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Patient-, Clinician-, and Institution-level Variation in Inotrope Use for Cardiac Surgery: A Multicenter Observational Analysis

Michael R. Mathis, M.D., Allison M. Janda, M.D., Sachin Kheterpal, M.D., M.B.A., Robert B. Schonberger, M.D., M.H.S., Francis D. Pagani, M.D., Ph.D., Milo C. Engoren, M.D., Graciela B. Mentz, Ph.D., Douglas C. Shook, M.D., Jochen D. Muehlschlegel, M.D., M.Sc., M.B.A., Multicenter Perioperative Outcomes Group, Ruth Cassidy, Ph.D., David J. Clark, M.D., Ph.D., Douglas A. Colquhoun, M.B.Ch.B., M.Sc., M.P.H., Robert E. Freundlich, M.D., M.Sc., Elizabeth S. Jewell, M.S.

Anesthesiology. August 2023: 139(2):122–141

https://doi.org/10.1097/ALN.0000000000004593

Published: August 2023

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Articles

Intraoperative Hypotension and Acute Kidney Injury, Stroke, and Mortality during and outside Cardiopulmonary Bypass: A Retrospective Observational Cohort Study

Miguel Armengol de la Hoz, M.S., Valluvan Rangasamy, M.D., D.N.B., D.E.S.A., Andres Brenes Bastos, M.D., Xinling Xu, Ph.D., Victor Novack, M.D., Bernd Saugel, M.D., Balachundhar Subramaniam, M.D., M.P.H., F.A.S.A.

Anesthesiology. June 2022: 136(6):927–939

https://doi.org/10.1097/ALN.0000000000004175

Published: June 2022

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Articles

In Vitro Negative Inotropic Effect of Low Concentrations of Bupivacaine Relates to Diminished Ca 2+ Sensitivity but Not to Ca 2+ Handling or β-Adrenoceptor Signaling

Frederik Flenner, Ph.D., Nicole Arlt, Ph.D., Mahtab Nasib, cand.med., Sophie Schobesberger, Ph.D., Thea Koch, M.D., Ursula Ravens, M.D., Felix Friedrich, M.D., Viacheslav Nikolaev, Ph.D., Torsten Christ, M.D., Sebastian N. Stehr, M.D.

Anesthesiology. June 2018: 128(6):1175–1186

https://doi.org/10.1097/ALN.0000000000002180

Published: June 2018

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Articles

Overexpression of Cyclic Adenosine Monophosphate Effluent Protein MRP4 Induces an Altered Response to β-Adrenergic Stimulation in the Senescent Rat Heart

Aude Carillion, M.D., Sarah Feldman, Cheng Jiang, M.D., Fabrice Atassi, Ph.D., Na Na, M.D., Nathalie Mougenot, Sophie Besse, Ph.D., Jean-Sébastien Hulot, M.D., Ph.D., Bruno Riou, M.D., Ph.D., Julien Amour, M.D., Ph.D.

Anesthesiology. February 2015: 122(2):334–342

https://doi.org/10.1097/ALN.0000000000000526

Published: February 2015

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Articles

Complex Information for Anesthesiologists Presented Quickly and Clearly: Vasopressor Variation: Intra- and International Variation in Perioperative Utilization of Vasopressors and Inotropes in Cardiac Surgery

Anesthesiology. May 2014: 120(5):A29

https://doi.org/10.1097/01.anes.0000446481.19647.82

Published: May 2014

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Articles

Health Outcomes with and without Use of Inotropic Therapy in Cardiac Surgery: Results of a Propensity Score–matched Analysis

Dorthe Viemose Nielsen, M.D., Malene Kærslund Hansen, M.B.B.S., Søren Paaske Johnsen, M.D., Ph.D., Mads Hansen, M.D., Karsten Hindsholm, M.D., H.D., Carl-Johan Jakobsen, M.D.

Anesthesiology. May 2014: 120(5):1098–1108

https://doi.org/10.1097/ALN.0000000000000224

Published: May 2014

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Articles

Less Is More: A Superior Clinical Strategy?

Sachin Kheterpal, M.D., M.B.A., Jean-Luc Fellahi, M.D., Ph.D.

