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Local Anesthetic Cardiac Toxicity Is Mediated by Cardiomyocyte Calcium Dynamics

Julia Plakhotnik, B.Sc., Libo Zhang, M.D., Ph.D., Marvin Estrada, R.V.T., John G. Coles, M.D., Per-Arne Lonnqvist, M.D., Ph.D., Jason T. Maynes, M.D., Ph.D.

Anesthesiology. December 2022: 137(6):687–703

DOI: https://doi.org/10.1097/ALN.0000000000004389

Published: December 2022

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Articles

Journal-related Activities and Other Special Activities at the 2021 American Society of Anesthesiologists Meeting

Michael J. Avram, Ph.D., Deborah J. Culley, M.D., Evan D. Kharasch, M.D., Ph.D., Jerrold H. Levy, M.D., F.C.C.M., Martin J. London, M.D.

Anesthesiology. October 2021: 135(4):576–584

DOI: https://doi.org/10.1097/ALN.0000000000003949

Published: October 2021

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Articles

Molecular Modification of Transient Receptor Potential Canonical 6 Channels Modulates Calcium Dyshomeostasis in a Mouse Model Relevant to Malignant Hyperthermia

Jose Rafael Lopez, M.D., Ph.D., Arkady Uryash, M.D., Ph.D., Jose Adams, M.D., Philip M. Hopkins, M.D., F.R.C.A., Paul D. Allen, M.D., Ph.D.

Anesthesiology. February 2021: 134(2):234–247

DOI: https://doi.org/10.1097/ALN.0000000000003635

Published: February 2021

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Articles

Transient Receptor Potential Cation Channels and Calcium Dyshomeostasis in a Mouse Model Relevant to Malignant Hyperthermia

Jose Rafael Lopez, M.D., Ph.D., Vikas Kaura, M.D., Phillip Hopkins, M.D., Xiaochen Liu, Ph.D., Arkady Uryach, M.D., Ph.D., Jose Adams, M.D., Paul D. Allen, M.D., Ph.D

Anesthesiology. August 2020: 133(2):364–376

DOI: https://doi.org/10.1097/ALN.0000000000003387

Published: August 2020

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Articles

Cross-talk between Human Spinal Cord μ-opioid Receptor 1Y Isoform and Gastrin-releasing Peptide Receptor Mediates Opioid-induced Scratching Behavior

Xian-Yu Liu, Ph.D., Yehuda Ginosar, M.B.B.S., Joseph Yazdi, M.D., Alexander Hincker, M.D., Zhou-Feng Chen, Ph.D.

Anesthesiology. August 2019: 131(2):381–391

DOI: https://doi.org/10.1097/ALN.0000000000002776

Published: August 2019

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Articles

Up-regulation of Intracellular Calcium Handling Underlies the Recovery of Endotoxemic Cardiomyopathy in Mice

Justin C. Morse, Joanne Huang, Natasha Khona, Edward J. Miller, M.D., Ph.D., Deborah A. Siwik, Ph.D., Wilson S. Colucci, M.D., Ion A. Hobai, M.D., Ph.D.

Anesthesiology. June 2017: 126(6):1125–1138

DOI: https://doi.org/10.1097/ALN.0000000000001627

Published: June 2017

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Articles

Involvement of Cyclophilin D and Calcium in Isoflurane-induced Preconditioning

Geoffrey Teixeira, Ph.D., Pascal Chiari, M.D., Ph.D., Jeremy Fauconnier, Ph.D., Maryline Abrial, Ph.D., Elisabeth Couture-Lepetit, M.Sc., Rania Harisseh, Ph.D., Bruno Pillot, Ph.D., Alain Lacampagne, Ph.D., Yves Tourneur, Ph.D., Abdallah Gharib, Ph.D., Michel Ovize, M.D., Ph.D.

Anesthesiology. December 2015: 123(6):1374–1384

DOI: https://doi.org/10.1097/ALN.0000000000000876

Published: December 2015

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Articles

What Would a Proper Explanation of Anesthesia Look Like?

Jamie Sleigh, M.D., Darren Hight, B.Sc.

Anesthesiology. June 2015: 122(6):1196–1197

DOI: https://doi.org/10.1097/ALN.0000000000000672

Published: June 2015

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Articles

Efficient Extra- and Intracellular Alkalinization Improves Cardiovascular Functions in Severe Lactic Acidosis Induced by Hemorrhagic Shock

Antoine Kimmoun, M.D., Nicolas Ducrocq, M.D., Nacira Sennoun, Ph.D., Khodr Issa, Ph.D., Charlène Strub, L.T., Jean-Marie Escanyé, Ph.D., Sébastien Leclerc, Ph.D., Bruno Levy, M.D., Ph.D.

