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Lung Injury Is Induced by Abrupt Increase in Respiratory Rate but Prevented by Recruitment Maneuver in Mild Acute Respiratory Distress Syndrome in Rats

Paulo Henrique Xavier, M.D., Ana Carolina Fernandes Fonseca, M.D., Leonardo Alves Gonçalves, M.D., Giselle Cavalho de Sousa, M.D., Mariana Coelho da Silva, M.D., Raquel Ferreira de Magalhães Sacramento, Ph.D., Cynthia dos Santos Samary, Ph.D., Mayck Medeiros, B.Sc., Fernanda Ferreira Cruz, M.D., Ph.D., Vera Luiza Capelozzi, M.D., Ph.D., Nathane Satanna Felix, M.D., Ph.D., Paolo Pelosi, M.D., John J. Marini, M.D., Patrícia Rieken Macêdo Rocco, M.D., Ph.D., Pedro Leme Silva, Ph.D.

Anesthesiology. April 2023: 138(4):420–435

https://doi.org/10.1097/ALN.0000000000004479

Published: April 2023

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Articles

Mechanical Power: Correlate or Cause of Ventilator-induced Lung Injury?

Marcelo Gama de Abreu, M.D., M.Sc., Ph.D., DESAIC, Daniel I. Sessler, M.D.

Anesthesiology. July 2022: 137(1):6–8

https://doi.org/10.1097/ALN.0000000000004240

Published: July 2022

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Articles

Mechanical Power during General Anesthesia and Postoperative Respiratory Failure: A Multicenter Retrospective Cohort Study

Peter Santer, M.D., D.Phil., Luca J. Wachtendorf, cand.med., Aiman Suleiman, M.D., M.Sc., Timothy T. Houle, Ph.D., Philipp Fassbender, M.D., Eduardo L. Costa, M.D., Daniel Talmor, M.D., M.P.H., Matthias Eikermann, M.D., Ph.D., Elias Baedorf-Kassis, M.D., Maximilian S. Schaefer, M.D.

Anesthesiology. July 2022: 137(1):41–54

https://doi.org/10.1097/ALN.0000000000004256

Published: July 2022

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Articles

Death-associated Protein Kinase 1 Mediates Ventilator-induced Lung Injury in Mice by Promoting Alveolar Epithelial Cell Apoptosis

Yaxin Wang, M.D., Ph.D., Yiyi Yang, M.D., Lin Chen, M.D., Ph.D., Wei Xiong, M.D., Ph.D., Limin Song, M.D., Ph.D., Bo Li, M.D., Ting Zhou, M.D., Ph.D., Lei Pei, Ph.D., Shiying Yuan, M.D., Ph.D., Shanglong Yao, M.D., Ph.D., You Shang, M.D., Ph.D.

Anesthesiology. October 2020: 133(4):905–918

https://doi.org/10.1097/ALN.0000000000003464

Published: October 2020

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Articles

Does Iso-mechanical Power Lead to Iso-lung Damage?: An Experimental Study in a Porcine Model

Francesco Vassalli, M.D., Iacopo Pasticci, M.D., Federica Romitti, M.D., Eleonora Duscio, M.D., David Jerome Aßmann, M.S., Hannah Grünhagen, M.S., Francesco Vasques, M.D., Matteo Bonifazi, M.D., Mattia Busana, M.D., Matteo Maria Macrì, M.D., Lorenzo Giosa, M.D., Verena Reupke, D.V.M., Peter Herrmann, M.Sc., Günter Hahn, M.Sc., Orazio Leopardi, M.D., Onnen Moerer, M.D., Michael Quintel, M.D., John J. Marini, M.D., Luciano Gattinoni, M.D., F.R.C.P.

Anesthesiology. May 2020: 132(5):1126–1137

https://doi.org/10.1097/ALN.0000000000003189

Published: May 2020

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Articles

Understanding the Mysteries of Mechanical Power

Pedro L. Silva, Ph.D., Paolo Pelosi, M.D., F.E.R.S., Patricia R. M. Rocco, M.D., Ph.D.

