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Articles

Central Sensitization, N -methyl-d-aspartate Receptors, and Human Experimental Pain Models: Bridging the Gap between Target Discovery and Drug Development

Srinivasa N. Raja, M.D., Eellan Sivanesan, M.D., Yun Guan, M.D., Ph.D.

Anesthesiology. August 2019: 131(2):233–235

https://doi.org/10.1097/ALN.0000000000002808

Published: August 2019

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Articles

Supraspinal Mechanisms of Spinal Cord Stimulation for Modulation of Pain: Five Decades of Research and Prospects for the Future

Eellan Sivanesan, M.D., Dermot P. Maher, M.D., M.S., Srinivasa N. Raja, M.D., Bengt Linderoth, M.D., Ph.D., Yun Guan, M.D., Ph.D.

Anesthesiology. April 2019: 130(4):651–665

https://doi.org/10.1097/ALN.0000000000002353

Published: April 2019

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Articles

Peripherally Acting μ-Opioid Receptor Agonists Attenuate Ongoing Pain-associated Behavior and Spontaneous Neuronal Activity after Nerve Injury in Rats

Vinod Tiwari, Ph.D., Michael Anderson, M.S., Fei Yang, Ph.D., Vineeta Tiwari, M.Pharm., Qin Zheng, Ph.D., Shao-Qiu He, Ph.D., Tong Zhang, M.D., Bin Shu, M.D., Xueming Chen, M.D., Shaness A. Grenald, Ph.D., Kimberly E. Stephens, Ph.D., Zhiyong Chen, Ph.D., Xinzhong Dong, Ph.D., Srinivasa N. Raja, M.D., Yun Guan, M.D., Ph.D.

Anesthesiology. June 2018: 128(6):1220–1236

https://doi.org/10.1097/ALN.0000000000002191

Published: June 2018

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Articles

Overexpression of µ-Opioid Receptors in Peripheral Afferents, but Not in Combination with Enkephalin, Decreases Neuropathic Pain Behavior and Enhances Opioid Analgesia in Mouse

Amanda H. Klein, Ph.D., M.S., Husam K. Mohammad, Ph.D., R.Ph., Rabiah Ali, M.D., Brad Peper, D.M.D., Steven P. Wilson, Ph.D., Srinivasa N. Raja, M.D., Matthias Ringkamp, M.D., Ph.D., Sarah Sweitzer, Ph.D.

Anesthesiology. May 2018: 128(5):967–983

https://doi.org/10.1097/ALN.0000000000002063

Published: May 2018

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Articles

Activation of Peripheral μ-opioid Receptors by Dermorphin [d-Arg2, Lys4] (1–4) Amide Leads to Modality-preferred Inhibition of Neuropathic Pain

Vinod Tiwari, Ph.D., Fei Yang, Ph.D., Shao-Qiu He, Ph.D., Ronen Shechter, M.D., Chen Zhang, M.D., Bin Shu, M.D., Tong Zhang, M.D., Vineeta Tiwari, M.Pharm., Yun Wang, M.D., Xinzhong Dong, Ph.D., Yun Guan, M.D., Ph.D., Srinivasa N. Raja, M.D.

Anesthesiology. March 2016: 124(3):706–720

https://doi.org/10.1097/ALN.0000000000000993

Published: March 2016

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Articles

Balance in Opioid Prescription during Pregnancy

Pamela Flood, M.D., Srinivasa N. Raja, M.D.

Anesthesiology. May 2014: 120(5):1063–1064

https://doi.org/10.1097/ALN.0000000000000173

Published: May 2014

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Articles

Conventional and Kilohertz-frequency Spinal Cord Stimulation Produces Intensity- and Frequency-dependent Inhibition of Mechanical Hypersensitivity in a Rat Model of Neuropathic Pain

Ronen Shechter, M.D., Fei Yang, Ph.D., Qian Xu, Ph.D., Yong-Kwan Cheong, M.D., Ph.D., Shao-Qiu He, Ph.D., Andrei Sdrulla, M.D., Ph.D., Alene F. Carteret, M.S., Paul W. Wacnik, Ph.D., Xinzhong Dong, Ph.D., Richard A. Meyer, M.S., Srinivasa N. Raja, M.D., Yun Guan, M.D., Ph.D.

