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Compound A Uptake and Metabolism to Mercapturic Acids and 3,3,3-Trifluoro-2-fluoromethoxypropanoic Acid during Low-flow Sevoflurane Anesthesia   : Biomarkers for Exposure, Risk Assessment, and Interspecies Comparison

Evan D. Kharasch, M.D., Ph.D., Carole Jubert, Ph.D.
Publication: Anesthesiology
Anesthesiology. November 1999: 91(5):1267
DOI: https://doi.org/10.1097/00000542-199911000-00017
Published: November 1999
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Immunochemical Evidence against the Involvement of Cysteine Conjugate β-lyase in Compound A Nephrotoxicity in Rats

Dolores B. Njoku, MD, Lance R. Pohl, PharmD, PhD, Edward A. Sokoloski, BS, Michael R. Marchick, Craig B. Borkowf, PhD, Jackie L. Martin, MD
Publication: Anesthesiology
Anesthesiology. February 1999: 90(2):458–469
DOI: https://doi.org/10.1097/00000542-199902000-00021
Published: February 1999
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Role of the Renal Cysteine Conjugate β-Lyase Pathway in Inhaled Compound A Nephrotoxicity in Rats

Evan D. Kharasch, MD, PhD, Gary M. Hoffman, BA, David Thorning, MD, Douglas C. Hankins, MA, Cormac G. Kilty, PhD
Publication: Anesthesiology
Anesthesiology. June 1998: 88(6):1624–1633
DOI: https://doi.org/10.1097/00000542-199806000-00027
Published: June 1998
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Cysteine Conjugate β-Lyase-Dependent Metabolism of Compound A (2-[fluoromethoxy]-1,1,3,3,3-pentafluoro-1-propene) in Human Subjects Anesthetized with Sevoflurane and in Rats Given Compound A

Ramaswamy A. Iyer, PhD, Edward J. Frink, MD, Thomas J. Ebert, MD, PhD, M. W. Anders, DM, PhD
Publication: Anesthesiology
Anesthesiology. March 1998: 88(3):611–618
DOI: https://doi.org/10.1097/00000542-199803000-00009
Published: March 1998
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