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Articles

Dexmedetomidine Exerts an Anti-inflammatory Effect via α 2 Adrenoceptors to Prevent Lipopolysaccharide-induced Cognitive Decline in Mice

Rong Li, M.D., Ieng K. Lai, B.S., Jonathan Z. Pan, M.D., Ph.D., Pengbo Zhang, M.D., Ph.D., Mervyn Maze, M.B., Ch.B.

Anesthesiology. August 2020: 133(2):393–407

DOI: https://doi.org/10.1097/ALN.0000000000003390

Published: August 2020

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Articles

In Vitro Negative Inotropic Effect of Low Concentrations of Bupivacaine Relates to Diminished Ca 2+ Sensitivity but Not to Ca 2+ Handling or β-Adrenoceptor Signaling

Frederik Flenner, Ph.D., Nicole Arlt, Ph.D., Mahtab Nasib, cand.med., Sophie Schobesberger, Ph.D., Thea Koch, M.D., Ursula Ravens, M.D., Felix Friedrich, M.D., Viacheslav Nikolaev, Ph.D., Torsten Christ, M.D., Sebastian N. Stehr, M.D.

Anesthesiology. June 2018: 128(6):1175–1186

DOI: https://doi.org/10.1097/ALN.0000000000002180

Published: June 2018

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Articles

Overexpression of Cyclic Adenosine Monophosphate Effluent Protein MRP4 Induces an Altered Response to β-Adrenergic Stimulation in the Senescent Rat Heart

Aude Carillion, M.D., Sarah Feldman, Cheng Jiang, M.D., Fabrice Atassi, Ph.D., Na Na, M.D., Nathalie Mougenot, Sophie Besse, Ph.D., Jean-Sébastien Hulot, M.D., Ph.D., Bruno Riou, M.D., Ph.D., Julien Amour, M.D., Ph.D.

Anesthesiology. February 2015: 122(2):334–342

DOI: https://doi.org/10.1097/ALN.0000000000000526

Published: February 2015

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Articles

Interaction of Metabolic and Respiratory Acidosis with α and β-adrenoceptor Stimulation in Rat Myocardium

Matthieu Biais, M.D., Romain Jouffroy, M.D., Aude Carillion, M.D., Sarah Feldman, Aude Jobart-Malfait, B.S., Bruno Riou, M.D., Ph.D., Julien Amour, M.D., Ph.D.

Anesthesiology. December 2012: 117(6):1212–1222

DOI: https://doi.org/10.1097/ALN.0b013e3182753264

Published: December 2012

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Articles

Ondansetron Reverses Antihypersensitivity from Clonidine in Rats after Peripheral Nerve Injury: Role of γ-Aminobutyric Acid in α2-Adrenoceptor and 5-HT3 Serotonin Receptor Analgesia

Ken-ichiro Hayashida, D.V.M., Ph.D., Masafumi Kimura, M.D., Masaru Yoshizumi, Ph.D., Shotaro Hobo, M.D., Hideaki Obata, M.D., Ph.D., James C. Eisenach, M.D.

Anesthesiology. August 2012: 117(2):389–398

DOI: https://doi.org/10.1097/ALN.0b013e318260d381

Published: August 2012

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Articles

Anesthesia Literature Review

Timothy J. Brennan, Ph.D., M.D.

Anesthesiology. December 2011: 115(6):1303–1307

DOI: https://doi.org/10.1097/ALN.0b013e318238ebe5

Published: December 2011

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Articles

Perineural Dexmedetomidine Added to Ropivacaine for Sciatic Nerve Block in Rats Prolongs the Duration of Analgesia by Blocking the Hyperpolarization-activated Cation Current

Chad M. Brummett, M.D., Elizabeth K. Hong, B.S., Allison M. Janda, B.A., Francesco S. Amodeo, B.S., Ralph Lydic, Ph.D.

Anesthesiology. October 2011: 115(4):836–843

DOI: https://doi.org/10.1097/ALN.0b013e318221fcc9

Published: October 2011

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Articles

Pulmonary Vasoconstrictive and Bronchoconstrictive Responses to Anaphylaxis Are Weakened via β 2 -adrenoceptor Activation by Endogenous Epinephrine in Anesthetized Rats

Wei Zhang, M.Sc., Toshishige Shibamoto, M.D., Ph.D., Yuhichi Kuda, B.Sc., Chieko Ohmukai, B.Sc., Yasutaka Kurata, M.D., Ph.D.

Anesthesiology. March 2011: 114(3):614–623

DOI: https://doi.org/10.1097/ALN.0b013e31820b8d34

Published: March 2011

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Articles

Spinal α2-Adrenoceptor-mediated Analgesia in Neuropathic Pain Reflects Brain-derived Nerve Growth Factor and Changes in Spinal Cholinergic Neuronal Function

Ken-ichiro Hayashida, D.V.M., Ph.D., James C. Eisenach, M.D.

