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Robert D. Sanders, B.Sc., M.B.B.S., Ph.D., F.R.C.A., Recipient of the 2020 James E. Cottrell, M.D., Presidential Scholar Award

Robert A. Pearce, M.D., Ph.D., Mervyn Maze, M.B.Ch.B., F.R.C.P., F.R.C.A., F.Med.Sci.

Anesthesiology. October 2020: 133(4):720–723

DOI: https://doi.org/10.1097/ALN.0000000000003512

Published: October 2020

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Dexmedetomidine Exerts an Anti-inflammatory Effect via α 2 Adrenoceptors to Prevent Lipopolysaccharide-induced Cognitive Decline in Mice

Rong Li, M.D., Ieng K. Lai, B.S., Jonathan Z. Pan, M.D., Ph.D., Pengbo Zhang, M.D., Ph.D., Mervyn Maze, M.B., Ch.B.

Anesthesiology. August 2020: 133(2):393–407

DOI: https://doi.org/10.1097/ALN.0000000000003390

Published: August 2020

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Perioperative Neurocognitive Disorder: State of the Preclinical Science

Roderic G. Eckenhoff, M.D., Mervyn Maze, M.B., C.H.B., Zhongcong Xie, M.D., Ph.D., Deborah J. Culley, M.D., Sarah J. Goodlin, M.D., Zhiyi Zuo, M.D., Ph.D., Huafeng Wei, M.D., Ph.D., Robert A. Whittington, M.D., Niccolò Terrando, Ph.D., Beverley A. Orser, M.D., Ph.D., Maryellen F. Eckenhoff, Ph.D.

Anesthesiology. January 2020: 132(1):55–68

DOI: https://doi.org/10.1097/ALN.0000000000002956

Published: January 2020

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Dexmedetomidine Prevents Cognitive Decline by Enhancing Resolution of High Mobility Group Box 1 Protein–induced Inflammation through a Vagomimetic Action in Mice

Jun Hu, M.D., Susana Vacas, M.D., Ph.D., Xiaomei Feng, M.D., Ph.D., David Lutrin, M.D., Yosuke Uchida, M.D., Ph.D., Ieng Kit Lai, B.S., Mervyn Maze, M.B.Ch.B.

Anesthesiology. May 2018: 128(5):921–931

DOI: https://doi.org/10.1097/ALN.0000000000002038

Published: May 2018

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From Bench to Bedside and Back Again: A Personal Journey with Dexmedetomidine

Mervyn Maze, M.B., Ch.B.

Anesthesiology. September 2016: 125(3):590–594

DOI: https://doi.org/10.1097/ALN.0000000000001214

Published: September 2016

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In Reply

Susana Vacas, M.D., Ph.D., Vincent Degos, M.D., Ph.D., Mervyn Maze, M.B., Ch.B.

Anesthesiology. December 2014: 121(6):1353–1354

DOI: https://doi.org/10.1097/ALN.0000000000000453

Published: December 2014

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High-mobility Group Box 1 Protein Initiates Postoperative Cognitive Decline by Engaging Bone Marrow–derived Macrophages

Susana Vacas, M.D., Vincent Degos, M.D., Ph.D., Kevin J. Tracey, M.D., Mervyn Maze, M.B., Ch.B.

Anesthesiology. May 2014: 120(5):1160–1167

DOI: https://doi.org/10.1097/ALN.0000000000000045

Published: May 2014

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Articles

Bone Fracture Exacerbates Murine Ischemic Cerebral Injury

Vincent Degos, M.D., Ph.D., Mervyn Maze, M.B., Ch.B., Susana Vacas, M.D., Jan Hirsch, M.D., Yi Guo, M.D., Fanxia Shen, M.D., Kristine Jun, B.S., Nico van Rooijen, Ph.D., Pierre Gressens, M.D., Ph.D., William L. Young, M.D., Hua Su, M.D.

Anesthesiology. June 2013: 118(6):1362–1372

DOI: https://doi.org/10.1097/ALN.0b013e31828c23f8

Published: June 2013

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Articles

Surgery Results in Exaggerated and Persistent Cognitive Decline in a Rat Model of the Metabolic Syndrome

Xiaomei Feng, M.D., Ph.D., Vincent Degos, M.D., Ph.D., Lauren G. Koch, Ph.D., Steven L. Britton, Ph.D., Yinggang Zhu, M.D., Susana Vacas, M.D., Niccolò Terrando, B.Sc., Ph.D., Jeffrey Nelson, M.S., Xiao Su, M.D., Ph.D., Mervyn Maze, M.B., Ch.B.

