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Articles

Anesthesia and Developing Brains: Unanswered Questions and Proposed Paths Forward

Caleb Ing, M.D., M.S., David O. Warner, M.D., Lena S. Sun, M.D., Randall P. Flick, M.D., M.P.H., Andrew J. Davidson, M.B.B.S., M.D., F.A.N.Z.C.A., F.A.H.M.S., Laszlo Vutskits, M.D., Ph.D., Mary Ellen McCann, M.D., James O’Leary, M.D., David C. Bellinger, Ph.D., M.Sc., Virginia Rauh, Sc.D., Beverley A. Orser, M.D., Ph.D., F.R.C.P.C., Santhanam Suresh, M.D., Dean B. Andropoulos, M.D., M.H.C.M.

Anesthesiology. March 2022: 136(3):500–512

https://doi.org/10.1097/ALN.0000000000004116

Published: March 2022

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Articles

2020 Severinghaus Lecture on Translational Science: Reply

Beverley A. Orser, M.D., Ph.D., F.R.C.P.C., F.C.A.H.S., F.R.S.C.

Anesthesiology. January 2022: 136(1):247

https://doi.org/10.1097/ALN.0000000000004023

Published: January 2022

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Articles

Anesthesiology: Resetting Our Sights on Long-term Outcomes: The 2020 John W. Severinghaus Lecture on Translational Science

Beverley A. Orser, M.D., Ph.D., F.R.C.P.C., F.C.A.H.S., F.R.S.C.

Anesthesiology. July 2021: 135(1):18–30

https://doi.org/10.1097/ALN.0000000000003798

Published: July 2021

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Articles

Perioperative Neurocognitive Disorder: State of the Preclinical Science

Roderic G. Eckenhoff, M.D., Mervyn Maze, M.B., C.H.B., Zhongcong Xie, M.D., Ph.D., Deborah J. Culley, M.D., Sarah J. Goodlin, M.D., Zhiyi Zuo, M.D., Ph.D., Huafeng Wei, M.D., Ph.D., Robert A. Whittington, M.D., Niccolò Terrando, Ph.D., Beverley A. Orser, M.D., Ph.D., Maryellen F. Eckenhoff, Ph.D.

Anesthesiology. January 2020: 132(1):55–68

https://doi.org/10.1097/ALN.0000000000002956

Published: January 2020

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Articles

Musings from an Unlikely Clinician–Scientist: 2018 American Society of Anesthesiologists Excellence in Research Award

Beverley A. Orser, M.D., Ph.D.

Anesthesiology. October 2019: 131(4):795–800

https://doi.org/10.1097/ALN.0000000000002881

Published: October 2019

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Articles

In Memoriam: Brian Kavanagh, 1962 to 2019

Beverley A. Orser, M.D., Ph.D., Laurent Brochard, M.D., Ph.D.

Anesthesiology. October 2019: 131(4):759–761

https://doi.org/10.1097/ALN.0000000000002944

Published: October 2019

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Articles

GABA A Receptor Theory of Perioperative Neurocognitive Disorders

Beverley A. Orser, M.D., Ph.D., Dian-Shi Wang, M.D., Ph.D.

Anesthesiology. April 2019: 130(4):618–619

https://doi.org/10.1097/ALN.0000000000002562

Published: April 2019

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Articles

Dexmedetomidine Prevents Excessive γ-Aminobutyric Acid Type A Receptor Function after Anesthesia

Dian-Shi Wang, M.D., Ph.D., Kirusanthy Kaneshwaran, M.Sc., Gang Lei, M.Sc., M.D., Fariya Mostafa, M.Sc., Junhui Wang, M.D., Ph.D., Irene Lecker, Ph.D., Sinziana Avramescu, M.D., Ph.D., Yu-Feng Xie, M.D., Ph.D., Nathan K. Chan, B.Sc., Alejandro Fernandez-Escobar, M.D., Junsung Woo, Ph.D., Darren Chan, B.Sc., Amy J. Ramsey, Ph.D., Jeremy M. Sivak, Ph.D., C. Justin Lee, Ph.D., Robert P. Bonin, Ph.D., Beverley A. Orser, M.D., Ph.D.