Anesthesiology. May 2014: 120(5):1067–1068

https://doi.org/10.1097/ALN.0000000000000225

Published: May 2014

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Articles

Positive Inotropic Agents in Myocardial Ischemia–Reperfusion Injury: A Benefit/Risk Analysis

Jean-Luc Fellahi, M.D., Ph.D., Marc-Olivier Fischer, M.D., Georges Daccache, M.D., Jean-Louis Gerard, M.D., Jean-Luc Hanouz, M.D., Ph.D.

Anesthesiology. June 2013: 118(6):1460–1465

https://doi.org/10.1097/ALN.0b013e31828f4fc3

Published: June 2013

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Articles

Interaction of Metabolic and Respiratory Acidosis with α and β-adrenoceptor Stimulation in Rat Myocardium

Matthieu Biais, M.D., Romain Jouffroy, M.D., Aude Carillion, M.D., Sarah Feldman, Aude Jobart-Malfait, B.S., Bruno Riou, M.D., Ph.D., Julien Amour, M.D., Ph.D.

Anesthesiology. December 2012: 117(6):1212–1222

https://doi.org/10.1097/ALN.0b013e3182753264

Published: December 2012

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Articles

Myocardial Effects of Halothane and Isoflurane in Senescent Rats

Sandrine Rozenberg, M.D., Sophie Besse, Ph.D., Benoît Vivien, M.D., Pierre Coriat, M.D., Bruno Riou, M.D., Ph.D.

Anesthesiology. December 2002: 97(6):1477–1484

https://doi.org/10.1097/00000542-200212000-00020

Published: December 2002

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Articles

Negative and Positive Inotropic Effects of Propofol via L-type Calcium Channels and the Sodium-Calcium Exchanger in Rat Cardiac Trabeculae

Wouter de Ruijter, M.D., Ger J. M. Stienen, Ph.D., Jan van Klarenbosch, M.D., Jacob J. de Lange, M.D., Ph.D.

Anesthesiology. November 2002: 97(5):1146–1155

https://doi.org/10.1097/00000542-200211000-00019

Published: November 2002

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Articles

Xenon Does Not Impair the Responsiveness of Cardiac Muscle Bundles to Positive Inotropic and Chronotropic Stimulation

Sylvia C. Schroth, M.D., Ulrich Schotten, M.D., Orkide Alkanoglu, Matthias S. Reyle-Hahn, M.D., Peter Hanrath, M.D., Rolf Rossaint, M.D.

Anesthesiology. February 2002: 96(2):422–427

https://doi.org/10.1097/00000542-200202000-00030

Published: February 2002

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Articles

Effect of Volatile Anesthetics on the Force–Frequency Relation in Human Ventricular Myocardium: The Role of the Sarcoplasmic Reticulum Calcium-release Channel

Ulrich Schotten, M.D., Maura Greiser, M.D., Volker Braun, Christian Karlein, Friedrich Schoendube, M.D., Peter Hanrath, M.D.

Anesthesiology. November 2001: 95(5):1160–1168

https://doi.org/10.1097/00000542-200111000-00020

Published: November 2001

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Articles

Interaction of Protamine with α- and β-Adrenoceptor Stimulations in Rat Myocardium

Jean-Stéphane David, M.D., Benoît Vivien, M.D., Yves Lecarpentier, M.D., Ph.D., Pierre Coriat, M.D., Bruno Riou, M.D., Ph.D.

Anesthesiology. November 2001: 95(5):1226–1233

https://doi.org/10.1097/00000542-200111000-00029

Published: November 2001

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Articles

Effects of Dantrolene on Rat Diaphragm Muscle during Postnatal Maturation

Gilles Orliaguet, M.D., Olivier Langeron, M.D., Catherine Coirault, M.D., Ph.D., Sylvia Fratea, M.D., Pierre Coriat, M.D., Bruno Riou, M.D., Ph.D.

Anesthesiology. March 2001: 94(3):468–474

https://doi.org/10.1097/00000542-200103000-00018

Published: March 2001

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Articles

Impairment of Cardiac β-Adrenoceptor Cellular Signaling by Decreased Expression of G sα in Septic Rabbits

Naoyuki Matsuda, M.D., Yuichi Hattori, M.D., Ph.D., Yasuhiro Akaishi, M.D., Ph.D., Yukari Suzuki, M.D., Osamu Kemmotsu, M.D., Ph.D., Satoshi Gando, M.D., Ph.D.