Anesthesiology. May 2013: 118(5):1098–1105

DOI: https://doi.org/10.1097/ALN.0b013e318286d0c9

Published: May 2013

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Depletion of Bone Marrow–derived Macrophages Perturbs the Innate Immune Response to Surgery and Reduces Postoperative Memory Dysfunction

Vincent Degos, M.D., Ph.D., Susana Vacas, M.D., Zhenying Han, M.D., Nico van Rooijen, Ph.D., Pierre Gressens, M.D., Ph.D., Hua Su, M.D., William L. Young, M.D., Mervyn Maze, M.B., Ch.B.

Anesthesiology. March 2013: 118(3):527–536

DOI: https://doi.org/10.1097/ALN.0b013e3182834d94

Published: March 2013

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Articles

Xenon Neuroprotection in Experimental Stroke: Interactions with Hypothermia and Intracerebral Hemorrhage

Siyuan P. Sheng, Beilei Lei, M.D., Ph.D., Michael L. James, M.D., Christopher D. Lascola, M.D., Ph.D., Talaignair N. Venkatraman, Ph.D., Jin Yong Jung, M.D., Ph.D., Mervyn Maze, M.B., Ch.B., Nicholas P. Franks, Ph.D., Robert D. Pearlstein, Ph.D., Huaxin Sheng, M.D., David S. Warner, M.D.

Anesthesiology. December 2012: 117(6):1262–1275

DOI: https://doi.org/10.1097/ALN.0b013e3182746b81

Published: December 2012

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Noradrenergic Trespass in Anesthetic and Sedative States

Robert D. Sanders, B.Sc., M.B.B.S., Ph.D., F.R.C.A., Mervyn Maze, M.B.Ch.B., F.R.C.P., F.R.C.A., F.Med.Sci.

Anesthesiology. November 2012: 117(5):945–947

DOI: https://doi.org/10.1097/ALN.0b013e3182700c93

Published: November 2012

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Heat Shock Protein 72 Overexpression Prevents Early Postoperative Memory Decline after Orthopedic Surgery under General Anesthesia in Mice

Marcela P. Vizcaychipi, M.B.B.S., M.D., E.D.I.C.M., F.R.C.A., Lijun Xu, M.D., George E. Barreto, Ph.D., Daqing Ma, M.D., Ph.D., Mervyn Maze, M.B.Ch.B., F.R.C.A., F.R.C.P., Rona G. Giffard, Ph.D., M.D.

Anesthesiology. April 2011: 114(4):891–900

DOI: https://doi.org/10.1097/ALN.0b013e31820ad3ce

Published: April 2011

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Xenon Pretreatment Attenuates Anesthetic-induced Apoptosis in the Developing Brain in Comparison with Nitrous Oxide and Hypoxia

Yi Shu, B.Sc., Shivali M. Patel, M.B.B.S., B.Sc., Chen Pac-Soo, M.B.Ch.B., M.D., F.R.C.A., António Rei Fidalgo, B.Sc., M.Sc., Yanjie Wan, M.D., Mervyn Maze, M.B.B.S., F.R.C.A., Daqing Ma, M.D., Ph.D.

Anesthesiology. August 2010: 113(2):360–368

DOI: https://doi.org/10.1097/ALN.0b013e3181d960d7

Published: August 2010

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Preconditioning and Postinsult Therapies for Perinatal Hypoxic–Ischemic Injury at Term

Robert D. Sanders, B.Sc., M.B.B.S., F.R.C.A., Helen J. Manning, M.B., D.F.F.P., M.R.C.O.G., Nicola J. Robertson, M.B.Ch.B., Ph.D., F.R.C.P.C.H., Daqing Ma, M.D., Ph.D., A. David Edwards, M.B.Ch.B., F.R.C.P.C.H., F.Med.Sci., Henrik Hagberg, M.D., Ph.D., Mervyn Maze, M.B.Ch.B., F.R.C.P., F.R.C.A., F.Med.Sci.

Anesthesiology. July 2010: 113(1):233–249

DOI: https://doi.org/10.1097/ALN.0b013e3181dc1b84

Published: July 2010

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Articles

Noble Gas Xenon Is a Novel Adenosine Triphosphate-sensitive Potassium Channel Opener

Carsten Bantel, M.D., Ph.D., F.R.C.A., F.F.P.M.R.C.A., Mervyn Maze, M.B., Ch.B., F.R.C.A., F.R.C.P., F.Med.Sci., Stefan Trapp, Ph.D.

