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Volume 131, Issue 5

November 2019

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In this Issue

Table of Contents
Editorial Board
This Month in Anesthesiology
Science, Medicine, and the Anesthesiologist
Infographics in Anesthesiology
Anesthesiology CME Program
Editorial
Perioperative Medicine: Clinical Science
Perioperative Medicine: Basic Science
Critical Care Medicine: Basic Science
Pain Medicine: Basic Science
Education: Images in Anesthesiology
Education: Clinical Focus Review
Education: Review Article
Education: Mind to Mind
Correspondence
Anesthesiology Reflections from the Wood Library-Museum

Anesthesiology

Anesthesiology November 2019, Vol. 131, A5–A9. https://doi.org/10.1097/ALN.0000000000003031

View Articletitled, Anesthesiology

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Editorial Board

Anesthesiology

Anesthesiology November 2019, Vol. 131, A11–A12. https://doi.org/10.1097/ALN.0000000000003006

View Articletitled, Anesthesiology

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This Month in Anesthesiology

Anesthesiology November 2019, Vol. 131, A1–A2. https://doi.org/10.1097/ALN.0000000000003012

View Articletitled, This Month in Anesthesiology

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Science, Medicine, and the Anesthesiologist

Anesthesiology November 2019, Vol. 131, A15–A18. https://doi.org/10.1097/ALN.0000000000003013

View Articletitled, Science, Medicine, and the Anesthesiologist

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Infographics in Anesthesiology

Safe Sedation Re-examined: Comparing the Respiratory Effects of Dexmedetomidine and Propofol

Jonathan P. Wanderer; James P. Rathmell

Anesthesiology November 2019, Vol. 131, A19. https://doi.org/10.1097/ALN.0000000000003008

View Articletitled, Safe Sedation Re-examined: Comparing the Respiratory Effects of Dexmedetomidine and Propofol

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Topics: dexmedetomidine , propofol , sedation procedure

Anesthesiology CME Program

Instructions for Obtaining Anesthesiology Continuing Medical Education (CME) Credit
CME Article

Anesthesiology November 2019, Vol. 131, A13. https://doi.org/10.1097/ALN.0000000000003007

View Articletitled, Instructions for Obtaining Anesthesiology Continuing Medical Education (CME) Credit

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Editorial

Reporting Laboratory and Animal Research in Anesthesiology: The Importance of Sex as a Biologic Variable

Laszlo Vutskits, M.D., Ph.D.; J. David Clark, M.D., Ph.D.; Evan D. Kharasch, M.D., Ph.D.

Anesthesiology November 2019, Vol. 131, 949–952. https://doi.org/10.1097/ALN.0000000000002945

View Articletitled, Reporting Laboratory and Animal Research in Anesthesiology: The Importance of Sex as a Biologic Variable

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Topics: animals, laboratory , clinical research , data analysis , gender , guidelines

Dexmedetomidine and the Upper Airway: Not as Simple as We Hoped

Denham S. Ward, M.D., Ph.D.; Suzanne B. Karan, M.D.

Anesthesiology November 2019, Vol. 131, 953–954. https://doi.org/10.1097/ALN.0000000000002965

View Articletitled, Dexmedetomidine and the Upper Airway: Not as Simple as We Hoped

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Topics: dexmedetomidine , upper respiratory tract

Be Wary of Genes Governing Awareness

Philip G. Morgan, M.D.; Max B. Kelz, M.D., Ph.D.

Anesthesiology November 2019, Vol. 131, 955–956. https://doi.org/10.1097/ALN.0000000000002886

View Articletitled, Be Wary of Genes Governing Awareness

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Topics: genes

Mission Impossible or Mission Futile?: Estimating Penetrance for Malignant Hyperthermia

Marie-Anne Shaw, Ph.D.; Philip M. Hopkins, M.B.B.S., M.D., F.R.C.A.

Anesthesiology November 2019, Vol. 131, 957–959. https://doi.org/10.1097/ALN.0000000000002884

View Articletitled, Mission Impossible or Mission Futile?: Estimating Penetrance for Malignant Hyperthermia

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Topics: malignant hyperthermia due to anesthesia , penetrance, genetic

Preoperative Assessment of Functional Capacity: Looking beyond the Ability to Climb Stairs

Duminda N. Wijeysundera, M.D., Ph.D.

