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Articles

Local Anesthetic Cardiac Toxicity Is Mediated by Cardiomyocyte Calcium Dynamics

This article has a Visual Abstract
Julia Plakhotnik, B.Sc., Libo Zhang, M.D., Ph.D., Marvin Estrada, R.V.T., John G. Coles, M.D., Per-Arne Lonnqvist, M.D., Ph.D., Jason T. Maynes, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. December 2022: 137(6):687–703
DOI: https://doi.org/10.1097/ALN.0000000000004389
Published: December 2022
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Evaluation of Diaphragmatic Function after Interscalene Block with Liposomal Bupivacaine: A Randomized Controlled Trial

This article has a Visual Abstract This article has an Audio Podcast
Aaron A. Berg, D.O., James M. Flaherty, M.D., Jason M. Habeck, M.D., Alicia K. Harrison, M.D., Jonathan P. Braman, M.D., Alexander M. Kaizer, Ph.D., Jacob L. Hutchins, M.D.
Publication: Anesthesiology
Anesthesiology. April 2022: 136(4):531–541
DOI: https://doi.org/10.1097/ALN.0000000000004118
Published: April 2022
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Prolonged Phrenic Nerve Blockade with Liposomal Bupivacaine

Lei Xu, M.D., Ban C. H. Tsui, M.D., M.Sc., Jean-Louis Horn, M.D.
Publication: Anesthesiology
Anesthesiology. April 2022: 136(4):525–527
DOI: https://doi.org/10.1097/ALN.0000000000004160
Published: April 2022
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Interscalene Brachial Plexus Block with Liposomal Bupivacaine versus Standard Bupivacaine with Perineural Dexamethasone: A Noninferiority Trial

This article has a Visual Abstract This article has an Audio Podcast
David H. Kim, M.D., Jiabin Liu, M.D., Ph.D., Jonathan C. Beathe, M.D., Yi Lin, M.D., Ph.D., Douglas S. Wetmore, M.D., Sang J. Kim, M.D., Stephen C. Haskins, M.D., Sean Garvin, M.D., Joseph A. Oxendine, M.D., Michael C. Ho, M.D., Answorth A. Allen, M.D., Marko Popovic, B.S., Ejiro Gbaje, M.P.H., Christopher L. Wu, M.D., Stavros G. Memtsoudis, M.D., Ph.D., M.B.A.
Publication: Anesthesiology
Anesthesiology. March 2022: 136(3):434–447
DOI: https://doi.org/10.1097/ALN.0000000000004111
Published: March 2022
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Spinal Anesthesia Reduces Myocardial Ischemia–triggered Ventricular Arrhythmias by Suppressing Spinal Cord Neuronal Network Interactions in Pigs

Yukiko Omura, M.D., Jasmine P. Kipke, B.S., Siamak Salavatian, Ph.D., Andrew Shea Afyouni, B.S., Christian Wooten, B.A., Robert F. Herkenham, M.S.E., Uri Maoz, Ph.D., Elnaz Lashgari, M.S., Erica A. Dale, Ph.D., Kimberly Howard-Quijano, M.D., M.S., Aman Mahajan, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. March 2021: 134(3):405–420
DOI: https://doi.org/10.1097/ALN.0000000000003662
Published: March 2021
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Liposomal Bupivacaine: Effective, Cost-effective, or (Just) Costly?

Mary Ellen McCann, M.D.
Publication: Anesthesiology
Anesthesiology. February 2021: 134(2):139–142
DOI: https://doi.org/10.1097/ALN.0000000000003658
Published: February 2021
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Perineural Liposomal Bupivacaine Is Not Superior to Nonliposomal Bupivacaine for Peripheral Nerve Block Analgesia: A Systematic Review and Meta-analysis

Nasir Hussain, M.D., M.Sc., Richard Brull, M.D., Brendan Sheehy, M.D., Michael K. Essandoh, M.D., David L. Stahl, M.D., Tristan E. Weaver, M.D., Faraj W. Abdallah, M.D., M.Sc.
Publication: Anesthesiology
Anesthesiology. February 2021: 134(2):147–164
DOI: https://doi.org/10.1097/ALN.0000000000003651
Published: February 2021
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Clinical Effectiveness of Liposomal Bupivacaine Administered by Infiltration or Peripheral Nerve Block to Treat Postoperative Pain: A Narrative Review

Brian M. Ilfeld, M.D., M.S., James C. Eisenach, M.D., Rodney A. Gabriel, M.D., M.S.
Publication: Anesthesiology
Anesthesiology. February 2021: 134(2):283–344
DOI: https://doi.org/10.1097/ALN.0000000000003630
Published: February 2021
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Bursting the Liposomal Bubble: Sustained-release vs. Plain Bupivacaine

Jonathan P. Wanderer, James P. Rathmell
Publication: Anesthesiology
Anesthesiology. February 2021: 134(2):A17
DOI: https://doi.org/10.1097/ALN.0000000000003677
Published: February 2021
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L-bupivacaine Inhibition of Nociceptive Transmission in Rat Peripheral and Dorsal Horn Neurons

Daisuke Uta, Ph.D., Kohei Koga, Ph.D., Hidemasa Furue, Ph.D., Keiji Imoto, M.D., Ph.D., Megumu Yoshimura, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. January 2021: 134(1):88–102
DOI: https://doi.org/10.1097/ALN.0000000000003596
Published: January 2021
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Left Ventricular Hypertrophy Increases Susceptibility to Bupivacaine-induced Cardiotoxicity through Overexpression of Transient Receptor Potential Canonical Channels in Rats

