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Articles

Association of Genetic Variants with Postsurgical Pain: A Systematic Review and Meta-analyses

Stephan G. Frangakis, M.D., Ph.D., Mark MacEachern, M.L.I.S., T. Adam Akbar, M.D., Christian Bolton, M.D., Victor Lin, D.O., Ph.D., Albert V. Smith, Ph.D., Chad M. Brummett, M.D., Mark C. Bicket, M.D., Ph.D.

Anesthesiology. December 2023: 139(6):827–839

https://doi.org/10.1097/ALN.0000000000004677

Published: December 2023

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Articles

Single-nucleus Atlas of Sevoflurane-induced Hippocampal Cell Type– and Sex-specific Effects during Development in Mice

Shao-yong Song, M.D., Ph.D., Ke Peng, M.D., Ph.D., Xiao-wen Meng, Ph.D., Xi-sheng Shan, M.D., Ph.D., Qing-cai Chen, M.D., Wei-ming Zhao, M.D., Biyu Shen, M.D., Hong Qiu, Ph.D., Hong Liu, M.D., FASE, Hua-yue Liu, M.D., Fu-hai Ji, M.D., Ph.D.

Anesthesiology. May 2023: 138(5):477–495

https://doi.org/10.1097/ALN.0000000000004522

Published: May 2023

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Articles

Lung Atelectasis Promotes Immune and Barrier Dysfunction as Revealed by Transcriptome Sequencing in Female Sheep

Congli Zeng, M.D., Ph.D., Gabriel C. Motta-Ribeiro, Ph.D., Takuga Hinoshita, M.D., Ph.D., Marcos Adriano Lessa, M.D., Ph.D., Tilo Winkler, Ph.D., Kira Grogg, Ph.D., Nathan M. Kingston, B.S., John N. Hutchinson, Ph.D., Lynette Marie Sholl, M.D., Xiangming Fang, M.D., Ph.D., Xaralabos Varelas, Ph.D., Matthew D. Layne, Ph.D., Rebecca M. Baron, M.D., Marcos F. Vidal Melo, M.D., Ph.D.

Anesthesiology. November 2020: 133(5):1060–1076

https://doi.org/10.1097/ALN.0000000000003491

Published: November 2020

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Articles

Genetic Analysis of Patients Who Experienced Awareness with Recall while under General Anesthesia

Jamie W. Sleigh, M.D., Kate Leslie, M.D., Andrew J. Davidson, M.D., David J. Amor, Ph.D., Peter Diakumis, M.Bioinf., Vesna Lukic, M.Sci., Paul J. Lockhart, Ph.D., Melanie Bahlo, Ph.D.

Anesthesiology. November 2019: 131(5):974–982

https://doi.org/10.1097/ALN.0000000000002877

Published: November 2019

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Articles

Be Wary of Genes Governing Awareness

Philip G. Morgan, M.D., Max B. Kelz, M.D., Ph.D.

Anesthesiology. November 2019: 131(5):955–956

https://doi.org/10.1097/ALN.0000000000002886

Published: November 2019

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Articles

Sphingosine-1-phosphate Receptor 2 Signaling Promotes Caspase-11–dependent Macrophage Pyroptosis and Worsens Escherichia coli Sepsis Outcome

Fang Song, M.Sc., Jinchao Hou, Ph.D., Zhecong Chen, M.Sc., Baoli Cheng, Ph.D., Ruyi Lei, M.Sc., Ping Cui, M.Sc., Yaqi Sun, M.Sc., Haihong Wang, Ph.D., Xiangming Fang, M.D.

Anesthesiology. August 2018: 129(2):311–320

https://doi.org/10.1097/ALN.0000000000002196

Published: August 2018

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Articles

Astrocytic N-Myc Downstream-regulated Gene–2 Is Involved in Nuclear Transcription Factor κB–mediated Inflammation Induced by Global Cerebral Ischemia

You-liang Deng, M.D., Yu-long Ma, Ph.D., Zeng-li Zhang, M.D., Li-xia Zhang, M.D., Hang Guo, Ph.D., Pei Qin, M.D., Yu-shu Hou, M.D., Zi-jun Gao, M.D., Wu-gang Hou, Ph.D.

Anesthesiology. March 2018: 128(3):574–586

https://doi.org/10.1097/ALN.0000000000002044

Published: March 2018

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Articles

Transcriptional Changes in Dorsal Spinal Cord Persist after Surgical Incision Despite Preemptive Analgesia with Peripheral Resiniferatoxin

Stephen J. Raithel, B.A., Matthew R. Sapio, Ph.D., Danielle M. LaPaglia, B.A., Michael J. Iadarola, Ph.D., Andrew J. Mannes, M.D.

Anesthesiology. March 2018: 128(3):620–635

https://doi.org/10.1097/ALN.0000000000002006

Published: March 2018

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Articles

Targeted Genotyping Identifies Susceptibility Locus in Brain-derived Neurotrophic Factor Gene for Chronic Postsurgical Pain

Anesthesiology. March 2018: 128(3):587–597

https://doi.org/10.1097/ALN.0000000000001977

Published: March 2018

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Articles

Malignant Hyperthermia in the Post-Genomics Era: New Perspectives on an Old Concept

Sheila Riazi, M.Sc., M.D., Natalia Kraeva, Ph.D., Philip M. Hopkins, M.D., F.R.C.A.