Anesthesiology November 2019, Vol. 131, 960–961. https://doi.org/10.1097/ALN.0000000000002958

View Articletitled, Preoperative Assessment of Functional Capacity: Looking beyond the Ability to Climb Stairs

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Topics: ascending stairs , functional capacity , preoperative medical evaluation

Perioperative Medicine: Clinical Science

Upper Airway Collapsibility during Dexmedetomidine and Propofol Sedation in Healthy Volunteers: A Nonblinded Randomized Crossover Study
This article has a Visual Abstract This article has an Audio Podcast

Åse Lodenius, M.D., Ph.D., D.E.S.A.; Kathleen J. Maddison, Ph.D.; Brad K. Lawther, M.D.; Mika Scheinin, M.D., Ph.D.; Lars I. Eriksson, M.D., Ph.D., F.R.C.A.; Peter R. Eastwood, Ph.D.; David R. Hillman, M.B.B.S.; Malin Jonsson Fagerlund, M.D., Ph.D., D.E.S.A.; Jennifer H. Walsh, M.Sc., Ph.D.

Anesthesiology November 2019, Vol. 131, 962–973. https://doi.org/10.1097/ALN.0000000000002883

View Articletitled, Upper Airway Collapsibility during Dexmedetomidine and Propofol Sedation in Healthy Volunteers: A Nonblinded Randomized Crossover Study

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Topics: dexmedetomidine , propofol , sedation procedure , upper respiratory tract , pharynx

Genetic Analysis of Patients Who Experienced Awareness with Recall while under General Anesthesia
This article has a Visual Abstract

Jamie W. Sleigh, M.D.; Kate Leslie, M.D.; Andrew J. Davidson, M.D.; David J. Amor, Ph.D.; Peter Diakumis, M.Bioinf.; Vesna Lukic, M.Sci.; Paul J. Lockhart, Ph.D.; Melanie Bahlo, Ph.D.

Anesthesiology November 2019, Vol. 131, 974–982. https://doi.org/10.1097/ALN.0000000000002877

View Articletitled, Genetic Analysis of Patients Who Experienced Awareness with Recall while under General Anesthesia

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Topics: anesthesia, general , genetic analysis , mental recall , whole exome sequencing , genes

An Assessment of Penetrance and Clinical Expression of Malignant Hyperthermia in Individuals Carrying Diagnostic Ryanodine Receptor 1 Gene Mutations
This article has a Visual Abstract

Carlos A. Ibarra Moreno, M.D., Ph.D.; Sally Hu, M.D.; Natalia Kraeva, Ph.D.; Frank Schuster, M.D.; Stephan Johannsen, M.D.; Henrik Rueffert, M.D.; Werner Klingler, M.D., Ph.D.; Luc Heytens, M.D., Ph.D.; Sheila Riazi, M.Sc., M.D.

Anesthesiology November 2019, Vol. 131, 983–991. https://doi.org/10.1097/ALN.0000000000002813

View Articletitled, An Assessment of Penetrance and Clinical Expression of Malignant Hyperthermia in Individuals Carrying Diagnostic Ryanodine Receptor 1 Gene Mutations

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Topics: malignant hyperthermia due to anesthesia , mutation , penetrance, genetic , precipitating factors , proband

Accuracy of Physical Function Questions to Predict Moderate-Vigorous Physical Activity as Measured by Hip Accelerometry

Daniel S. Rubin, M.D., M.S.; Megan Huisingh-Scheetz, M.D.; Anthony Hung, B.S.; R. Parker Ward, M.D.; Peter Nagele, M.D., M.Sc.; Ross Arena, Ph.D., P.T.; Donald Hedeker, Ph.D.

Anesthesiology November 2019, Vol. 131, 992–1003. https://doi.org/10.1097/ALN.0000000000002911

View Articletitled, Accuracy of Physical Function Questions to Predict Moderate-Vigorous Physical Activity as Measured by Hip Accelerometry

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Topics: hip joint , hip region , national health and nutrition examination survey , physical activity , physical function

Pharmacodynamic Interaction of Remifentanil and Dexmedetomidine on Depth of Sedation and Tolerance of Laryngoscopy

Maud A. S. Weerink, M.D.; Clemens R. M. Barends, M.D.; Ernesto R. R. Muskiet, M.D.; Koen M. E. M. Reyntjens, M.D.; Froukje H. Knotnerus, R.N.; Martine Oostra, R.N.; Jan F. P. van Bocxlaer, Pharm.D., Ph.D.; Michel M. R. F. Struys, M.D., Ph.D., F.R.C.A.; Pieter J. Colin, Pharm.D., Ph.D.

