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Pharmacotherapy for the Prevention of Chronic Pain after Surgery in Adults: An Updated Systematic Review and Meta-analysis

Meg E. Carley, B.Sc., Luis E. Chaparro, M.D., F.R.C.P.C., Manon Choinière, Ph.D., Henrik Kehlet, M.D., Ph.D., R. Andrew Moore, D.Sc., Elizabeth Van Den Kerkhof, R.N., Dr.PH., Ian Gilron, M.D., M.Sc.

Anesthesiology. August 2021: 135(2):304–325

https://doi.org/10.1097/ALN.0000000000003837

Published: August 2021

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Articles

Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis

Michael Verret, M.D., M.Sc., François Lauzier, M.D., M.Sc., Ryan Zarychanski, M.D.,M.Sc., Caroline Perron, M.Sc., Xavier Savard, M.D. candidate, Anne-Marie Pinard, M.D., M.Sc., Guillaume Leblanc, M.D., M.Sc., Marie-Joëlle Cossi, Ph.D., Xavier Neveu, M.Sc., Alexis F. Turgeon, M.D., M.Sc., the Canadian Perioperative Anesthesia Clinical Trials (PACT) Group

Anesthesiology. August 2020: 133(2):265–279

https://doi.org/10.1097/ALN.0000000000003428

Published: August 2020

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Articles

Multimodal Analgesic Regimen for Spine Surgery: A Randomized Placebo-controlled Trial

Kamal Maheshwari, M.D., M.P.H., Rafi Avitsian, M.D., F.A.S.A., Daniel I. Sessler, M.D., Natalya Makarova, M.S., Marianne Tanios, M.D., M.P.H., Syed Raza, B.S., David Traul, M.D., Shobana Rajan, M.D., Mariel Manlapaz, M.D., Sandra Machado, M.D., Ajit Krishnaney, M.D., Andre Machado, M.D., Richard Rosenquist, M.D., Andrea Kurz, M.D.

Anesthesiology. May 2020: 132(5):992–1002

https://doi.org/10.1097/ALN.0000000000003143

Published: May 2020

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Articles

Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial

Jacqueline M. Leung, M.D., M.P.H., Laura P. Sands, Ph.D., Ningning Chen, Ph.D., Christopher Ames, M.D., Sigurd Berven, M.D., Kevin Bozic, M.D., Shane Burch, M.D., Dean Chou, M.D., Kenneth Covinsky, M.D., Vedat Deviren, M.D., Sakura Kinjo, M.D., Joel H. Kramer, Psy.D., Michael Ries, M.D., Bobby Tay, M.D., Thomas Vail, M.D., Philip Weinstein, M.D., the Perioperative Medicine Research Group

Anesthesiology. October 2017: 127(4):633–644

https://doi.org/10.1097/ALN.0000000000001804

Published: October 2017

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Articles

Disambiguating Pharmacodynamic Efficacy from Behavior with Neuroimaging: Implications for Analgesic Drug Development

Vishvarani Wanigasekera, D.Phil., Melvin Mezue, D.Phil., Jesper Andersson, Ph.D., Yazhuo Kong, Ph.D., Irene Tracey, D.Phil.

Anesthesiology. January 2016: 124(1):159–168

https://doi.org/10.1097/ALN.0000000000000924

Published: January 2016

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Articles

A Perioperative Course of Gabapentin Does Not Produce a Clinically Meaningful Improvement in Analgesia after Cesarean Delivery: A Randomized Controlled Trial

David T. Monks, M.D., David W. Hoppe, M.D., Kristi Downey, M.Sc., Vibhuti Shah, M.D., Paul Bernstein, M.D., Jose C. A. Carvalho, M.D., Ph.D.

Anesthesiology. August 2015: 123(2):320–326

https://doi.org/10.1097/ALN.0000000000000722

Published: August 2015

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Articles

Perioperative Gabapentinoids: Choice of Agent, Dose, Timing, and Effects on Chronic Postsurgical Pain

Peter C. Schmidt, M.D., Gabriela Ruchelli, B.A., Sean C. Mackey, M.D., Ph.D., Ian R. Carroll, M.D., M.S. Epi.

Anesthesiology. November 2013: 119(5):1215–1221

https://doi.org/10.1097/ALN.0b013e3182a9a896

Published: November 2013

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Articles

Intrathecal Gabapentin to Treat Chronic Intractable Noncancer Pain

Richard Rauck, M.D., Robert J. Coffey, M.D., David M. Schultz, M.D., Mark S. Wallace, M.D., Lynn R. Webster, M.D., Sally E. McCarville, M.S., Eric J. Grigsby, M.D., Linda M. Page, Pharm.D.

Anesthesiology. September 2013: 119(3):675–686

https://doi.org/10.1097/ALN.0b013e3182a10fbf

Published: September 2013

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Articles

Anesthesia Literature Review

Anesthesiology. April 2013: 118(4):958–960

https://doi.org/10.1097/ALN.0b013e318288bb6c

Published: April 2013

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Articles

Gabapentin Inhibits γ-Amino Butyric Acid Release in the Locus Coeruleus but Not in the Spinal Dorsal Horn after Peripheral Nerve Injury in Rats

Masaru Yoshizumi, Ph.D., Renee A. Parker, B.S., James C. Eisenach, M.D., Ken-ichiro Hayashida, D.V.M., Ph.D.

Anesthesiology. June 2012: 116(6):1347–1353

https://doi.org/10.1097/ALN.0b013e318254e6fd

Published: June 2012

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Articles

Gabapentin Inhibits Catecholamine Release from Adrenal Chromaffin Cells

Robert D. Todd, M.D., Sarah M. McDavid, M.S., Rebecca L. Brindley, Ph.D., Mark L. Jewell, B.S., Kevin P. M. Currie, Ph.D.

