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Volume 126, Issue 4

April 2017

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In this Issue

Table of Contents
Editorial Board
This Month in Anesthesiology
Science, Medicine, and the Anesthesiologist
Infographics in Anesthesiology
Anesthesiology CME Program
Editorial
Practice Parameter
Perioperative Medicine: Clinical Science
Perioperative Medicine: Basic Science
Critical Care Medicine: Clinical Science
Pain Medicine: Clinical Science
Pain Medicine: Basic Science
Education: Images in Anesthesiology
Education: Original Investigations in Education
Education: Clinical Concepts and Commentary
Education: Review Article
Education: Mind to Mind
Correspondence
Anesthesiology Reflections from the Wood Library-Museum
Erratum

Anesthesiology

Anesthesiology April 2017, Vol. 126, A13–A16. https://doi.org/10.1097/ALN.0000000000001622

View Articletitled, Anesthesiology

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Editorial Board

Anesthesiology

Anesthesiology April 2017, Vol. 126, A13–A14. https://doi.org/10.1097/ALN.0000000000001591

View Articletitled, Anesthesiology

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This Month in Anesthesiology

This Month in: Anesthesiology

Anesthesiology April 2017, Vol. 126, A1–A2. https://doi.org/10.1097/ALN.0000000000001580

View Articletitled, This Month in: Anesthesiology

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Science, Medicine, and the Anesthesiologist

Anesthesiology April 2017, Vol. 126, A19–A20. https://doi.org/10.1097/ALN.0000000000001575

View Articletitled, Science, Medicine, and the Anesthesiologist

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Infographics in Anesthesiology

Experience Counts: Frailty and Surgical Volume

Jonathan P. Wanderer; James P. Rathmell

Anesthesiology April 2017, Vol. 126, A21. https://doi.org/10.1097/ALN.0000000000001595

View Articletitled, Experience Counts: Frailty and Surgical Volume

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Topics: frailty , surgical procedures, operative

Anesthesiology CME Program

Instructions for Obtaining Anesthesiology Continuing Medical Education (CME) Credit

Anesthesiology April 2017, Vol. 126, A15. https://doi.org/10.1097/ALN.0000000000001592

View Articletitled, Instructions for Obtaining Anesthesiology Continuing Medical Education (CME) Credit

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Editorial

Hospital Experience Caring for the Frail: A New Concern for Surgical Patients

Han Ting Wang, M.D.; Hannah Wunsch, M.D., M.Sc.

Anesthesiology April 2017, Vol. 126, 575–576. https://doi.org/10.1097/ALN.0000000000001537

View Articletitled, Hospital Experience Caring for the Frail: A New Concern for Surgical Patients

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Topics: frail elderly , surgical procedures, operative

Three Wise Men (×2) and the ASA-Physical Status Classification System

BobbieJean Sweitzer, M.D., F.A.C.P.

Anesthesiology April 2017, Vol. 126, 577–578. https://doi.org/10.1097/ALN.0000000000001542

View Articletitled, Three Wise Men (×2) and the ASA-Physical Status Classification System

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Topics: adverse event , comorbidity , health status , intuition , patient-focused outcomes

Anesthetic Neuroprotection? It’s Complicated

David S. Warner, M.D.; Huaxin Sheng, M.D.

Anesthesiology April 2017, Vol. 126, 579–581. https://doi.org/10.1097/ALN.0000000000001535

View Articletitled, Anesthetic Neuroprotection? It’s Complicated

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Topics: neuroprotection

A Road Map to Assess Clinical Competency in Basic Transesophageal Echocardiography

Nikolaos J. Skubas, M.D., F.A.C.C., F.A.S.E., D.Sc.

