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Articles

Lidocaine Intraoperative Infusion Pharmacokinetics during Partial Hepatectomy for Living Liver Donation

This article has a Visual Abstract
Cara E. Crouch, M.D., Barbara J. Wilkey, M.D., Adrian Hendrickse, B.M., F.R.C.A., Alexander M. Kaizer, Ph.D., Björn Schniedewind, B.S., Uwe Christians, M.D., Ph.D., Thomas K. Henthorn, M.D., Ana Fernandez-Bustamante, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. January 2023: 138(1):71–81
https://doi.org/10.1097/ALN.0000000000004422
Published: January 2023
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Perioperative Neurofilament Light Plasma Concentrations and Cognition before and after Cardiac Surgery: A Prospective Nested Cohort Study

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Charles H. Brown, IV, M.D., M.H.S., Alexandria Lewis, B.A., Julia Probert, M.D., Michelle Parish, B.S., Jing Tian, M.S., Kaushik Mandal, M.D., Allen Everett, M.D., Elizabeth Colantuoni, Ph.D., Vidyulata Kamath, Ph.D., Charles Hogue, M.D., Abhay Moghekar, M.D.
Publication: Anesthesiology
Anesthesiology. September 2022: 137(3):303–314
https://doi.org/10.1097/ALN.0000000000004327
Published: September 2022
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Dexmedetomidine Clearance Decreases with Increasing Drug Exposure: Implications for Current Dosing Regimens and Target-controlled Infusion Models Assuming Linear Pharmacokinetics

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Ricardo Alvarez-Jimenez, M.D., Ph.D., Maud A. S. Weerink, M.D., Laura N. Hannivoort, M.D., Ph.D., Hong Su, Pharm.D., Michel M. R. F. Struys, M.D., Ph.D., F.R.C.A., Stephan A. Loer, M.D., Ph.D., Pieter J. Colin, Pharm.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. February 2022: 136(2):279–292
https://doi.org/10.1097/ALN.0000000000004049
Published: February 2022
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A Pharmacokinetic and Pharmacodynamic Study of Oral Dexmedetomidine

Shubham Chamadia, Ph.D., Juan C. Pedemonte, M.D., Lauren E. Hobbs, M.A., Hao Deng, M.D., M.P.H., Sarah Nguyen, B.S., Luis I. Cortinez, M.D., Oluwaseun Akeju, M.D., M.M.Sc
Publication: Anesthesiology
Anesthesiology. December 2020: 133(6):1223–1233
https://doi.org/10.1097/ALN.0000000000003568
Published: December 2020
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Intraoperative Oxidative Damage and Delirium after Cardiac Surgery

Marcos G. Lopez, M.D., M.S., Christopher G. Hughes, M.D., M.S., Anthony DeMatteo, B.S., Jason B. O’Neal, M.D., J. Brennan McNeil, B.S., Matthew S. Shotwell, Ph.D., Jennifer Morse, M.S., Michael R. Petracek, M.D., Ashish S. Shah, M.D., Nancy J. Brown, M.D., Frederic T. Billings, IV, M.D., M.Sc.
Publication: Anesthesiology
Anesthesiology. March 2020: 132(3):551–561
https://doi.org/10.1097/ALN.0000000000003016
Published: March 2020
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Influence of Cardiac Output on the Pharmacokinetics of Sufentanil in Anesthetized Pigs

Torsten Birkholz, M.D., Christian Leuthold, M.D., Joachim Schmidt, M.D., Harald Ihmsen, Ph.D., Jürgen Schüttler, M.D., Christian Jeleazcov, M.D., M.Sc.
Publication: Anesthesiology
Anesthesiology. May 2018: 128(5):912–920
https://doi.org/10.1097/ALN.0000000000002160
Published: May 2018
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Pharmacokinetic Properties of a Sufentanil Sublingual Tablet Intended to Treat Acute Pain