Anesthesiology. May 2020: 132(5):949–950

https://doi.org/10.1097/ALN.0000000000003222

Published: May 2020

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Articles

In Memoriam: Brian Kavanagh, 1962 to 2019

Beverley A. Orser, M.D., Ph.D., Laurent Brochard, M.D., Ph.D.

Anesthesiology. October 2019: 131(4):759–761

https://doi.org/10.1097/ALN.0000000000002944

Published: October 2019

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Articles

Syndecan-2–positive, Bone Marrow–derived Human Mesenchymal Stromal Cells Attenuate Bacterial-induced Acute Lung Injury and Enhance Resolution of Ventilator-induced Lung Injury in Rats

Claire Masterson, Ph.D., James Devaney, Ph.D., Shahd Horie, Ph.D., Lisa O’Flynn, Ph.D., Laura Deedigan, Ph.D., Steve Elliman, Ph.D., Frank Barry, Ph.D., Timothy O’Brien, M.D., Ph.D., Daniel O’Toole, Ph.D., John G. Laffey, M.D., M.A., F.C.A.I.

Anesthesiology. September 2018: 129(3):502–516

https://doi.org/10.1097/ALN.0000000000002327

Published: September 2018

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Articles

Continuous Negative Abdominal Pressure Reduces Ventilator-induced Lung Injury in a Porcine Model

Takeshi Yoshida, M.D., Ph.D., Doreen Engelberts, Gail Otulakowski, Ph.D., Bhushan Katira, M.D., Martin Post, Ph.D., Niall D. Ferguson, M.D., Laurent Brochard, M.D., Ph.D., Marcelo B. P. Amato, M.D., Ph.D., Brian P. Kavanagh, M.B.

Anesthesiology. July 2018: 129(1):163–172

https://doi.org/10.1097/ALN.0000000000002236

Published: July 2018

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Articles

Energetics and the Root Mechanical Cause for Ventilator-induced Lung Injury

John J. Marini, M.D., Luciano Gattinoni, M.D.

Anesthesiology. June 2018: 128(6):1062–1064

https://doi.org/10.1097/ALN.0000000000002203

Published: June 2018

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Articles

Biologic Impact of Mechanical Power at High and Low Tidal Volumes in Experimental Mild Acute Respiratory Distress Syndrome

Raquel S. Santos, Ph.D., Ligia de A. Maia, Ph.D., Milena V. Oliveira, M.Sc., Cíntia L. Santos, M.D., Ph.D., Lillian Moraes, Ph.D., Eliete F. Pinto, R.T., Cynthia dos S. Samary, Ph.D., Joana A. Machado, M.S., Anna Carolinna Carvalho, M.S., Marcos Vinícius de S. Fernandes, M.S., Vanessa Martins, Ph.D., Vera L. Capelozzi, M.D., Ph.D., Marcelo M. Morales, M.D., Ph.D., Thea Koch, M.D., Ph.D., Marcelo Gama de Abreu, M.D., Ph.D., Paolo Pelosi, M.D., F.E.R.S., Pedro L. Silva, Ph.D., Patricia R. M. Rocco, M.D., Ph.D.

Anesthesiology. June 2018: 128(6):1193–1206

https://doi.org/10.1097/ALN.0000000000002143

Published: June 2018

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Articles

One-hit Models of Ventilator-induced Lung Injury: Benign Inflammation versus Inflammation as a By-product

Dennis Lex, Ph.D., Stefan Uhlig, Ph.D.

Anesthesiology. May 2017: 126(5):909–922

https://doi.org/10.1097/ALN.0000000000001605

Published: May 2017

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Articles

Transient Receptor Potential Vanilloid 4 and Serum Glucocorticoid–regulated Kinase 1 Are Critical Mediators of Lung Injury in Overventilated Mice In Vivo

Laura Michalick, M.Sc., Lasti Erfinanda, M.D., Ulrike Weichelt, Ph.D., Markus van der Giet, M.D., Wolfgang Liedtke, M.D., Ph.D., Wolfgang M. Kuebler, M.D.