Anesthesiology. September 2018: 129(3):477–489

https://doi.org/10.1097/ALN.0000000000002311

Published: September 2018

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Articles

High Concentrations of Tranexamic Acid Inhibit Ionotropic Glutamate Receptors

Irene Lecker, Ph.D., Dian-Shi Wang, M.D., Ph.D., Kirusanthy Kaneshwaran, B.S., C. David Mazer, M.D., Beverley A. Orser, M.D., Ph.D.

Anesthesiology. July 2017: 127(1):89–97

https://doi.org/10.1097/ALN.0000000000001665

Published: July 2017

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Articles

Ketamine Increases the Function of γ-Aminobutyric Acid Type A Receptors in Hippocampal and Cortical Neurons

Dian-Shi Wang, M.D., Ph.D., Antonello Penna, M.D., Ph.D., Beverley A. Orser, M.D., Ph.D.

Anesthesiology. April 2017: 126(4):666–677

https://doi.org/10.1097/ALN.0000000000001483

Published: April 2017

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Articles

In Reply

Sinziana Avramescu, M.D., Ph.D., Dian-Shi Wang, M.D., Ph.D., Richard L. Horner, Ph.D., Beverley A. Orser, M.D., Ph.D.

Anesthesiology. September 2016: 125(3):604–605

https://doi.org/10.1097/ALN.0000000000001206

Published: September 2016

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Articles

Inflammation Increases Neuronal Sensitivity to General Anesthetics

Sinziana Avramescu, M.D., Ph.D., Dian-Shi Wang, M.D., Ph.D., Irene Lecker, Ph.D., William T. H. To, M.Sc., Antonello Penna, M.D., Ph.D., Paul D. Whissell, Ph.D., Lia Mesbah-Oskui, M.Sc., Richard L. Horner, Ph.D., Beverley A. Orser, M.D., Ph.D.

Anesthesiology. February 2016: 124(2):417–427

https://doi.org/10.1097/ALN.0000000000000943

Published: February 2016

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Articles

Perioperative Medication Errors: Building Safer Systems

Beverley A. Orser, M.D., Ph.D., David U, B.Sc.Phm., M.Sc.Phm., Michael R. Cohen, M.S., Sc.D. (hon.), D.P.S. (hon.)

Anesthesiology. January 2016: 124(1):1–3

https://doi.org/10.1097/ALN.0000000000000905

Published: January 2016

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Articles

Isoflurane Regulates Atypical Type-A γ-Aminobutyric Acid Receptors in Alveolar Type II Epithelial Cells

Yun-Yan Xiang, M.D., Ph.D., Xuanmao Chen, Ph.D., Jingxin Li, M.D., Ph.D., Shuanglian Wang, M.D., Ph.D., Gil Faclier, M.D., F.R.C.P.C., John F. MacDonald, Ph.D., James C. Hogg, M.D., Ph.D., F.R.C.P.C., Beverley A. Orser, M.D., Ph.D., F.R.C.P.C., Wei-Yang Lu, M.D., Ph.D.

Anesthesiology. May 2013: 118(5):1065–1075

https://doi.org/10.1097/ALN.0b013e31828e180e

Published: May 2013

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Articles

Intraoperative Awareness: From Neurobiology to Clinical Practice

George A. Mashour, M.D., Ph.D., Beverley A. Orser, M.D., Ph.D., Michael S. Avidan, M.B., B.Ch., David S. Warner, M.D.