Dennis M. Fisher, M.D., Peter Chang, Ph.D., D. Russell Wada, Ph.D., Albert Dahan, M.D., Ph.D., Pamela P. Palmer, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. May 2018: 128(5):943–952
https://doi.org/10.1097/ALN.0000000000002145
Published: May 2018
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Respiratory Effects of the Nociceptin/Orphanin FQ Peptide and Opioid Receptor Agonist, Cebranopadol, in Healthy Human Volunteers

Albert Dahan, M.D., Ph.D., Merel Boom, M.D., Ph.D., Elise Sarton, M.D., Ph.D., Justin Hay, Ph.D., Geert Jan Groeneveld, M.D., Ph.D., Meike Neukirchen, Ph.D., John Bothmer, Ph.D., Leon Aarts, M.D., Ph.D., Erik Olofsen, M.Sc.
Publication: Anesthesiology
Anesthesiology. April 2017: 126(4):697–707
https://doi.org/10.1097/ALN.0000000000001529
Published: April 2017
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Methadone Pharmacogenetics: CYP2B6 Polymorphisms Determine Plasma Concentrations, Clearance, and Metabolism

Evan D. Kharasch, M.D., Ph.D., Karen J. Regina, M.S., Jane Blood, R.N., Christina Friedel, B.S.
Publication: Anesthesiology
Anesthesiology. November 2015: 123(5):1142–1153
https://doi.org/10.1097/ALN.0000000000000867
Published: November 2015
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Lack of Indinavir Effects on Methadone Disposition Despite Inhibition of Hepatic and Intestinal Cytochrome P4503A (CYP3A)

Evan D. Kharasch, M.D., Ph.D., Pamela Sheffels Bedynek, B.S., Christine Hoffer, B.A., Alysa Walker, B.S., Dale Whittington, B.S.
Publication: Anesthesiology
Anesthesiology. February 2012: 116(2):432–447
https://doi.org/10.1097/ALN.0b013e3182423478
Published: February 2012
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Performance of Anesthetic Depth Indexes in Rabbits under Propofol Anesthesia: Prediction Probabilities and Concentration-effect Relations

Aura Silva, M.Sc., Sónia Campos, M.Sc., Joaquim Monteiro, Ph.D., Carlos Venâncio, M.Sc., Bertinho Costa, Ph.D., Paula Guedes de Pinho, Ph.D., Luis Antunes, Ph.D.
Publication: Anesthesiology
Anesthesiology. August 2011: 115(2):303–314
https://doi.org/10.1097/ALN.0b013e318222ac02
Published: August 2011
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An Evaluation of Using Population Pharmacokinetic Models to Estimate Pharmacodynamic Parameters for Propofol and Bispectral Index in Children

Marc J. Coppens, M.D., Douglas J. Eleveld, Ph.D., Johannes H. Proost, Pharm.D., Ph.D., Luc A. M. Marks, D.D.S., Ph.D., Jan F. P. Van Bocxlaer, Pharm.D., Ph.D., Hugo Vereecke, M.D., Ph.D., Anthony R. Absalom, M.D., Michel M. R. F. Struys, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. July 2011: 115(1):83–93
https://doi.org/10.1097/ALN.0b013e31821a8d80
Published: July 2011
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Effect of Rifampicin on S-ketamine and S-norketamine Plasma Concentrations in Healthy Volunteers after Intravenous S-ketamine Administration

Ingeborg Noppers, M.D., Erik Olofsen, M.Sc., Marieke Niesters, M.D., M.Sc., Leon Aarts, M.D., Ph.D., René Mooren, B.Sc., Albert Dahan, M.D., Ph.D., Evan Kharasch, M.D., Ph.D., Elise Sarton, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. June 2011: 114(6):1435–1445
https://doi.org/10.1097/ALN.0b013e318218a881
Published: June 2011
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Efficacy of Tranexamic Acid in Pediatric Craniosynostosis Surgery: A Double-blind, Placebo-controlled Trial

