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Early Phase Pharmacokinetics but Not Pharmacodynamics Are Influenced by Propofol Infusion Rate

Kenichi Masui, M.D., Ph.D., Marimo Kira, D.D.S., Tomiei Kazama, M.D., Ph.D., Satoshi Hagihira, M.D., Ph.D., Eric P. Mortier, M.D., D.Sc., Michel M. R. F. Struys, M.D., Ph.D.

Anesthesiology. October 2009: 111(4):805–817

https://doi.org/10.1097/ALN.0b013e3181b799c1

Published: October 2009

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Articles

Response Surface Modeling of the Interaction between Propofol and Sevoflurane

Peter M. Schumacher, M.Sc., Ph.D., Jan Dossche, M.D., Eric P. Mortier, M.D., D.Sc., Martin Luginbuehl, M.D., Ph.D., Thomas W. Bouillon, M.D., Michel M. R. F. Struys, M.D., Ph.D.

Anesthesiology. October 2009: 111(4):790–804

https://doi.org/10.1097/ALN.0b013e3181b799ef

Published: October 2009

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Articles

Influence of Administration Rate on Propofol Plasma–Effect Site Equilibration

Michel M. R. F. Struys, M.D., Ph.D., Marc J. Coppens, M.D., Nikolaas De Neve, M.D., Eric P. Mortier, M.D., D.Sc., Anthony G. Doufas, M.D., Ph.D., Jan F. P. Van Bocxlaer, Pha., Ph.D., Steven L. Shafer, M.D.

Anesthesiology. September 2007: 107(3):386–396

https://doi.org/10.1097/01.anes.0000278902.15505.f8

Published: September 2007

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Articles

The Effects of Ketamine and Rocuronium on the A-Line® Auditory Evoked Potential Index, Bispectral Index, and Spectral Entropy Monitor during Steady State Propofol and Remifentanil Anesthesia

Hugo E. M. Vereecke, M.D., Ann L. Vanluchene, M.D., Eric P. Mortier, M.D., D.Sc., Karel Everaert, M.D., Ph.D., Michel M. R. F. Struys, M.D., Ph.D.

Anesthesiology. December 2006: 105(6):1122–1134

https://doi.org/10.1097/00000542-200612000-00012

Published: December 2006

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Articles

Comparison of Three Disposable Extraglottic Airway Devices in Spontaneously Breathing Adults: The LMA-Unique™, the Soft Seal Laryngeal Mask, and the Cobra Perilaryngeal Airway

André van Zundert, M.D., Ph.D., F.R.C.A., Baha Al-Shaikh, F.C.A.R.C.S.I., F.R.C.A., Joseph Brimacombe, M.D., M.B., Ch.B., F.R.C.A., Jurgen Koster, M.D., Dick Koning, M.D., Eric P. Mortier, M.D., Ph.D.

Anesthesiology. June 2006: 104(6):1165–1169

https://doi.org/10.1097/00000542-200606000-00010

Published: June 2006

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Articles

AQUAVAN® Injection, a Water-soluble Prodrug of Propofol, as a Bolus Injection: A Phase I Dose-escalation Comparison with DIPRIVAN® (Part 1): Pharmacokinetics: Retracted

Ekaterina Gibiansky, Ph.D., Michel M. R. F. Struys, M.D., Ph.D., Leonid Gibiansky, Ph.D., Ann L. G. Vanluchene, M.D., James Vornov, M.D., Ph.D., Eric P. Mortier, M.D., D.Sc., Eric Burak, Ph.D., Luc Van Bortel, M.D., Ph.D.

Anesthesiology. October 2005: 103(4):718–729

https://doi.org/10.1097/00000542-200510000-00010

Published: October 2005

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Articles

AQUAVAN® Injection, a Water-soluble Prodrug of Propofol, as a Bolus Injection: A Phase I Dose-escalation Comparison with DIPRIVAN® (Part 2): Pharmacodynamics and Safety: Retracted

Michel M. R. F. Struys, M.D., Ph.D., Ann L. G. Vanluchene, M.D., Ekaterina Gibiansky, Ph.D., Leonid Gibiansky, Ph.D., James Vornov, M.D., Ph.D., Eric P. Mortier, M.D., D.Sc., Luc Van Bortel, M.D., Ph.D.