Anesthesiology April 2017, Vol. 126, 582–584. https://doi.org/10.1097/ALN.0000000000001539

View Articletitled, A Road Map to Assess Clinical Competency in Basic Transesophageal Echocardiography

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Topics: transesophageal echocardiography

Practice Parameter

Practice Advisory for the Prevention, Diagnosis, and Management of Infectious Complications Associated with Neuraxial Techniques: An Updated Report by the American Society of Anesthesiologists Task Force on Infectious Complications Associated with Neuraxial Techniques and the American Society of Regional Anesthesia and Pain Medicine

Anesthesiology April 2017, Vol. 126, 585–601. https://doi.org/10.1097/ALN.0000000000001521

View Articletitled, Practice Advisory for the Prevention, Diagnosis, and Management of Infectious Complications Associated with Neuraxial Techniques: An Updated Report by the American Society of Anesthesiologists Task Force on Infectious Complications Associated with Neuraxial Techniques and the American Society of Regional Anesthesia and Pain Medicine

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Topics: infection as complication of medical care , prevention , advisory committees , consultants

Perioperative Medicine: Clinical Science

Association of the Hospital Volume of Frail Surgical Patients Cared for with Outcomes after Elective, Major Noncardiac Surgery: A Retrospective Population-based Cohort Study

Daniel I. McIsaac, M.D., M.P.H., F.R.C.P.C.; Duminda N. Wijeysundera, M.D., Ph.D., F.R.C.P.C.; Allen Huang, M.D., F.R.C.P.C.; Gregory L. Bryson, M.D., F.R.C.P.C., M.Sc.; Carl van Walraven, M.D., F.R.C.P.C., M.Sc.

Anesthesiology April 2017, Vol. 126, 602–613. https://doi.org/10.1097/ALN.0000000000001536

View Articletitled, Association of the Hospital Volume of Frail Surgical Patients Cared for with Outcomes after Elective, Major Noncardiac Surgery: A Retrospective Population-based Cohort Study

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Topics: frail elderly , frailty , surgical procedures, operative , mortality

Adding Examples to the ASA-Physical Status Classification Improves Correct Assignment to Patients

Erin E. Hurwitz, M.D.; Michelle Simon, M.D.; Sandhya R. Vinta, M.D.; Charles F. Zehm, M.D.; Sarah M. Shabot, M.D.; Abu Minhajuddin, Ph.D.; Amr E. Abouleish, M.D., M.B.A.

Anesthesiology April 2017, Vol. 126, 614–622. https://doi.org/10.1097/ALN.0000000000001541

View Articletitled, Adding Examples to the ASA-Physical Status Classification Improves Correct Assignment to Patients

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Topics: body mass index procedure , comorbidity , hypertension , surgical procedures, operative , blood pressure

Validation and Calibration of the Risk Stratification Index

George F. Chamoun; Linyan Li, M.S.; Nassib G. Chamoun, M.S.; Vikas Saini, M.D.; Daniel I. Sessler, M.D.

Anesthesiology April 2017, Vol. 126, 623–630. https://doi.org/10.1097/ALN.0000000000001560

View Articletitled, Validation and Calibration of the Risk Stratification Index

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Topics: calibration , datasets , mortality , stratification , length of stay

Presepsin (sCD14-ST) Is a Novel Marker for Risk Stratification in Cardiac Surgery Patients

Hagen Bomberg, M.D.; Matthias Klingele, M.D.; Stefan Wagenpfeil, Ph.D.; Eberhard Spanuth, Ph.D.; Thomas Volk, M.D.; Daniel I. Sessler, M.D.; Hans-Joachim Schäfers, M.D.; Heinrich Volker Groesdonk, M.D.

Anesthesiology April 2017, Vol. 126, 631–642. https://doi.org/10.1097/ALN.0000000000001522

View Articletitled, Presepsin (sCD14-ST) Is a Novel Marker for Risk Stratification in Cardiac Surgery Patients

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Topics: cardiac surgery procedures , mortality , preoperative care , stratification , plasma

High-sensitivity Cardiac Troponin Elevation after Electroconvulsive Therapy: A Prospective, Observational Cohort Study

Andreas Duma, M.D., M.Sc.; Swatilika Pal, M.B.B.S., M.S.; Joshua Johnston, D.O.; Mohammad A. Helwani, M.D.; Adithya Bhat, M.D.; Bali Gill, M.D.; Jessica Rosenkvist, M.D.; Christopher Cartmill, B.S.; Frank Brown, B.S.; J. Philip Miller, A.B.; Mitchell G. Scott, Ph.D.; Francisco Sanchez-Conde; Michael Jarvis, M.D., Ph.D.; Nuri B. Farber, M.D.; Charles F. Zorumski, M.D.; Charles Conway, M.D.; Peter Nagele, M.D., M.Sc.