Anesthesiology. May 2011: 114(5):1218–1233

https://doi.org/10.1097/ALN.0b013e31820fc9b6

Published: May 2011

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Articles

Short-term Memory Impairment after Isoflurane in Mice Is Prevented by the α5 γ-Aminobutyric Acid Type A Receptor Inverse Agonist L-655,708

Bechara J. Saab, Ph.D., Ashley J. B. MacLean, B.Sc., Marijana Kanisek, M.Sc., Agnieszka A. Zurek, B.Sc., Loren J. Martin, Ph.D., John C. Roder, Ph.D., Beverley A. Orser, Ph.D., M.D.

Anesthesiology. November 2010: 113(5):1061–1071

https://doi.org/10.1097/ALN.0b013e3181f56228

Published: November 2010

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Articles

Etomidate Targets α 5 γ-Aminobutyric Acid Subtype A Receptors to Regulate Synaptic Plasticity and Memory Blockade

Loren J. Martin, Ph.D., Gabriel H. T. Oh, B.Sc., Beverley A. Orser, M.D., F.R.C.P., Ph.D.

Anesthesiology. November 2009: 111(5):1025–1035

https://doi.org/10.1097/ALN.0b013e3181bbc961

Published: November 2009

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Articles

Three Editorials—Three Historical Allusions

Beverley A. Orser, M.D., Ph.D., F.R.C.P.C.

Anesthesiology. August 2009: 111(2):443

https://doi.org/10.1097/ALN.0b013e3181ac712d

Published: August 2009

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Articles

Multimodal Anesthesia and Systems Neuroscience: The New Frontier

Beverley A. Orser, M.D., Ph.D., F.R.C.P.C., Clifford B. Saper, M.D., Ph.D.

Anesthesiology. December 2008: 109(6):948–950

https://doi.org/10.1097/ALN.0b013e31818e47fb

Published: December 2008

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Articles

Medication Error: A Leading Cause of Anesthesia-related Morbidity and Mortality

Rachel Meyer, M.D., Beverley A. Orser, M.D., F.R.C.P.C., Ph.D., Robert Byrick, M.D., F.R.C.P.C.

Anesthesiology. December 2007: 107(6):1033

https://doi.org/10.1097/01.anes.0000290620.54964.96

Published: December 2007

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NARROW

Anesthesia and Developing Brains: Unanswered Questions and Proposed Paths Forward

2020 Severinghaus Lecture on Translational Science: Reply

Anesthesiology: Resetting Our Sights on Long-term Outcomes: The 2020 John W. Severinghaus Lecture on Translational Science

Perioperative Neurocognitive Disorder: State of the Preclinical Science

Musings from an Unlikely Clinician–Scientist: 2018 American Society of Anesthesiologists Excellence in Research Award

In Memoriam: Brian Kavanagh, 1962 to 2019

GABA A Receptor Theory of Perioperative Neurocognitive Disorders

Dexmedetomidine Prevents Excessive γ-Aminobutyric Acid Type A Receptor Function after Anesthesia

High Concentrations of Tranexamic Acid Inhibit Ionotropic Glutamate Receptors

Ketamine Increases the Function of γ-Aminobutyric Acid Type A Receptors in Hippocampal and Cortical Neurons

In Reply

Inflammation Increases Neuronal Sensitivity to General Anesthetics

Perioperative Medication Errors: Building Safer Systems

Isoflurane Regulates Atypical Type-A γ-Aminobutyric Acid Receptors in Alveolar Type II Epithelial Cells

Intraoperative Awareness: From Neurobiology to Clinical Practice

Short-term Memory Impairment after Isoflurane in Mice Is Prevented by the α5 γ-Aminobutyric Acid Type A Receptor Inverse Agonist L-655,708

Etomidate Targets α 5 γ-Aminobutyric Acid Subtype A Receptors to Regulate Synaptic Plasticity and Memory Blockade

Three Editorials—Three Historical Allusions

Multimodal Anesthesia and Systems Neuroscience: The New Frontier

Medication Error: A Leading Cause of Anesthesia-related Morbidity and Mortality

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