Anesthesiology. August 2010: 113(2):406–412

DOI: https://doi.org/10.1097/ALN.0b013e3181de6d2c

Published: August 2010

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Articles

Involvement of β 3 -Adrenoceptor in Altered β-Adrenergic Response in Senescent Heart: Role of Nitric Oxide Synthase 1–derived Nitric Oxide

Aurélie Birenbaum, M.D., Angela Tesse, Ph.D., Xavier Loyer, Ph.D., Pierre Michelet, M.D., Ph.D., Ramaroson Andriantsitohaina, Ph.D., Christophe Heymes, Ph.D., Bruno Riou, M.D., Ph.D., Julien Amour, M.D., Ph.D.

Anesthesiology. December 2008: 109(6):1045–1053

DOI: https://doi.org/10.1097/ALN.0b013e31818d7e5a

Published: December 2008

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Articles

Differential Effects of α 2 -adrenoceptors in the Modulation of the Thermoregulatory Response in Mice Induced by Meperidine

Jan Höcker, M.D., Andrea Paris, M.D., Jens Scholz, M.D., Peter H. Tonner, M.D., Martin Nielsen, M.S., Berthold Bein, M.D., D.E.A.A.

Anesthesiology. July 2008: 109(1):95–100

DOI: https://doi.org/10.1097/ALN.0b013e31817c02fc

Published: July 2008

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Articles

Dexmedetomidine Increases Hippocampal Phosphorylated Extracellular Signal–regulated Protein Kinase 1 and 2 Content by an α 2 -Adrenoceptor–independent Mechanism: Evidence for the Involvement of Imidazoline I1 Receptors

Souhayl Dahmani, M.D., Ph.D., Andrea Paris, M.D., Virginie Jannier, M.D., Lutz Hein, M.D., Danielle Rouelle, Jens Scholz, M.D., Ph.D., Pierre Gressens, M.D., Ph.D., Jean Mantz, M.D., Ph.D.

Anesthesiology. March 2008: 108(3):457–466

DOI: https://doi.org/10.1097/ALN.0b013e318164ca81

Published: March 2008

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Articles

Adrenergic Receptor Genotype but Not Perioperative Bisoprolol Therapy May Determine Cardiovascular Outcome in At-risk Patients Undergoing Surgery with Spinal Block: The Swiss Beta Blocker in Spinal Anesthesia (BBSA) Study: A Double-blinded, Placebo-controlled, Multicenter Trial with 1-Year Follow-up

Michael Zaugg, M.D., Lukas Bestmann, Ph.D., Johannes Wacker, M.D., Eliana Lucchinetti, Ph.D., Anita Boltres, M.D., Christian Schulz, M.D., Martin Hersberger, Ph.D., Gabriela Kälin, B.Sc., Lukas Furrer, M.D., Christoph Hofer, M.D., Stephan Blumenthal, M.D., Annabelle Müller, Ph.D., Andreas Zollinger, M.D., Donat R. Spahn, M.D., Alain Borgeat, M.D.

Anesthesiology. July 2007: 107(1):33–44

DOI: https://doi.org/10.1097/01.anes.0000267530.62344.a4

Published: July 2007

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Articles

β 2 -Adrenoceptor Genotype Affects Vasopressor Requirements during Spinal Anesthesia for Cesarean Delivery

Richard M. Smiley, M.D., Ph.D., Jean-Louis Blouin, Ph.D., Maria Negron, M.D., Ruth Landau, M.D.

Anesthesiology. April 2006: 104(4):644–650

DOI: https://doi.org/10.1097/00000542-200604000-00006

Published: April 2006

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Articles

Effects of the α 2 -Adrenoceptor Agonist Dexmedetomidine on Bronchoconstriction in Dogs

Harald Groeben, M.D., Wayne Mitzner, Ph.D., Robert H. Brown, M.D., M.P.H.

Anesthesiology. February 2004: 100(2):359–363

DOI: https://doi.org/10.1097/00000542-200402000-00026

Published: February 2004

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Articles

Catecholamine-induced Changes in the Splanchnic Circulation Affecting Systemic Hemodynamics

Simon Gelman, M.D., Ph.D., Phillip S. Mushlin, M.D., Ph.D., Richard B Weiskopf, M.D.

Anesthesiology. February 2004: 100(2):434–439

DOI: https://doi.org/10.1097/00000542-200402000-00036

Published: February 2004

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Articles

Activation of α 2B -Adrenoceptors Mediates the Cardiovascular Effects of Etomidate

Andrea Paris, M.D., Melanie Philipp, Ph.D., Peter H. Tonner, M.D., Markus Steinfath, M.D., Martin Lohse, M.D., Jens Scholz, M.D., Lutz Hein, M.D.

