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Volume 82, Issue 6

June 1995

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In this Issue

Editorial
Clinical Science
Laboratory Investigations
Review Article
Case Reports
Correspondence
Reviews of Educational Material

Editorial

Aerosolized Prostacyclin: In Search of the Ideal Pulmonary Vasodilator

Randall C. Wetzel, MB, BS, FCCM, FAAP

Anesthesiology June 1995, Vol. 82, 1315–1317.. https://doi.org/10.1097/00000542-199506000-00001

View Articletitled, Aerosolized Prostacyclin: In Search of the Ideal Pulmonary Vasodilator

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Topics: epoprostenol , pulmonary vasodilators

Clinical Science

Inferences about Respiratory Muscle Use after Cardiac Surgery from Compartmental Volume and Pressure Measurements

F. Clergue, MD; W. A. Whitelaw, MD, PhD; J. C. Charles, MD; I. Gandjbakhch, MD; J. L. Pansard, MD; J.-P. Derenne, MD; P. Viars, MD

Anesthesiology June 1995, Vol. 82, 1318–1327.. https://doi.org/10.1097/00000542-199506000-00002

View Articletitled, Inferences about Respiratory Muscle Use after Cardiac Surgery from Compartmental Volume and Pressure Measurements

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Topics: abdomen , abdominal muscles , cardiac surgery procedures , expiration, function , inference

Pharmacokinetic Model Selection for Target Controlled Infusions of Propofol: Assessment of Three Parameter Sets

J. F Coetzee, BSc; MMed (Anes.) MBChB, DipDat, PhD; J. B. Glen, BVMS, PhD, DVA, Wium, C. A., MSc.(Pharm.); L. Boshoff, MBChB, MMed (Anes.), FFA (SA)

Anesthesiology June 1995, Vol. 82, 1328–1345.. https://doi.org/10.1097/00000542-199506000-00003

View Articletitled, Pharmacokinetic Model Selection for Target Controlled Infusions of Propofol: Assessment of Three Parameter Sets

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Topics: propofol , target-controlled infusion , infusion procedures

Clinical Effects and Maternal and Fetal Plasma Concentrations of Epidural Ropivacaine Versus Bupivacaine for Cesarean Section

Sanjay Datta, MD; FFARCS(Eng.); William Camann, MD; Angela Bader, MD; Laura VanderBurgh, RN

Anesthesiology June 1995, Vol. 82, 1346–1352.. https://doi.org/10.1097/00000542-199506000-00004

View Articletitled, Clinical Effects and Maternal and Fetal Plasma Concentrations of Epidural Ropivacaine Versus Bupivacaine for Cesarean Section

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Topics: bupivacaine , cesarean section , fetus , mothers , plasma drug concentration

Oral Clonidine Prolongs Lidocaine Spinal Anesthesia in Human Volunteers

Spencer MD Liu; Andrew A. Chiu, MD; Joseph M. Neal, MD; Randall L. Carpenter, MD; Bruce G. Bainton, MD; J. C. Gerancher, MD

Anesthesiology June 1995, Vol. 82, 1353–1359.. https://doi.org/10.1097/00000542-199506000-00005

View Articletitled, Oral Clonidine Prolongs Lidocaine Spinal Anesthesia in Human Volunteers

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Topics: clonidine , lidocaine , spinal anesthesia

Postpartum Changes in the Minimum Alveolar Concentration of Isoflurane

Matthew T. V. Chan, MB, BS; Tony Gin, MD., BSc, FRCA, FANZCA

Anesthesiology June 1995, Vol. 82, 1360–1363.. https://doi.org/10.1097/00000542-199506000-00006

View Articletitled, Postpartum Changes in the Minimum Alveolar Concentration of Isoflurane

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Topics: isoflurane , minimum alveolar concentration , postpartum period , monitored anesthesia care , progesterone

The Minimum Alveolar Concentration of Isoflurane in Patients Undergoing Bilateral Tubal Ligation in the Postpartum Period