Anesthesiology November 2019, Vol. 131, 1004–1017. https://doi.org/10.1097/ALN.0000000000002882

View Articletitled, Pharmacodynamic Interaction of Remifentanil and Dexmedetomidine on Depth of Sedation and Tolerance of Laryngoscopy

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Topics: dexmedetomidine , laryngoscopy , pharmacodynamic interaction , remifentanil , trapezius muscle

Acoustic Shadowing Facilitates Ultrasound-guided Radial Artery Cannulation in Young Children
This article has a Visual Abstract

ZheFeng Quan, M.D.; Liang Zhang, M.D.; Chen Zhou, M.D.; Ping Chi, M.D.; HaiLi He, M.M.; Ying Li, M.M.

Anesthesiology November 2019, Vol. 131, 1018–1024. https://doi.org/10.1097/ALN.0000000000002948

View Articletitled, Acoustic Shadowing Facilitates Ultrasound-guided Radial Artery Cannulation in Young Children

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Topics: acoustic shadowing , child , puncture procedure , puncture wound , radial artery

A Population-based Comparative Effectiveness Study of Peripheral Nerve Blocks for Hip Fracture Surgery

Gavin M. Hamilton, M.D., M.Sc.; Manoj M. Lalu, M.D., Ph.D., F.R.C.P.C.; Reva Ramlogan, M.D., F.R.C.P.C.; Gregory L. Bryson, M.D., M.Sc., F.R.C.P.C.; Faraj W. Abdallah, M.D., M.Sc.; Colin J. L. McCartney, M.B.Ch.B., Ph.D., F.R.C.A., F.C.A.R.C.S.I.; Daniel I. McIsaac, M.D., M.P.H., F.R.C.P.C.

Anesthesiology November 2019, Vol. 131, 1025–1035. https://doi.org/10.1097/ALN.0000000000002947

View Articletitled, A Population-based Comparative Effectiveness Study of Peripheral Nerve Blocks for Hip Fracture Surgery

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Topics: hip fracture repair , peripheral block anesthesia , length of stay , comparative effectiveness research

Effect of a Cognitive Aid on Reducing Sugammadex Use and Associated Costs: A Time Series Analysis

Dan M. Drzymalski, M.D.; Roman Schumann, M.D.; Frank J. Massaro, Pharm.D.; Agnieszka Trzcinka, M.D.; Ruben J. Azocar, M.D.

Anesthesiology November 2019, Vol. 131, 1036–1045. https://doi.org/10.1097/ALN.0000000000002946

View Articletitled, Effect of a Cognitive Aid on Reducing Sugammadex Use and Associated Costs: A Time Series Analysis

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Topics: sugammadex , anesthetics, general , interrupted time series analysis

Intraoperative Mechanical Ventilation and Postoperative Pulmonary Complications after Cardiac Surgery

Michael R. Mathis, M.D.; Neal M. Duggal, M.D.; Donald S. Likosky, Ph.D.; Jonathan W. Haft, M.D.; Nicholas J. Douville, M.D., Ph.D.; Michelle T. Vaughn, M.P.H.; Michael D. Maile, M.D., M.S.; Randal S. Blank, M.D., Ph.D.; Douglas A. Colquhoun, M.B., Ch.B., M.Sc., M.P.H.; Raymond J. Strobel, M.D., M.S.; Allison M. Janda, M.D.; Min Zhang, Ph.D.; Sachin Kheterpal, M.D., M.B.A.; Milo C. Engoren, M.D.

Anesthesiology November 2019, Vol. 131, 1046–1062. https://doi.org/10.1097/ALN.0000000000002909

View Articletitled, Intraoperative Mechanical Ventilation and Postoperative Pulmonary Complications after Cardiac Surgery

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Topics: cardiac surgery procedures , intraoperative care , mechanical ventilation , protective ventilation , pulmonary complications

Perioperative Medicine: Basic Science

Nitrous Oxide Impairs Axon Regeneration after Nervous System Injury in Male Rats
This article has a Video Abstract

Krista J. Stewart, M.D.; Bermans J. Iskandar, M.D.; Brenton M. Meier, M.D.; Elias B. Rizk, M.D.; Nithya Hariharan, M.D.; Joyce Koueik, M.D., M.S.; Adin-Christian Andrei, Ph.D.; Kirk J. Hogan, M.D., J.D.