Anesthesiology. January 2018: 128(1):168–180

https://doi.org/10.1097/ALN.0000000000001878

Published: January 2018

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Articles

Growth Arrest and DNA-damage–inducible Protein 45β-mediated DNA Demethylation of Voltage-dependent T-type Calcium Channel 3.2 Subunit Enhances Neuropathic Allodynia after Nerve Injury in Rats

Cheng-Yuan Lai, B.S., Ming-Chun Hsieh, M.Sc., Yu-Cheng Ho, Ph.D., An-Sheng Lee, Ph.D., Hsueh-Hsiao Wang, Ph.D., Jen-Kun Cheng, M.D., Ph.D., Yat-Pang Chau, Ph.D., Hsien-Yu Peng, Ph.D.

Anesthesiology. June 2017: 126(6):1077–1095

https://doi.org/10.1097/ALN.0000000000001610

Published: June 2017

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Articles

Up-regulation of Cathepsin G in the Development of Chronic Postsurgical Pain: An Experimental and Clinical Genetic Study

Xiaodong Liu, B.Sc., M.Eng., Ph.D., Yuanyuan Tian, B.Med., M.Med., Ph.D., Zhaoyu Meng, B.Sc., M.Phil., Ph.D., Yan Chen, B.Sc., M.Sc., Ph.D., Idy H. T. Ho, B.Sc., Kwong Wai Choy, B.Sc., M.Sc., Ph.D., Peter Lichtner, Ph.D., Sunny H. Wong, M.B.Ch.B., D.Phil., M.R.C.P., Jun Yu, M.D., Ph.D., Tony Gin, M.D., F.R.C.A., F.A.N.Z.C.A., F.H.K.C.A., William K. K. Wu, M.Phil., Ph.D., F.R.C.Path., Christopher H. K. Cheng, B.Sc., Ph.D., Matthew T. V. Chan, M.B.B.S., Ph.D., F.A.N.Z.C.A., F.H.K.C.A.

Anesthesiology. October 2015: 123(4):838–850

https://doi.org/10.1097/ALN.0000000000000828

Published: October 2015

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Articles

MicroRNA-21 Mediates Isoflurane-induced Cardioprotection against Ischemia–Reperfusion Injury via Akt/Nitric Oxide Synthase/Mitochondrial Permeability Transition Pore Pathway

Shigang Qiao, M.D., Jessica M. Olson, Ph.D., Mark Paterson, B.S., Yasheng Yan, B.S., Ivan Zaja, B.S., Yanan Liu, Ph.D., Matthias L. Riess, M.D., Ph.D., Judy R. Kersten, M.D., Mingyu Liang, Ph.D., David C. Warltier, M.D., Ph.D., Zeljko J. Bosnjak, Ph.D., Zhi-Dong Ge, M.D., Ph.D.

Anesthesiology. October 2015: 123(4):786–798

https://doi.org/10.1097/ALN.0000000000000807

Published: October 2015

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Articles

Using Next-generation RNA Sequencing to Examine Ischemic Changes Induced by Cold Blood Cardioplegia on the Human Left Ventricular Myocardium Transcriptome

Jochen D. Muehlschlegel, M.D., M.M.Sc., Danos C. Christodoulou, Ph.D., David McKean, Ph.D., Joshua Gorham, B.A., Erica Mazaika, B.S., M.S., Mahyar Heydarpour, Ph.D., Grace Lee, M.D., Steven R. DePalma, Ph.D., Tjorvi E. Perry, M.D., M.M.Sc., Amanda A. Fox, M.D., M.P.H., Stanton K. Shernan, M.D., Christine E. Seidman, M.D., Sary F. Aranki, M.D., Jon G. Seidman, Ph.D., Simon C. Body, M.B.Ch.B., M.P.H.

Anesthesiology. March 2015: 122(3):537–550

https://doi.org/10.1097/ALN.0000000000000582

Published: March 2015

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Articles

OPRM1 A118G Gene Variant and Postoperative Opioid Requirement: A Systematic Review and Meta-analysis

In Cheol Hwang, M.D., Ph.D., Ji-Young Park, M.D., Ph.D., Seung-Kwon Myung, M.D., Ph.D., Hong Yup Ahn, Ph.D., Ken-ichi Fukuda, M.D., Ph.D., Qin Liao, M.D., Ph.D.

Anesthesiology. October 2014: 121(4):825–834

https://doi.org/10.1097/ALN.0000000000000405

Published: October 2014

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Articles

Letting the Gene out of the Bottle: OPRM1 Interactions

Inna Belfer, M.D., Ph.D., Erin E. Young, Ph.D., Luda Diatchenko, M.D., Ph.D.

