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Evaluation of Biomarkers in Critical Care and Perioperative Medicine: A Clinician’s Overview of Traditional Statistical Methods and Machine Learning Algorithms

Sabri Soussi, M.D., M.Sc., Gary S. Collins, Ph.D., Peter Jüni, M.D., Alexandre Mebazaa, M.D., Ph.D., Etienne Gayat, M.D., Ph.D., Yannick Le Manach, M.D., Ph.D.

Anesthesiology. January 2021: 134(1):15–25

DOI: https://doi.org/10.1097/ALN.0000000000003600

Published: January 2021

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Articles

Of Railroads and Roller Coasters: Considerations for Perioperative Blood Pressure Management?

Yannick Le Manach, M.D., Ph.D., Christian S. Meyhoff, M.D., Ph.D., Gary S. Collins, Ph.D., Eske K. Aasvang, M.D., D.M.Sc., Martin J. London, M.D.

Anesthesiology. September 2020: 133(3):489–492

DOI: https://doi.org/10.1097/ALN.0000000000003446

Published: September 2020

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Articles

One-year Results of a Factorial Randomized Trial of Aspirin versus Placebo and Clonidine versus Placebo in Patients Having Noncardiac Surgery

Anesthesiology. April 2020: 132(4):692–701

DOI: https://doi.org/10.1097/ALN.0000000000003158

Published: April 2020

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Articles

When Large Administrative Databases Provide Less Relevant Information than Randomized Studies

Frédéric Aubrun, M.D., Ph.D., Yannick Le Manach, M.D., Ph.D., Bruno Riou, M.D., Ph.D.

Anesthesiology. March 2019: 130(3):514–515

DOI: https://doi.org/10.1097/ALN.0000000000002569

Published: March 2019

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Articles

Xenon and Cardioprotection: Is This the Light at the End of the Tunnel?

Yannick Le Manach, M.D., Ph.D., Serena Sibilio, M.D., M.S., Richard Whitlock, M.D., Ph.D.

Anesthesiology. December 2017: 127(6):913–914

DOI: https://doi.org/10.1097/ALN.0000000000001874

Published: December 2017

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Articles

Comparison of the Prognostic Significance of Initial Blood Lactate and Base Deficit in Trauma Patients

Mathieu Raux, M.D., Ph.D., Yannick Le Manach, M.D., Ph.D., Tobias Gauss, M.D., Romain Baumgarten, M.D., Sophie Hamada, M.D., Anatole Harrois, M.D., Ph.D., Bruno Riou, M.D., Ph.D., for the TRAUMABASE® Group , Jacques Duranteau, M.D., Ph.D., Olivier Langeron, M.D., Ph.D., Jean Mantz, M.D., Ph.D., Catherine Paugam-Burtz, M.D., Ph.D., Bernard Vigue, M.D.

Anesthesiology. March 2017: 126(3):522–533

DOI: https://doi.org/10.1097/ALN.0000000000001490

Published: March 2017

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Articles

Withholding versus Continuing Angiotensin-converting Enzyme Inhibitors or Angiotensin II Receptor Blockers before Noncardiac Surgery: An Analysis of the Vascular events In noncardiac Surgery patIents cOhort evaluatioN Prospective Cohort

Anesthesiology. January 2017: 126(1):16–27

DOI: https://doi.org/10.1097/ALN.0000000000001404

Published: January 2017

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Yannick Le Manach, M.D., Ph.D., Reitze Rodseth, M.B.Ch.B., Ph.D., Christine Le Bihan-Benjamin, M.D., M.Sc., Bruce Biccard, M.B.Ch.B., Ph.D., Bruno Riou, M.D., Ph.D., P. J. Devereaux, M.D., Ph.D., Paul Landais, M.D., Ph.D., Gary Collins, Ph.D.

Anesthesiology. October 2016: 125(4):816–817

DOI: https://doi.org/10.1097/ALN.0000000000001270

Published: October 2016

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Articles

Current Quality Registries Lack the Accurate Data Needed to Perform Adequate Reliability Adjustments

Ira S. Hofer, M.D., Yannick Le Manach, M.D., Ph.D., Maxime Cannesson, M.D., Ph.D.

