjo, M.D., Joel H. Kramer, Psy.D., Michael Ries, M.D., Bobby Tay, M.D., Thomas Vail, M.D., Philip Weinstein, M.D., the Perioperative Medicine Research Group
Publication: Anesthesiology
Anesthesiology. October 2017: 127(4):633–644
DOI: https://doi.org/10.1097/ALN.0000000000001804
Published: October 2017
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A Systematic Review and Meta-analysis Examining the Impact of Incident Postoperative Delirium on Mortality

Gavin M. Hamilton, M.D., M.Sc., Kathleen Wheeler, M.D., B.Sc., Joseph Di Michele, B.H.Sc., Manoj M. Lalu, M.D., Ph.D., Daniel I. McIsaac, M.D., M.P.H.
Publication: Anesthesiology
Anesthesiology. July 2017: 127(1):78–88
DOI: https://doi.org/10.1097/ALN.0000000000001660
Published: July 2017
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Postoperative Delirium: Disconnecting the Network?

George A. Mashour, M.D., Ph.D., Michael S. Avidan, M.B.B.Ch.
Publication: Anesthesiology
Anesthesiology. August 2014: 121(2):214–216
DOI: https://doi.org/10.1097/ALN.0000000000000330
Published: August 2014
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