Anesthesiology. February 2017: 126(2):300–311

https://doi.org/10.1097/ALN.0000000000001443

Published: February 2017

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Articles

Visualizing the Propagation of Acute Lung Injury

Maurizio Cereda, M.D., Yi Xin, M.S., Natalie Meeder, B.A., Johnathan Zeng, B.S.E., YunQing Jiang, M.S.E., Hooman Hamedani, M.S., Harrilla Profka, D.V.M., Stephen Kadlecek, Ph.D., Justin Clapp, Ph.D., Charuhas G. Deshpande, M.D., Jue Wu, Ph.D., James C. Gee, Ph.D., Brian P. Kavanagh, M.B., Rahim R. Rizi, Ph.D.

Anesthesiology. January 2016: 124(1):121–131

https://doi.org/10.1097/ALN.0000000000000916

Published: January 2016

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Articles

Biological Impact of Transpulmonary Driving Pressure in Experimental Acute Respiratory Distress Syndrome

Cynthia S. Samary, Ph.D., Raquel S. Santos, M.Sc., Ph.D., Cíntia L. Santos, Ph.D., Nathane S. Felix, M.S., Maira Bentes, R.T., Thiago Barboza, M.D., Vera L. Capelozzi, M.D., Ph.D., Marcelo M. Morales, M.D., Ph.D., Cristiane S. N. B. Garcia, Ph.D., Sergio A. L. Souza, Ph.D., John J. Marini, M.D., Marcelo Gama de Abreu, M.D., Ph.D., Pedro L. Silva, Ph.D., Paolo Pelosi, M.D., F.E.R.S., Patricia R. M. Rocco, M.D., Ph.D.

Anesthesiology. August 2015: 123(2):423–433

https://doi.org/10.1097/ALN.0000000000000716

Published: August 2015

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Articles

Isoflurane Ameliorates Acute Lung Injury by Preserving Epithelial Tight Junction Integrity

Joshua A. Englert, M.D., Alvaro A. Macias, M.D., Diana Amador-Munoz, M.D., Miguel Pinilla Vera, M.D., Colleen Isabelle, B.A., Jiazhen Guan, Ph.D., Brady Magaoay, B.A., Margarita Suarez Velandia, M.D., Anna Coronata, B.A., Awapuhi Lee, Laura E. Fredenburgh, M.D., Deborah J. Culley, M.D., Gregory Crosby, M.D., Rebecca M. Baron, M.D.

Anesthesiology. August 2015: 123(2):377–388

https://doi.org/10.1097/ALN.0000000000000742

Published: August 2015

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Articles

Mechanical Ventilation Induces Neutrophil Extracellular Trap Formation

Christopher Yildiz, M.Sc., Nades Palaniyar, M.Sc., Ph.D., Gail Otulakowski, Ph.D., Meraj A. Khan, M.Sc., Ph.D., Martin Post, Ph.D., Wolfgang M. Kuebler, M.D., Keith Tanswell, M.B., M.R.C.P.(U.K.), F.R.C.P.(C.), Rosetta Belcastro, B.Sc., Azhar Masood, M.D., Ph.D., Doreen Engelberts, A.H.T., Brian P. Kavanagh, M.B., M.R.C.P.(I.), F.R.C.P.(C.)

Anesthesiology. April 2015: 122(4):864–875

https://doi.org/10.1097/ALN.0000000000000605

Published: April 2015

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Articles

Therapeutic Efficacy of Human Mesenchymal Stromal Cells in the Repair of Established Ventilator-induced Lung Injury in the Rat

Mairead Hayes, M.D., F.C.A.I., Claire Masterson, Ph.D., James Devaney, Ph.D., Frank Barry, Ph.D., Steve Elliman, Ph.D., Timothy O’Brien, M.D., Ph.D., Daniel O’Toole, Ph.D., Gerard F. Curley, M.B., Ph.D., F.C.A.I., John G. Laffey, M.D., M.A., F.C.A.I.

