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Articles

Slick Potassium Channels Control Pain and Itch in Distinct Populations of Sensory and Spinal Neurons in Mice

Cathrin Flauaus, R.Ph., Patrick Engel, R.Ph., Fangyuan Zhou, M.S., Jonas Petersen, Ph.D., Peter Ruth, Ph.D., Robert Lukowski, Ph.D., Achim Schmidtko, M.D., Ph.D., Ruirui Lu, M.D., Ph.D.

Anesthesiology. May 2022: 136(5):802–822

https://doi.org/10.1097/ALN.0000000000004163

Published: May 2022

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Articles

Overexpression of µ-Opioid Receptors in Peripheral Afferents, but Not in Combination with Enkephalin, Decreases Neuropathic Pain Behavior and Enhances Opioid Analgesia in Mouse

Amanda H. Klein, Ph.D., M.S., Husam K. Mohammad, Ph.D., R.Ph., Rabiah Ali, M.D., Brad Peper, D.M.D., Steven P. Wilson, Ph.D., Srinivasa N. Raja, M.D., Matthias Ringkamp, M.D., Ph.D., Sarah Sweitzer, Ph.D.

Anesthesiology. May 2018: 128(5):967–983

https://doi.org/10.1097/ALN.0000000000002063

Published: May 2018

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Articles

Hydrogen Peroxide Induces Muscle Nociception via Transient Receptor Potential Ankyrin 1 Receptors

Daisuke Sugiyama, M.D., Ph.D., Sinyoung Kang, M.D., Ph.D., Nicholas Arpey, B.A., Preeyaphan Arunakul, M.D., Yuriy M. Usachev, Ph.D., Timothy J. Brennan, M.D., Ph.D.

Anesthesiology. October 2017: 127(4):695–708

https://doi.org/10.1097/ALN.0000000000001756

Published: October 2017

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Articles

Impaired Pain-evoked Analgesia after Nerve Injury in Rats Reflects Altered Glutamate Regulation in the Locus Coeruleus

Masafumi Kimura, M.D., Ph.D., Takashi Suto, M.D., Ph.D., Carlos E. Morado-Urbina, B.S., Christopher M. Peters, Ph.D., James C. Eisenach, M.D., Ken-Ichiro Hayashida, D.V.M., Ph.D.

Anesthesiology. October 2015: 123(4):899–908

https://doi.org/10.1097/ALN.0000000000000796

Published: October 2015

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Articles

Bilateral Hypersensitivity to Capsaicin, Thermal, and Mechanical Stimuli in Unilateral Complex Regional Pain Syndrome

Astrid J. Terkelsen, M.D., Ph.D., Janne Gierthmühlen, M.D., Ph.D., Nanna B. Finnerup, M.D., Ph.D., Anders P. Højlund, M.D., Troels S. Jensen, M.D., Ph.D.

Anesthesiology. May 2014: 120(5):1225–1236

https://doi.org/10.1097/ALN.0000000000000220

Published: May 2014

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Articles

Nociceptor-selective Peripheral Nerve Block Induces Delayed Mechanical Hypersensitivity and Neurotoxicity in Rats

Christopher M. Peters, Ph.D., Douglas Ririe, M.D., Ph.D., Timothy T. Houle, Ph.D., Carol A. Aschenbrenner, M.A., James C. Eisenach, M.D.

Anesthesiology. April 2014: 120(4):976–986

https://doi.org/10.1097/ALN.0000000000000088

Published: April 2014

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Articles

σ 1 Receptors Are Involved in the Visceral Pain Induced by Intracolonic Administration of Capsaicin in Mice

Rafael González-Cano, M.Sc., Manuel Merlos, Ph.D., José M. Baeyens, M.D., Ph.D., Cruz M. Cendán, Ph.D.

Anesthesiology. March 2013: 118(3):691–700

https://doi.org/10.1097/ALN.0b013e318280a60a

Published: March 2013

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Articles

Differential Effects of Peripheral versus Central Coadministration of QX-314 and Capsaicin on Neuropathic Pain in Rats

Jun Shen, M.D., Lyle E. Fox, Ph.D., Jianguo Cheng, M.D., Ph.D.

Anesthesiology. August 2012: 117(2):365–380

https://doi.org/10.1097/ALN.0b013e318260de41

Published: August 2012

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Articles

The Quaternary Lidocaine Derivative, QX-314, Exerts Biphasic Effects on Transient Receptor Potential Vanilloid Subtype 1 Channels In Vitro

Ricardo E. Rivera-Acevedo, B.Sc., Stephan A. Pless, Ph.D., Christopher A. Ahern, Ph.D., Stephan K. W. Schwarz, M.D., Ph.D., F.R.C.P.C.