Anesthesiology. August 2016: 125(2):422–423

DOI: https://doi.org/10.1097/ALN.0000000000001178

Published: August 2016

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Articles

Preoperative Score to Predict Postoperative Mortality (POSPOM): Derivation and Validation

Yannick Le Manach, M.D., Ph.D., Gary Collins, Ph.D., Reitze Rodseth, M.B.Ch.B., Ph.D., Christine Le Bihan-Benjamin, M.D., M.Sc., Bruce Biccard, M.B.Ch.B., Ph.D., Bruno Riou, M.D., Ph.D., P.J. Devereaux, M.D., Ph.D., Paul Landais, M.D., Ph.D.

Anesthesiology. March 2016: 124(3):570–579

DOI: https://doi.org/10.1097/ALN.0000000000000972

Published: March 2016

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Yannick Le Manach, M.D., Ph.D., Chris Hofer, M.D., Benoit Vallet, M.D., Ph.D., Benoit Tavernier, M.D., Ph.D., Maxime Cannesson, M.D., Ph.D.

Anesthesiology. September 2013: 119(3):726–727

DOI: https://doi.org/10.1097/ALN.0b013e31829e094e

Published: September 2013

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Articles

Postoperative B-type Natriuretic Peptide for Prediction of Major Cardiac Events in Patients Undergoing Noncardiac Surgery: Systematic Review and Individual Patient Meta-analysis

Reitze N. Rodseth, M.B.Ch.B., F.C.A., M.Med., Bruce M. Biccard, M.B.Ch.B., F.C.A., Ph.D., Rong Chu, M.Sc., Ph.D., Giovana A. Lurati Buse, M.D., Lehana Thabane, Ph.D., Ameet Bakhai, M.B.B.S., M.D., F.R.C.P., M.E.S.H., F.E.S.C., Daniel Bolliger, M.D., Lucio Cagini, M.D., Thomas J. Cahill, M.A., M.B.B.S., M.R.C.P., Daniela Cardinale, M.D., Ph.D., F.E.S.C., Carol P. W. Chong, M.B.B.S., F.R.A.C.P., M.D., Miłosław Cnotliwy, M.D., Ph.D., Salvatore Di Somma, M.D., Ph.D., René Fahrner, M.D., Wen K. Lim, M.D., M.B.B.S., F.R.A.C.P., Elisabeth Mahla, M.D., Yannick Le Manach, M.D., Ph.D., Ramaswamy Manikandan, M.D., Wook B. Pyun, M.D., Sriram Rajagopalan, M.D., F.R.C.S., Milan Radovic´, M.D., Ph.D., Robert C. Schutt, M.D., Daniel I. Sessler, M.D., Stuart Suttie, M.B.Ch.B., M.D., F.R.C.S.Ed., Thuvaraha Vanniyasingam, B.Sc., Marek Waliszek, M.D., Ph.D., P. J. Devereaux, M.D., Ph.D.

Anesthesiology. August 2013: 119(2):270–283

DOI: https://doi.org/10.1097/ALN.0b013e31829083f1

Published: August 2013

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Articles

δ Opioid Receptor Antagonists: Do They Buy Time for Traumatic Hemorrhagic Shock Patients?

Jacques Duranteau, M.D., Ph.D., Yannick Le Manach, M.D., Ph.D.

Anesthesiology. August 2013: 119(2):253–255

DOI: https://doi.org/10.1097/ALN.0b013e31829b3853

Published: August 2013

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Articles

Multivariable Risk Prediction Models: It’s All about the Performance

Gary Collins, Ph.D., Yannick Le Manach, M.D., Ph.D.

Anesthesiology. June 2013: 118(6):1252–1253

DOI: https://doi.org/10.1097/ALN.0b013e31828e13e9

Published: June 2013

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In Reply:

Maxime Cannesson, M.D., Ph.D., Yannick Le Manach, M.D., Ph.D.

Anesthesiology. June 2013: 118(6):1481

DOI: https://doi.org/10.1097/ALN.0b013e3182910492

Published: June 2013

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Articles

Erythrocyte Transfusion: Remedy or Poison?