Anesthesiology. February 2015: 122(2):363–373

https://doi.org/10.1097/ALN.0000000000000545

Published: February 2015

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Articles

A Metabolomic Approach to the Pathogenesis of Ventilator-induced Lung Injury

José L. Izquierdo-García, Ph.D., Shama Naz, B.Sc., Nicolás Nin, M.D., Yeny Rojas, B.Sc., Marcela Erazo, B.Sc., Leticia Martínez-Caro, Ph.D., Antonia García, Ph.D., Marta de Paula, Ph.D., Pilar Fernández-Segoviano, M.D., Cristina Casals, Ph.D., Andrés Esteban, M.D., Jesús Ruíz-Cabello, Ph.D., Coral Barbas, Ph.D., José A. Lorente, M.D.

Anesthesiology. March 2014: 120(3):694–702

https://doi.org/10.1097/ALN.0000000000000074

Published: March 2014

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Articles

Unilateral Acid Aspiration Augments the Effects of Ventilator Lung Injury in the Contralateral Lung

Maria Amigoni, M.D., Giacomo Bellani, M.D., Ph.D., Vanessa Zambelli, Biol.D., Margherita Scanziani, M.D., Francesca Farina, Biol.D,. Ph.D., Lorella Fagnani, M.D., Roberto Latini, M.D., Roberto Fumagalli, M.D., Antonio Pesenti, M.D.

Anesthesiology. September 2013: 119(3):642–651

https://doi.org/10.1097/ALN.0b013e318297d487

Published: September 2013

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NARROW

Lung Injury Is Induced by Abrupt Increase in Respiratory Rate but Prevented by Recruitment Maneuver in Mild Acute Respiratory Distress Syndrome in Rats

Mechanical Power: Correlate or Cause of Ventilator-induced Lung Injury?

Mechanical Power during General Anesthesia and Postoperative Respiratory Failure: A Multicenter Retrospective Cohort Study

Death-associated Protein Kinase 1 Mediates Ventilator-induced Lung Injury in Mice by Promoting Alveolar Epithelial Cell Apoptosis

Does Iso-mechanical Power Lead to Iso-lung Damage?: An Experimental Study in a Porcine Model

Understanding the Mysteries of Mechanical Power

In Memoriam: Brian Kavanagh, 1962 to 2019

Syndecan-2–positive, Bone Marrow–derived Human Mesenchymal Stromal Cells Attenuate Bacterial-induced Acute Lung Injury and Enhance Resolution of Ventilator-induced Lung Injury in Rats

Continuous Negative Abdominal Pressure Reduces Ventilator-induced Lung Injury in a Porcine Model

Energetics and the Root Mechanical Cause for Ventilator-induced Lung Injury

Biologic Impact of Mechanical Power at High and Low Tidal Volumes in Experimental Mild Acute Respiratory Distress Syndrome

One-hit Models of Ventilator-induced Lung Injury: Benign Inflammation versus Inflammation as a By-product

Transient Receptor Potential Vanilloid 4 and Serum Glucocorticoid–regulated Kinase 1 Are Critical Mediators of Lung Injury in Overventilated Mice In Vivo

Visualizing the Propagation of Acute Lung Injury

Biological Impact of Transpulmonary Driving Pressure in Experimental Acute Respiratory Distress Syndrome

Isoflurane Ameliorates Acute Lung Injury by Preserving Epithelial Tight Junction Integrity

Mechanical Ventilation Induces Neutrophil Extracellular Trap Formation

Therapeutic Efficacy of Human Mesenchymal Stromal Cells in the Repair of Established Ventilator-induced Lung Injury in the Rat

A Metabolomic Approach to the Pathogenesis of Ventilator-induced Lung Injury

Unilateral Acid Aspiration Augments the Effects of Ventilator Lung Injury in the Contralateral Lung

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