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Articles

Solubility of Haloether Anesthetics in Human and Animal Blood

Joao H. N. Soares, D.V.M., Robert J. Brosnan, D.V.M., Ph.D., Fabíola B. Fukushima, D.V.M., Joanne Hodges, D.V.M., Hong Liu, M.D.

Anesthesiology. July 2012: 117(1):48–55

DOI: https://doi.org/10.1097/ALN.0b013e3182557cc9

Published: July 2012

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Articles

New Insights into the Mechanism of Methoxyflurane Nephrotoxicity and Implications for Anesthetic Development (Part 1): Identification of the Nephrotoxic Metabolic Pathway

Evan D. Kharasch, M.D., Ph.D., Jesara L. Schroeder, B.S., H Denny Liggitt, D.V.M., Ph.D., Sang B. Park, Ph.D., Dale Whittington, B.S., Pamela Sheffels, B.S.

Anesthesiology. October 2006: 105(4):726–736

DOI: https://doi.org/10.1097/00000542-200610000-00019

Published: October 2006

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Articles

New Insights into the Mechanism of Methoxyflurane Nephrotoxicity and Implications for Anesthetic Development (Part 2): Identification of Nephrotoxic Metabolites

Evan D. Kharasch, M.D., Ph.D., Jesara L. Schroeder, B.S., H Denny Liggitt, D.V.M., Ph.D., Dustin Ensign, Dale Whittington, B.S.

Anesthesiology. October 2006: 105(4):737–745

DOI: https://doi.org/10.1097/00000542-200610000-00020

Published: October 2006

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Articles

Methoxyflurane Revisited: Tale of an Anesthetic from Cradle to Grave

Richard I. Mazze, M.D., Srinivasa N. Raja, M.D.

Anesthesiology. October 2006: 105(4):843–846

DOI: https://doi.org/10.1097/00000542-200610000-00031

Published: October 2006

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Articles

Mechanistic Aspects of Carbon Monoxide Formation from Volatile Anesthetics

Pamela J. Baxter, PhD, Kyle Garton, BS, Evan D. Kharasch, MD, PhD

Anesthesiology. October 1998: 89(4):929–941

DOI: https://doi.org/10.1097/00000542-199810000-00018

Published: October 1998

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Articles

Human Kidney Methoxyflurane and Sevoflurane Metabolism : Intrarenal Fluoride Production as a Possible Mechanism of Methoxyflurane Nephrotoxicity

Evan D. Kharasch, MD, PhD, Douglas C. Hankins, MA, Kenneth E. Thummel, PhD

Anesthesiology. March 1995: 82(3):689–699

DOI: https://doi.org/10.1097/00000542-199503000-00011

Published: March 1995

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Articles

Identification of Cytochrome P450 2E1 as the Predominant Enzyme Catalyzing Human Liver Microsomal Defluorination of Sevoflurane, Isoflurane, and Methoxyflurane

Evan D. Kharasch, M.D. Ph.D., Kenneth E. Thummel, Ph.D.

Anesthesiology. October 1993: 79(4):795–807

DOI: https://doi.org/10.1097/00000542-199310000-00023

Published: October 1993

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Articles

Ultra long-duration Local Anesthesia Produced by Injection of Lecithin-coated Methoxyflurane Microdroplets

Duncan H. Haynes, Ph.D., Anthony F. Kirkpatrick, M.D., Ph.D.

Anesthesiology. November 1985: 63(5):490–499

DOI: https://doi.org/10.1097/00000542-198511000-00004

Published: November 1985

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Articles

Enflurane, Isoflurane, and Methoxyflurane Metabolism in Rat Hepatic Microsomes from Ethanol-treated Animals

Russell A. Van Dyke, Ph.D.

Anesthesiology. March 1983: 58(3):221–224

DOI: https://doi.org/10.1097/00000542-198303000-00003

Published: March 1983

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Articles

Densities of Liquid Halothane, Methoxyflurane, and Enflurane between 0° and 35°C

B. Korman, B.Sc., M.B.B.S., F.F.A.R.A.C.S., I. M. Ritchie, Ph.D., F.R.A.C.I.

Anesthesiology. July 1982: 57(1):42–43

DOI: https://doi.org/10.1097/00000542-198207000-00011

Published: July 1982

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Articles

Deuterated Methoxyflurane Anesthesia and Renal Function in Fischer 344 Rats

Jeffrey M. Baden, M.B., Susan A. Rice, Ph.D., Richard I. Mazze, M.D.

Anesthesiology. March 1982: 56(3):203–206

DOI: https://doi.org/10.1097/00000542-198203000-00009

Published: March 1982

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Articles

Renal Function in Newborns and Mothers Exposed to Methoxyflurane Analgesia for Labor and Delivery

RICHARD B. CLARK, M.D., ALICE G. BEARD, M.D., DOLA S. THOMPSON, M.D.