Hideki Hino, M.D., Tadashi Matsuura, M.D., Ph.D., Miyuki Kuno, M.D., Ph.D., Kotaro Hori, M.D., Ph.D., Shogo Tsujikawa, M.D., Ph.D., Takashi Mori, M.D., Ph.D., Kiyonobu Nishikawa, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. November 2020: 133(5):1077–1092
DOI: https://doi.org/10.1097/ALN.0000000000003554
Published: November 2020
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Anesthetic and Analgesic Drug Products Advisory Committee Activity and Decisions in the Opioid-crisis Era

Ronald S. Litman, D.O., M.L.
Publication: Anesthesiology
Anesthesiology. October 2020: 133(4):740–749
DOI: https://doi.org/10.1097/ALN.0000000000003485
Published: October 2020
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Mepivacaine versus Bupivacaine Spinal Anesthesia for Early Postoperative Ambulation: A Randomized Controlled Trial

Eric S. Schwenk, M.D., Vincent P. Kasper, M.D., Jordan D. Smoker, M.D., Andrew M. Mendelson, D.O., Matthew S. Austin, M.D., Scot A. Brown, M.D., William J. Hozack, M.D., Alexa J. Cohen, B.S., Jonathan J. Li, B.S., Christopher S. Wahal, M.D., Jaime L. Baratta, M.D., Marc C. Torjman, Ph.D., Alyson C. Nemeth, M.P.T., Eric E. Czerwinski, M.S.P.T.
Publication: Anesthesiology
Anesthesiology. October 2020: 133(4):801–811
DOI: https://doi.org/10.1097/ALN.0000000000003480
Published: October 2020
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Liposomal Bupivacaine Infiltration for Knee Arthroplasty: Significant Analgesic Benefits or Just a Bunch of Fat?

Brian M. Ilfeld, M.D., M.S., Rodney A. Gabriel, M.D., M.A.S., James C. Eisenach, M.D.
Publication: Anesthesiology
Anesthesiology. October 2018: 129(4):623–626
DOI: https://doi.org/10.1097/ALN.0000000000002386
Published: October 2018
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Effect of Thoracic Epidural Anesthesia in a Rat Model of Phrenic Motor Inhibition after Upper Abdominal Surgery

Won-Seok Chae, M.D., Soron Choi, M.D., Ph.D., Daisuke Sugiyama, M.D., Ph.D., George B. Richerson, M.D., Ph.D., Timothy J. Brennan, M.D., Ph.D., Sinyoung Kang, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. October 2018: 129(4):791–807
DOI: https://doi.org/10.1097/ALN.0000000000002331
Published: October 2018
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Liposomal Bupivacaine Does Not Reduce Inpatient Opioid Prescription or Related Complications after Knee Arthroplasty: A Database Analysis

Lukas Pichler, M.D., Jashvant Poeran, M.D., Ph.D., Nicole Zubizarreta, M.P.H., Crispiana Cozowicz, M.D., Eric C. Sun, M.D., Ph.D., Madhu Mazumdar, Ph.D., Stavros G. Memtsoudis, M.D., Ph.D., F.C.C.P.
Publication: Anesthesiology
Anesthesiology. October 2018: 129(4):689–699
DOI: https://doi.org/10.1097/ALN.0000000000002267
Published: October 2018
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Free Fatty Acid Receptor G-protein–coupled Receptor 40 Mediates Lipid Emulsion-induced Cardioprotection

Soban Umar, M.D., Ph.D., Jingyuan Li, M.D., Ph.D., Kyle Hannabass, M.D., Mylene Vaillancourt, M.Sc., Christine M. Cunningham, B.S., Shayan Moazeni, B.S., Aman Mahajan, M.D., Ph.D., Mansoureh Eghbali, Ph.D.
Publication: Anesthesiology
Anesthesiology. July 2018: 129(1):154–162
DOI: https://doi.org/10.1097/ALN.0000000000002195
Published: July 2018
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In Vitro Negative Inotropic Effect of Low Concentrations of Bupivacaine Relates to Diminished Ca 2+ Sensitivity but Not to Ca 2+ Handling or β-Adrenoceptor Signaling

Frederik Flenner, Ph.D., Nicole Arlt, Ph.D., Mahtab Nasib, cand.med., Sophie Schobesberger, Ph.D., Thea Koch, M.D., Ursula Ravens, M.D., Felix Friedrich, M.D., Viacheslav Nikolaev, Ph.D., Torsten Christ, M.D., Sebastian N. Stehr, M.D.
Publication: Anesthesiology
Anesthesiology. June 2018: 128(6):1175–1186
DOI: https://doi.org/10.1097/ALN.0000000000002180
Published: June 2018
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Bupivacaine Indirectly Potentiates Glutamate-induced Intracellular Calcium Signaling in Rat Hippocampal Neurons by Impairing Mitochondrial Function in Cocultured Astrocytes

Yuan Xing, M.Med., Nan Zhang, M.Med., Wei Zhang, M.D., Ph.D., Lei-Ming Ren, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. March 2018: 128(3):539–554
DOI: https://doi.org/10.1097/ALN.0000000000002003
Published: March 2018
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Effect of Thoracic Epidural Ropivacaine versus Bupivacaine on Lower Urinary Tract Function: A Randomized Clinical Trial

Stefan A. Girsberger, M.D., Marc P. Schneider, M.D., Ph.D., Lukas M. Löffel, M.D., Fiona C. Burkhard, M.D., Patrick Y. Wuethrich, M.D.
Publication: Anesthesiology
Anesthesiology. March 2018: 128(3):511–519
DOI: https://doi.org/10.1097/ALN.0000000000001980
Published: March 2018
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