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Articles

Lidocaine Intraoperative Infusion Pharmacokinetics during Partial Hepatectomy for Living Liver Donation

Cara E. Crouch, M.D., Barbara J. Wilkey, M.D., Adrian Hendrickse, B.M., F.R.C.A., Alexander M. Kaizer, Ph.D., Björn Schniedewind, B.S., Uwe Christians, M.D., Ph.D., Thomas K. Henthorn, M.D., Ana Fernandez-Bustamante, M.D., Ph.D.

Anesthesiology. January 2023: 138(1):71–81

https://doi.org/10.1097/ALN.0000000000004422

Published: January 2023

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Articles

Pharmacotherapy for the Prevention of Chronic Pain after Surgery in Adults: An Updated Systematic Review and Meta-analysis

Meg E. Carley, B.Sc., Luis E. Chaparro, M.D., F.R.C.P.C., Manon Choinière, Ph.D., Henrik Kehlet, M.D., Ph.D., R. Andrew Moore, D.Sc., Elizabeth Van Den Kerkhof, R.N., Dr.PH., Ian Gilron, M.D., M.Sc.

Anesthesiology. August 2021: 135(2):304–325

https://doi.org/10.1097/ALN.0000000000003837

Published: August 2021

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Articles

Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery: A Randomized Controlled Trial

Rebecca Y. Klinger, M.D., M.S., Mary Cooter, M.S., Tiffany Bisanar, B.S., Niccolò Terrando, Ph.D., Miles Berger, M.D., Ph.D., Mihai V. Podgoreanu, M.D., Mark Stafford-Smith, M.D., Mark F. Newman, M.D., Joseph P. Mathew, M.D., M.H.Sc., M.B.A., for the Neurologic Outcomes Research Group of the Duke Heart Center

Anesthesiology. June 2019: 130(6):958–970

https://doi.org/10.1097/ALN.0000000000002668

Published: June 2019

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Articles

Pharmacodynamics and Pharmacokinetics of Lidocaine in a Rodent Model of Diabetic Neuropathy

Werner ten Hoope, M.D., Markus W. Hollmann, M.D., Ph.D., Kora de Bruin, Hein J. Verberne, M.D., Ph.D., Arie O. Verkerk, Ph.D., Hanno L. Tan, M.D., Ph.D., Camiel Verhamme, M.D., Ph.D., Janneke Horn, M.D., Ph.D., Marcel Rigaud, M.D., Susanne Picardi, M.D., Philipp Lirk, M.D., Ph.D.

Anesthesiology. March 2018: 128(3):609–619

https://doi.org/10.1097/ALN.0000000000002035

Published: March 2018

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Articles

Lidocaine Induces Apoptosis and Suppresses Tumor Growth in Human Hepatocellular Carcinoma Cells In Vitro and in a Xenograft Model In Vivo

Wei Xing, M.D., Ph.D., Dong-Tai Chen, M.D., Jia-Hao Pan, M.D., Yong-Hua Chen, M.D., Yan Yan, M.D., Qiang Li, M.D., Rui-Feng Xue, M.D., Yun-Fei Yuan, M.D., Wei-An Zeng, M.D., Ph.D.

Anesthesiology. May 2017: 126(5):868–881

https://doi.org/10.1097/ALN.0000000000001528

Published: May 2017

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Articles

Perioperative Use of Intravenous Lidocaine

Lauren K. Dunn, M.D., Ph.D., Marcel E. Durieux, M.D., Ph.D.

Anesthesiology. April 2017: 126(4):729–737

https://doi.org/10.1097/ALN.0000000000001527

Published: April 2017

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Articles

Opioid-induced Loss of Local Anesthetic Potency in the Rat Sciatic Nerve

Qing Liu, M.D., Ph.D., Michael S. Gold, Ph.D.

Anesthesiology. October 2016: 125(4):755–764

https://doi.org/10.1097/ALN.0000000000001239

Published: October 2016

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Articles

JM25-1, a Lidocaine Analog Combining Airway Relaxant and Antiinflammatory Properties: Implications for New Bronchospasm Therapy

Magda F. Serra, Ph.D., Josiane S. Neves, Ph.D., Gina C. Couto, M.Sc., Amanda C. Cotias, M.Sc., Camila R. Pão, M.Sc., Priscilla C. Olsen, Ph.D., Katharinne I. Moraes de Carvalho, M.Sc., Edna A. Anjos-Valotta, Ph.D., Robson X. Faria, Ph.D., Jorge C. S. Costa, Ph.D., Renato S. B. Cordeiro, Ph.D., Patricia M. R. Silva, Ph.D., Marco A. Martins, Ph.D.

