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Immunologic Consequences of Hypoxia during Critical Illness

Harmke D. Kiers, M.D., Gert-Jan Scheffer, M.D., Ph.D., Johannes G. van der Hoeven, M.D., Ph.D., Holger K. Eltzschig, M.D., Ph.D., Peter Pickkers, M.D., Ph.D., Matthijs Kox, Ph.D.

Anesthesiology. July 2016: 125(1):237–249

DOI: https://doi.org/10.1097/ALN.0000000000001163

Published: July 2016

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Articles

Toll-like Receptor 4 Signaling in Ventilator-induced Diaphragm Atrophy

Willem-Jan M. Schellekens, M.D., Hieronymus W. H. van Hees, Ph.D., Michiel Vaneker, M.D., Ph.D., Marianne Linkels, M.S., P. N. Richard Dekhuijzen, M.D., Ph.D., Gert Jan Scheffer, M.D., Ph.D., Johannes G. van der Hoeven, M.D., Ph.D., Leo M. A. Heunks, M.D., Ph.D.

Anesthesiology. August 2012: 117(2):329–338

DOI: https://doi.org/10.1097/ALN.0b013e3182608cc0

Published: August 2012

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Articles

Hemorrhagic Shock-induced Endothelial Cell Activation in a Spontaneous Breathing and a Mechanical Ventilation Hemorrhagic Shock Model Is Induced by a Proinflammatory Response and Not by Hypoxia

Matijs van Meurs, M.D., Ph.D., Francis M. Wulfert, M.D., Rianne M. Jongman, B.Sc., Martin Schipper, B.Sc., Martin C. Houwertjes, Michiel Vaneker, M.D., Ph.D., Gert Jan Scheffer, M.D., Ph.D., Luc J. Teppema, Ph.D., Leon P. H. J. Aarts, M.D., Ph.D., Peter Heeringa, Ph.D., Jan G. Zijlstra, M.D., Ph.D., Grietje Molema, Ph.D.

Anesthesiology. September 2011: 115(3):474–482

DOI: https://doi.org/10.1097/ALN.0b013e318229a640

Published: September 2011

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Articles

Mechanical Ventilation Induces a Toll/Interleukin-1 Receptor Domain-containing Adapter-inducing Interferon β–dependent Inflammatory Response in Healthy Mice

Michiel Vaneker, M.D., Leo M. A. Heunks, M.D., Ph.D., Leo A. Joosten, Ph.D., Hieronymus W. H. van Hees, Ph.D., Dirk G. Snijdelaar, M.D., Ph.D., Feico J. Halbertsma, M.D., Ph.D., Jan van Egmond, Ph.D., Mihai G. Netea, M.D., Ph.D., Johannes G. van der Hoeven, M.D., Ph.D., Gert Jan Scheffer, M.D., Ph.D.

Anesthesiology. October 2009: 111(4):836–843

DOI: https://doi.org/10.1097/ALN.0b013e3181b76499

Published: October 2009

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Articles

Low-tidal-volume Mechanical Ventilation Induces a Toll-like Receptor 4–dependent Inflammatory Response in Healthy Mice

Michiel Vaneker, M.D., Leo A. Joosten, Ph.D., Leo M. A. Heunks, M.D., Ph.D., Dirk G. Snijdelaar, M.D., Ph.D., Feico J. Halbertsma, M.D., Jan van Egmond, Ph.D., Mihai G. Netea, M.D., Ph.D., Johannes G. van der Hoeven, M.D., Ph.D., Gert Jan Scheffer, M.D., Ph.D.

Anesthesiology. September 2008: 109(3):465–472

DOI: https://doi.org/10.1097/ALN.0b013e318182aef1

Published: September 2008

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Articles

Mechanical Ventilation in Healthy Mice Induces Reversible Pulmonary and Systemic Cytokine Elevation with Preserved Alveolar Integrity: An In VivoModel Using Clinical Relevant Ventilation Settings

Michiel Vaneker, M.D., Feico J. Halbertsma, M.D., Jan van Egmond, Ph.D., Mihai G. Netea, M.D., Ph.D., Henry B. Dijkman, Ph.D., Dirk G. Snijdelaar, M.D., Ph.D., Leo A. Joosten, Ph.D., Johannes G. van der Hoeven, M.D., Ph.D., Gert Jan Scheffer, M.D., Ph.D.

Anesthesiology. September 2007: 107(3):419–426

DOI: https://doi.org/10.1097/01.anes.0000278908.22686.01

Published: September 2007

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Room F, 10/17/2000 9: 00 AM - 11: 00 AM (PS) Improvement of Responsiveness to Nitric Oxide in Endotoxin-Challenged Rat Pulmonary Arteries : A-442

Christa Boer, Harro A. Piepot, PhD, Gert Jan Scheffer, MD, PhD, Pieter Sipkema, PhD, Jaap J. de Lange, MD, PhD

Anesthesiology. September 2000: 93(3A):A–442

DOI: https://doi.org/10.1097/00000542-200009001-00442

Published: September 2000

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NARROW

Immunologic Consequences of Hypoxia during Critical Illness

Toll-like Receptor 4 Signaling in Ventilator-induced Diaphragm Atrophy

Hemorrhagic Shock-induced Endothelial Cell Activation in a Spontaneous Breathing and a Mechanical Ventilation Hemorrhagic Shock Model Is Induced by a Proinflammatory Response and Not by Hypoxia

Mechanical Ventilation Induces a Toll/Interleukin-1 Receptor Domain-containing Adapter-inducing Interferon β–dependent Inflammatory Response in Healthy Mice

Low-tidal-volume Mechanical Ventilation Induces a Toll-like Receptor 4–dependent Inflammatory Response in Healthy Mice

Mechanical Ventilation in Healthy Mice Induces Reversible Pulmonary and Systemic Cytokine Elevation with Preserved Alveolar Integrity: An In VivoModel Using Clinical Relevant Ventilation Settings

Room F, 10/17/2000 9: 00 AM - 11: 00 AM (PS) Improvement of Responsiveness to Nitric Oxide in Endotoxin-Challenged Rat Pulmonary Arteries : A-442

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Immunologic Consequences of Hypoxia during Critical Illness

Toll-like Receptor 4 Signaling in Ventilator-induced Diaphragm Atrophy

Hemorrhagic Shock-induced Endothelial Cell Activation in a Spontaneous Breathing and a Mechanical Ventilation Hemorrhagic Shock Model Is Induced by a Proinflammatory Response and Not by Hypoxia

Mechanical Ventilation Induces a Toll/Interleukin-1 Receptor Domain-containing Adapter-inducing Interferon β–dependent Inflammatory Response in Healthy Mice

Low-tidal-volume Mechanical Ventilation Induces a Toll-like Receptor 4–dependent Inflammatory Response in Healthy Mice

Mechanical Ventilation in Healthy Mice Induces Reversible Pulmonary and Systemic Cytokine Elevation with Preserved Alveolar Integrity: An In VivoModel Using Clinical Relevant Ventilation Settings

Room F, 10/17/2000 9: 00 AM - 11: 00 AM (PS) Improvement of Responsiveness to Nitric Oxide in Endotoxin-Challenged Rat Pulmonary Arteries : A-442

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