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Evaluation of malignant hyperthermia features in patients with pathogenic or likely pathogenic RYR1 variants disclosedthrough a population genomic screening program

Kristen D. Yu, M.S., Megan N. Betts, M.S., Gretchen M. Urban, M.S., Marci L.B. Schwartz, Sc.M., Tanisha O. Robinson, M.D., Robert J. Moyer, M.D., Scott W. Taddonio, D.O., Anasuya Vasudevan, M.D., Alicia Johns, Ph.D., Amy C. Sturm, M.S., Melissa A. Kelly, M.S., Marc S. Williams, M.D., S. Mark Poler, M.D., Adam H. Buchanan, M.S., M.P.H.

Anesthesiology. October 2023: 10.1097/ALN.0000000000004786

https://doi.org/10.1097/ALN.0000000000004786

Published: October 2023

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Articles

Altered [Ca 2+ ] Regulation in Cortical Neurons of Mice Susceptible to Malignant Hyperthermia: An In Vivo Study

Arkady Uryash, M.D, Ph.D., Jose A. Adams, M.D., Jose R. Lopez, M.D., Ph.D.

Anesthesiology. October 2023: 139(4):543–545

https://doi.org/10.1097/ALN.0000000000004676

Published: October 2023

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Articles

Referral Indications for Malignant Hyperthermia Susceptibility Diagnostics in Patients without Adverse Anesthetic Events in the Era of Next-generation Sequencing

Luuk R. van den Bersselaar, M.D.,M.Sc., Anna Hellblom, M.D., M.Sc., Mejdan Gashi, B.Sc., Erik-Jan Kamsteeg, Ph.D., Nicol C. Voermans, M.D., Ph.D., Heinz Jungbluth, M.D., Ph.D., Joris de Puydt, M.D., M.Sc., Luc Heytens, M.D., Ph.D., Sheila Riazi, M.D., M.Sc., Marc M. J. Snoeck, M.D., Ph.D.

Anesthesiology. June 2022: 136(6):940–953

https://doi.org/10.1097/ALN.0000000000004199

Published: June 2022

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Articles

Serendipity: Being in the Right Place at the Right Time

Lawrence J. Saidman, M.D.

Anesthesiology. May 2022: 136(5):823–826

https://doi.org/10.1097/ALN.0000000000004140

Published: May 2022

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Articles

Dantrolene Available in China for Malignant Hyperthermia Treatment

Zhengqian Li, M.D., Ph.D., Kaixi Liu, M.D., Xiangyang Guo, M.D.

Anesthesiology. March 2022: 136(3):515–516

https://doi.org/10.1097/ALN.0000000000003998

Published: March 2022

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Articles

Molecular Modification of Transient Receptor Potential Canonical 6 Channels Modulates Calcium Dyshomeostasis in a Mouse Model Relevant to Malignant Hyperthermia

Jose Rafael Lopez, M.D., Ph.D., Arkady Uryash, M.D., Ph.D., Jose Adams, M.D., Philip M. Hopkins, M.D., F.R.C.A., Paul D. Allen, M.D., Ph.D.

Anesthesiology. February 2021: 134(2):234–247

https://doi.org/10.1097/ALN.0000000000003635

Published: February 2021

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Articles

Genomic Screening for Malignant Hyperthermia Susceptibility

Leslie G. Biesecker, M.D., Robert T. Dirksen, Ph.D., Thierry Girard, M.D., Philip M. Hopkins, M.D., Sheila Riazi, M.D., Henry Rosenberg, M.D., Kathryn Stowell, Ph.D., James Weber, Ph.D.

Anesthesiology. December 2020: 133(6):1277–1282

https://doi.org/10.1097/ALN.0000000000003547

Published: December 2020

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Articles

Transient Receptor Potential Cation Channels and Calcium Dyshomeostasis in a Mouse Model Relevant to Malignant Hyperthermia

Jose Rafael Lopez, M.D., Ph.D., Vikas Kaura, M.D., Phillip Hopkins, M.D., Xiaochen Liu, Ph.D., Arkady Uryach, M.D., Ph.D., Jose Adams, M.D., Paul D. Allen, M.D., Ph.D

Anesthesiology. August 2020: 133(2):364–376

https://doi.org/10.1097/ALN.0000000000003387

Published: August 2020

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Articles

An Assessment of Penetrance and Clinical Expression of Malignant Hyperthermia in Individuals Carrying Diagnostic Ryanodine Receptor 1 Gene Mutations

Carlos A. Ibarra Moreno, M.D., Ph.D., Sally Hu, M.D., Natalia Kraeva, Ph.D., Frank Schuster, M.D., Stephan Johannsen, M.D., Henrik Rueffert, M.D., Werner Klingler, M.D., Ph.D., Luc Heytens, M.D., Ph.D., Sheila Riazi, M.Sc., M.D.