Anesthesiology. June 2011: 114(6):1425–1434

https://doi.org/10.1097/ALN.0b013e318216ea0c

Published: June 2011

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Articles

Protein Kinase A–dependent Spinal α-Amino-3-hydroxy-5-methyl-4-isoxazoleproprionate–receptor Trafficking Mediates Capsaicin-induced Colon-Urethra Cross-organ Reflex Sensitization

Hsien-Yu Peng, Ph.D., Chao-Hsiang Chang, M.D., Shin-Jei Tsai, M.D., Ph.D., Cheng-Yuan Lai, B.S., Kwong-Chung Tung, Ph.D., D.V.M., Hsi-Chin Wu, M.D., M.Sc., Tzer-Bin Lin, Ph.D.

Anesthesiology. January 2011: 114(1):70–83

https://doi.org/10.1097/ALN.0b013e3181fe4204

Published: January 2011

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Articles

Effects of Intrathecal Ketorolac on Human Experimental Pain

James C. Eisenach, M.D., Regina Curry, R.N., Chuanyao Tong, M.D., Timothy T. Houle, Ph.D., Tony L. Yaksh, Ph.D.

Anesthesiology. May 2010: 112(5):1216–1224

https://doi.org/10.1097/ALN.0b013e3181d94d8b

Published: May 2010

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Articles

QX-314 Produces Long-lasting Local Anesthesia Modulated by Transient Receptor Potential Vanilloid Receptors in Mice

Craig R. Ries, M.D., Ph.D., F.R.C.P.C., Ray Pillai, B.Sc., Cheryl C. W. Chung, B.Sc., Jimmy T. C. Wang, M.Sc., Bernard A. MacLeod, M.D., F.R.C.P.C., Stephan K. W. Schwarz, M.D., Ph.D., F.R.C.P.C.

Anesthesiology. July 2009: 111(1):122–126

https://doi.org/10.1097/ALN.0b013e3181a9160e

Published: July 2009

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Articles

Coapplication of Lidocaine and the Permanently Charged Sodium Channel Blocker QX-314 Produces a Long-lasting Nociceptive Blockade in Rodents

Alexander M. Binshtok, Ph.D., Peter Gerner, M.D., Seog Bae Oh, D.D.S., Ph.D., Michelino Puopolo, Ph.D., Suzuko Suzuki, M.D., David P. Roberson, M.B.A., Teri Herbert, B.Sc., Chi-Fei Wang, M.D., Donghoon Kim, B.S., Gehoon Chung, D.D.S., Aya A. Mitani, M.P.H., Ging Kuo Wang, Ph.D., Bruce P. Bean, Ph.D., Clifford J. Woolf, M.D., Ph.D.

Anesthesiology. July 2009: 111(1):127–137

https://doi.org/10.1097/ALN.0b013e3181a915e7

Published: July 2009

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Articles

Capsaicin Combined with Local Anesthetics Preferentially Prolongs Sensory/Nociceptive Block in Rat Sciatic Nerve

Peter Gerner, M.D., Alexander M. Binshtok, Ph.D., Chi-Fei Wang, M.D., Nathanael D. Hevelone, M.P.H., Bruce P. Bean, Ph.D., Clifford J. Woolf, Ph.D., Ging Kuo Wang, Ph.D.

Anesthesiology. November 2008: 109(5):872–878

https://doi.org/10.1097/ALN.0b013e31818958f7

Published: November 2008

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Articles

Lack of Analgesia by Oral Standardized Cannabis Extract on Acute Inflammatory Pain and Hyperalgesia in Volunteers

Birgit Kraft, M.D., Nathalie A. Frickey, M.D., Rainer M. Kaufmann, M.D., Marcus Reif, Ph.D., Richard Frey, M.D., Burkhard Gustorff, M.D., Hans G. Kress, M.D., Ph.D.

Anesthesiology. July 2008: 109(1):101–110

https://doi.org/10.1097/ALN.0b013e31817881e1

Published: July 2008

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Articles

Effect of AMG0347, a Transient Receptor Potential Type V1 Receptor Antagonist, and Morphine on Pain Behavior after Plantar Incision

Chaoran Wu, M.D., Ph.D., Narender R. Gavva, Ph.D., Timothy J. Brennan, M.D., Ph.D.