Anesthesiology. April 2014: 120(4):926–934

DOI: https://doi.org/10.1097/ALN.0000000000000077

Published: April 2014

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Articles

Despite Differences in Cytosolic Calcium Regulation, Lidocaine Toxicity Is Similar in Adult and Neonatal Rat Dorsal Root Ganglia In Vitro

Lisa V. Doan, M.D., Olga Eydlin, M.D., Boris Piskoun, B.A., Richard P. Kline, Ph.D., Esperanza Recio-Pinto, Ph.D., Andrew D. Rosenberg, M.D., Thomas J. J. Blanck, M.D., Ph.D., Fang Xu, Ph.D.

Anesthesiology. January 2014: 120(1):50–61

DOI: https://doi.org/10.1097/ALN.0b013e3182a2a561

Published: January 2014

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Articles

Skeletal Muscle Ryanodine Receptor Mutations Associated with Malignant Hyperthermia Showed Enhanced Intensity and Sensitivity to Triggering Drugs when Expressed in Human Embryonic Kidney Cells

Keisaku Sato, Ph.D., Cornelia Roesl, M.Sc., Neil Pollock, M.B.Ch.B., F.R.C.A., F.A.N.Z.C.A., M.D., Kathryn M. Stowell, Ph.D.

Anesthesiology. July 2013: 119(1):111–118

DOI: https://doi.org/10.1097/ALN.0b013e31828cebfe

Published: July 2013

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Articles

Pungent General Anesthetics Activate Transient Receptor Potential-A1 to Produce Hyperalgesia and Neurogenic Bronchoconstriction

Helge Eilers, M.D., Fiore Cattaruzza, Ph.D., Romina Nassini, Ph.D., Serena Materazzi, Ph.D., Eunice Andre, Ph.D., Catherine Chu, B.A., Graeme S. Cottrell, Ph.D., Mark Schumacher, Ph.D., M.D., Pierangelo Geppetti, M.D., Nigel W. Bunnett, Ph.D.

Anesthesiology. June 2010: 112(6):1452–1463

DOI: https://doi.org/10.1097/ALN.0b013e3181d94e00

Published: June 2010

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Articles

Axotomy Depletes Intracellular Calcium Stores in Primary Sensory Neurons

Marcel Rigaud, M.D., Geza Gemes, M.D., Paul D. Weyker, B.S., James M. Cruikshank, B.S., Takashi Kawano, M.D., Hsiang-En Wu, M.D., Quinn H. Hogan, M.D.

Anesthesiology. August 2009: 111(2):381–392

DOI: https://doi.org/10.1097/ALN.0b013e3181ae6212

Published: August 2009

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Articles

Depletion of Calcium Stores in Injured Sensory Neurons: Anatomic and Functional Correlates

Geza Gemes, M.D., Marcel Rigaud, M.D., Paul D. Weyker, B.S., Stephen E. Abram, M.D., Dorothee Weihrauch, DVM, Ph.D., Mark Poroli, B.S., Vasiliki Zoga, M.D., Quinn H. Hogan, M.D.

Anesthesiology. August 2009: 111(2):393–405

DOI: https://doi.org/10.1097/ALN.0b013e3181ae63b0

Published: August 2009

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Articles

Desflurane-induced Postconditioning Is Mediated by β-Adrenergic Signaling: Role of β1- and β2-Adrenergic Receptors, Protein Kinase A, and Calcium/Calmodulin-dependent Protein Kinase II

Markus Lange, M.D., Andreas Redel, M.D., Christopher Lotz, M.D., Thorsten M. Smul, M.D., Christoph Blomeyer, M.D., Anja Frank, B.S., Jan Stumpner, M.D., Norbert Roewer, M.D., Ph.D., Franz Kehl, M.D., Ph.D., D.E.A.A.

Anesthesiology. March 2009: 110(3):516–528

DOI: https://doi.org/10.1097/ALN.0b013e318197ff62

Published: March 2009

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Articles

Inhalational Anesthetics Induce Cell Damage by Disruption of Intracellular Calcium Homeostasis with Different Potencies

Hui Yang, M.D., Ge Liang, M.D., Brian J. Hawkins, Ph.D., Muniswamy Madesh, Ph.D., Andrew Pierwola, M.D., Huafeng Wei, M.D., Ph.D.

Anesthesiology. August 2008: 109(2):243–250

DOI: https://doi.org/10.1097/ALN.0b013e31817f5c47

Published: August 2008

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Articles

Differential Role of Calcium/Calmodulin-dependent Protein Kinase II in Desflurane-induced Preconditioning and Cardioprotection by Metoprolol: Metoprolol Blocks Desflurane-induced Preconditioning

Markus Lange, M.D., Thorsten M. Smul, M.D., Andreas Redel, M.D., Christopher Lotz, M.D., Virginija Jazbutyte, M.Sc., Verena Schnupp, B.S., Norbert Roewer, M.D., Ph.D., Franz Kehl, M.D., Ph.D., D.E.A.A.