Anesthesiology. October 2014: 121(4):678–680

https://doi.org/10.1097/ALN.0000000000000404

Published: October 2014

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Articles

Inhibition of N-myc Downstream–regulated Gene-2 Is Involved in an Astrocyte-specific Neuroprotection Induced by Sevoflurane Preconditioning

Xin Li, M.D., Peng Luo, M.D., Ph.D., Feng Wang, M.D., Ph.D., Qianzi Yang, M.D., Ph.D., Yan Li, M.D., Ph.D., Mingming Zhao, M.D., Shiquan Wang, M.S., Qiang Wang, M.D., Ph.D., Lize Xiong, M.D., Ph.D.

Anesthesiology. September 2014: 121(3):549–562

https://doi.org/10.1097/ALN.0000000000000314

Published: September 2014

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Articles

Noncoding RNAs: New Players in Chronic Pain

Brianna Marie Lutz, B.S., Alex Bekker, M.D., Ph.D., Yuan-Xiang Tao, M.D., Ph.D.

Anesthesiology. August 2014: 121(2):409–417

https://doi.org/10.1097/ALN.0000000000000265

Published: August 2014

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Articles

GNAS Gene Variants Affect β-blocker–related Survival after Coronary Artery Bypass Grafting

Ulrich H. Frey, M.D., Jochen D. Muehlschlegel, M.D., M.M.Sc., Christoph Ochterbeck, Ph.D., Amanda A. Fox, M.D., M.P.H., Stanton K. Shernan, M.D., Charles D. Collard, M.D., Peter Lichtner, Ph.D., Jürgen Peters, M.D., Simon Body, M.B.Ch.B., M.P.H.

Anesthesiology. May 2014: 120(5):1109–1117

https://doi.org/10.1097/ALN.0000000000000189

Published: May 2014

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Articles

Effect of Catechol-o-methyltransferase-gene ( COMT ) Variants on Experimental and Acute Postoperative Pain in 1,000 Women undergoing Surgery for Breast Cancer

Oleg Kambur, M.Sc.(Pharm.), Mari A. Kaunisto, Ph.D., Emmi Tikkanen, M.Sc., Suzanne M. Leal, Ph.D., Samuli Ripatti, Ph.D., Eija A. Kalso, M.D., Ph.D.

Anesthesiology. December 2013: 119(6):1422–1433

https://doi.org/10.1097/ALN.0000000000000013

Published: December 2013

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NARROW

Association of Genetic Variants with Postsurgical Pain: A Systematic Review and Meta-analyses

Single-nucleus Atlas of Sevoflurane-induced Hippocampal Cell Type– and Sex-specific Effects during Development in Mice

Lung Atelectasis Promotes Immune and Barrier Dysfunction as Revealed by Transcriptome Sequencing in Female Sheep

Genetic Analysis of Patients Who Experienced Awareness with Recall while under General Anesthesia

Be Wary of Genes Governing Awareness

Sphingosine-1-phosphate Receptor 2 Signaling Promotes Caspase-11–dependent Macrophage Pyroptosis and Worsens Escherichia coli Sepsis Outcome

Astrocytic N-Myc Downstream-regulated Gene–2 Is Involved in Nuclear Transcription Factor κB–mediated Inflammation Induced by Global Cerebral Ischemia

Transcriptional Changes in Dorsal Spinal Cord Persist after Surgical Incision Despite Preemptive Analgesia with Peripheral Resiniferatoxin

Targeted Genotyping Identifies Susceptibility Locus in Brain-derived Neurotrophic Factor Gene for Chronic Postsurgical Pain

Malignant Hyperthermia in the Post-Genomics Era: New Perspectives on an Old Concept

Growth Arrest and DNA-damage–inducible Protein 45β-mediated DNA Demethylation of Voltage-dependent T-type Calcium Channel 3.2 Subunit Enhances Neuropathic Allodynia after Nerve Injury in Rats

Up-regulation of Cathepsin G in the Development of Chronic Postsurgical Pain: An Experimental and Clinical Genetic Study

MicroRNA-21 Mediates Isoflurane-induced Cardioprotection against Ischemia–Reperfusion Injury via Akt/Nitric Oxide Synthase/Mitochondrial Permeability Transition Pore Pathway

Using Next-generation RNA Sequencing to Examine Ischemic Changes Induced by Cold Blood Cardioplegia on the Human Left Ventricular Myocardium Transcriptome

OPRM1 A118G Gene Variant and Postoperative Opioid Requirement: A Systematic Review and Meta-analysis

Letting the Gene out of the Bottle: OPRM1 Interactions

Inhibition of N-myc Downstream–regulated Gene-2 Is Involved in an Astrocyte-specific Neuroprotection Induced by Sevoflurane Preconditioning

Noncoding RNAs: New Players in Chronic Pain

GNAS Gene Variants Affect β-blocker–related Survival after Coronary Artery Bypass Grafting

Effect of Catechol-o-methyltransferase-gene ( COMT ) Variants on Experimental and Acute Postoperative Pain in 1,000 Women undergoing Surgery for Breast Cancer

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