Anesthesiology April 2017, Vol. 126, 643–652. https://doi.org/10.1097/ALN.0000000000001531

View Articletitled, High-sensitivity Cardiac Troponin Elevation after Electroconvulsive Therapy: A Prospective, Observational Cohort Study

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Topics: cardiac troponin measurement , electroconvulsive therapy , cardiac troponin i

Perioperative Medicine: Basic Science

Anesthetic Neuroprotection in Experimental Stroke in Rodents: A Systematic Review and Meta-analysis

David P. Archer, M.D.; Andrew M. Walker, Ph.D.; Sarah K. McCann, Ph.D.; Joanna J. Moser, Ph.D., M.D.; Ramana M. Appireddy, M.B.B.S., D.M.

Anesthesiology April 2017, Vol. 126, 653–665. https://doi.org/10.1097/ALN.0000000000001534

View Articletitled, Anesthetic Neuroprotection in Experimental Stroke in Rodents: A Systematic Review and Meta-analysis

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Topics: ischemic stroke , neuroprotection , rodentia , comorbidity , ischemia

Ketamine Increases the Function of γ-Aminobutyric Acid Type A Receptors in Hippocampal and Cortical Neurons

Dian-Shi Wang, M.D., Ph.D.; Antonello Penna, M.D., Ph.D.; Beverley A. Orser, M.D., Ph.D.

Anesthesiology April 2017, Vol. 126, 666–677. https://doi.org/10.1097/ALN.0000000000001483

View Articletitled, Ketamine Increases the Function of γ-Aminobutyric Acid Type A Receptors in Hippocampal and Cortical Neurons

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Topics: gaba-a receptor , gamma-aminobutyric acid , hippocampus , ketamine , neurons

Critical Care Medicine: Clinical Science

Spontaneous Breathing during Extracorporeal Membrane Oxygenation in Acute Respiratory Failure

Stefania Crotti, M.D.; Nicola Bottino, M.D.; Giulia Maria Ruggeri, M.D.; Elena Spinelli, M.D.; Daniela Tubiolo, M.D.; Alfredo Lissoni, M.D.; Alessandro Protti, M.D.; Luciano Gattinoni, M.D., Ph.D.

Anesthesiology April 2017, Vol. 126, 678–687. https://doi.org/10.1097/ALN.0000000000001546

View Articletitled, Spontaneous Breathing during Extracorporeal Membrane Oxygenation in Acute Respiratory Failure

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Topics: extracorporeal membrane oxygenation , inspiration , respiration , respiratory distress syndrome, adult , lung transplantation

Pain Medicine: Clinical Science

Impact of Pain on Incident Risk of Disability in Elderly Japanese: Cause-specific Analysis

Yu Kaiho, M.D.; Yumi Sugawara, Ph.D.; Kemmyo Sugiyama, M.D.; Yasutake Tomata, Ph.D.; Yasuhiro Endo, M.D., Ph.D.; Hiroaki Toyama, M.D., Ph.D.; Masanori Yamauchi, M.D., Ph.D.; Ichiro Tsuji, M.D., Ph.D.

Anesthesiology April 2017, Vol. 126, 688–696. https://doi.org/10.1097/ALN.0000000000001540

View Articletitled, Impact of Pain on Incident Risk of Disability in Elderly Japanese: Cause-specific Analysis

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Topics: disability , functional disability , older adult , pain , fractures

Respiratory Effects of the Nociceptin/Orphanin FQ Peptide and Opioid Receptor Agonist, Cebranopadol, in Healthy Human Volunteers

Albert Dahan, M.D., Ph.D.; Merel Boom, M.D., Ph.D.; Elise Sarton, M.D., Ph.D.; Justin Hay, Ph.D.; Geert Jan Groeneveld, M.D., Ph.D.; Meike Neukirchen, Ph.D.; John Bothmer, Ph.D.; Leon Aarts, M.D., Ph.D.; Erik Olofsen, M.Sc.