Anesthesiology. November 2019: 131(5):983–991

https://doi.org/10.1097/ALN.0000000000002813

Published: November 2019

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Articles

Mission Impossible or Mission Futile?: Estimating Penetrance for Malignant Hyperthermia

Marie-Anne Shaw, Ph.D., Philip M. Hopkins, M.B.B.S., M.D., F.R.C.A.

Anesthesiology. November 2019: 131(5):957–959

https://doi.org/10.1097/ALN.0000000000002884

Published: November 2019

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Articles

Succinylcholine Use and Dantrolene Availability for Malignant Hyperthermia Treatment: Database Analyses and Systematic Review

Marilyn Green Larach, M.D., F.A.A.P., Thomas T. Klumpner, M.D., Barbara W. Brandom, M.D., Michelle T. Vaughn, M.P.H., Kumar G. Belani, M.B.B.S., M.S., F.A.A.P., Andrew Herlich, D.M.D., M.D., F.A.A.P., F.A.S.A., Tae W. Kim, M.D., M.E.H.P., Janine Limoncelli, M.D., Sheila Riazi, M.Sc., M.D., FRCPC, Erica L. Sivak, M.D., John Capacchione, M.D., Darlene Mashman, M.D., Sachin Kheterpal, M.D., M.B.A., on behalf of the Multicenter Perioperative Outcomes Group , Fabian Kooij, M.D., Janet Wilczak, M.D., Roy Soto, M.D., Joshua Berris, D.O., Zachary Price, M.D., Steven Lins, M.D., Peter Coles, M.D., John M. Harris, M.D., Kenneth C. Cummings, III, M.D., M.S., Mitchell F. Berman, M.D., Masakatsu Nanamori, M.D., Bruce T. Adelman, M.D., Christopher Wedeven, M.D., John LaGorio, M.D., Patrick J. McCormick, M.D., M.Eng., Simon Tom, M.D., Michael F. Aziz, M.D., Traci Coffman, M.D., Terri A. Ellis, II, M.D., Susan Molina, M.D., William Peterson, M.D., Sean C. Mackey, M.D., Ph.D., Wilton A. van Klei, M.D., Ph.D., Adit A. Ginde, M.D., M.P.H., Daniel A. Biggs, M.D., M.Sc., Mark D. Neuman, M.D., M.Sc., Robert M. Craft, M.D., Nathan L. Pace, M.D., M.Stat., William C. Paganelli, M.D., Ph.D., Marcel E. Durieux, M.D., Ph.D., Bala J. Nair, Ph.D., Jonathan P. Wanderer, M.D., Scott A. Miller, M.D., Daniel L. Helsten, M.D., Zachary A. Turnbull, M.D., Robert B. Schonberger, M.D., M.H.S.

Anesthesiology. January 2019: 130(1):41–54

https://doi.org/10.1097/ALN.0000000000002490

Published: January 2019

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Articles

Ultrasound Elastography for Rapid, Real-time Detection of Localized Muscular Reaction in Malignant Hyperthermia–susceptible Pigs

Stephan Johannsen, M.D., Ismail Türkmeneli, M.D., Susanne Isbary, M.D., Norbert Roewer, M.D., Frank Schuster, M.D.

Anesthesiology. November 2018: 129(5):989–999

https://doi.org/10.1097/ALN.0000000000002424

Published: November 2018

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Articles

Dantrolene and Malignant Hyperthermia Carts: Do We Need Them on Maternity Units?

Cynthia A. Wong, M.D.

Anesthesiology. August 2018: 129(2):225–227

https://doi.org/10.1097/ALN.0000000000002279

Published: August 2018

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Articles

Cost-benefit Analysis of Maintaining a Fully Stocked Malignant Hyperthermia Cart versus an Initial Dantrolene Treatment Dose for Maternity Units

Phi T. Ho, M.D., M.B.A., Brendan Carvalho, M.B.B.Ch., F.R.C.A., M.D.C.H., Eric C. Sun, M.D., Ph.D., Alex Macario, M.D., M.B.A., Edward T. Riley, M.D.