Anesthesiology November 2019, Vol. 131, 1063–1076. https://doi.org/10.1097/ALN.0000000000002906

View Articletitled, Nitrous Oxide Impairs Axon Regeneration after Nervous System Injury in Male Rats

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Topics: axon , nitrous oxide , rats , ganglia, spinal , nervous system trauma

Early Postnatal Exposure to Isoflurane Disrupts Oligodendrocyte Development and Myelin Formation in the Mouse Hippocampus

Qun Li, Ph.D.; Reilley P. Mathena, B.S.; Jing Xu, M.D.; O’Rukevwe N. Eregha, B.A.; Jieqiong Wen, B.S.; Cyrus D. Mintz, M.D., Ph.D.

Anesthesiology November 2019, Vol. 131, 1077–1091. https://doi.org/10.1097/ALN.0000000000002904

View Articletitled, Early Postnatal Exposure to Isoflurane Disrupts Oligodendrocyte Development and Myelin Formation in the Mouse Hippocampus

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Topics: hippocampus , isoflurane , mice , oligodendroglia , myelination

Intergenerational Effects of Sevoflurane in Young Adult Rats

Ling-Sha Ju, M.D.; Jiao-Jiao Yang, M.D.; Ning Xu, M.D.; Jia Li, M.D.; Timothy E. Morey, M.D.; Nikolaus Gravenstein, M.D.; Christoph N. Seubert, M.D.; Barry Setlow, Ph.D.; Anatoly E. Martynyuk, Ph.D.

Anesthesiology November 2019, Vol. 131, 1092–1109. https://doi.org/10.1097/ALN.0000000000002920

View Articletitled, Intergenerational Effects of Sevoflurane in Young Adult Rats

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Topics: rats , sevoflurane , young adult , adult , offspring

Critical Care Medicine: Basic Science

Effect of Polyethylene-glycolated Carboxyhemoglobin on Renal Microcirculation in a Rat Model of Hemorrhagic Shock

Philippe Guerci, M.D.; Bulent Ergin, Ph.D.; Aysegul Kapucu, Ph.D.; Matthias P. Hilty, M.D.; Ronald Jubin, Ph.D.; Jan Bakker, M.D., Ph.D.; Can Ince, Ph.D.

Anesthesiology November 2019, Vol. 131, 1110–1124. https://doi.org/10.1097/ALN.0000000000002932

View Articletitled, Effect of Polyethylene-glycolated Carboxyhemoglobin on Renal Microcirculation in a Rat Model of Hemorrhagic Shock

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Topics: carboxyhemoglobin , kidney , polyethylene , shock, hemorrhagic , hetastarch

Pain Medicine: Basic Science

Vascular Endothelial Growth Factor A Signaling Promotes Spinal Central Sensitization and Pain-related Behaviors in Female Rats with Bone Cancer

Xue-Ming Hu, M.D., Ph.D.; Wei Yang, M.D., Ph.D.; Li-Xia Du, Ph.D.; Wen-Qiang Cui, M.D., Ph.D.; Wen-Li Mi, M.D., Ph.D.; Qi-Liang Mao-Ying, Ph.D.; Yu-Xia Chu, Ph.D.; Yan-Qing Wang, Ph.D.

Anesthesiology November 2019, Vol. 131, 1125–1147. https://doi.org/10.1097/ALN.0000000000002916

View Articletitled, Vascular Endothelial Growth Factor A Signaling Promotes Spinal Central Sensitization and Pain-related Behaviors in Female Rats with Bone Cancer

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Topics: malignant bone neoplasms , neoplasms , pain , rats , vascular endothelial growth factor a

Education: Images in Anesthesiology

The Lung Point: Early Identification of Pneumothorax on Point of Care Ultrasound

Babar Fiza, M.D.; Vanessa Moll, M.D., Ph.D., D.E.S.A.; Natalie Ferrero, M.D.

Anesthesiology November 2019, Vol. 131, 1148. https://doi.org/10.1097/ALN.0000000000002843

View Articletitled, The Lung Point: Early Identification of Pneumothorax on Point of Care Ultrasound

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Topics: early diagnosis , lung , pneumothorax , point-of-care ultrasonography

Resection of an Adrenocortical Carcinoma Invading the Inferior Vena Cava Extending into the Right Ventricle

Miguel R. Abalo, M.D.; John Carey, M.D.; Oscar Aljure, M.D.; Yiliam F. Rodriguez Blanco, M.D.

