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Volume 130, Issue 5

May 2019

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In this Issue

Table of Contents
Editorial Board
This Month in Anesthesiology
Science, Medicine, and the Anesthesiologist
Infographics in Anesthesiology
Anesthesiology CME Program
Editorial
Special Articles
Perioperative Medicine: Clinical Science
Critical Care Medicine: Basic Science
Critical Care Medicine: Clinical Science
Pain Medicine: Basic Science
Education: Images in Anesthesiology
Education: Clinical Focus Review
Education: Review Article
Education: Mind to Mind
Correspondence
Anesthesiology Reflections from the Wood Library-Museum

Anesthesiology

Anesthesiology May 2019, Vol. 130, A7–A10. https://doi.org/10.1097/ALN.0000000000002769

View Articletitled, Anesthesiology

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Editorial Board

Anesthesiology

Anesthesiology May 2019, Vol. 130, A11–A12. https://doi.org/10.1097/ALN.0000000000002747

View Articletitled, Anesthesiology

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This Month in Anesthesiology

Anesthesiology May 2019, Vol. 130, A5–A6. https://doi.org/10.1097/ALN.0000000000002746

View Articletitled, This Month in Anesthesiology

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Science, Medicine, and the Anesthesiologist

Anesthesiology May 2019, Vol. 130, A15–A18. https://doi.org/10.1097/ALN.0000000000002750

View Articletitled, Science, Medicine, and the Anesthesiologist

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Infographics in Anesthesiology

Monitoring Cardiac Output: A Big Problem for Little Patients

Jonathan P. Wanderer; James P. Rathmell

Anesthesiology May 2019, Vol. 130, A19. https://doi.org/10.1097/ALN.0000000000002749

View Articletitled, Monitoring Cardiac Output: A Big Problem for Little Patients

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Topics: cardiac output

Anesthesiology CME Program

Instructions for Obtaining Anesthesiology Continuing Medical Education (CME) Credit

Anesthesiology May 2019, Vol. 130, A13. https://doi.org/10.1097/ALN.0000000000002748

View Articletitled, Instructions for Obtaining Anesthesiology Continuing Medical Education (CME) Credit

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Editorial

Babies and Children at Last: Pediatric Cardiac Output Monitoring in the Twenty-first Century

Christine T. Trieu, M.D.; Tiffany M. Williams, M.D., Ph.D.; Maxime Cannesson, M.D., Ph.D.; Jure Marijic, M.D.

Anesthesiology May 2019, Vol. 130, 671–673. https://doi.org/10.1097/ALN.0000000000002673

View Articletitled, Babies and Children at Last: Pediatric Cardiac Output Monitoring in the Twenty-first Century

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Topics: child , infant , measurement of cardiac output , pediatrics

Can the Brain Predict Fluid Responsiveness?

Elliot Long, B.M.B.S., F.R.A.C.P.; Paul E. Marik, M.D., F.C.C.P., F.C.C.M.

Anesthesiology May 2019, Vol. 130, 674–676. https://doi.org/10.1097/ALN.0000000000002587

View Articletitled, Can the Brain Predict Fluid Responsiveness?

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Topics: brain

Perioperative Fluid Management: Turning Art to Science

Harriet W. Hopf, M.D., F.A.S.A.; Candice Morrissey, M.D., M.S.P.H.

Anesthesiology May 2019, Vol. 130, 677–679. https://doi.org/10.1097/ALN.0000000000002663

View Articletitled, Perioperative Fluid Management: Turning Art to Science

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Topics: fluid management , colloids

Mechanical Ventilation in Acute Respiratory Distress Syndrome: Time Heals All Wounds, or Does It?

Lorenzo Del Sorbo, M.D.; Rolf Hubmayr, M.D.; Arthur S. Slutsky, C.M., M.D., F.R.S.C.

Anesthesiology May 2019, Vol. 130, 680–682. https://doi.org/10.1097/ALN.0000000000002671

View Articletitled, Mechanical Ventilation in Acute Respiratory Distress Syndrome: Time Heals All Wounds, or Does It?

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Topics: mechanical ventilation , respiratory distress syndrome, adult , lung

Is a Part Better than the Whole for Cell-based Therapy for Acute Respiratory Distress Syndrome?

Jae W. Lee, M.D.; Michael A. Matthay, M.D.

Anesthesiology May 2019, Vol. 130, 683–685. https://doi.org/10.1097/ALN.0000000000002653

View Articletitled, Is a Part Better than the Whole for Cell-based Therapy for Acute Respiratory Distress Syndrome?