Anesthesiology. January 2016: 124(1):109–120

https://doi.org/10.1097/ALN.0000000000000919

Published: January 2016

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Articles

The Quaternary Lidocaine Derivative, QX-314, Exerts Biphasic Effects on Transient Receptor Potential Vanilloid Subtype 1 Channels In Vitro : Erratum

Anesthesiology. August 2015: 123(2):492

https://doi.org/10.1097/01.anes.0000466954.80399.b8

Published: August 2015

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Articles

Hyperpolarization-activated Cyclic Nucleotide-gated Channels May Contribute to Regional Anesthetic Effects of Lidocaine

Cheng Zhou, Ph.D., Bowen Ke, Ph.D., Yi Zhao, M.B., Peng Liang, M.D., Daqing Liao, M.B., Tao Li, Ph.D., Jin Liu, M.D., Xiangdong Chen, Ph.D., M.D.

Anesthesiology. March 2015: 122(3):606–618

https://doi.org/10.1097/ALN.0000000000000557

Published: March 2015

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Articles

Intraperitoneal Local Anesthetics Have Predominant Local Analgesic Effect: A Randomized, Double-blind Study

Andrea Perniola, M.D., Ph.D., Anders Magnuson, B.Sc., Kjell Axelsson, M.D., Ph.D., Anil Gupta, F.R.C.A., M.D., Ph.D.

Anesthesiology. August 2014: 121(2):352–361

https://doi.org/10.1097/ALN.0000000000000267

Published: August 2014

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Articles

Endothelial Barrier Protection by Local Anesthetics: Ropivacaine and Lidocaine Block Tumor Necrosis Factor-α–induced Endothelial Cell Src Activation

Tobias Piegeler, M.D., E. Gina Votta-Velis, M.D., Ph.D., Farnaz R. Bakhshi, Ph.D., Mao Mao, M.S., Graeme Carnegie, Ph.D., Marcelo G. Bonini, Ph.D., David E. Schwartz, M.D., Alain Borgeat, M.D., Beatrice Beck-Schimmer, M.D., Richard D. Minshall, Ph.D.

Anesthesiology. June 2014: 120(6):1414–1428

https://doi.org/10.1097/ALN.0000000000000174

Published: June 2014

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Articles

Nociceptor-selective Peripheral Nerve Block Induces Delayed Mechanical Hypersensitivity and Neurotoxicity in Rats

Christopher M. Peters, Ph.D., Douglas Ririe, M.D., Ph.D., Timothy T. Houle, Ph.D., Carol A. Aschenbrenner, M.A., James C. Eisenach, M.D.

Anesthesiology. April 2014: 120(4):976–986

https://doi.org/10.1097/ALN.0000000000000088

Published: April 2014

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Articles

Despite Differences in Cytosolic Calcium Regulation, Lidocaine Toxicity Is Similar in Adult and Neonatal Rat Dorsal Root Ganglia In Vitro

Lisa V. Doan, M.D., Olga Eydlin, M.D., Boris Piskoun, B.A., Richard P. Kline, Ph.D., Esperanza Recio-Pinto, Ph.D., Andrew D. Rosenberg, M.D., Thomas J. J. Blanck, M.D., Ph.D., Fang Xu, Ph.D.

Anesthesiology. January 2014: 120(1):50–61

https://doi.org/10.1097/ALN.0b013e3182a2a561

Published: January 2014

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Articles

Lidocaine Patch (5%) in Treatment of Persistent Inguinal Postherniorrhaphy Pain: A Randomized, Double-blind, Placebo-controlled, Crossover Trial

Joakim M. Bischoff, M.D., Marian Petersen, Ph.D., Nurcan Üçeyler, M.D., Claudia Sommer, M.D., Henrik Kehlet, M.D., D.M.Sc., Mads U. Werner, M.D., D.M.Sc.

Anesthesiology. December 2013: 119(6):1444–1452

https://doi.org/10.1097/ALN.0b013e3182a2a243

Published: December 2013

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Articles

Effect of Perioperative Intravenous Lidocaine Administration on Pain, Opioid Consumption, and Quality of Life after Complex Spine Surgery

Ehab Farag, M.D., F.R.C.A., Michael Ghobrial, M.D., Daniel I. Sessler, M.D., Jarrod E. Dalton, Ph.D., Jinbo Liu, M.D., Jae H. Lee, B.A., Sherif Zaky, M.D., Edward Benzel, M.D., William Bingaman, M.D., Andrea Kurz, M.D.