Anesthesiology April 2017, Vol. 126, 697–707. https://doi.org/10.1097/ALN.0000000000001529

View Articletitled, Respiratory Effects of the Nociceptin/Orphanin FQ Peptide and Opioid Receptor Agonist, Cebranopadol, in Healthy Human Volunteers

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Topics: agonists , analgesia (pain absence) , carbon dioxide , nociceptin , opioid receptor

Pain Medicine: Basic Science

Opioid-type Respiratory Depressant Side Effects of Cebranopadol in Rats Are Limited by Its Nociceptin/Orphanin FQ Peptide Receptor Agonist Activity

Klaus Linz, Ph.D.; Wolfgang Schröder, Ph.D.; Stefanie Frosch, Ph.D.; Thomas Christoph, Ph.D.

Anesthesiology April 2017, Vol. 126, 708–715. https://doi.org/10.1097/ALN.0000000000001530

View Articletitled, Opioid-type Respiratory Depressant Side Effects of Cebranopadol in Rats Are Limited by Its Nociceptin/Orphanin FQ Peptide Receptor Agonist Activity

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Topics: agonists , fentanyl , nociceptin , opioid analgesics , opioids

Education: Images in Anesthesiology

Images in Anesthesiology: Examining the Edges of Extravasation

Yuriy S. Bronshteyn, M.D.; Edward A. Bittner, M.D., Ph.D., M.S.Ed.

Anesthesiology April 2017, Vol. 126, 716. https://doi.org/10.1097/ALN.0000000000001487

View Articletitled, Images in Anesthesiology: Examining the Edges of Extravasation

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Topics: extravasation of diagnostic and therapeutic materials

Acquired Bronchoesophageal Fistula and Gastroesophageal Junction Mass

Kenneth N. Hiller, M.D.; Paul G. Loubser, M.D.; Harold S. Minkowitz, M.D.; Mark T. Goldstein, M.D.

Anesthesiology April 2017, Vol. 126, 717. https://doi.org/10.1097/ALN.0000000000001523

View Articletitled, Acquired Bronchoesophageal Fistula and Gastroesophageal Junction Mass

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Topics: esophagogastric junction , pathologic fistula

Education: Original Investigations in Education

Standard Setting for Clinical Performance of Basic Perioperative Transesophageal Echocardiography: Moving beyond the Written Test

Julian S. Bick, M.D.; Jonathan P. Wanderer, M.D., M.Phil.; Conrad S. Myler, M.D.; Andrew D. Shaw, M.B., F.R.C.A., F.F.I.C.M., F.C.C.M.; Matthew D. McEvoy, M.D.

Anesthesiology April 2017, Vol. 126, 718–728. https://doi.org/10.1097/ALN.0000000000001538

View Articletitled, Standard Setting for Clinical Performance of Basic Perioperative Transesophageal Echocardiography: Moving beyond the Written Test

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Topics: transesophageal echocardiography , internship and residency , medical residencies

Education: Clinical Concepts and Commentary

Perioperative Use of Intravenous Lidocaine

Lauren K. Dunn, M.D., Ph.D.; Marcel E. Durieux, M.D., Ph.D.

Anesthesiology April 2017, Vol. 126, 729–737. https://doi.org/10.1097/ALN.0000000000001527

View Articletitled, Perioperative Use of Intravenous Lidocaine

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Topics: infusion procedures , lidocaine , opioids , surgical procedures, operative

Education: Review Article

Cricoid Pressure Controversies: Narrative Review

M. Ramez Salem, M.D.; Arjang Khorasani, M.D.; Ahed Zeidan, M.D.; George J. Crystal, Ph.D.

Anesthesiology April 2017, Vol. 126, 738–752. https://doi.org/10.1097/ALN.0000000000001489

View Articletitled, Cricoid Pressure Controversies: Narrative Review

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Topics: aspirations (psychology) , cricoid cartilage , cricoid pressure , endotracheal aspiration , inspiration

Education: Mind to Mind

Eulogy of the Scions of Jim Crow

Eric Hanson, M.D.

Anesthesiology April 2017, Vol. 126, 753–754. https://doi.org/10.1097/ALN.0000000000001357

View Articletitled, Eulogy of the Scions of Jim Crow

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Topics: agitation , amputation stumps , beds , child , civil rights

Formal Diagnosis

Elizabeth Brooke Baker, M.D.

Anesthesiology April 2017, Vol. 126, 755. https://doi.org/10.1097/ALN.0000000000001364

View Articletitled, Formal Diagnosis

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Topics: dietary sodium chloride , inspiration , listening , milk , respiration

Correspondence

Lung-protective Role of Halogenated Anesthetics: Is It Time to Change This Hypothesis?