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Topics: respiratory distress syndrome, adult

Special Articles

An Anesthesiologist’s Perspective on the History of Basic Airway Management: The “Modern” Era, 1960 to Present

Adrian A. Matioc, M.D.

Anesthesiology May 2019, Vol. 130, 686–711. https://doi.org/10.1097/ALN.0000000000002646

View Articletitled, An Anesthesiologist’s Perspective on the History of Basic Airway Management: The “Modern” Era, 1960 to Present

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Topics: airway device , airway maintenance , environmental air flow , masks , respiration

Perioperative Medicine: Clinical Science

Extracorporeal Arteriovenous Ultrasound Measurement of Cardiac Output in Small Children

Theodor S. Sigurdsson, M.D.; Anders Aronsson, M.D.; Lars Lindberg, M.D., Ph.D.

Anesthesiology May 2019, Vol. 130, 712–718. https://doi.org/10.1097/ALN.0000000000002582

View Articletitled, Extracorporeal Arteriovenous Ultrasound Measurement of Cardiac Output in Small Children

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Topics: child , fluid flow , measurement of cardiac output , saline solutions , ultrasonography

Respiratory Variation of Internal Carotid Artery Blood Flow Peak Velocity Measured by Transfontanelle Ultrasound to Predict Fluid Responsiveness in Infants: A Prospective Observational Study

Eun-Hee Kim, M.D.; Ji-Hyun Lee, M.D.; In-Kyung Song, M.D.; Hee-Soo Kim, M.D., Ph.D.; Young-Eun Jang, M.D.; Jin-Tae Kim, M.D., Ph.D.

Anesthesiology May 2019, Vol. 130, 719–727. https://doi.org/10.1097/ALN.0000000000002526

View Articletitled, Respiratory Variation of Internal Carotid Artery Blood Flow Peak Velocity Measured by Transfontanelle Ultrasound to Predict Fluid Responsiveness in Infants: A Prospective Observational Study

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Topics: infant , internal carotid artery , peak arterial velocity , ultrasonography , vascular flow

Effect of Intraoperative Goal-directed Balanced Crystalloid versus Colloid Administration on Major Postoperative Morbidity: A Randomized Trial

Barbara Kabon, M.D.; Daniel I. Sessler, M.D.; Andrea Kurz, M.D.; on behalf of the Crystalloid–Colloid Study Team

Anesthesiology May 2019, Vol. 130, 728–744. https://doi.org/10.1097/ALN.0000000000002601

View Articletitled, Effect of Intraoperative Goal-directed Balanced Crystalloid versus Colloid Administration on Major Postoperative Morbidity: A Randomized Trial

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Topics: colloids , crystalloid solutions , intraoperative care , morbidity , creatinine tests, serum

Nociception-guided versus Standard Care during Remifentanil–Propofol Anesthesia: A Randomized Controlled Trial

Fleur S. Meijer, M.D.; Chris H. Martini, M.D., Ph.D.; Suzanne Broens, M.D.; Martijn Boon, M.D.; Marieke Niesters, M.D., Ph.D.; Leon Aarts, M.D., Ph.D.; Erik Olofsen, Ph.D.; Monique van Velzen, Ph.D.; Albert Dahan, M.D., Ph.D.

Anesthesiology May 2019, Vol. 130, 745–755. https://doi.org/10.1097/ALN.0000000000002634

View Articletitled, Nociception-guided versus Standard Care during Remifentanil–Propofol Anesthesia: A Randomized Controlled Trial

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Topics: pain perception , remifentanil , propofol

Relationship between Perioperative Hypotension and Perioperative Cardiovascular Events in Patients with Coronary Artery Disease Undergoing Major Noncardiac Surgery

Pavel S. Roshanov, M.D., M.Sc.; Tej Sheth, M.D.; Emmanuelle Duceppe, M.D.; Vikas Tandon, M.D.; Amal Bessissow, M.D., M.Sc.; Matthew T. V. Chan, M.B.B.S., Ph.D.; Craig Butler, M.Sc., M.D.; Benjamin J. W. Chow, M.D.; James S. Khan, M.Sc., M.D.; P. J. Devereaux, M.D., Ph.D.

