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Articles

Association of Genetic Variants with Postsurgical Pain: A Systematic Review and Meta-analyses

Stephan G. Frangakis, M.D., Ph.D., Mark MacEachern, M.L.I.S., T. Adam Akbar, M.D., Christian Bolton, M.D., Victor Lin, D.O., Ph.D., Albert V. Smith, Ph.D., Chad M. Brummett, M.D., Mark C. Bicket, M.D., Ph.D.

Anesthesiology. December 2023: 139(6):827–839

https://doi.org/10.1097/ALN.0000000000004677

Published: December 2023

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Articles

Brainstem Modulation of Nociception by Periaqueductal Gray Neurons Expressing the μ-Opioid Receptor in Mice

Eileen Nguyen, M.D., Ph.D., Michael C. Chiang, M.D., Ph.D., Catherine Nguyen, B.S., Sarah E. Ross, Ph.D.

Anesthesiology. October 2023: 139(4):462–475

https://doi.org/10.1097/ALN.0000000000004668

Published: October 2023

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Articles

Intraoperative Methadone in Next-day Discharge Outpatient Surgery: A Randomized, Double-blinded, Dose-finding Pilot Study

Evan D. Kharasch, M.D., Ph.D., L. Michael Brunt, M.D., Jane Blood, R.N., Helga Komen, M.D.

Anesthesiology. October 2023: 139(4):405–419

https://doi.org/10.1097/ALN.0000000000004663

Published: October 2023

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Articles

Analgesic Effectiveness of Motor-sparing Nerve Blocks for Total Knee Arthroplasty: A Network Meta-analysis

Nasir Hussain, M.D., M.Sc., Richard Brull, M.D., F.R.C.P.C., Chris Vannabouathong, M.Sc., Christopher Robinson, M.D., Steven Zhou, M.D., Ryan S. D’Souza, M.D., Tamara Sawyer, M.L.I.S., Abdullah Sulieman Terkawi, M.D., M.S.(Epi), Faraj W. Abdallah, M.D., M.Sc.

Anesthesiology. October 2023: 139(4):444–461

https://doi.org/10.1097/ALN.0000000000004667

Published: October 2023

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Articles

Best Practice Alerts Informed by Inpatient Opioid Intake to Reduce Opioid Prescribing after Surgery (PRIOR): A Cluster Randomized Multiple Crossover Trial

Megan L. Rolfzen, M.D., Abraham Wick, Pharm.D., Edward J. Mascha, Ph.D., Karan Shah, M.S., Martin Krause, M.D., Ana Fernandez-Bustamante, M.D., Ph.D., Jean S. Kutner, M.D., M.S.P.H., P. Michael Ho, M.D., Ph.D., F.A.C.C., Daniel I. Sessler, M.D., Karsten Bartels, M.D., Ph.D., M.B.A.

Anesthesiology. August 2023: 139(2):186–196

https://doi.org/10.1097/ALN.0000000000004607

Published: August 2023

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Articles

Morphine and Hydromorphone Effects, Side Effects, and Variability: A Crossover Study in Human Volunteers

Konrad Meissner, M.D., Albert Dahan, M.D., Ph.D., Erik Olofsen, Ph.D., Christine Göpfert, M.D., Jane Blood, R.N., B.S.N., Johannes Wieditz, Ph.D., Evan D. Kharasch, M.D., Ph.D.

Anesthesiology. July 2023: 139(1):16–34

https://doi.org/10.1097/ALN.0000000000004567

Published: July 2023

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Articles

Phosphorylated Upstream Frameshift 1–dependent Nonsense-mediated μ-Opioid Receptor mRNA Decay in the Spinal Cord Contributes to the Development of Neuropathic Allodynia–like Behavior in Rats

Ming-Chun Hsieh, Ph.D., Cheng-Yuan Lai, Ph.D., Chou-Ming Yeh, M.D., Ph.D., Po-Sheng Yang, M.D., Ph.D., Jen-Kun Cheng, M.D., Ph.D., Hsueh-Hsiao Wang, Ph.D., Kuan-Hung Lin, Ph.D., Siao-Tong Nie, U.G., Tzer-Bin Lin, Ph.D., Hsien-Yu Peng, Ph.D.

Anesthesiology. June 2023: 138(6):634–655

https://doi.org/10.1097/ALN.0000000000004550

Published: June 2023

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Articles

Uncoupling Pain and Opioid Use after Surgery

Karim Shiraz Ladha, M.D., M.Sc., Kristin L. Schreiber, M.D., Ph.D.