Anesthesiology. October 2005: 103(4):730–743

https://doi.org/10.1097/00000542-200510000-00011

Published: October 2005

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Articles

New Composite Index Based on Midlatency Auditory Evoked Potential and Electroencephalographic Parameters to Optimize Correlation with Propofol Effect Site Concentration: Comparison with Bispectral Index and Solitary Used Fast Extracting Auditory Evoked Potential Index

Hugo E. M. Vereecke, M.D., Pablo Martinez Vasquez, M.Sc., Erik Weber Jensen, M.Sc., Ph.D., Olivier Thas, M.Sc., Ph.D., Rudy Vandenbroecke, M.D., Ph.D., Eric P. Mortier, M.D., D.Sc., Michel M. R. F. Struys, M.D., Ph.D.

Anesthesiology. September 2005: 103(3):500–507

https://doi.org/10.1097/00000542-200509000-00012

Published: September 2005

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Articles

Spectral Entropy as an Electroencephalographic Measure of Anesthetic Drug Effect: A Comparison with Bispectral Index and Processed Midlatency Auditory Evoked Response

Ann L.G. Vanluchene, M.D., Hugo Vereecke, M.D., Olivier Thas, M.Sc., Ph.D., Eric P. Mortier, M.D., D.Sc., Steven L. Shafer, M.D., Michel M.R.F. Struys, M.D., Ph.D.

Anesthesiology. July 2004: 101(1):34–42

https://doi.org/10.1097/00000542-200407000-00008

Published: July 2004

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Articles

Performance Evaluation of Two Published Closed-loop Control Systems Using Bispectral Index Monitoring: A Simulation Study

Michel M. R. F. Struys, M.D., Ph.D., Tom De Smet, M.Sc., Scott Greenwald, Ph.D., Anthony R. Absalom, M.B.Ch.B., F.R.C.A., Servaas Bingé, B.Sc., Eric P. Mortier, M.D., D.Sc.

Anesthesiology. March 2004: 100(3):640–647

https://doi.org/10.1097/00000542-200403000-00026

Published: March 2004

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Articles

Ability of the Bispectral Index, Autoregressive Modelling with Exogenous Input-derived Auditory Evoked Potentials, and Predicted Propofol Concentrations to Measure Patient Responsiveness during Anesthesia with Propofol and Remifentanil

Michel M. R. F. Struys, M.D., Ph.D., Hugo Vereecke, M.D., Annelies Moerman, M.D., Erik Weber Jensen, M.Sc., Ph.D., David Verhaeghen, M.D., Nicolaas De Neve, M.D., Frank J. E. Dumortier, M.D., Eric P. Mortier, M.D., D.Sc.

Anesthesiology. October 2003: 99(4):802–812

https://doi.org/10.1097/00000542-200310000-00010

Published: October 2003

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Articles

Depth of Anesthesia Monitors: Status Quo: In Reply:—

Michel M.R.F. Struys, M.D., Ph.D., Eric P. Mortier, MD, D.Sc.

Anesthesiology. March 2003: 98(3):795

https://doi.org/10.1097/00000542-200303000-00039

Published: March 2003

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Articles

Performance of the ARX-derived Auditory Evoked Potential Index as an Indicator of Anesthetic Depth: A Comparison with Bispectral Index and Hemodynamic Measures during Propofol Administration

Michel M. R. F. Struys, M.D., Ph.D., Erik Weber Jensen, Ph.D., Warren Smith, Ph.D., N. Ty Smith, M.D., Ira Rampil, M.S., M.D., Frank J. E. Dumortier, M.D., Christel Mestach, M.D., Eric P. Mortier, M.D., D.Sc.