Anesthesiology. May 2012: 116(5):1013–1024

https://doi.org/10.1097/ALN.0b013e31825153ea

Published: May 2012

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Articles

Pain Medicine

Timothy J. Brennan, Ph.D., M.D.

Anesthesiology. April 2010: 112(4):983–984

https://doi.org/10.1097/01.anes.0000369928.40880.ec

Published: April 2010

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Articles

Gabapentin Acts within the Locus Coeruleus to Alleviate Neuropathic Pain

Ken-ichiro Hayashida, D.V.M., Ph.D., Hideaki Obata, M.D., Ph.D., Kunie Nakajima, M.D., James C. Eisenach, M.D.

Anesthesiology. December 2008: 109(6):1077–1084

https://doi.org/10.1097/ALN.0b013e31818dac9c

Published: December 2008

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Articles

One from Column A and One from Column B: May I Take Your Order?

Markus Klass, M.D., Ph.D., Marie Csete, M.D., Ph.D.

Anesthesiology. August 2008: 109(2):165–166

https://doi.org/10.1097/ALN.0b013e31817f5867

Published: August 2008

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Articles

Gabapentin Prevents Delayed and Long-lasting Hyperalgesia Induced by Fentanyl in Rats

Alain C. Van Elstraete, M.D., Philippe Sitbon, M.D., Jean-Xavier Mazoit, M.D., Ph.D., Dan Benhamou, M.D.

Anesthesiology. March 2008: 108(3):484–494

https://doi.org/10.1097/ALN.0b013e318164cf85

Published: March 2008

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Articles

Complications—A Surgeon's Notes on an Imperfect Science

William Camann, M.D., David O. Warner, M.D.

Anesthesiology. June 2003: 98(6):1525

https://doi.org/10.1097/00000542-200306000-00052

Published: June 2003

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Articles

Magnesium Chloride and Ruthenium Red Attenuate the Antiallodynic Effect of Intrathecal Gabapentin in a Rat Model of Postoperative Pain

Jen-Kun Cheng, M.D., Yu-Jun Lai, M.S., Chien-Chuan Chen, M.D., Ching-Rong Cheng, M.D., Lih-Chu Chiou, Ph.D.

Anesthesiology. June 2003: 98(6):1472–1479

https://doi.org/10.1097/00000542-200306000-00026

Published: June 2003

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Articles

Gabapentin Blocks and Reverses Antinociceptive Morphine Tolerance in the Rat Paw-pressure and Tail-flick Tests

Ian Gilron, M.D., M.Sc., F.R.C.P.C., Jessica Biederman, B.Sc., Khem Jhamandas, Ph.D., Murray Hong, Ph.D.

Anesthesiology. May 2003: 98(5):1288–1292

https://doi.org/10.1097/00000542-200305000-00037

Published: May 2003

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Articles

Gabapentin Markedly Reduces Acetic Acid–induced Visceral Nociception

Yi Feng, M.D., Minglei Cui, Ph.D., William D. Willis, M.D., Ph.D.

Anesthesiology. March 2003: 98(3):729–733

https://doi.org/10.1097/00000542-200303000-00023

Published: March 2003

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Articles

Gabapentin and Pregabalin Can Interact Synergistically with Naproxen to Produce Antihyperalgesia

Robert W. Hurley, M.D., Ph.D., Debika Chatterjea, B.S., Meihua Rose Feng, Ph.D., Charles P. Taylor, Ph.D., Donna L. Hammond, Ph.D.

Anesthesiology. November 2002: 97(5):1263–1273

https://doi.org/10.1097/00000542-200211000-00033

Published: November 2002

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NARROW

Pharmacotherapy for the Prevention of Chronic Pain after Surgery in Adults: An Updated Systematic Review and Meta-analysis

Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis

Multimodal Analgesic Regimen for Spine Surgery: A Randomized Placebo-controlled Trial

Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial

Disambiguating Pharmacodynamic Efficacy from Behavior with Neuroimaging: Implications for Analgesic Drug Development

A Perioperative Course of Gabapentin Does Not Produce a Clinically Meaningful Improvement in Analgesia after Cesarean Delivery: A Randomized Controlled Trial

Perioperative Gabapentinoids: Choice of Agent, Dose, Timing, and Effects on Chronic Postsurgical Pain

Intrathecal Gabapentin to Treat Chronic Intractable Noncancer Pain

Anesthesia Literature Review

Gabapentin Inhibits γ-Amino Butyric Acid Release in the Locus Coeruleus but Not in the Spinal Dorsal Horn after Peripheral Nerve Injury in Rats

Gabapentin Inhibits Catecholamine Release from Adrenal Chromaffin Cells

Pain Medicine

Gabapentin Acts within the Locus Coeruleus to Alleviate Neuropathic Pain

One from Column A and One from Column B: May I Take Your Order?

Gabapentin Prevents Delayed and Long-lasting Hyperalgesia Induced by Fentanyl in Rats

Complications—A Surgeon's Notes on an Imperfect Science

Magnesium Chloride and Ruthenium Red Attenuate the Antiallodynic Effect of Intrathecal Gabapentin in a Rat Model of Postoperative Pain

Gabapentin Blocks and Reverses Antinociceptive Morphine Tolerance in the Rat Paw-pressure and Tail-flick Tests

Gabapentin Markedly Reduces Acetic Acid–induced Visceral Nociception

Gabapentin and Pregabalin Can Interact Synergistically with Naproxen to Produce Antihyperalgesia

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