Anesthesiology. March 2010: 112(3):623–630

DOI: https://doi.org/10.1097/ALN.0b013e3181cf894a

Published: March 2010

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Articles

Role of Transient Receptor Potential and Acid-sensing Ion Channels in Peripheral Inflammatory Pain

John P. M. White, LL.D., Mario Cibelli, M.D., Antonio Rei Fidalgo, M.Sc., Cleoper C. Paule, B.Sc., Faruq Noormohamed, M.Sc., Laszlo Urban, Ph.D., Mervyn Maze, M.B., B.Ch., Istvan Nagy, Ph.D.

Anesthesiology. March 2010: 112(3):729–741

DOI: https://doi.org/10.1097/ALN.0b013e3181ca3179

Published: March 2010

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Articles

Does Correcting the Numbers Improve Long-term Outcome?

Robert D. Sanders, B.Sc., M.B.B.S., F.R.C.A., Mervyn Maze, M.B., Ch.B., F.R.C.P., F.R.C.A., F.Med.Sci.

Anesthesiology. September 2009: 111(3):475–477

DOI: https://doi.org/10.1097/ALN.0b013e3181b31cb0

Published: September 2009

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Articles

Dexmedetomidine Attenuates Isoflurane-induced Neurocognitive Impairment in Neonatal Rats

Robert D. Sanders, B.Sc., M.B.B.S., F.R.C.A., Jing Xu, M.D., Yi Shu, B.Sc., Adam Januszewski, B.Sc., M.B.B.S., Sunil Halder, B.Sc., M.B.B.S., Antonio Fidalgo, M.Sc., Pamela Sun, B.Sc., Mahmuda Hossain, Ph.D., Daqing Ma, M.D., Ph.D., Mervyn Maze, M.B., Ch.B., F.R.C.P., F.R.C.A., F.Med.Sci.

Anesthesiology. May 2009: 110(5):1077–1085

DOI: https://doi.org/10.1097/ALN.0b013e31819daedd

Published: May 2009

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Articles

Neuronal Preconditioning by Inhalational Anesthetics: Evidence for the Role of Plasmalemmal Adenosine Triphosphate–sensitive Potassium Channels

Carsten Bantel, M.D., F.R.C.A., Mervyn Maze, M.B., Ch.B., F.R.C.A., F.R.C.P., F.Med.Sci., Stefan Trapp, Ph.D.

Anesthesiology. May 2009: 110(5):986–995

DOI: https://doi.org/10.1097/ALN.0b013e31819dadc7

Published: May 2009

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NARROW

Robert D. Sanders, B.Sc., M.B.B.S., Ph.D., F.R.C.A., Recipient of the 2020 James E. Cottrell, M.D., Presidential Scholar Award

Dexmedetomidine Exerts an Anti-inflammatory Effect via α 2 Adrenoceptors to Prevent Lipopolysaccharide-induced Cognitive Decline in Mice

Perioperative Neurocognitive Disorder: State of the Preclinical Science

Dexmedetomidine Prevents Cognitive Decline by Enhancing Resolution of High Mobility Group Box 1 Protein–induced Inflammation through a Vagomimetic Action in Mice

From Bench to Bedside and Back Again: A Personal Journey with Dexmedetomidine

In Reply

High-mobility Group Box 1 Protein Initiates Postoperative Cognitive Decline by Engaging Bone Marrow–derived Macrophages

Bone Fracture Exacerbates Murine Ischemic Cerebral Injury

Surgery Results in Exaggerated and Persistent Cognitive Decline in a Rat Model of the Metabolic Syndrome

Depletion of Bone Marrow–derived Macrophages Perturbs the Innate Immune Response to Surgery and Reduces Postoperative Memory Dysfunction

Xenon Neuroprotection in Experimental Stroke: Interactions with Hypothermia and Intracerebral Hemorrhage

Noradrenergic Trespass in Anesthetic and Sedative States

Heat Shock Protein 72 Overexpression Prevents Early Postoperative Memory Decline after Orthopedic Surgery under General Anesthesia in Mice

Xenon Pretreatment Attenuates Anesthetic-induced Apoptosis in the Developing Brain in Comparison with Nitrous Oxide and Hypoxia

Preconditioning and Postinsult Therapies for Perinatal Hypoxic–Ischemic Injury at Term

Noble Gas Xenon Is a Novel Adenosine Triphosphate-sensitive Potassium Channel Opener

Role of Transient Receptor Potential and Acid-sensing Ion Channels in Peripheral Inflammatory Pain

Does Correcting the Numbers Improve Long-term Outcome?

Dexmedetomidine Attenuates Isoflurane-induced Neurocognitive Impairment in Neonatal Rats

Neuronal Preconditioning by Inhalational Anesthetics: Evidence for the Role of Plasmalemmal Adenosine Triphosphate–sensitive Potassium Channels

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