Anesthesiology. May 2023: 138(5):457–459

https://doi.org/10.1097/ALN.0000000000004552

Published: May 2023

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Articles

Prolonged Opioid Use and Pain Outcome and Associated Factors after Surgery under General Anesthesia: A Prospective Cohort Association Multicenter Study

Kai Kuck, Ph.D., Bhiken I. Naik, M.B.B.Ch., M.S.C.R., Karen B. Domino, M.D., M.P.H., Karen L. Posner, Ph.D., Leif Saager, M.D., Ami R. Stuart, Ph.D., Ken B. Johnson, M.D., Salome B. Alpert, Ph.D., Marcel E. Durieux, M.D., Ph.D., Anik K. Sinha, M.S., Chad M. Brummett, M.D., Michael F. Aziz, M.D., Kenneth C. Cummings, III, M.D., John G. Gaudet, M.D., Andrea Kurz, M.D., Mienke Rijsdijk, M.D., Ph.D., Jonathan P. Wanderer, M.D., Nathan L. Pace, M.D., M.Stat., the Multicenter Perioperative Outcomes Group Enhanced Observation Study Investigator Group for the Multicenter Perioperative Outcomes Group Enhanced Observation Study Collaborator Group, Mitchell F. Berman, M.D., M.P.H., Beatriz Raposo Corradini, M.S., Shawn L. Mincer, M.S.W, Sydney E. Rose, M.D., Wilton A. van Klei, M.D., Ph.D., David A. Edwards, M.D., Ph.D., Olivia O.A. Lamers, M.D., Michelle T. Vaughn, M.P.H.

Anesthesiology. May 2023: 138(5):462–476

https://doi.org/10.1097/ALN.0000000000004510

Published: May 2023

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Articles

Carrying Cargo: Preoperative Risk Factors for Persistent Postop Pain & Opioid Use

Holly B. Ende, James P. Rathmell, Jonathan P. Wanderer

Anesthesiology. May 2023: 138(5):A17

https://doi.org/10.1097/ALN.0000000000004564

Published: May 2023

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Articles

Nonopioid Analgesic Prescriptions Filled after Surgery among Older Adults in Ontario, Canada: A Population-based Cohort Study

Naheed K. Jivraj, M.B.B.S., M.Sc., Karim S. Ladha, M.D., M.Sc., Akash Goel, M.D., M.Sc., Andrea Hill, Ph.D., Duminda N. Wijeysundera, M.D., Ph.D., Brian T. Bateman, M.D., M.Sc., Mark Neuman, M.D., M.Sc., Hannah Wunsch, M.D., M.Sc.

Anesthesiology. February 2023: 138(2):195–207

https://doi.org/10.1097/ALN.0000000000004443

Published: February 2023

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Articles

No Benefits of Adding Dexmedetomidine, Ketamine, Dexamethasone, and Nerve Blocks to an Established Multimodal Analgesic Regimen after Total Knee Arthroplasty

Felipe Muñoz-Leyva, M.D., James M. Jack, M.B.B.S., Anuj Bhatia, M.D., F.R.C.P.C., Ki Jinn Chin, M.B.B.S. (Hon), M.Med., F.A.N.Z.C.A., F.R.C.P.C., Rajiv Gandhi, M.D., M.S., F.R.C.S.C., Anahi Perlas, M.D., F.R.C.P.C., Rongyu Jin, M.D., Vincent Chan, M.D., F.R.C.P.C.

Anesthesiology. October 2022: 137(4):459–470

https://doi.org/10.1097/ALN.0000000000004326

Published: October 2022

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Articles

The Early Days: Do Immediate Perioperative Opioid Prescribing Practices Affect Long-Term Opioid Utilization?

Holly B. Ende, James P. Rathmell, Jonathan P. Wanderer

Anesthesiology. August 2022: 137(2):A17

https://doi.org/10.1097/ALN.0000000000004305

Published: August 2022

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Articles

Surgeon Variation in Perioperative Opioid Prescribing and Medium- or Long-term Opioid Utilization after Total Knee Arthroplasty: A Cross-sectional Analysis

Xi Cen, Ph.D., Anupam B. Jena, M.D., Ph.D., Sean Mackey, M.D., Ph.D., Eric C. Sun, M.D., Ph.D.

Anesthesiology. August 2022: 137(2):151–162

https://doi.org/10.1097/ALN.0000000000004259

Published: August 2022

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Articles

Advances in Reversal Strategies of Opioid-induced Respiratory Toxicity

Rutger van der Schrier, M.D., Jack D. C. Dahan, B.Sc., Martijn Boon, M.D., Ph.D., Elise Sarton, M.D., Ph.D., Monique van Velzen, Ph.D., Marieke Niesters, M.D., Ph.D., Albert Dahan, M.D., Ph.D.

Anesthesiology. April 2022: 136(4):618–632

https://doi.org/10.1097/ALN.0000000000004096

Published: April 2022

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Articles

Perioperative Opioids, the Opioid Crisis, and the Anesthesiologist

Daniel B. Larach, M.D., M.S.T.R., M.A., Jennifer M. Hah, M.D., M.S., Chad M. Brummett, M.D.

