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Anesthetic Management Using Multiple Closed-loop Systems and Delayed Neurocognitive Recovery: A Randomized Controlled Trial

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Alexandre Joosten, M.D., Ph.D., Joseph Rinehart, M.D., Aurélie Bardaji, M.D., Philippe Van der Linden, M.D., Ph.D., Vincent Jame, M.D., Luc Van Obbergh, M.D., Ph.D., Brenton Alexander, M.D., Maxime Cannesson, M.D., Ph.D., Susana Vacas, M.D., Ph.D., Ngai Liu, M.D., Ph.D., Hichem Slama, Ph.D., Luc Barvais, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. February 2020: 132(2):253–266
DOI: https://doi.org/10.1097/ALN.0000000000003014
Published: February 2020
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Dexmedetomidine Prevents Cognitive Decline by Enhancing Resolution of High Mobility Group Box 1 Protein–induced Inflammation through a Vagomimetic Action in Mice

Jun Hu, M.D., Susana Vacas, M.D., Ph.D., Xiaomei Feng, M.D., Ph.D., David Lutrin, M.D., Yosuke Uchida, M.D., Ph.D., Ieng Kit Lai, B.S., Mervyn Maze, M.B.Ch.B.
Publication: Anesthesiology
Anesthesiology. May 2018: 128(5):921–931
DOI: https://doi.org/10.1097/ALN.0000000000002038
Published: May 2018
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In Reply

Susana Vacas, M.D., Ph.D., Vincent Degos, M.D., Ph.D., Mervyn Maze, M.B., Ch.B.
Publication: Anesthesiology
Anesthesiology. December 2014: 121(6):1353–1354
DOI: https://doi.org/10.1097/ALN.0000000000000453
Published: December 2014
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High-mobility Group Box 1 Protein Initiates Postoperative Cognitive Decline by Engaging Bone Marrow–derived Macrophages

Susana Vacas, M.D., Vincent Degos, M.D., Ph.D., Kevin J. Tracey, M.D., Mervyn Maze, M.B., Ch.B.
Publication: Anesthesiology
Anesthesiology. May 2014: 120(5):1160–1167
DOI: https://doi.org/10.1097/ALN.0000000000000045
Published: May 2014
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Enzyme-inducing Anticonvulsants Increase Plasma Clearance of Dexmedetomidine: A Pharmacokinetic and Pharmacodynamic Study

Alana M. Flexman, M.D., Harvey Wong, Ph.D., K. Wayne Riggs, Ph.D., Tina Shih, M.D., Paul A. Garcia, M.D., Susana Vacas, M.D., Pekka O. Talke, M.D.
Publication: Anesthesiology
Anesthesiology. May 2014: 120(5):1118–1125
DOI: https://doi.org/10.1097/ALN.0000000000000141
Published: May 2014
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Bone Fracture Exacerbates Murine Ischemic Cerebral Injury

Vincent Degos, M.D., Ph.D., Mervyn Maze, M.B., Ch.B., Susana Vacas, M.D., Jan Hirsch, M.D., Yi Guo, M.D., Fanxia Shen, M.D., Kristine Jun, B.S., Nico van Rooijen, Ph.D., Pierre Gressens, M.D., Ph.D., William L. Young, M.D., Hua Su, M.D.
Publication: Anesthesiology
Anesthesiology. June 2013: 118(6):1362–1372
DOI: https://doi.org/10.1097/ALN.0b013e31828c23f8
Published: June 2013
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Surgery Results in Exaggerated and Persistent Cognitive Decline in a Rat Model of the Metabolic Syndrome

Xiaomei Feng, M.D., Ph.D., Vincent Degos, M.D., Ph.D., Lauren G. Koch, Ph.D., Steven L. Britton, Ph.D., Yinggang Zhu, M.D., Susana Vacas, M.D., Niccolò Terrando, B.Sc., Ph.D., Jeffrey Nelson, M.S., Xiao Su, M.D., Ph.D., Mervyn Maze, M.B., Ch.B.
Publication: Anesthesiology
Anesthesiology. May 2013: 118(5):1098–1105
DOI: https://doi.org/10.1097/ALN.0b013e318286d0c9
Published: May 2013
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Depletion of Bone Marrow–derived Macrophages Perturbs the Innate Immune Response to Surgery and Reduces Postoperative Memory Dysfunction

Vincent Degos, M.D., Ph.D., Susana Vacas, M.D., Zhenying Han, M.D., Nico van Rooijen, Ph.D., Pierre Gressens, M.D., Ph.D., Hua Su, M.D., William L. Young, M.D., Mervyn Maze, M.B., Ch.B.
Publication: Anesthesiology
Anesthesiology. March 2013: 118(3):527–536
DOI: https://doi.org/10.1097/ALN.0b013e3182834d94
Published: March 2013
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