Anesthesiology November 2019, Vol. 131, 1149–1150. https://doi.org/10.1097/ALN.0000000000002866

View Articletitled, Resection of an Adrenocortical Carcinoma Invading the Inferior Vena Cava Extending into the Right Ventricle

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Topics: adrenocortical carcinoma , inferior vena cava , right ventricle

Pitfalls of a Shared Neuraxial Space: Wandering Epidural Catheter

Rani A. Sunder, M.D.; Eric J. Monroe, M.D.; Sean H. Flack, M.B., Ch.B., F.C.A.

Anesthesiology November 2019, Vol. 131, 1151. https://doi.org/10.1097/ALN.0000000000002900

View Articletitled, Pitfalls of a Shared Neuraxial Space: Wandering Epidural Catheter

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Topics: epidural catheters , physical wandering

Split Larynx

Ashish Bindra, M.D., D.M.; Sharmishtha Pathak, M.D.; Kapil Sikka, M.S.

Anesthesiology November 2019, Vol. 131, 1152. https://doi.org/10.1097/ALN.0000000000002867

View Articletitled, Split Larynx

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Topics: larynx

Education: Clinical Focus Review

Four-factor Prothrombin Complex Concentrate for the Management of Patients Receiving Direct Oral Activated Factor X Inhibitors
CME Article

Oliver Grottke, M.D., Ph.D.; Sam Schulman, M.D., Ph.D.

Anesthesiology November 2019, Vol. 131, 1153–1165. https://doi.org/10.1097/ALN.0000000000002910

View Articletitled, Four-factor Prothrombin Complex Concentrate for the Management of Patients Receiving Direct Oral Activated Factor X Inhibitors

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Topics: factor ix concentrates , factor xa inhibitors , hemorrhage , direct oral anticoagulants , anticoagulation

Education: Review Article

Transversus Abdominis Plane Block: A Narrative Review

De Q. Tran, M.D., F.R.C.P.C.; Daniela Bravo, M.D.; Prangmalee Leurcharusmee, M.D.; Joseph M. Neal, M.D.

Anesthesiology November 2019, Vol. 131, 1166–1190. https://doi.org/10.1097/ALN.0000000000002842

View Articletitled, Transversus Abdominis Plane Block: A Narrative Review

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Topics: transversus abdominis plane block , anesthesia, local , anesthetics, local

Education: Mind to Mind

My Brother’s Ghost
Part of the Letheon Writing Competition

Regine Cabato, A.B.

Anesthesiology November 2019, Vol. 131, 1191. https://doi.org/10.1097/ALN.0000000000002951

View Articletitled, My Brother’s Ghost

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Topics: child , father , death , diagnostic radiologic examination , file (record)

Bacchus Listed for a Liver Transplant

Douglas L. Hester, M.D., M.F.A.

Anesthesiology November 2019, Vol. 131, 1192. https://doi.org/10.1097/ALN.0000000000002844

View Articletitled, Bacchus Listed for a Liver Transplant

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Topics: liver transplantation

Correspondence

Driving Pressure–guided Ventilation: Comment

Michael A. Fierro, M.D.

Anesthesiology November 2019, Vol. 131, 1193. https://doi.org/10.1097/ALN.0000000000002954

View Articletitled, Driving Pressure–guided Ventilation: Comment

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Driving Pressure–guided Ventilation: Comment

David Amar, M.D.

Anesthesiology November 2019, Vol. 131, 1193–1194. https://doi.org/10.1097/ALN.0000000000002953

View Articletitled, Driving Pressure–guided Ventilation: Comment

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Driving Pressure–guided Ventilation: Reply

MiHye Park, M.D.; Hyun Joo Ahn, M.D.

Anesthesiology November 2019, Vol. 131, 1194–1195. https://doi.org/10.1097/ALN.0000000000002952

View Articletitled, Driving Pressure–guided Ventilation: Reply

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Extracorporeal Membrane Oxygenation 1-yr Outcome: Comment

Thomas Phillips, D.O.; Ryan J. Fink, M.D.