Anesthesiology May 2019, Vol. 130, 756–766. https://doi.org/10.1097/ALN.0000000000002654

View Articletitled, Relationship between Perioperative Hypotension and Perioperative Cardiovascular Events in Patients with Coronary Artery Disease Undergoing Major Noncardiac Surgery

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Topics: cardiovascular event , coronary arteriosclerosis , ct angiography of coronary arteries , hypotension , surgical procedures, operative

Critical Care Medicine: Basic Science

Gradually Increasing Tidal Volume May Mitigate Experimental Lung Injury in Rats

Nathane S. Felix, M.D.; Cynthia S. Samary, Ph.D.; Fernanda F. Cruz, M.D., Ph.D.; Nazareth N. Rocha, M.D., Ph.D.; Marcos V. S. Fernandes, M.S.; Joana A. Machado, M.S.; Rebecca L. Bose-Madureira, M.S.; Vera L. Capelozzi, M.D., Ph.D.; Paolo Pelosi, M.D., F.E.R.S.; Pedro L. Silva, Ph.D.; John J. Marini, M.D.; Patricia R. M. Rocco, M.D., Ph.D.

Anesthesiology May 2019, Vol. 130, 767–777. https://doi.org/10.1097/ALN.0000000000002630

View Articletitled, Gradually Increasing Tidal Volume May Mitigate Experimental Lung Injury in Rats

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Topics: extracellular matrix , lung , lung injuries , rats , tidal volume

Extracellular Vesicles from Interferon-γ–primed Human Umbilical Cord Mesenchymal Stromal Cells Reduce Escherichia coli–induced Acute Lung Injury in Rats

Amir K. Varkouhi, M.D., Ph.D.; Mirjana Jerkic, M.D., Ph.D.; Lindsay Ormesher, B.Sc.; Stéphane Gagnon, M.Sc.; Sakshi Goyal, B.Sc.; Razieh Rabani, B.Sc., Ph.D.; Claire Masterson, M.Sc., Ph.D.; Chris Spring, B.Sc.; Paul Z. Chen, B.A.Sc.; Frank X. Gu, Ph.D.; Claudia C. dos Santos, M.D.; Gerard F. Curley, M.B., Ph.D., F.C.A.I.; John G. Laffey, M.D., M.A., F.C.A.I.

Anesthesiology May 2019, Vol. 130, 778–790. https://doi.org/10.1097/ALN.0000000000002655

View Articletitled, Extracellular Vesicles from Interferon-γ–primed Human Umbilical Cord Mesenchymal Stromal Cells Reduce Escherichia coli–induced Acute Lung Injury in Rats

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Topics: extracellular vesicles , mesenchymal stem cells , human leukocyte interferon , interferons

Critical Care Medicine: Clinical Science

Lung Recruitment in Obese Patients with Acute Respiratory Distress Syndrome

Jacopo Fumagalli, M.D.; Roberta R. S. Santiago, M.D., Ph.D.; Maddalena Teggia Droghi, M.D.; Changsheng Zhang, M.D., Ph.D.; Florian J. Fintelmann, M.D.; Fabian M. Troschel, Cand. Med.; Caio C. A. Morais, R.R.T., Ph.D.; Marcelo B. P. Amato, M.D., Ph.D.; Robert M. Kacmarek, R.R.T., Ph.D.; Lorenzo Berra, M.D.; on behalf of the Lung Rescue Team Investigators

Anesthesiology May 2019, Vol. 130, 791–803. https://doi.org/10.1097/ALN.0000000000002638

View Articletitled, Lung Recruitment in Obese Patients with Acute Respiratory Distress Syndrome

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Topics: alveolar recruitment ventilation strategy , obesity , positive end-expiratory pressure , respiratory distress syndrome, adult , lung

Pain Medicine: Basic Science

α2δ-1–Bound N-Methyl-d-aspartate Receptors Mediate Morphine-induced Hyperalgesia and Analgesic Tolerance by Potentiating Glutamatergic Input in Rodents

Meichun Deng, Ph.D.; Shao-Rui Chen, M.D.; Hong Chen, B.S.; Hui-Lin Pan, M.D., Ph.D.

Anesthesiology May 2019, Vol. 130, 804–819. https://doi.org/10.1097/ALN.0000000000002648

View Articletitled, α2δ-1–Bound N-Methyl-d-aspartate Receptors Mediate Morphine-induced Hyperalgesia and Analgesic Tolerance by Potentiating Glutamatergic Input in Rodents

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Topics: analgesics , hyperalgesia , morphine , n-methyl-d-aspartate receptors , spinal cord

Education: Images in Anesthesiology

Inflammation Drives Pulmonary Arterial Hypertension

Neil M. Goldenberg, M.D., Ph.D.; Benjamin E. Steinberg, M.D., Ph.D.