Anesthesiology. July 2008: 109(1):72–80

DOI: https://doi.org/10.1097/ALN.0b013e31817be96c

Published: July 2008

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Articles

Nitrosative Stress and Myocardial Sarcoplasmic Endoreticular Calcium Adenosine Triphosphatase Subtype 2a Activity after Lung Resection in Swine

Paul M. Heerdt, M.D., Ph.D., Paul Lane, Ph.D., Brian Y. Pan, B.S., Ulrich Schaefer, M.D., Mark Crabtree, Ph.D., Roger Hong, B.S., Andrew A. M. Singer, B.S., Roberto Levi, M.D., Bernard J. Park, M.D.

Anesthesiology. December 2007: 107(6):954–962

DOI: https://doi.org/10.1097/01.anes.0000291446.70921.61

Published: December 2007

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Articles

Contribution of Calcium Channel Subtypes to the Intracellular Calcium Signal in Sensory Neurons: The Effect of Injury

Andreas Fuchs, M.D., Marcel Rigaud, M.D., Constantine D. Sarantopoulos, M.D., Ph.D., Patrick Filip, M.D., Quinn H. Hogan, M.D.

Anesthesiology. July 2007: 107(1):117–127

DOI: https://doi.org/10.1097/01.anes.0000267511.21864.93

Published: July 2007

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Articles

Intravenous Anesthetics Inhibit Capacitative Calcium Entry in Pulmonary Venous Smooth Muscle Cells

Sachiko Shimizu, M.D., Xueqin Ding, M.D., Ph.D., Paul A. Murray, Ph.D.

Anesthesiology. April 2006: 104(4):791–797

DOI: https://doi.org/10.1097/00000542-200604000-00025

Published: April 2006

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NARROW

Local Anesthetic Cardiac Toxicity Is Mediated by Cardiomyocyte Calcium Dynamics

Journal-related Activities and Other Special Activities at the 2021 American Society of Anesthesiologists Meeting

Molecular Modification of Transient Receptor Potential Canonical 6 Channels Modulates Calcium Dyshomeostasis in a Mouse Model Relevant to Malignant Hyperthermia

Transient Receptor Potential Cation Channels and Calcium Dyshomeostasis in a Mouse Model Relevant to Malignant Hyperthermia

Cross-talk between Human Spinal Cord μ-opioid Receptor 1Y Isoform and Gastrin-releasing Peptide Receptor Mediates Opioid-induced Scratching Behavior

Up-regulation of Intracellular Calcium Handling Underlies the Recovery of Endotoxemic Cardiomyopathy in Mice

Involvement of Cyclophilin D and Calcium in Isoflurane-induced Preconditioning

What Would a Proper Explanation of Anesthesia Look Like?

Efficient Extra- and Intracellular Alkalinization Improves Cardiovascular Functions in Severe Lactic Acidosis Induced by Hemorrhagic Shock

Despite Differences in Cytosolic Calcium Regulation, Lidocaine Toxicity Is Similar in Adult and Neonatal Rat Dorsal Root Ganglia In Vitro

Skeletal Muscle Ryanodine Receptor Mutations Associated with Malignant Hyperthermia Showed Enhanced Intensity and Sensitivity to Triggering Drugs when Expressed in Human Embryonic Kidney Cells

Pungent General Anesthetics Activate Transient Receptor Potential-A1 to Produce Hyperalgesia and Neurogenic Bronchoconstriction

Axotomy Depletes Intracellular Calcium Stores in Primary Sensory Neurons

Depletion of Calcium Stores in Injured Sensory Neurons: Anatomic and Functional Correlates

Desflurane-induced Postconditioning Is Mediated by β-Adrenergic Signaling: Role of β1- and β2-Adrenergic Receptors, Protein Kinase A, and Calcium/Calmodulin-dependent Protein Kinase II

Inhalational Anesthetics Induce Cell Damage by Disruption of Intracellular Calcium Homeostasis with Different Potencies

Differential Role of Calcium/Calmodulin-dependent Protein Kinase II in Desflurane-induced Preconditioning and Cardioprotection by Metoprolol: Metoprolol Blocks Desflurane-induced Preconditioning

Nitrosative Stress and Myocardial Sarcoplasmic Endoreticular Calcium Adenosine Triphosphatase Subtype 2a Activity after Lung Resection in Swine

Contribution of Calcium Channel Subtypes to the Intracellular Calcium Signal in Sensory Neurons: The Effect of Injury

Intravenous Anesthetics Inhibit Capacitative Calcium Entry in Pulmonary Venous Smooth Muscle Cells

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