Henry H. Zhou, MD, PhD; Patricia Norman, MD; Luiz G.R. DeLima, MD; Mahesh Mehta, MD; David Bass, PhD

Anesthesiology June 1995, Vol. 82, 1364–1368.. https://doi.org/10.1097/00000542-199506000-00007

View Articletitled, The Minimum Alveolar Concentration of Isoflurane in Patients Undergoing Bilateral Tubal Ligation in the Postpartum Period

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Topics: isoflurane , minimum alveolar concentration , postpartum period , tubal ligation

Clinical Sevoflurane Metabolism and Disposition: I. Sevoflurane and Metabolite Pharmacokinetics

Evan D. Kharasch, MD, PhD; Michael D. Karol, PhD; Carmine Lanni, PhD; Ronald Sawchuk, PhD

Anesthesiology June 1995, Vol. 82, 1369–1378.. https://doi.org/10.1097/00000542-199506000-00008

View Articletitled, Clinical Sevoflurane Metabolism and Disposition: I. Sevoflurane and Metabolite Pharmacokinetics

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Topics: fluorides , metabolism , metabolites , pharmacokinetics , plasma

Clinical Sevoflurane Metabolism and Disposition: II. The Role of Cytochrome P450 2E1 in Fluoride and Hexafluoroisopropanol Formation

Evan D. Kharasch, MD, PhD; Andrew S. Armstrong, MBBS, FANZCA; Kerry Gunn, MBChB, FANZCA; Alan Artru, MD; Kathy Cox, BS; Michael D. Karol, PhD

Anesthesiology June 1995, Vol. 82, 1379–1388.. https://doi.org/10.1097/00000542-199506000-00009

View Articletitled, Clinical Sevoflurane Metabolism and Disposition: II. The Role of Cytochrome P450 2E1 in Fluoride and Hexafluoroisopropanol Formation

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Topics: cytochrome p-450 cyp2e1 , fluorides , metabolism , sevoflurane , disulfiram

Effect of 7.2% Hypertonic Saline/6% Hetastarch on Left Ventricular Contractility in Anesthetized Humans

Axel W. Goertz, MD; Tobias Mehl, MD; Karl H. Lindner, MD; Michael G. Rockemann, MD; Uwe Schirmer, MD; Bernhard Schwilk, MD; Michael Georgieff, MD

Anesthesiology June 1995, Vol. 82, 1389–1395.. https://doi.org/10.1097/00000542-199506000-00010

View Articletitled, Effect of 7.2% Hypertonic Saline/6% Hetastarch on Left Ventricular Contractility in Anesthetized Humans

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Topics: hetastarch , left ventricle , saline solution, hypertonic , systole

Laboratory Investigations

Methohexital Impairs Osmoregulation: Studies in Conscious and Anesthetized Volume-expanded Dogs

Maieli Kasner, MD; Jochen Grosse; Martin Krebs, MD; Gabriele Kaczmarczyk, MD

Anesthesiology June 1995, Vol. 82, 1396–1405.. https://doi.org/10.1097/00000542-199506000-00011

View Articletitled, Methohexital Impairs Osmoregulation: Studies in Conscious and Anesthetized Volume-expanded Dogs

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Topics: dog, domestic , methohexital , water-electrolyte balance , sodium , vasopressins

Inhibition by Volatile Anesthetics of Endogenous Glutamate Release from Synaptosomes by a Presynaptic Mechanism

Michael Schlame, MD, PhD; Hugh C. Jr. Hemmings, MD, PhD

Anesthesiology June 1995, Vol. 82, 1406–1416.. https://doi.org/10.1097/00000542-199506000-00012

View Articletitled, Inhibition by Volatile Anesthetics of Endogenous Glutamate Release from Synaptosomes by a Presynaptic Mechanism

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Topics: glutamate , glutamates , halothane , synaptosomes , volatile anesthetics

Regulation of Norepinephrine Release by β²-Adrenergic Receptors during Halothane Anesthesia