Anesthesiology May 2019, Vol. 130, 820–821. https://doi.org/10.1097/ALN.0000000000002561

View Articletitled, Inflammation Drives Pulmonary Arterial Hypertension

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Topics: inflammation , pulmonary arterial hypertension

Fatal Iatrogenic Pituitary Apoplexy after Surgery for Neuroophthalmological Disorder

Matteo Nioi, M.D.; Pietro Emanuele Napoli, M.D.; Fabio Ferreli, M.D.

Anesthesiology May 2019, Vol. 130, 822. https://doi.org/10.1097/ALN.0000000000002584

View Articletitled, Fatal Iatrogenic Pituitary Apoplexy after Surgery for Neuroophthalmological Disorder

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Topics: pituitary apoplexy , surgery specialty , surgical procedures, operative

Central Venous Pressure Waveform Artifact while Transducing a Single Lumen Port

Joseph A. Cerasuolo, M.D.; Roman Schumann, M.D.

Anesthesiology May 2019, Vol. 130, 823. https://doi.org/10.1097/ALN.0000000000002594

View Articletitled, Central Venous Pressure Waveform Artifact while Transducing a Single Lumen Port

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Topics: artifacts , central venous pressure , waveforms

Sounds Impossible, but It’s Knot

Loren E. Smith, M.D., Ph.D.; Dillon R. Heath, C.R.N.A.; Matthias L. Riess, M.D., Ph.D.

Anesthesiology May 2019, Vol. 130, 824. https://doi.org/10.1097/ALN.0000000000002585

View Articletitled, Sounds Impossible, but It’s Knot

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Topics: academic medical centers , adult , airway device , airway structure , awards and prizes

Education: Clinical Focus Review

Perioperative Fluid Therapy for Major Surgery

Timothy E. Miller, M.B.,Ch.B., F.R.C.A.; Paul S. Myles, M.B., B.S., M.P.H., D.Sc., F.A.N.Z.C.A.

Anesthesiology May 2019, Vol. 130, 825–832. https://doi.org/10.1097/ALN.0000000000002603

View Articletitled, Perioperative Fluid Therapy for Major Surgery

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Topics: fluid management , intravenous fluid , surgical procedures, operative , surgery specialty

Education: Review Article

Preparation for and Management of “Failed” Laryngoscopy and/or Intubation

Richard M. Cooper, M.Sc., M.D.

Anesthesiology May 2019, Vol. 130, 833–849. https://doi.org/10.1097/ALN.0000000000002555

View Articletitled, Preparation for and Management of “Failed” Laryngoscopy and/or Intubation

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Topics: intubation , laryngoscopy , airway device , airway structure , alveolar ventilation function

Education: Mind to Mind

Judas and the Magnetic Resonance
Part of the Letheon Writing Competition

Bill McCabe

Anesthesiology May 2019, Vol. 130, 850. https://doi.org/10.1097/ALN.0000000000002684

View Articletitled, Judas and the Magnetic Resonance

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Topics: vibration

Difficult Social Circumstances

Suzanne Crowe, M.B., F.F.A.R.C.S.I., F.J.F.I.C.M.

Anesthesiology May 2019, Vol. 130, 851–852. https://doi.org/10.1097/ALN.0000000000002592

View Articletitled, Difficult Social Circumstances

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Topics: advocacy , child , infant , intensivist , pediatric intensive care unit

Correspondence

β-Lactam Allergy in the Operating Theater: Comment

Andrew T. Meikle, F.R.C.P.C.; Jennifer Grant, F.R.C.P.C.

Anesthesiology May 2019, Vol. 130, 853–854. https://doi.org/10.1097/ALN.0000000000002688

View Articletitled, β-Lactam Allergy in the Operating Theater: Comment

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β-Lactam Allergy in the Operating Theater: Comment

Leon Vorobeichik, M.D.; Elizabeth A. Weber, M.D., F.R.C.P.C.; Jordan Tarshis, M.D., F.R.C.P.C.

Anesthesiology May 2019, Vol. 130, 854–855. https://doi.org/10.1097/ALN.0000000000002689

View Articletitled, β-Lactam Allergy in the Operating Theater: Comment

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β-Lactam Allergy in the Operating Theater: Reply

Jeroen Hermanides, M.D., Ph.D.; Bregtje A. Lemkes, M.D., Ph.D.; Jan M. Prins, M.D., Ph.D.; Markus W. Hollmann, M.D., Ph.D.; Ingrid Terreehorst, M.D., Ph.D.