Anesthesiology. August 2013: 119(2):422–432

https://doi.org/10.1097/ALN.0b013e31829bd9e2

Published: August 2013

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Articles

Prevention of Chronic Postsurgical Pain: The Ongoing Search for the Holy Grail of Anesthesiology

Steven P. Cohen, M.D., Srinivasa N. Raja, M.D.

Anesthesiology. February 2013: 118(2):241–243

https://doi.org/10.1097/ALN.0b013e31827d4129

Published: February 2013

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Articles

Testing the Link between Sympathetic Efferent and Sensory Afferent Fibers in Neuropathic Pain

Srinivasa N. Raja, M.D., Rolf-Detlef Treede, M.D., Ph.D., David S. Warner, M.D.

Anesthesiology. July 2012: 117(1):173–177

https://doi.org/10.1097/ALN.0b013e31825adb2b

Published: July 2012

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Articles

A Peripheral Adrenoceptor-mediated Sympathetic Mechanism Can Transform Stress-induced Analgesia into Hyperalgesia

John E. Donello, Ph.D., Yun Guan, M.D., Ph.D., Mingting Tian, M.S., Cynthia V. Cheevers, B.S., Miguel Alcantara, B.S., Sara Cabrera, M.S., Srinivasa N. Raja, M.D., Daniel W. Gil, Ph.D.

Anesthesiology. June 2011: 114(6):1403–1416

https://doi.org/10.1097/ALN.0b013e31821c3878

Published: June 2011

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Articles

Anesthesiologists as Genetic Counselors?

Frank H. Lee, M.D., Srinivasa N. Raja, M.D.

Anesthesiology. April 2011: 114(4):1003–1004

https://doi.org/10.1097/ALN.0b013e31820f20b4

Published: April 2011

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Articles

Spinal Cord Stimulation-induced Analgesia: Electrical Stimulation of Dorsal Column and Dorsal Roots Attenuates Dorsal Horn Neuronal Excitability in Neuropathic Rats

Yun Guan, M.D., Ph.D., Paul W. Wacnik, Ph.D., Fei Yang, Ph.D., Alene F. Carteret, M.S., Chih-Yang Chung, M.D., Richard A. Meyer, M.S., Srinivasa N. Raja, M.D.

Anesthesiology. December 2010: 113(6):1392–1405

https://doi.org/10.1097/ALN.0b013e3181fcd95c

Published: December 2010

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Articles

A Role for Acid-sensing Ion Channel 3, but Not Acid-sensing Ion Channel 2, in Sensing Dynamic Mechanical Stimuli

Jasenka Borzan, Ph.D., Chengshui Zhao, Ph.D., Richard A. Meyer, M.S., Srinivasa N. Raja, M.D.

Anesthesiology. September 2010: 113(3):647–654

https://doi.org/10.1097/ALN.0b013e3181eaa58a

Published: September 2010

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Articles

Predicting Postoperative Pain Based on Preoperative Pain Perception: Are We Doing Better Than the Weatherman?

Srinivasa N. Raja, M.D., Troels S. Jensen, M.D., Ph.D.

Anesthesiology. June 2010: 112(6):1311–1312

https://doi.org/10.1097/ALN.0b013e3181dcd5cc

Published: June 2010

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Articles

Preventing Chronic Postsurgical Pain: How Much of a Difference Makes a Difference?

Robert H. Dworkin, Ph.D., Michael P. McDermott, Ph.D., Srinivasa N. Raja, M.D.

Anesthesiology. March 2010: 112(3):516–518

https://doi.org/10.1097/ALN.0b013e3181cf4253

Published: March 2010

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Articles

Morphine versus Mexiletine for Treatment of Postamputation Pain: A Randomized, Placebo-controlled, Crossover Trial

Christopher L. Wu, M.D., Shefali Agarwal, M.B.B.S., M.P.H., Prabhav K. Tella, M.B.B.S., M.P.H., Brendan Klick, M.S., Michael R. Clark, M.D., M.P.H., Jennifer A. Haythornthwaite, Ph.D., Mitchell B. Max, M.D., Srinivasa N. Raja, M.D.