Robert Deegan, MBB Ch, PhD, FFARCS(I); Huai Bing He, Pharm D; Yuri Krivoruk, MD; Alastair Wood, J. J. MB ChB, FRCP; Margaret Wood, MB ChB, FRCA

Anesthesiology June 1995, Vol. 82, 1417–1425.. https://doi.org/10.1097/00000542-199506000-00013

View Articletitled, Regulation of Norepinephrine Release by β2-Adrenergic Receptors during Halothane Anesthesia

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Topics: halothane , isoproterenol , norepinephrine , hindlimb , dog, domestic

Ketamine Has Stereospecific Effects in the Isolated Perfused Guinea Pig Heart

Bernhard M. Graf, MD; Martin N. Vicenzi, MD; Eike Martin, MD; Zeljko J. Bosnjak, PhD; David F. Stowe, MD, PhD

Anesthesiology June 1995, Vol. 82, 1426–1437.. https://doi.org/10.1097/00000542-199506000-00014

View Articletitled, Ketamine Has Stereospecific Effects in the Isolated Perfused Guinea Pig Heart

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Topics: heart , ketamine , guinea , catecholamines

A Subtype of α¹Adrenoceptor Mediates Depression of Conduction in Purkinje Fibers Exposed to Halothane

Lawrence A. Turner, MD; Sanja Vodanovic, MD; Raymond G. Hoffmann, PhD; John P. Kampine, MD, PhD; Zeljko J. Bosnjak, PhD

Anesthesiology June 1995, Vol. 82, 1438–1446.. https://doi.org/10.1097/00000542-199506000-00015

View Articletitled, A Subtype of α1Adrenoceptor Mediates Depression of Conduction in Purkinje Fibers Exposed to Halothane

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Topics: adrenergic receptor , depressive disorders , epinephrine , halothane , purkinje fibers

Anesthetics and Automaticity of Dominant and Latent Pacemakers in Chronically Instrumented Dogs: IV. Dysrhythmias after Sinoatrial Node Excision

Harvey J. Woehlck, MD; Martin N. Vicenzi, MD; Jurica Bajic, MD; Stephen M. Sokolyk, MD; Zeljko J. Bosnjak, PhD; John L. III Atlee, MD

Anesthesiology June 1995, Vol. 82, 1447–1455.. https://doi.org/10.1097/00000542-199506000-00016

View Articletitled, Anesthetics and Automaticity of Dominant and Latent Pacemakers in Chronically Instrumented Dogs: IV. Dysrhythmias after Sinoatrial Node Excision

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Topics: artificial cardiac pacemaker , automaticity , cardiac arrhythmia , dog, domestic , excision

Halothane Restores the Altered Force-Frequency Relationship in Failing Human Myocardium

Ulrich Schmidt, MD; Robert H. G. Schwinger, MD; Michael Bohm, MD

Anesthesiology June 1995, Vol. 82, 1456–1462.. https://doi.org/10.1097/00000542-199506000-00017

View Articletitled, Halothane Restores the Altered Force-Frequency Relationship in Failing Human Myocardium

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Topics: halothane , myocardium , heart , isoproterenol

The Local Anesthetic n-Butyl-p-Aminobenzoate Selectively Affects Inactivation of Fast Sodium Currents in Cultured Rat Sensory Neurons

R. J. Van den Berg, PhD; P. F. Van Soest, MSc; Z. Wang, MSc; R. J. E. Grouls, PharmD; H. H. M. Korsten, MD, PhD

Anesthesiology June 1995, Vol. 82, 1463–1473.. https://doi.org/10.1097/00000542-199506000-00018

View Articletitled, The Local Anesthetic n-Butyl-p-Aminobenzoate Selectively Affects Inactivation of Fast Sodium Currents in Cultured Rat Sensory Neurons

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Topics: anesthetics, local , sodium , 4-aminobenzoic acid , neurons, afferent , neurons