Anesthesiology May 2019, Vol. 130, 855–856. https://doi.org/10.1097/ALN.0000000000002690

View Articletitled, β-Lactam Allergy in the Operating Theater: Reply

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Respiratory Muscle Effort during Weaning: Comment

Uğur Özdemir, M.D.; Gül Gürsel, M.D.; Antonio M. Esquinas, M.D., Ph.D., F.C.C.P., A.A.R.C.

Anesthesiology May 2019, Vol. 130, 856–857. https://doi.org/10.1097/ALN.0000000000002696

View Articletitled, Respiratory Muscle Effort during Weaning: Comment

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Respiratory Muscle Effort during Weaning: Reply

Jonne Doorduin, Ph.D.; Leo Heunks, M.D., Ph.D.

Anesthesiology May 2019, Vol. 130, 857. https://doi.org/10.1097/ALN.0000000000002697

View Articletitled, Respiratory Muscle Effort during Weaning: Reply

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Delirium after Cardiac Surgery and Cognitive Change: Comment

Christina Boncyk, M.D.; Christopher G. Hughes, M.D., M.S.

Anesthesiology May 2019, Vol. 130, 857–859. https://doi.org/10.1097/ALN.0000000000002698

View Articletitled, Delirium after Cardiac Surgery and Cognitive Change: Comment

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Delirium after Cardiac Surgery and Cognitive Change: Reply

Charles H. Brown, IV, M.D., M.H.S.; Charles W. Hogue, M.D.

Anesthesiology May 2019, Vol. 130, 859. https://doi.org/10.1097/ALN.0000000000002699

View Articletitled, Delirium after Cardiac Surgery and Cognitive Change: Reply

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Anesthesiology Reflections from the Wood Library-Museum

Renfro Valley Sells a Mountain of Hamlins Wizard Oil: A Chloroform Elixir Cure?

Anesthesiology May 2019, Vol. 130, 673. https://doi.org/10.1097/ALN.0000000000002741

View Articletitled, Renfro Valley Sells a Mountain of Hamlins Wizard Oil: A Chloroform Elixir Cure?

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Not Just Ethyl Chloride or Somnoform: Anestile, a Refrigerant Anesthetic by Bengué

Anesthesiology May 2019, Vol. 130, 676. https://doi.org/10.1097/ALN.0000000000002742

View Articletitled, Not Just Ethyl Chloride or Somnoform: Anestile, a Refrigerant Anesthetic by Bengué

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From Dr. Vernon Harcourt, Chloroform Man, to Dr. Quinn, Medicine Woman: An Anesthetic Anachronism?

Anesthesiology May 2019, Vol. 130, 679. https://doi.org/10.1097/ALN.0000000000002743

View Articletitled, From Dr. Vernon Harcourt, Chloroform Man, to Dr. Quinn, Medicine Woman: An Anesthetic Anachronism?

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Melotte’s Nitrous Oxide Ad…That Subtracted: More Than Vague about That Sprague!

Anesthesiology May 2019, Vol. 130, 755. https://doi.org/10.1097/ALN.0000000000002744

View Articletitled, Melotte’s Nitrous Oxide Ad…That Subtracted: More Than Vague about That Sprague!

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Risky Sleep with Chloral Hydrate: Did Dracula Fail Frankenstein?

Anesthesiology May 2019, Vol. 130, 777. https://doi.org/10.1097/ALN.0000000000002745

View Articletitled, Risky Sleep with Chloral Hydrate: Did Dracula Fail Frankenstein?

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Issues

Cover Image

Table of Contents

Editorial Board

This Month in Anesthesiology

Science, Medicine, and the Anesthesiologist

Infographics in Anesthesiology

Anesthesiology CME Program

Editorial

Special Articles

Perioperative Medicine: Clinical Science

Critical Care Medicine: Basic Science

Critical Care Medicine: Clinical Science

Pain Medicine: Basic Science

Education: Images in Anesthesiology

Education: Clinical Focus Review

Education: Review Article

Education: Mind to Mind

Judas and the Magnetic Resonance Part of the Letheon Writing Competition

Correspondence

Anesthesiology Reflections from the Wood Library-Museum

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Judas and the Magnetic Resonance
Part of the Letheon Writing Competition