Anesthesiology. October 2003: 99(4):889–895

DOI: https://doi.org/10.1097/00000542-200310000-00022

Published: October 2003

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Articles

Spinal Adrenergic and Cholinergic Receptor Interactions Activated by Clonidine in Postincisional Pain

Frédéric Duflo, M.D., Dawn Conklin, B.S., Xinhui Li, Ph.D., James C. Eisenach, M.D.

Anesthesiology. May 2003: 98(5):1237–1242

DOI: https://doi.org/10.1097/00000542-200305000-00028

Published: May 2003

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Articles

α 2 Adrenoceptor–mediated Presynaptic Inhibition of Primary Afferent Glutamatergic Transmission in Rat Substantia Gelatinosa Neurons

Yasuhiko Kawasaki, M.D., Eiichi Kumamoto, Ph.D., Hidemasa Furue, Ph.D., Megumu Yoshimura, M.D., Ph.D.

Anesthesiology. March 2003: 98(3):682–689

DOI: https://doi.org/10.1097/00000542-200303000-00016

Published: March 2003

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Articles

The α 2 -Adrenoceptor Agonist Dexmedetomidine Converges on an Endogenous Sleep-promoting Pathway to Exert Its Sedative Effects

Laura E. Nelson, B.A., Jun Lu, M.D., Ph.D., Tianzhi Guo, M.D., Clifford B. Saper, M.D., Ph.D., Nicholas P. Franks, Ph.D., Mervyn Maze, M.B., Ch.B., F.R.C.P., F.R.C.A. F.MedSci.

Anesthesiology. February 2003: 98(2):428–436

DOI: https://doi.org/10.1097/00000542-200302000-00024

Published: February 2003

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NARROW

Dexmedetomidine Exerts an Anti-inflammatory Effect via α 2 Adrenoceptors to Prevent Lipopolysaccharide-induced Cognitive Decline in Mice

In Vitro Negative Inotropic Effect of Low Concentrations of Bupivacaine Relates to Diminished Ca 2+ Sensitivity but Not to Ca 2+ Handling or β-Adrenoceptor Signaling

Overexpression of Cyclic Adenosine Monophosphate Effluent Protein MRP4 Induces an Altered Response to β-Adrenergic Stimulation in the Senescent Rat Heart

Interaction of Metabolic and Respiratory Acidosis with α and β-adrenoceptor Stimulation in Rat Myocardium

Ondansetron Reverses Antihypersensitivity from Clonidine in Rats after Peripheral Nerve Injury: Role of γ-Aminobutyric Acid in α2-Adrenoceptor and 5-HT3 Serotonin Receptor Analgesia

Anesthesia Literature Review

Perineural Dexmedetomidine Added to Ropivacaine for Sciatic Nerve Block in Rats Prolongs the Duration of Analgesia by Blocking the Hyperpolarization-activated Cation Current

Pulmonary Vasoconstrictive and Bronchoconstrictive Responses to Anaphylaxis Are Weakened via β 2 -adrenoceptor Activation by Endogenous Epinephrine in Anesthetized Rats

Spinal α2-Adrenoceptor-mediated Analgesia in Neuropathic Pain Reflects Brain-derived Nerve Growth Factor and Changes in Spinal Cholinergic Neuronal Function

Involvement of β 3 -Adrenoceptor in Altered β-Adrenergic Response in Senescent Heart: Role of Nitric Oxide Synthase 1–derived Nitric Oxide

Differential Effects of α 2 -adrenoceptors in the Modulation of the Thermoregulatory Response in Mice Induced by Meperidine

Dexmedetomidine Increases Hippocampal Phosphorylated Extracellular Signal–regulated Protein Kinase 1 and 2 Content by an α 2 -Adrenoceptor–independent Mechanism: Evidence for the Involvement of Imidazoline I1 Receptors

Adrenergic Receptor Genotype but Not Perioperative Bisoprolol Therapy May Determine Cardiovascular Outcome in At-risk Patients Undergoing Surgery with Spinal Block: The Swiss Beta Blocker in Spinal Anesthesia (BBSA) Study: A Double-blinded, Placebo-controlled, Multicenter Trial with 1-Year Follow-up

β 2 -Adrenoceptor Genotype Affects Vasopressor Requirements during Spinal Anesthesia for Cesarean Delivery

Effects of the α 2 -Adrenoceptor Agonist Dexmedetomidine on Bronchoconstriction in Dogs

Catecholamine-induced Changes in the Splanchnic Circulation Affecting Systemic Hemodynamics

Activation of α 2B -Adrenoceptors Mediates the Cardiovascular Effects of Etomidate

Spinal Adrenergic and Cholinergic Receptor Interactions Activated by Clonidine in Postincisional Pain

α 2 Adrenoceptor–mediated Presynaptic Inhibition of Primary Afferent Glutamatergic Transmission in Rat Substantia Gelatinosa Neurons

The α 2 -Adrenoceptor Agonist Dexmedetomidine Converges on an Endogenous Sleep-promoting Pathway to Exert Its Sedative Effects

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