Review Article

Epidural Anesthesia and Analgesia: Their Role in Postoperative Outcome

Spencer Liu, MD; Randall L. Carpenter, MD; Joseph M. Neal, MD

Anesthesiology June 1995, Vol. 82, 1474–1506.. https://doi.org/10.1097/00000542-199506000-00019

View Articletitled, Epidural Anesthesia and Analgesia: Their Role in Postoperative Outcome

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Topics: analgesia (pain absence) , analgesia, epidural , anesthetics, local , epidural anesthesia , morbidity

Case Reports

Aerosolized Prostacyclin Versus Inhaled Nitric Oxide in Children with Severe Acute Respiratory Distress Syndrome

Dirk Pappert, MD; Thilo Busch; Herwig Gerlach, MD; Klaus Lewandowski, MD; Peter Radermacher, MD; Rolf Rossaint, MD

Anesthesiology June 1995, Vol. 82, 1507–1511.. https://doi.org/10.1097/00000542-199506000-00020

View Articletitled, Aerosolized Prostacyclin Versus Inhaled Nitric Oxide in Children with Severe Acute Respiratory Distress Syndrome

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Topics: child , epoprostenol , nitric oxide , respiratory distress syndrome, adult

Selective Pulmonary Vasodilation by Inhaled Prostacyclin in a Newborn with Congenital Heart Disease and Cardiopulmonary Bypass

B. Zwissler, MD; N. Rank, MD; U. Jaenicke, MD; B. Schurle, MD; M. Welte, MD, MD; B. Reichart, MD; H. Netz, MD; K. Messmer, MD; K. Peter, MD

Anesthesiology June 1995, Vol. 82, 1512–1516.. https://doi.org/10.1097/00000542-199506000-00021

View Articletitled, Selective Pulmonary Vasodilation by Inhaled Prostacyclin in a Newborn with Congenital Heart Disease and Cardiopulmonary Bypass

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Topics: cardiopulmonary bypass , congenital heart disease , epoprostenol , lung , newborn

Dissection of the Posterior Pharynx Resulting in Acute Airway Obstruction

Robert C. Baumann, MD; Drew A. MacGregor, MD

Anesthesiology June 1995, Vol. 82, 1516–1518.. https://doi.org/10.1097/00000542-199506000-00022

View Articletitled, Dissection of the Posterior Pharynx Resulting in Acute Airway Obstruction

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Topics: airway obstruction , pharynx , tissue dissection

Intraoperative Hyperkalemia as a Triggering Mechanism or Presenting Sign of Malignant Hyperthermia in Two Patients with Chronic Renal Failure

Juraj Sprung, MD, PhD; Glenn DeBoer, MD; Giorgio Zanettin, MD; Zeyd Ebrahim, MD; Joseph Ryckman, MD; Santosh Kalhan, MD; David Otto, MD

Anesthesiology June 1995, Vol. 82, 1518–1522.. https://doi.org/10.1097/00000542-199506000-00023

View Articletitled, Intraoperative Hyperkalemia as a Triggering Mechanism or Presenting Sign of Malignant Hyperthermia in Two Patients with Chronic Renal Failure

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Topics: hyperkalemia , intraoperative care , kidney failure, chronic , malignant hyperthermia due to anesthesia , myanmar

Epidural Abscess after Obstetric Epidural Analgesia

Stanley E. Borum, MD; Charles H. McLeskey, MD; John B. Williamson, MD; Frank S. Harris, MD; Alfred B. Knight, MD

Anesthesiology June 1995, Vol. 82, 1523–1526.. https://doi.org/10.1097/00000542-199506000-00024

View Articletitled, Epidural Abscess after Obstetric Epidural Analgesia

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Topics: analgesia, epidural , epidural abscess , obstetrics

Unintended Transthoracic Pulmonary Artery Cannulation: A Complication of Central Line Insertion

Craig W. Reid, MD, FRCPC; Peter J. Sheridan, MD, CM, FRCPC; Joelle F. Desparmet, MD; Vincent R. Adolph, MD