Anesthesiology. August 2018: 129(2):249–259

https://doi.org/10.1097/ALN.0000000000002231

Published: August 2018

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Articles

Malignant Hyperthermia Susceptibility and Related Diseases

Ronald S. Litman, D.O., Sarah M. Griggs, B.S., James J. Dowling, M.D., Ph.D., Sheila Riazi, M.D.

Anesthesiology. January 2018: 128(1):159–167

https://doi.org/10.1097/ALN.0000000000001877

Published: January 2018

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Articles

Malignant Hyperthermia in the Post-Genomics Era: New Perspectives on an Old Concept

Sheila Riazi, M.Sc., M.D., Natalia Kraeva, Ph.D., Philip M. Hopkins, M.D., F.R.C.A.

Anesthesiology. January 2018: 128(1):168–180

https://doi.org/10.1097/ALN.0000000000001878

Published: January 2018

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Articles

A Primer for Diagnosing and Managing Malignant Hyperthermia Susceptibility

Marilyn Green Larach, M.D., F.A.A.P.

Anesthesiology. January 2018: 128(1):8–10

https://doi.org/10.1097/ALN.0000000000001879

Published: January 2018

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Articles

Oxford Handbook of Anaesthesia, 4th Edition.

Philip Lebowitz, M.D., M.B.A.

Anesthesiology. July 2016: 125(1):258

https://doi.org/10.1097/ALN.0000000000001141

Published: July 2016

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Articles

Malignant Hyperthermia in the Ambulatory Surgery Center: How Should We Prepare?

Ronald S. Litman, D.O., Girish P. Joshi, M.B.B.S., M.D., F.F.A.R.C.S.I.

Anesthesiology. June 2014: 120(6):1306–1308

https://doi.org/10.1097/ALN.0000000000000256

Published: June 2014

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Articles

Cost-effectiveness Analysis of Stocking Dantrolene in Ambulatory Surgery Centers for the Treatment of Malignant Hyperthermia

Taiwo Aderibigbe, M.D., Barbara H. Lang, M.P.H., Henry Rosenberg, M.D., Qixuan Chen, Ph.D., Guohua Li, M.D., Dr.P.H.

Anesthesiology. June 2014: 120(6):1333–1338

https://doi.org/10.1097/ALN.0000000000000257

Published: June 2014

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NARROW

Evaluation of malignant hyperthermia features in patients with pathogenic or likely pathogenic RYR1 variants disclosedthrough a population genomic screening program

Altered [Ca 2+ ] Regulation in Cortical Neurons of Mice Susceptible to Malignant Hyperthermia: An In Vivo Study

Referral Indications for Malignant Hyperthermia Susceptibility Diagnostics in Patients without Adverse Anesthetic Events in the Era of Next-generation Sequencing

Serendipity: Being in the Right Place at the Right Time

Dantrolene Available in China for Malignant Hyperthermia Treatment

Molecular Modification of Transient Receptor Potential Canonical 6 Channels Modulates Calcium Dyshomeostasis in a Mouse Model Relevant to Malignant Hyperthermia

Genomic Screening for Malignant Hyperthermia Susceptibility

Transient Receptor Potential Cation Channels and Calcium Dyshomeostasis in a Mouse Model Relevant to Malignant Hyperthermia

An Assessment of Penetrance and Clinical Expression of Malignant Hyperthermia in Individuals Carrying Diagnostic Ryanodine Receptor 1 Gene Mutations

Mission Impossible or Mission Futile?: Estimating Penetrance for Malignant Hyperthermia

Succinylcholine Use and Dantrolene Availability for Malignant Hyperthermia Treatment: Database Analyses and Systematic Review

Ultrasound Elastography for Rapid, Real-time Detection of Localized Muscular Reaction in Malignant Hyperthermia–susceptible Pigs

Dantrolene and Malignant Hyperthermia Carts: Do We Need Them on Maternity Units?

Cost-benefit Analysis of Maintaining a Fully Stocked Malignant Hyperthermia Cart versus an Initial Dantrolene Treatment Dose for Maternity Units

Malignant Hyperthermia Susceptibility and Related Diseases

Malignant Hyperthermia in the Post-Genomics Era: New Perspectives on an Old Concept

A Primer for Diagnosing and Managing Malignant Hyperthermia Susceptibility

Oxford Handbook of Anaesthesia, 4th Edition.

Malignant Hyperthermia in the Ambulatory Surgery Center: How Should We Prepare?

Cost-effectiveness Analysis of Stocking Dantrolene in Ambulatory Surgery Centers for the Treatment of Malignant Hyperthermia

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