Anesthesiology. June 2008: 108(6):1100–1108

https://doi.org/10.1097/ALN.0b013e31817302b3

Published: June 2008

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Articles

Painful Nerve Injury Shortens the Intracellular Ca 2+ Signal in Axotomized Sensory Neurons of Rats

Andreas Fuchs, M.D., Marcel Rigaud, M.D., Quinn H. Hogan, M.D.

Anesthesiology. July 2007: 107(1):106–116

https://doi.org/10.1097/01.anes.0000267538.72900.68

Published: July 2007

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Articles

Synergistic Antinociceptive Effects of Ketamine and Morphine in the Orofacial Capsaicin Test in the Rat

Pedro Alvarez, D.V.M., Gloria Saavedra, D.D.S., Alejandro Hernández, D.D.S., Carlos Paeile, D.D.S., Teresa Pelissier, D.D.S.

Anesthesiology. October 2003: 99(4):969–975

https://doi.org/10.1097/00000542-200310000-00033

Published: October 2003

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Articles

Fentanyl Decreases Ca 2+ Currents in a Population of Capsaicin-responsive Sensory Neurons

Thomas S. McDowell, M.D., Ph.D.

Anesthesiology. January 2003: 98(1):223–231

https://doi.org/10.1097/00000542-200301000-00034

Published: January 2003

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Articles

Ketamine Differentially Blocks Sensory Afferent Synaptic Transmission in Medial Nucleus Tractus Solitarius (mNTS)

Young-Ho Jin, Ph.D., Timothy W. Bailey, Ph.D., Mark W. Doyle, Ph.D., Bai-yan Li, M.D., Ph.D., Kyoung S. K. Chang, M.D., Ph.D., John H. Schild, Ph.D., David Mendelowitz, Ph.D., Michael C. Andresen, Ph.D.

Anesthesiology. January 2003: 98(1):121–132

https://doi.org/10.1097/00000542-200301000-00021

Published: January 2003

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NARROW

Slick Potassium Channels Control Pain and Itch in Distinct Populations of Sensory and Spinal Neurons in Mice

Overexpression of µ-Opioid Receptors in Peripheral Afferents, but Not in Combination with Enkephalin, Decreases Neuropathic Pain Behavior and Enhances Opioid Analgesia in Mouse

Hydrogen Peroxide Induces Muscle Nociception via Transient Receptor Potential Ankyrin 1 Receptors

Impaired Pain-evoked Analgesia after Nerve Injury in Rats Reflects Altered Glutamate Regulation in the Locus Coeruleus

Bilateral Hypersensitivity to Capsaicin, Thermal, and Mechanical Stimuli in Unilateral Complex Regional Pain Syndrome

Nociceptor-selective Peripheral Nerve Block Induces Delayed Mechanical Hypersensitivity and Neurotoxicity in Rats

σ 1 Receptors Are Involved in the Visceral Pain Induced by Intracolonic Administration of Capsaicin in Mice

Differential Effects of Peripheral versus Central Coadministration of QX-314 and Capsaicin on Neuropathic Pain in Rats

The Quaternary Lidocaine Derivative, QX-314, Exerts Biphasic Effects on Transient Receptor Potential Vanilloid Subtype 1 Channels In Vitro

Protein Kinase A–dependent Spinal α-Amino-3-hydroxy-5-methyl-4-isoxazoleproprionate–receptor Trafficking Mediates Capsaicin-induced Colon-Urethra Cross-organ Reflex Sensitization

Effects of Intrathecal Ketorolac on Human Experimental Pain

QX-314 Produces Long-lasting Local Anesthesia Modulated by Transient Receptor Potential Vanilloid Receptors in Mice

Coapplication of Lidocaine and the Permanently Charged Sodium Channel Blocker QX-314 Produces a Long-lasting Nociceptive Blockade in Rodents

Capsaicin Combined with Local Anesthetics Preferentially Prolongs Sensory/Nociceptive Block in Rat Sciatic Nerve

Lack of Analgesia by Oral Standardized Cannabis Extract on Acute Inflammatory Pain and Hyperalgesia in Volunteers

Effect of AMG0347, a Transient Receptor Potential Type V1 Receptor Antagonist, and Morphine on Pain Behavior after Plantar Incision

Painful Nerve Injury Shortens the Intracellular Ca 2+ Signal in Axotomized Sensory Neurons of Rats

Synergistic Antinociceptive Effects of Ketamine and Morphine in the Orofacial Capsaicin Test in the Rat

Fentanyl Decreases Ca 2+ Currents in a Population of Capsaicin-responsive Sensory Neurons

Ketamine Differentially Blocks Sensory Afferent Synaptic Transmission in Medial Nucleus Tractus Solitarius (mNTS)

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