Anesthesiology June 1995, Vol. 82, 1526–1528.. https://doi.org/10.1097/00000542-199506000-00025

View Articletitled, Unintended Transthoracic Pulmonary Artery Cannulation: A Complication of Central Line Insertion

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Topics: catheterization , central venous catheterization , pulmonary artery , catheters

Intentional Occlusion of the Right Upper Lobe Bronchial Orifice to Tamponade Life-threatening Hemoptysis

Robert C. Morell, MD; Richard C. Prielipp, MD; Arthur S. Foreman, MD; Thomas J. Monaco, MD; Roger L. Royster, MD

Anesthesiology June 1995, Vol. 82, 1529–1531.. https://doi.org/10.1097/00000542-199506000-00026

View Articletitled, Intentional Occlusion of the Right Upper Lobe Bronchial Orifice to Tamponade Life-threatening Hemoptysis

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Topics: hemoptysis

Correspondence

Reply: Negative Pressure Ventilation during Tracheal Tube Exchange

Rieko Sumiyoshi, MD; Tetsuya Kai, MD

Anesthesiology June 1995, Vol. 82, 1533–1534.. https://doi.org/10.1097/00000542-199506000-00030

View Articletitled, Reply: Negative Pressure Ventilation during Tracheal Tube Exchange

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Reply: Postanesthesia Care Unit Costs

Franklin Dexter, MD, PhD

Anesthesiology June 1995, Vol. 82, 1534–1535.. https://doi.org/10.1097/00000542-199506000-00032

View Articletitled, Reply: Postanesthesia Care Unit Costs

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Reply: Nasal Midazolam in Children

Peter J. Davis, MD; Julie A. Tome, MD; Francis X. Jr. McGowan, MD; Ira Todd Cohen, MD

Anesthesiology June 1995, Vol. 82, 1535–1536.. https://doi.org/10.1097/00000542-199506000-00034

View Articletitled, Reply: Nasal Midazolam in Children

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Intraoperative Transcranial Doppler Monitoring

Arthur M. Lam, MD

Anesthesiology June 1995, Vol. 82, 1536–1537.. https://doi.org/10.1097/00000542-199506000-00035

View Articletitled, Intraoperative Transcranial Doppler Monitoring

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Peri- or Postoperative Ulnar Neuropathy?

Paul Martin Kempen, MD, PhD

Anesthesiology June 1995, Vol. 82, 1538–1539.. https://doi.org/10.1097/00000542-199506000-00037

View Articletitled, Peri- or Postoperative Ulnar Neuropathy?

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Reply: Peri- or Postoperative Ulnar Neuropathy

Mark A. Warner, MD; Mary E. Warner, MD; John T. Martin, MD

Anesthesiology June 1995, Vol. 82, 1539–1540.. https://doi.org/10.1097/00000542-199506000-00038

View Articletitled, Reply: Peri- or Postoperative Ulnar Neuropathy

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Should Acidosis during Liver Transplantation Be Treated?

David L. Bogdonoff, MD; Burkhard F. Spiekermann, MD

Anesthesiology June 1995, Vol. 82, 1540–1541.. https://doi.org/10.1097/00000542-199506000-00039

View Articletitled, Should Acidosis during Liver Transplantation Be Treated?

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Reply: Should the Government Continue to Fund Basic Biomedical Research?

J. G. Collins, PhD

Anesthesiology June 1995, Vol. 82, 1542–1543.. https://doi.org/10.1097/00000542-199506000-00042

View Articletitled, Reply: Should the Government Continue to Fund Basic Biomedical Research?

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Reviews of Educational Material

Obstetric Anesthesia: Principles and Practice

Sivam Ramanathan, MD

Anesthesiology June 1995, Vol. 82, 1545–1546.. https://doi.org/10.1097/00000542-199506000-00047

View Articletitled, Obstetric Anesthesia: Principles and Practice

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Topics: anesthesia, obstetrical

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