Anesthesiology. November 1979: 51(5):464–466

DOI: https://doi.org/10.1097/00000542-197911000-00020

Published: November 1979

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Articles

Serum Cholinesterase Activity Following the Use of Methoxyflurane in Obstetrics

R. J. Palahniuk, M.D., M. Cumming, R.N., B.Sc.

Anesthesiology. December 1977: 47(6):520–521

DOI: https://doi.org/10.1097/00000542-197712000-00011

Published: December 1977

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Articles

Maternal and Neonatal Plasma Inorganic Fluoride Levels after Methoxyflurane Analgesia for Labor and Delivery

Richard B. Clark, M.D., Alice G. Beard, M.D., Dola S. Thompson, M.D., David L. Barclay, M.D.

Anesthesiology. July 1976: 45(1):88–90

DOI: https://doi.org/10.1097/00000542-197607000-00016

Published: July 1976

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Articles

Methoxyflurane Metabolism

RICHARD I. MAZZE, M. D., BEN A. HITT, PH.D.

Anesthesiology. May 1976: 44(5):369–370

DOI: https://doi.org/10.1097/00000542-197605000-00001

Published: May 1976

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Articles

Hepatitis Following the Use of Methoxyflurane in Obstetric Analgesia

DEVORAH RUBINGER, M.D., J. T. DAVIDSON, F.F.A.R.C.S., R. N. MELMED, M.R.C.P.

Anesthesiology. November 1975: 43(5):593–594

DOI: https://doi.org/10.1097/00000542-197511000-00025

Published: November 1975

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Articles

Renal Effects and Metabolism of Sevoflurane in Fischer 344 Rats: An In-vivo and In-vitro Comparison with Methoxyflurane

Thomas L. Cook, M.D., William J. Beppu, M.D., Ben A. Hitt, Ph.D., Jon C. Kosek, M.D., Richard I. Mazze, M.D.

Anesthesiology. July 1975: 43(1):70–76

DOI: https://doi.org/10.1097/00000542-197507000-00015

Published: July 1975

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Articles

Metabolism in Vitro of Enflurane, Isoflurane, and Methoxyflurane

L. Richard Greenstein, M.D., Ben A. Hitt, Ph.D., Richard I. Mazze, M.D.

Anesthesiology. April 1975: 42(4):420–424

DOI: https://doi.org/10.1097/00000542-197504000-00010

Published: April 1975

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Articles

Anesthetic Biotransformation and Renal Function in Obese Patients during and after Methoxyflurane or Halothane Anesthesia

Steven R. Young, M.D., Robert K. Stoelting, M.D., Christine Peterson, R.N., James A. Madura, M.D.

Anesthesiology. April 1975: 42(4):451–457

DOI: https://doi.org/10.1097/00000542-197504000-00015

Published: April 1975

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Articles

Methoxyflurane Anesthesia in Pediatric Patients: Evaluation of Anesthetic Metabolism and Renal Function

Robert K. Stoelting, M.D., Christine Peterson, R.N.

Anesthesiology. January 1975: 42(1):26–29

DOI: https://doi.org/10.1097/00000542-197501000-00005

Published: January 1975

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NARROW

Solubility of Haloether Anesthetics in Human and Animal Blood

New Insights into the Mechanism of Methoxyflurane Nephrotoxicity and Implications for Anesthetic Development (Part 1): Identification of the Nephrotoxic Metabolic Pathway

New Insights into the Mechanism of Methoxyflurane Nephrotoxicity and Implications for Anesthetic Development (Part 2): Identification of Nephrotoxic Metabolites

Methoxyflurane Revisited: Tale of an Anesthetic from Cradle to Grave

Mechanistic Aspects of Carbon Monoxide Formation from Volatile Anesthetics

Human Kidney Methoxyflurane and Sevoflurane Metabolism : Intrarenal Fluoride Production as a Possible Mechanism of Methoxyflurane Nephrotoxicity

Identification of Cytochrome P450 2E1 as the Predominant Enzyme Catalyzing Human Liver Microsomal Defluorination of Sevoflurane, Isoflurane, and Methoxyflurane

Ultra long-duration Local Anesthesia Produced by Injection of Lecithin-coated Methoxyflurane Microdroplets

Enflurane, Isoflurane, and Methoxyflurane Metabolism in Rat Hepatic Microsomes from Ethanol-treated Animals

Densities of Liquid Halothane, Methoxyflurane, and Enflurane between 0° and 35°C

Deuterated Methoxyflurane Anesthesia and Renal Function in Fischer 344 Rats

Renal Function in Newborns and Mothers Exposed to Methoxyflurane Analgesia for Labor and Delivery

Serum Cholinesterase Activity Following the Use of Methoxyflurane in Obstetrics

Maternal and Neonatal Plasma Inorganic Fluoride Levels after Methoxyflurane Analgesia for Labor and Delivery

Methoxyflurane Metabolism

Hepatitis Following the Use of Methoxyflurane in Obstetric Analgesia

Renal Effects and Metabolism of Sevoflurane in Fischer 344 Rats: An In-vivo and In-vitro Comparison with Methoxyflurane

Metabolism in Vitro of Enflurane, Isoflurane, and Methoxyflurane

Anesthetic Biotransformation and Renal Function in Obese Patients during and after Methoxyflurane or Halothane Anesthesia

Methoxyflurane Anesthesia in Pediatric Patients: Evaluation of Anesthetic Metabolism and Renal Function

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