Anesthesiology. April 2002: 96(4):803–816

https://doi.org/10.1097/00000542-200204000-00006

Published: April 2002

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Articles

Only Carbon Dioxide Absorbents Free of Both NaOH and KOH Do Not Generate Compound A during In Vitro Closed-system Sevoflurane: Evaluation of Five Absorbents

Linda F. M. Versichelen, M.D., Marie-Paule L. A. Bouche, Pha., Georges Rolly, M.D., Ph.D., Jan F. P. Van Bocxlaer, Pha., Ph.D., Michel M. R. F. Struys, M.D., Ph.D., André P. De Leenheer, Pha., Ph.D., Eric P. Mortier, M.D., D.Sc.

Anesthesiology. September 2001: 95(3):750–755

https://doi.org/10.1097/00000542-200109000-00030

Published: September 2001

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Articles

Comparison of Closed-loop Controlled Administration of Propofol Using Bispectral Index as the Controlled Variable versus “Standard Practice” Controlled Administration

Michel M. R. F. Struys, M.D., Ph.D., Tom De Smet, M.Sc., Linda F. M. Versichelen, M.D., Stijn Van de Velde, M.B., Rudy Van den Broecke, M.D., Eric P. Mortier, M.D., D.Sc.

Anesthesiology. July 2001: 95(1):6–17

https://doi.org/10.1097/00000542-200107000-00007

Published: July 2001

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Articles

In Vitro Compound A Formation in a Computer-controlled Closed-circuit Anesthetic Apparatus: Comparison with a Classical Valve Circuit

Linda F. M. Versichelen, M.D., Georges Rolly, M.D., Ph.D., Marie-Paule L. A. Bouche, Pha., Jan F. P. Van Bocxlaer, Pha., Ph.D., Michel M. R. F. Struys, M.D., Ph.D., Catherine Van der herten, André P. De Leenheer, Pha., Ph.D., Eric P. Mortier, M.D., D.Sc.

Anesthesiology. October 2000: 93(4):1064–1068

https://doi.org/10.1097/00000542-200010000-00030

Published: October 2000

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Articles

Room C, 10/16/2000 9: 00 AM - 11: 00 AM (PS) Accuracy of Closed-Loop Administration of Propofol Using BIS and a Patient-Individualized, Model-Based Algorithm : A-314

Michel M.R.F. Struys, MD, PhD, Tom De Smet, M. Sc, Stijn Van de Velde, B.Sc, Linda F.M. Versichelen, MD, Eric P. Mortier, MD D Sc

Anesthesiology. September 2000: 93(3A):A–314

https://doi.org/10.1097/00000542-200009001-00314

Published: September 2000

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Articles

Room A, 10/17/2000 9: 00 AM - 11: 00 AM (PS) No Compound A Formation during In Vitro Closed Circuit Sevoflurane Administration and Amsorb R as New CO 2 Absorbent : A-571

Georges Rolly, PhD, Linda F.M. Versichelen, MD, Michel M.R.F. Struys, PhD, Marie Paule L.A. Bouche, Pha, Eric P. Mortier, DSc

Anesthesiology. September 2000: 93(3A):A–571

https://doi.org/10.1097/00000542-200009001-00571

Published: September 2000

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Articles

Room A, 10/17/2000 9: 00 AM - 11: 00 AM (PS) No Comp A Formation during In Vitro Closed Circuit Sevoflurane Administration and Lithium Hydroxide as CO 2 Absorbent : A-577

Linda F.M. Versichelen, MD, Georges Rolly, PhD, Michel M.R.F. Struys, PhD, Marie Paule L.A. Bouche, Pha, Eric P. Mortier, DSc

Anesthesiology. September 2000: 93(3A):A–577

https://doi.org/10.1097/00000542-200009001-00577

Published: September 2000

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Articles

Comparison of Plasma Compartment versus Two Methods for Effect Compartment–controlled Target-controlled Infusion for Propofol

Michel M. R. F. Struys, M.D., Ph.D., Tom De Smet, M.Sc., Birgit Depoorter, M.D., Linda F. M. Versichelen, M.D., Eric P. Mortier, M.D., D.Sc., Frank J. E. Dumortier, M.D., Steven L. Shafer, M.D., Georges Rolly, M.D., Ph.D.