Anesthesiology. October 2013: 119(4):932–940

https://doi.org/10.1097/ALN.0b013e318297d4a5

Published: October 2013

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Articles

Nebulized Lidocaine Prevents Airway Inflammation, Peribronchial Fibrosis, and Mucus Production in a Murine Model of Asthma

Magda F. Serra, Ph.D., Edna A. Anjos-Valotta, Ph.D., Priscilla C. Olsen, Ph.D., Gina C. Couto, B.Sc., Patricia B. Jurgilas, Ph.D., Amanda C. Cotias, B.Sc., Camila R. Pão, B.Sc., Tatiana P. T. Ferreira, Ph.D., Ana C. S. Arantes, M.Sc., Ana L. A. Pires, M.Sc., Renato S. B. Cordeiro, Ph.D., Patricia M. R. Silva, Ph.D., Marco A. Martins, Ph.D.

Anesthesiology. September 2012: 117(3):580–591

https://doi.org/10.1097/ALN.0b013e31826687d5

Published: September 2012

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Articles

Antimetastatic Potential of Amide-linked Local Anesthetics: Inhibition of Lung Adenocarcinoma Cell Migration and Inflammatory Src Signaling Independent of Sodium Channel Blockade

Tobias Piegeler, M.D., E. Gina Votta-Velis, M.D., Ph.D., Guoquan Liu, Ph.D., Aaron T. Place, Ph.D., David E. Schwartz, M.D., Beatrice Beck-Schimmer, M.D., Richard D. Minshall, Ph.D., Alain Borgeat, M.D.

Anesthesiology. September 2012: 117(3):548–559

https://doi.org/10.1097/ALN.0b013e3182661977

Published: September 2012

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Articles

Anesthesia Literature Review

Jean Mantz, M.D., Ph.D.

Anesthesiology. June 2012: 116(6):1364–1366

https://doi.org/10.1097/ALN.0b013e318256e31f

Published: June 2012

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Articles

Lidocaine Metabolites Inhibit Glycine Transporter 1: A Novel Mechanism for the Analgesic Action of Systemic Lidocaine?

Robert Werdehausen, M.D., David Kremer, M.D., Timo Brandenburger, M.D., Lukas Schlösser, M.D., Janusz Jadasz, M.Sc., Patrick Küry, Ph.D., Inge Bauer, Ph.D., Carmen Aragón, Ph.D., Volker Eulenburg, Ph.D., Henning Hermanns, M.D.

Anesthesiology. January 2012: 116(1):147–158

https://doi.org/10.1097/ALN.0b013e31823cf233

Published: January 2012

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NARROW

Lidocaine Intraoperative Infusion Pharmacokinetics during Partial Hepatectomy for Living Liver Donation

Pharmacotherapy for the Prevention of Chronic Pain after Surgery in Adults: An Updated Systematic Review and Meta-analysis

Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery: A Randomized Controlled Trial

Pharmacodynamics and Pharmacokinetics of Lidocaine in a Rodent Model of Diabetic Neuropathy

Lidocaine Induces Apoptosis and Suppresses Tumor Growth in Human Hepatocellular Carcinoma Cells In Vitro and in a Xenograft Model In Vivo

Perioperative Use of Intravenous Lidocaine

Opioid-induced Loss of Local Anesthetic Potency in the Rat Sciatic Nerve

JM25-1, a Lidocaine Analog Combining Airway Relaxant and Antiinflammatory Properties: Implications for New Bronchospasm Therapy

The Quaternary Lidocaine Derivative, QX-314, Exerts Biphasic Effects on Transient Receptor Potential Vanilloid Subtype 1 Channels In Vitro : Erratum

Hyperpolarization-activated Cyclic Nucleotide-gated Channels May Contribute to Regional Anesthetic Effects of Lidocaine

Intraperitoneal Local Anesthetics Have Predominant Local Analgesic Effect: A Randomized, Double-blind Study

Endothelial Barrier Protection by Local Anesthetics: Ropivacaine and Lidocaine Block Tumor Necrosis Factor-α–induced Endothelial Cell Src Activation

Nociceptor-selective Peripheral Nerve Block Induces Delayed Mechanical Hypersensitivity and Neurotoxicity in Rats

Despite Differences in Cytosolic Calcium Regulation, Lidocaine Toxicity Is Similar in Adult and Neonatal Rat Dorsal Root Ganglia In Vitro

Lidocaine Patch (5%) in Treatment of Persistent Inguinal Postherniorrhaphy Pain: A Randomized, Double-blind, Placebo-controlled, Crossover Trial

Effect of Perioperative Intravenous Lidocaine Administration on Pain, Opioid Consumption, and Quality of Life after Complex Spine Surgery

Nebulized Lidocaine Prevents Airway Inflammation, Peribronchial Fibrosis, and Mucus Production in a Murine Model of Asthma

Antimetastatic Potential of Amide-linked Local Anesthetics: Inhibition of Lung Adenocarcinoma Cell Migration and Inflammatory Src Signaling Independent of Sodium Channel Blockade

Anesthesia Literature Review

Lidocaine Metabolites Inhibit Glycine Transporter 1: A Novel Mechanism for the Analgesic Action of Systemic Lidocaine?

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