Anesthesiology. April 2022: 136(4):594–608

https://doi.org/10.1097/ALN.0000000000004109

Published: April 2022

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Articles

Pain and Opioid Consumption and Mobilization after Surgery: Post Hoc Analysis of Two Randomized Trials

Eva Rivas, M.D., Barak Cohen, M.D., Xuan Pu, M.Sc., Li Xiang, M.D., Wael Saasouh, M.D., Guangmei Mao, M.Sc., Paul Minko, B.S., Lauretta Mosteller, B.A., Andrew Volio, M.D., Kamal Maheshwari, M.D., Daniel I. Sessler, M.D., Alparslan Turan, M.D.

Anesthesiology. January 2022: 136(1):115–126

https://doi.org/10.1097/ALN.0000000000004037

Published: January 2022

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Articles

Opioids and Public Health: The Prescription Opioid Ecosystem and Need for Improved Management

Evan D. Kharasch, M.D., Ph.D., J. David Clark, M.D., Ph.D., Jerome M. Adams, M.D., M.P.H.

Anesthesiology. January 2022: 136(1):10–30

https://doi.org/10.1097/ALN.0000000000004065

Published: January 2022

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Articles

Preoperative Opioid Utilization Patterns and Postoperative Opioid Utilization: A Retrospective Cohort Study

Chris A. Rishel, M.D., Ph.D., Martin S. Angst, M.D., Eric C. Sun, M.D., Ph.D.

Anesthesiology. December 2021: 135(6):1015–1026

https://doi.org/10.1097/ALN.0000000000004026

Published: December 2021

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Articles

Persistent Postoperative Opioid Prescription Fulfillment and Peripheral Nerve Blocks for Ambulatory Shoulder Surgery: A Retrospective Cohort Study

Gavin M. Hamilton, M.D., M.Sc., Sarah Tierney, M.D., B.Sc., Reva Ramlogan, M.D., B.Sc., Colin J. L. McCartney, M.B.Ch.B., Ph.D., Lisa A. Bromley, M.D., Daniel I. McIsaac, M.D., M.P.H.

Anesthesiology. November 2021: 135(5):829–841

https://doi.org/10.1097/ALN.0000000000003962

Published: November 2021

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NARROW

Association of Genetic Variants with Postsurgical Pain: A Systematic Review and Meta-analyses

Brainstem Modulation of Nociception by Periaqueductal Gray Neurons Expressing the μ-Opioid Receptor in Mice

Intraoperative Methadone in Next-day Discharge Outpatient Surgery: A Randomized, Double-blinded, Dose-finding Pilot Study

Analgesic Effectiveness of Motor-sparing Nerve Blocks for Total Knee Arthroplasty: A Network Meta-analysis

Best Practice Alerts Informed by Inpatient Opioid Intake to Reduce Opioid Prescribing after Surgery (PRIOR): A Cluster Randomized Multiple Crossover Trial

Morphine and Hydromorphone Effects, Side Effects, and Variability: A Crossover Study in Human Volunteers

Phosphorylated Upstream Frameshift 1–dependent Nonsense-mediated μ-Opioid Receptor mRNA Decay in the Spinal Cord Contributes to the Development of Neuropathic Allodynia–like Behavior in Rats

Uncoupling Pain and Opioid Use after Surgery

Prolonged Opioid Use and Pain Outcome and Associated Factors after Surgery under General Anesthesia: A Prospective Cohort Association Multicenter Study

Carrying Cargo: Preoperative Risk Factors for Persistent Postop Pain & Opioid Use

Nonopioid Analgesic Prescriptions Filled after Surgery among Older Adults in Ontario, Canada: A Population-based Cohort Study

No Benefits of Adding Dexmedetomidine, Ketamine, Dexamethasone, and Nerve Blocks to an Established Multimodal Analgesic Regimen after Total Knee Arthroplasty

The Early Days: Do Immediate Perioperative Opioid Prescribing Practices Affect Long-Term Opioid Utilization?

Surgeon Variation in Perioperative Opioid Prescribing and Medium- or Long-term Opioid Utilization after Total Knee Arthroplasty: A Cross-sectional Analysis

Advances in Reversal Strategies of Opioid-induced Respiratory Toxicity

Perioperative Opioids, the Opioid Crisis, and the Anesthesiologist

Pain and Opioid Consumption and Mobilization after Surgery: Post Hoc Analysis of Two Randomized Trials

Opioids and Public Health: The Prescription Opioid Ecosystem and Need for Improved Management

Preoperative Opioid Utilization Patterns and Postoperative Opioid Utilization: A Retrospective Cohort Study

Persistent Postoperative Opioid Prescription Fulfillment and Peripheral Nerve Blocks for Ambulatory Shoulder Surgery: A Retrospective Cohort Study

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