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Malignant Hyperthermia in North America: Genetic Screening of the Three Hot Spots in the Type I Ryanodine Receptor Gene

Yoshitatsu Sei, M.D., Ph.D., Nyamkhishig N. Sambuughin, Ph.D., Edward J. Davis, B.S., Daniel Sachs, Phil B. Cuenca, M.D., Barbara W. Brandom, M.D., Timothy Tautz, M.D., Henry Rosenberg, M.D., Thomas E. Nelson, Ph.D., Sheila M. Muldoon, M.D.

Anesthesiology. October 2004: 101(4):824–830

DOI: https://doi.org/10.1097/00000542-200410000-00005

Published: October 2004

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Genetic Testing for Malignant Hyperthermia in North America

Thomas E. Nelson, Ph.D., Henry Rosenberg, M.D., Sheila M. Muldoon, M.D.

Anesthesiology. February 2004: 100(2):212–214

DOI: https://doi.org/10.1097/00000542-200402000-00004

Published: February 2004

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Autosomal Dominant Canine Malignant Hyperthermia Is Caused by a Mutation in the Gene Encoding the Skeletal Muscle Calcium Release Channel ( RYR1 )

Monica C. Roberts, B.S., James R. Mickelson, Ph.D., Edward E. Patterson, D.V.M., Thomas E. Nelson, Ph.D., P. Jane Armstrong, M.S., D.V.M., David B. Brunson, D.V.M., M.S., Kirk Hogan, M.D.

Anesthesiology. September 2001: 95(3):716–725

DOI: https://doi.org/10.1097/00000542-200109000-00026

Published: September 2001

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North American Malignant Hyperthermia Population: Screening of the Ryanodine Receptor Gene and Identification of Novel Mutations

Nyamkhishig Sambuughin, Ph.D., Yoshitatsu Sei, M.D., Ph.D., Kathleen L. Gallagher, M.S., Hadley W. Wyre, Daniel Madsen, M.D., Thomas E. Nelson, Ph.D., Jeffrey E. Fletcher, Ph.D., Henry Rosenberg, M.D., Sheila M. Muldoon, M.D.

Anesthesiology. September 2001: 95(3):594–599

DOI: https://doi.org/10.1097/00000542-200109000-00009

Published: September 2001

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Room 302, 10/17/2000 2: 00 PM - 3: 30 PM (PD) Comparative Cardiac Effect of R(+) and S(-) Bupivacaine with S(-) Ropivacaine : A-131

Roberto T. Sudo, M.D., Ph.D., Margarete M. Trachez, M.D., Ph.D., Gisele Zapata-Sudo, M.D., Ph.D., Thomas E. Nelson, Ph.D.

Anesthesiology. September 2000: 93(3A):A–131

DOI: https://doi.org/10.1097/00000542-200009001-00131

Published: September 2000

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Room E, 10/17/2000 2: 00 PM - 4: 00 PM (PS) Deletion in RyR1 Gene Associated with MH and with Abnormal Electrically Evoked Twitch Tension : A-103

In Vitro Thomas E. Nelson, Ph.D., Nyamkhishg Sambuughin, Ph.D.

Anesthesiology. September 2000: 93(3A):A–103

DOI: https://doi.org/10.1097/00000542-200009001-00103

Published: September 2000

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Articles

A Clinical Grading Scale to Predict Malignant Hyperthermia Susceptibility

Marilyn Green Larach, M.D., F.A.A.P., A Russell Localio, M.P.H., M.S., Gregory C. Allen, M.D., F.R.C.P.C., Michael A. Denborough, M.D., D.Phil., F Richard Ellis, Ph.D., F.R.C.Anaes., Gerald A. Gronert, M.D., Richard F. Kaplan, M.D., Sheila M. Muldoon, M.D., Thomas E. Nelson, Ph.D., Helle Ørding, M.D., Henry Rosenberg, M.D., Barbara E. Waud, M.D., Denise J. Wedel, M.D.

Anesthesiology. April 1994: 80(4):771–779

DOI: https://doi.org/10.1097/00000542-199404000-00008

Published: April 1994

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Halothane Effects on Human Malignant Hyperthermia Skeletal Muscle Single Calcium-release Channels in Planar Lipid Bilayers

Thomas E. Nelson, Ph.D.

Anesthesiology. April 1992: 76(4):588–595

DOI: https://doi.org/10.1097/00000542-199204000-00016

Published: April 1992

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Porcine Malignant Hyperthermia: Critical Temperatures for In Vivoand In VitroResponses

Thomas E. Nelson, Ph.D.

Anesthesiology. September 1990: 73(3):449–454

DOI: https://doi.org/10.1097/00000542-199009000-00013

Published: September 1990

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Ca 2+ Uptake and Ca 2+ Release by Skeletal Muscle Sarcoplasmic Reticulum: Differing Sensitivity to Inhalational Anesthetics

Thomas E. Nelson, Ph.D., T. Sweo, B.A.

Anesthesiology. October 1988: 69(4):571–577

DOI: https://doi.org/10.1097/00000542-198810000-00018

Published: October 1988

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Articles

Prophylactic and Therapeutic Doses of Dantrolene for Malignant Hyperthermia

E. H. Flewellen, M.D., Thomas E. Nelson, Ph.D.

Anesthesiology. October 1984: 61(4):477

DOI: https://doi.org/10.1097/00000542-198410000-00023

Published: October 1984

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Articles

Rationale for Dantrolene vs. Procainamide for Treatment of Malignant Hyperthermia

Thomas E. Nelson, Ph.D., Eugene H. Flewellen, M.D.

Anesthesiology. February 1979: 50(2):118–122

DOI: https://doi.org/10.1097/00000542-197902000-00008

Published: February 1979

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NARROW

Malignant Hyperthermia in North America: Genetic Screening of the Three Hot Spots in the Type I Ryanodine Receptor Gene

Genetic Testing for Malignant Hyperthermia in North America

Autosomal Dominant Canine Malignant Hyperthermia Is Caused by a Mutation in the Gene Encoding the Skeletal Muscle Calcium Release Channel ( RYR1 )

North American Malignant Hyperthermia Population: Screening of the Ryanodine Receptor Gene and Identification of Novel Mutations

Room 302, 10/17/2000 2: 00 PM - 3: 30 PM (PD) Comparative Cardiac Effect of R(+) and S(-) Bupivacaine with S(-) Ropivacaine : A-131

Room E, 10/17/2000 2: 00 PM - 4: 00 PM (PS) Deletion in RyR1 Gene Associated with MH and with Abnormal Electrically Evoked Twitch Tension : A-103

A Clinical Grading Scale to Predict Malignant Hyperthermia Susceptibility

Halothane Effects on Human Malignant Hyperthermia Skeletal Muscle Single Calcium-release Channels in Planar Lipid Bilayers

Porcine Malignant Hyperthermia: Critical Temperatures for In Vivoand In VitroResponses

Ca 2+ Uptake and Ca 2+ Release by Skeletal Muscle Sarcoplasmic Reticulum: Differing Sensitivity to Inhalational Anesthetics

Prophylactic and Therapeutic Doses of Dantrolene for Malignant Hyperthermia

Rationale for Dantrolene vs. Procainamide for Treatment of Malignant Hyperthermia

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