Anesthesiology November 2019, Vol. 131, 1195–1196. https://doi.org/10.1097/ALN.0000000000002971

View Articletitled, Extracorporeal Membrane Oxygenation 1-yr Outcome: Comment

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Extracorporeal Membrane Oxygenation 1-yr Outcome: Reply

Giacomo Grasselli, M.D.; Vittorio Scaravilli, M.D.; Davide Chiumello, M.D.

Anesthesiology November 2019, Vol. 131, 1196–1197. https://doi.org/10.1097/ALN.0000000000002970

View Articletitled, Extracorporeal Membrane Oxygenation 1-yr Outcome: Reply

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Anesthesiology Reflections from the Wood Library-Museum

From Jerking Teeth to Clerking Harvard: Dr. Hiram Whitney and His Patients' Ethereal Requests

Anesthesiology November 2019, Vol. 131, 1045. https://doi.org/10.1097/ALN.0000000000003009

View Articletitled, From Jerking Teeth to Clerking Harvard: Dr. Hiram Whitney and His Patients' Ethereal Requests

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Dr. Rudolph Matas: Surgeon, Author, and an American Pioneer of Spinal Anesthesia

Anesthesiology November 2019, Vol. 131, 1062. https://doi.org/10.1097/ALN.0000000000003010

View Articletitled, Dr. Rudolph Matas: Surgeon, Author, and an American Pioneer of Spinal Anesthesia

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From Fixing Photos to Fixing Cyanide Poisoning: Herschel's “Hypo” or Sodium Thiosulfate

Anesthesiology November 2019, Vol. 131, 1124. https://doi.org/10.1097/ALN.0000000000003011

View Articletitled, From Fixing Photos to Fixing Cyanide Poisoning: Herschel's “Hypo” or Sodium Thiosulfate

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Issues

Cover Image

Table of Contents

Editorial Board

This Month in Anesthesiology

Science, Medicine, and the Anesthesiologist

Infographics in Anesthesiology

Anesthesiology CME Program

Instructions for Obtaining Anesthesiology Continuing Medical Education (CME) Credit CME Article

Editorial

Perioperative Medicine: Clinical Science

Upper Airway Collapsibility during Dexmedetomidine and Propofol Sedation in Healthy Volunteers: A Nonblinded Randomized Crossover Study This article has a Visual Abstract This article has an Audio Podcast

Genetic Analysis of Patients Who Experienced Awareness with Recall while under General Anesthesia This article has a Visual Abstract

An Assessment of Penetrance and Clinical Expression of Malignant Hyperthermia in Individuals Carrying Diagnostic Ryanodine Receptor 1 Gene Mutations This article has a Visual Abstract

Acoustic Shadowing Facilitates Ultrasound-guided Radial Artery Cannulation in Young Children This article has a Visual Abstract

Perioperative Medicine: Basic Science

Nitrous Oxide Impairs Axon Regeneration after Nervous System Injury in Male Rats This article has a Video Abstract

Critical Care Medicine: Basic Science

Pain Medicine: Basic Science

Education: Images in Anesthesiology

Education: Clinical Focus Review

Four-factor Prothrombin Complex Concentrate for the Management of Patients Receiving Direct Oral Activated Factor X Inhibitors CME Article

Education: Review Article

Education: Mind to Mind

My Brother’s Ghost Part of the Letheon Writing Competition

Correspondence

Anesthesiology Reflections from the Wood Library-Museum

Email alerts

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Social Media

This Feature Is Available To Subscribers Only

Instructions for Obtaining Anesthesiology Continuing Medical Education (CME) Credit
CME Article

Upper Airway Collapsibility during Dexmedetomidine and Propofol Sedation in Healthy Volunteers: A Nonblinded Randomized Crossover Study
This article has a Visual Abstract This article has an Audio Podcast

Genetic Analysis of Patients Who Experienced Awareness with Recall while under General Anesthesia
This article has a Visual Abstract

An Assessment of Penetrance and Clinical Expression of Malignant Hyperthermia in Individuals Carrying Diagnostic Ryanodine Receptor 1 Gene Mutations
This article has a Visual Abstract

Acoustic Shadowing Facilitates Ultrasound-guided Radial Artery Cannulation in Young Children
This article has a Visual Abstract

Nitrous Oxide Impairs Axon Regeneration after Nervous System Injury in Male Rats
This article has a Video Abstract

Four-factor Prothrombin Complex Concentrate for the Management of Patients Receiving Direct Oral Activated Factor X Inhibitors
CME Article

My Brother’s Ghost
Part of the Letheon Writing Competition