Anesthesiology. December 2000: 93(6):1465–1473

https://doi.org/10.1097/00000542-200012000-00019

Published: December 2000

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Articles

Room D, 10/16/2000 2: 00 PM - 4: 00 PM (PS) Inotropic and Electrophysiologic Effects of Azumolene Sodium in Ventricular Myocardium : A-647

In Vitro Wyun Kon Park, MD, Ki Jun Kim, MD

Anesthesiology. September 2000: 93(3A):A–647

https://doi.org/10.1097/00000542-200009001-00647

Published: September 2000

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Articles

Anesthesiology Pocket Guide.

James C. Eisenach, M.D., Leanne Groban, M.D.

Anesthesiology. January 2000: 92(1):294

https://doi.org/10.1097/00000542-200001000-00062

Published: January 2000

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Articles

In Vitro Effects of Desflurane, Sevoflurane, Isoflurane, and Halothane in Isolated Human Right Atria

Jean-Luc Hanouz, M.D., Massimo Massetti, M.D., Géraldine Guesne, B.Sc., Stéphane Chanel, M.D., Gérard Babatasi, M.D., Ph.D., René Rouet, Ph.D., Pierre Ducouret, Ph.D., André Khayat, M.D., M.D., Françoise Galateau, M.D., Henri Bricard, M.D., Jean-Louis Gérard, M.D., Ph.D.

Anesthesiology. January 2000: 92(1):116

https://doi.org/10.1097/00000542-200001000-00022

Published: January 2000

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Articles

Interaction of Halogenated Anesthetics with Dobutamine in Rat Myocardium

Pierre-Yves Gueugniaud, MD, PhD, Jean-Luc Hanouz, MD, Jean-Marc Martino, MD, Yves Lecarpentier, MD, PhD, Pierre Coriat, MD, Bruno Riou, MD, PhD

Anesthesiology. June 1999: 90(6):1663–1670.

https://doi.org/10.1097/00000542-199906000-00023

Published: June 1999

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NARROW

Patient-, Clinician-, and Institution-level Variation in Inotrope Use for Cardiac Surgery: A Multicenter Observational Analysis

Intraoperative Hypotension and Acute Kidney Injury, Stroke, and Mortality during and outside Cardiopulmonary Bypass: A Retrospective Observational Cohort Study

In Vitro Negative Inotropic Effect of Low Concentrations of Bupivacaine Relates to Diminished Ca 2+ Sensitivity but Not to Ca 2+ Handling or β-Adrenoceptor Signaling

Overexpression of Cyclic Adenosine Monophosphate Effluent Protein MRP4 Induces an Altered Response to β-Adrenergic Stimulation in the Senescent Rat Heart

Complex Information for Anesthesiologists Presented Quickly and Clearly: Vasopressor Variation: Intra- and International Variation in Perioperative Utilization of Vasopressors and Inotropes in Cardiac Surgery

Health Outcomes with and without Use of Inotropic Therapy in Cardiac Surgery: Results of a Propensity Score–matched Analysis

Less Is More: A Superior Clinical Strategy?

Positive Inotropic Agents in Myocardial Ischemia–Reperfusion Injury: A Benefit/Risk Analysis

Interaction of Metabolic and Respiratory Acidosis with α and β-adrenoceptor Stimulation in Rat Myocardium

Myocardial Effects of Halothane and Isoflurane in Senescent Rats

Negative and Positive Inotropic Effects of Propofol via L-type Calcium Channels and the Sodium-Calcium Exchanger in Rat Cardiac Trabeculae

Xenon Does Not Impair the Responsiveness of Cardiac Muscle Bundles to Positive Inotropic and Chronotropic Stimulation

Effect of Volatile Anesthetics on the Force–Frequency Relation in Human Ventricular Myocardium: The Role of the Sarcoplasmic Reticulum Calcium-release Channel

Interaction of Protamine with α- and β-Adrenoceptor Stimulations in Rat Myocardium

Effects of Dantrolene on Rat Diaphragm Muscle during Postnatal Maturation

Impairment of Cardiac β-Adrenoceptor Cellular Signaling by Decreased Expression of G sα in Septic Rabbits

Room D, 10/16/2000 2: 00 PM - 4: 00 PM (PS) Inotropic and Electrophysiologic Effects of Azumolene Sodium in Ventricular Myocardium : A-647

Anesthesiology Pocket Guide.

In Vitro Effects of Desflurane, Sevoflurane, Isoflurane, and Halothane in Isolated Human Right Atria

Interaction of Halogenated Anesthetics with Dobutamine in Rat Myocardium

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