Yannick Le Manach, M.D., Ph.D., Summer Syed, B.Sc., M.D., M.Sc., F.R.C.P.C.

Anesthesiology. December 2012: 117(6):1153–1155

DOI: https://doi.org/10.1097/ALN.0b013e318271608b

Published: December 2012

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Articles

Can Changes in Arterial Pressure be Used to Detect Changes in Cardiac Output during Volume Expansion in the Perioperative Period?

Yannick Le Manach, M.D., Ph.D., Christoph K. Hofer, M.D., Ph.D., Jean-Jacques Lehot, M.D., Ph.D., Benoît Vallet, M.D., Ph.D., Jean-Pierre Goarin, M.D., Benoît Tavernier, M.D., Ph.D., Maxime Cannesson, M.D., Ph.D.

Anesthesiology. December 2012: 117(6):1165–1174

DOI: https://doi.org/10.1097/ALN.0b013e318275561d

Published: December 2012

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Articles

Prediction of Difficult Tracheal Intubation: Time for a Paradigm Change

Olivier Langeron, M.D., Ph.D., Philippe Cuvillon, M.D., Cristina Ibanez-Esteve, M.D., François Lenfant, M.D., Ph.D., Bruno Riou, M.D., Ph.D., Yannick Le Manach, M.D., Ph.D.

Anesthesiology. December 2012: 117(6):1223–1233

DOI: https://doi.org/10.1097/ALN.0b013e31827537cb

Published: December 2012

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Articles

Noninvasive Hemodynamic Monitoring: No High Heels on the Farm; No Clogs to the Opera

Maxime Cannesson, M.D., Ph.D., Yannick Le Manach, M.D., Ph.D.

Anesthesiology. November 2012: 117(5):937–939

DOI: https://doi.org/10.1097/ALN.0b013e3182700ad6

Published: November 2012

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Articles

In Reply

Maxime Cannesson, M.D., Ph.D., Yannick Le Manach, M.D., Ph.D., Benoit Vallet, M.D., Ph.D., Benoit Tavernier, M.D., Ph.D.

Anesthesiology. March 2012: 116(3):741–743

DOI: https://doi.org/10.1097/ALN.0b013e3182475838

Published: March 2012

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NARROW

Evaluation of Biomarkers in Critical Care and Perioperative Medicine: A Clinician’s Overview of Traditional Statistical Methods and Machine Learning Algorithms

Of Railroads and Roller Coasters: Considerations for Perioperative Blood Pressure Management?

One-year Results of a Factorial Randomized Trial of Aspirin versus Placebo and Clonidine versus Placebo in Patients Having Noncardiac Surgery

When Large Administrative Databases Provide Less Relevant Information than Randomized Studies

Xenon and Cardioprotection: Is This the Light at the End of the Tunnel?

Comparison of the Prognostic Significance of Initial Blood Lactate and Base Deficit in Trauma Patients

Withholding versus Continuing Angiotensin-converting Enzyme Inhibitors or Angiotensin II Receptor Blockers before Noncardiac Surgery: An Analysis of the Vascular events In noncardiac Surgery patIents cOhort evaluatioN Prospective Cohort

In Reply

Current Quality Registries Lack the Accurate Data Needed to Perform Adequate Reliability Adjustments

Preoperative Score to Predict Postoperative Mortality (POSPOM): Derivation and Validation

In Reply

Postoperative B-type Natriuretic Peptide for Prediction of Major Cardiac Events in Patients Undergoing Noncardiac Surgery: Systematic Review and Individual Patient Meta-analysis

δ Opioid Receptor Antagonists: Do They Buy Time for Traumatic Hemorrhagic Shock Patients?

Multivariable Risk Prediction Models: It’s All about the Performance

In Reply:

Erythrocyte Transfusion: Remedy or Poison?

Can Changes in Arterial Pressure be Used to Detect Changes in Cardiac Output during Volume Expansion in the Perioperative Period?

Prediction of Difficult Tracheal Intubation: Time for a Paradigm Change

Noninvasive Hemodynamic Monitoring: No High Heels on the Farm; No Clogs to the Opera

In Reply

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