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Adverse Mechanical Ventilation and Pneumococcal Pneumonia Induce Immune and Mitochondrial Dysfunctions Mitigated by Mesenchymal Stem Cells in Rabbits

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Mathieu Blot, M.D., Ph.D., Marine Jacquier, M.Sc., Laure-Anne Pauchard, Ph.D., Chloé Rebaud, M.Sc., Charline Marlin, M.Sc., Camille Hamelle, M.Sc., Amandine Bataille, M.Sc., Delphine Croisier, Pharm.D., Ph.D., Charles Thomas, Ph.D., Antoine Jalil, Ms.C., Hélène Mirfendereski, Eng., Lionel Piroth, M.D., Ph.D., Pascal Chavanet, M.D., Ph.D., Danielle Bensoussan, Pharm.D., Ph.D., Caroline Laroye, Pharm.D., Ph.D., Loïc Reppel, Pharm.D., Ph.D., Pierre-Emmanuel Charles, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. February 2022: 136(2):293–313
DOI: https://doi.org/10.1097/ALN.0000000000004083
Published: February 2022
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Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Systemic Sepsis in Part by Enhancing Peritoneal Macrophage Bacterial Killing via Heme Oxygenase-1 Induction in Rats

Mirjana Jerkic, M.D., Ph.D., Stéphane Gagnon, M.Sc., Razieh Rabani, B.Sc., Ph.D., Taylor Ward-Able, B.Sc., Claire Masterson, M.Sc., Ph.D., Gail Otulakowski, B.Sc., Ph.D., Gerard F. Curley, M.B., Ph.D., F.C.A.I., John Marshall, M.D., F.R.C.S.C., F.A.C.S., F.C.A.H.S., Brian P. Kavanagh, M.D., John G. Laffey, M.D., M.A., F.C.A.I.
Publication: Anesthesiology
Anesthesiology. January 2020: 132(1):140–154
DOI: https://doi.org/10.1097/ALN.0000000000003018
Published: January 2020
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Extracellular Vesicles from Interferon-γ–primed Human Umbilical Cord Mesenchymal Stromal Cells Reduce Escherichia coli –induced Acute Lung Injury in Rats

Amir K. Varkouhi, M.D., Ph.D., Mirjana Jerkic, M.D., Ph.D., Lindsay Ormesher, B.Sc., Stéphane Gagnon, M.Sc., Sakshi Goyal, B.Sc., Razieh Rabani, B.Sc., Ph.D., Claire Masterson, M.Sc., Ph.D., Chris Spring, B.Sc., Paul Z. Chen, B.A.Sc., Frank X. Gu, Ph.D., Claudia C. dos Santos, M.D., Gerard F. Curley, M.B., Ph.D., F.C.A.I., John G. Laffey, M.D., M.A., F.C.A.I.
Publication: Anesthesiology
Anesthesiology. May 2019: 130(5):778–790
DOI: https://doi.org/10.1097/ALN.0000000000002655
Published: May 2019
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Syndecan-2–positive, Bone Marrow–derived Human Mesenchymal Stromal Cells Attenuate Bacterial-induced Acute Lung Injury and Enhance Resolution of Ventilator-induced Lung Injury in Rats

Claire Masterson, Ph.D., James Devaney, Ph.D., Shahd Horie, Ph.D., Lisa O’Flynn, Ph.D., Laura Deedigan, Ph.D., Steve Elliman, Ph.D., Frank Barry, Ph.D., Timothy O’Brien, M.D., Ph.D., Daniel O’Toole, Ph.D., John G. Laffey, M.D., M.A., F.C.A.I.
Publication: Anesthesiology
Anesthesiology. September 2018: 129(3):502–516
DOI: https://doi.org/10.1097/ALN.0000000000002327
Published: September 2018
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Mesenchymal Stem Cell Therapy for Acute Respiratory Distress Syndrome: A Light at the End of the Tunnel?

Jae-Woo Lee, M.D., Patricia R.M. Rocco, M.D., Ph.D., Paolo Pelosi, M.D.
Publication: Anesthesiology
Anesthesiology. February 2015: 122(2):238–240
DOI: https://doi.org/10.1097/ALN.0000000000000546
Published: February 2015
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Therapeutic Efficacy of Human Mesenchymal Stromal Cells in the Repair of Established Ventilator-induced Lung Injury in the Rat

Mairead Hayes, M.D., F.C.A.I., Claire Masterson, Ph.D., James Devaney, Ph.D., Frank Barry, Ph.D., Steve Elliman, Ph.D., Timothy O’Brien, M.D., Ph.D., Daniel O’Toole, Ph.D., Gerard F. Curley, M.B., Ph.D., F.C.A.I., John G. Laffey, M.D., M.A., F.C.A.I.
Publication: Anesthesiology
Anesthesiology. February 2015: 122(2):363–373
DOI: https://doi.org/10.1097/ALN.0000000000000545
Published: February 2015
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Transforming High Risk to High Yield

Karsten Bartels, M.D., Almut Grenz, M.D., Ph.D., Holger K. Eltzschig, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. May 2014: 120(5):1072–1074
DOI: https://doi.org/10.1097/ALN.0000000000000217
Published: May 2014
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Effects of Intratracheal Mesenchymal Stromal Cell Therapy during Recovery and Resolution after Ventilator-induced Lung Injury

Gerard F. Curley, M.B., Ph.D., F.C.A.R.C.S.I., Bilal Ansari, M.B., F.C.A.R.C.S.I., Mairead Hayes, M.B., F.C.A.R.C.S.I., James Devaney, Ph.D., Claire Masterson, B.Sc., Aideen Ryan, Ph.D., Frank Barry, Ph.D., Timothy O’Brien, M.D., Ph.D., Daniel O’ Toole, Ph.D., John G. Laffey, M.D., F.C.A.R.C.S.I.
Publication: Anesthesiology
Anesthesiology. April 2013: 118(4):924–932
DOI: https://doi.org/10.1097/ALN.0b013e318287ba08
Published: April 2013
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Antiinflammation Effect of Human Placental Multipotent Mesenchymal Stromal Cells Is Mediated by Prostaglandin E 2 via   a Myeloid Differentiation Primary Response Gene 88-dependent Pathway

Chie-Pein Chen, M.D., Ph.D., Pei-Shan Tsai, Ph.D., Chun-Jen Huang, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. September 2012: 117(3):568–579
DOI: https://doi.org/10.1097/ALN.0b013e31826150a9
Published: September 2012
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Antiproliferative Effects of Local Anesthetics on Mesenchymal Stem Cells: Potential Implications for Tumor Spreading and Wound Healing

Eliana Lucchinetti, Ph.D., Ahmed E. Awad, M.D., Mamoona Rahman, M.D., Jianhua Feng, M.D., Ph.D., Phing-How Lou, Ph.D., Liyan Zhang, Ph.D., Lavinia Ionescu, M.D., Hélène Lemieux, Ph.D., Bernard Thébaud, M.D., Michael Zaugg, M.D., M.B.A.
Publication: Anesthesiology
Anesthesiology. April 2012: 116(4):841–856
DOI: https://doi.org/10.1097/ALN.0b013e31824babfe
Published: April 2012
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