Francisco de la Gala, Ph.D.; Ignacio Garutti, Ph.D.; Patricia Piñeiro, Ph.D.; Almudena Reyes, M.D.

Anesthesiology April 2017, Vol. 126, 756. https://doi.org/10.1097/ALN.0000000000001557

View Articletitled, Lung-protective Role of Halogenated Anesthetics: Is It Time to Change This Hypothesis?

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In Reply

Beatrice Beck-Schimmer, M.D.; Milo Puhan, M.D., Ph.D.

Anesthesiology April 2017, Vol. 126, 756–757. https://doi.org/10.1097/ALN.0000000000001559

View Articletitled, In Reply

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Anesthesiology Reflections from the Wood Library-Museum

Conical Relief from Airway Threats: The Chloroform Cone of Trendelenburg

Anesthesiology April 2017, Vol. 126, 584. https://doi.org/10.1097/ALN.0000000000001581

View Articletitled, Conical Relief from Airway Threats: The Chloroform Cone of Trendelenburg

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“Fresh” Laughing Gas or “Wonderful” Odontunder from Dr. Ira W. Stoughton

Anesthesiology April 2017, Vol. 126, 613. https://doi.org/10.1097/ALN.0000000000001582

View Articletitled, “Fresh” Laughing Gas or “Wonderful” Odontunder from Dr. Ira W. Stoughton

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From Basket to Casket? The Basket Bearer of Belladonna for Liebig Company Processing

Anesthesiology April 2017, Vol. 126, 665. https://doi.org/10.1097/ALN.0000000000001583

View Articletitled, From Basket to Casket? The Basket Bearer of Belladonna for Liebig Company Processing

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Ziherl, Kish, and Hingson’s “Portable Anesthesia Machine, Oxygen Inhalator and Resuscitator”

Anesthesiology April 2017, Vol. 126, 677. https://doi.org/10.1097/ALN.0000000000001584

View Articletitled, Ziherl, Kish, and Hingson’s “Portable Anesthesia Machine, Oxygen Inhalator and Resuscitator”

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From Chloroform to Home Rule: Queen Victoria Rides One Wave and Resists Another

Anesthesiology April 2017, Vol. 126, 737. https://doi.org/10.1097/ALN.0000000000001585

View Articletitled, From Chloroform to Home Rule: Queen Victoria Rides One Wave and Resists Another

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Erratum

Vasopressin versus Norepinephrine in Patients with Vasoplegic Shock after Cardiac Surgery: The VANCS Randomized Controlled Trial: Erratum

Anesthesiology April 2017, Vol. 126, 758. https://doi.org/10.1097/ALN.0000000000001543

View Articletitled, Vasopressin versus Norepinephrine in Patients with Vasoplegic Shock after Cardiac Surgery: The VANCS Randomized Controlled Trial: Erratum

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Vasopressin, Norepinephrine, and Vasodilatory Shock after Cardiac Surgery: Another “VASST” Difference? Erratum

Anesthesiology April 2017, Vol. 126, 758. https://doi.org/10.1097/ALN.0000000000001544

View Articletitled, Vasopressin, Norepinephrine, and Vasodilatory Shock after Cardiac Surgery: Another “VASST” Difference? Erratum

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Current Status of Neuromuscular Reversal and Monitoring: Challenges and Opportunities: Erratum

Anesthesiology April 2017, Vol. 126, 758. https://doi.org/10.1097/ALN.0000000000001572

View Articletitled, Current Status of Neuromuscular Reversal and Monitoring: Challenges and Opportunities: Erratum

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Issues

Cover Image

Table of Contents

Editorial Board

This Month in Anesthesiology

Science, Medicine, and the Anesthesiologist

Infographics in Anesthesiology

Anesthesiology CME Program

Editorial

Practice Parameter

Perioperative Medicine: Clinical Science

Perioperative Medicine: Basic Science

Critical Care Medicine: Clinical Science

Pain Medicine: Clinical Science

Pain Medicine: Basic Science

Education: Images in Anesthesiology

Education: Original Investigations in Education

Education: Clinical Concepts and Commentary

Education: Review Article

Education: Mind to Mind

Correspondence

Anesthesiology Reflections from the Wood Library-Museum

Erratum

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