Anesthesiology. February 2000: 92(2):399

https://doi.org/10.1097/00000542-200002000-00021

Published: February 2000

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NARROW

Early Phase Pharmacokinetics but Not Pharmacodynamics Are Influenced by Propofol Infusion Rate

Response Surface Modeling of the Interaction between Propofol and Sevoflurane

Influence of Administration Rate on Propofol Plasma–Effect Site Equilibration

The Effects of Ketamine and Rocuronium on the A-Line® Auditory Evoked Potential Index, Bispectral Index, and Spectral Entropy Monitor during Steady State Propofol and Remifentanil Anesthesia

Comparison of Three Disposable Extraglottic Airway Devices in Spontaneously Breathing Adults: The LMA-Unique™, the Soft Seal Laryngeal Mask, and the Cobra Perilaryngeal Airway

AQUAVAN® Injection, a Water-soluble Prodrug of Propofol, as a Bolus Injection: A Phase I Dose-escalation Comparison with DIPRIVAN® (Part 1): Pharmacokinetics: Retracted

AQUAVAN® Injection, a Water-soluble Prodrug of Propofol, as a Bolus Injection: A Phase I Dose-escalation Comparison with DIPRIVAN® (Part 2): Pharmacodynamics and Safety: Retracted

New Composite Index Based on Midlatency Auditory Evoked Potential and Electroencephalographic Parameters to Optimize Correlation with Propofol Effect Site Concentration: Comparison with Bispectral Index and Solitary Used Fast Extracting Auditory Evoked Potential Index

Spectral Entropy as an Electroencephalographic Measure of Anesthetic Drug Effect: A Comparison with Bispectral Index and Processed Midlatency Auditory Evoked Response

Performance Evaluation of Two Published Closed-loop Control Systems Using Bispectral Index Monitoring: A Simulation Study

Ability of the Bispectral Index, Autoregressive Modelling with Exogenous Input-derived Auditory Evoked Potentials, and Predicted Propofol Concentrations to Measure Patient Responsiveness during Anesthesia with Propofol and Remifentanil

Depth of Anesthesia Monitors: Status Quo: In Reply:—

Performance of the ARX-derived Auditory Evoked Potential Index as an Indicator of Anesthetic Depth: A Comparison with Bispectral Index and Hemodynamic Measures during Propofol Administration

Only Carbon Dioxide Absorbents Free of Both NaOH and KOH Do Not Generate Compound A during In Vitro Closed-system Sevoflurane: Evaluation of Five Absorbents

Comparison of Closed-loop Controlled Administration of Propofol Using Bispectral Index as the Controlled Variable versus “Standard Practice” Controlled Administration

In Vitro Compound A Formation in a Computer-controlled Closed-circuit Anesthetic Apparatus: Comparison with a Classical Valve Circuit

Room C, 10/16/2000 9: 00 AM - 11: 00 AM (PS) Accuracy of Closed-Loop Administration of Propofol Using BIS and a Patient-Individualized, Model-Based Algorithm : A-314

Room A, 10/17/2000 9: 00 AM - 11: 00 AM (PS) No Compound A Formation during In Vitro Closed Circuit Sevoflurane Administration and Amsorb R as New CO 2 Absorbent : A-571

Room A, 10/17/2000 9: 00 AM - 11: 00 AM (PS) No Comp A Formation during In Vitro Closed Circuit Sevoflurane Administration and Lithium Hydroxide as CO 2 Absorbent : A-577

Comparison of Plasma Compartment versus Two Methods for Effect Compartment–controlled Target-controlled Infusion for Propofol

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