Anesthesiology. August 2008: 109(2):289–296

https://doi.org/10.1097/ALN.0b013e31817f4523

Published: August 2008

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Articles

Pathogenesis, Diagnosis, and Treatment of Lumbar Zygapophysial (Facet) Joint Pain

Steven P. Cohen, M.D., Srinivasa N. Raja, M.D.

Anesthesiology. March 2007: 106(3):591–614

https://doi.org/10.1097/00000542-200703000-00024

Published: March 2007

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Articles

Methoxyflurane Revisited: Tale of an Anesthetic from Cradle to Grave

Richard I. Mazze, M.D., Srinivasa N. Raja, M.D.

Anesthesiology. October 2006: 105(4):843–846

https://doi.org/10.1097/00000542-200610000-00031

Published: October 2006

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Articles

Myocardial Ischemia Revisited

Stephen Slogoff, M.D., Arthur S. Keats, M.D., Srinivasa N. Raja, M.D.

Anesthesiology. July 2006: 105(1):214–216

https://doi.org/10.1097/00000542-200607000-00032

Published: July 2006

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Articles

Copper Kettle Revisited

Lucien E. Morris, M.D., F.R.C.A, F.F.A R.AC.S. (Hon.), D.Sc., Srinivasa N. Raja, M.D.

Anesthesiology. April 2006: 104(4):881–884

https://doi.org/10.1097/00000542-200604000-00034

Published: April 2006

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NARROW

Central Sensitization, N -methyl-d-aspartate Receptors, and Human Experimental Pain Models: Bridging the Gap between Target Discovery and Drug Development

Supraspinal Mechanisms of Spinal Cord Stimulation for Modulation of Pain: Five Decades of Research and Prospects for the Future

Peripherally Acting μ-Opioid Receptor Agonists Attenuate Ongoing Pain-associated Behavior and Spontaneous Neuronal Activity after Nerve Injury in Rats

Overexpression of µ-Opioid Receptors in Peripheral Afferents, but Not in Combination with Enkephalin, Decreases Neuropathic Pain Behavior and Enhances Opioid Analgesia in Mouse

Activation of Peripheral μ-opioid Receptors by Dermorphin [d-Arg2, Lys4] (1–4) Amide Leads to Modality-preferred Inhibition of Neuropathic Pain

Balance in Opioid Prescription during Pregnancy

Conventional and Kilohertz-frequency Spinal Cord Stimulation Produces Intensity- and Frequency-dependent Inhibition of Mechanical Hypersensitivity in a Rat Model of Neuropathic Pain

Prevention of Chronic Postsurgical Pain: The Ongoing Search for the Holy Grail of Anesthesiology

Testing the Link between Sympathetic Efferent and Sensory Afferent Fibers in Neuropathic Pain

A Peripheral Adrenoceptor-mediated Sympathetic Mechanism Can Transform Stress-induced Analgesia into Hyperalgesia

Anesthesiologists as Genetic Counselors?

Spinal Cord Stimulation-induced Analgesia: Electrical Stimulation of Dorsal Column and Dorsal Roots Attenuates Dorsal Horn Neuronal Excitability in Neuropathic Rats

A Role for Acid-sensing Ion Channel 3, but Not Acid-sensing Ion Channel 2, in Sensing Dynamic Mechanical Stimuli

Predicting Postoperative Pain Based on Preoperative Pain Perception: Are We Doing Better Than the Weatherman?

Preventing Chronic Postsurgical Pain: How Much of a Difference Makes a Difference?

Morphine versus Mexiletine for Treatment of Postamputation Pain: A Randomized, Placebo-controlled, Crossover Trial

Pathogenesis, Diagnosis, and Treatment of Lumbar Zygapophysial (Facet) Joint Pain

Methoxyflurane Revisited: Tale of an Anesthetic from Cradle to Grave

Myocardial Ischemia Revisited

Copper Kettle Revisited

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