Susan M. Goobie, M.D., F.R.C.P.C., Petra M. Meier, M.D., Luis M. Pereira, Ph.D., Francis X. McGowan, M.D., Randy P. Prescilla, M.D., Laurie A. Scharp, B.Sc., Gary F. Rogers, M.D., Mark R. Proctor, M.D., John G. Meara, M.D., Sulpicio G. Soriano, M.D., David Zurakowski, Ph.D., Navil F. Sethna, M.D.
Publication: Anesthesiology
Anesthesiology. April 2011: 114(4):862–871
https://doi.org/10.1097/ALN.0b013e318210fd8f
Published: April 2011
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Placental Transfer and Fetal Metabolic Effects of Phenylephrine and Ephedrine during Spinal Anesthesia for Cesarean Delivery

Warwick D. Ngan Kee, M.B.Ch.B., M.D., F.A.N.Z.C.A., F.H.K.A.M., Kim S. Khaw, M.B.B.S., F.R.C.A., F.H.K.A.M., Perpetua E. Tan, B.Sc., M.Phil., Floria F. Ng, R.N., B.A.Sc., Manoj K. Karmakar, M.B.B.S., F.R.C.A., F.H.K.A.M.
Publication: Anesthesiology
Anesthesiology. September 2009: 111(3):506–512
https://doi.org/10.1097/ALN.0b013e3181b160a3
Published: September 2009
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Rifampin Greatly Reduces the Plasma Concentrations of Intravenous and Oral Oxycodone

Tuija H. Nieminen, M.D., Nora M. Hagelberg, M.D., Ph.D., Teijo I. Saari, M.D., Ph.D., Antti Pertovaara, M.D., Ph.D., Mikko Neuvonen, M.Sc., Kari Laine, M.D., Ph.D., Pertti J. Neuvonen, M.D., Ph.D., Klaus T. Olkkola, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. June 2009: 110(6):1371–1378
https://doi.org/10.1097/ALN.0b013e31819faa54
Published: June 2009
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Sympathetic Nervous System: Evaluation and Importance for Clinical General Anesthesia

Martin Neukirchen, M.D., Peter Kienbaum, M.D., David S. Warner, M.D., Mark A. Warner, M.D.
Publication: Anesthesiology
Anesthesiology. December 2008: 109(6):1113–1131
https://doi.org/10.1097/ALN.0b013e31818e435c
Published: December 2008
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Reversal of Neuromusclar Blockade and Simultaneous Increase in Plasma Rocuronium Concentration after the Intravenous Infusion of the Novel Reversal Agent Org 25970

Ola Epemolu, Ph.D., Anton Bom, M.D., Ph.D., Frank Hope, B.Sc., Rona Mason, H.N.Cert.
Publication: Anesthesiology
Anesthesiology. September 2003: 99(3):632–637
https://doi.org/10.1097/00000542-200309000-00018
Published: September 2003
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Fetal Plasma Concentrations after Intraamniotic Sufentanil in Chronically Instrumented Pregnant Sheep

Danja Strümper, M.D., Marcel E. Durieux, M.D., Ph.D., Wiebke Gogarten, M.D., Hugo Van Aken, M.D., Ph.D., Kristian Hartleb, Marco A. E. Marcus, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. June 2003: 98(6):1400–1406
https://doi.org/10.1097/00000542-200306000-00015
Published: June 2003
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Simultaneous Assessment of Drug Interactions with Low- and High-Extraction Opioids: Application to Parecoxib Effects on the Pharmacokinetics and Pharmacodynamics of Fentanyl and Alfentanil

Andra E. Ibrahim, M.D., Jennifer Feldman, B.A., Aziz Karim, Ph.D., Evan D. Kharasch, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. April 2003: 98(4):853–861
https://doi.org/10.1097/00000542-200304000-00011
Published: April 2003
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