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Volume 122, Issue 3

March 2015

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Cover Image

Cover Image
Table of Contents

In this Issue

Table of Contents
Editorial Board
This Month in Anesthesiology
Science, Medicine, and the Anesthesiologist
Infographics in Anesthesiology
Anesthesiology CME Program
Editorial
Practice Parameter
Special Articles
Perioperative Medicine: Clinical Science
Perioperative Medicine: Basic Science
Critical Care Medicine: Basic Science
Pain Medicine: Clinical Science
Pain Medicine: Basic Science
Education
Education: Review Article
Education: Mind to Mind
Correspondence
Reviews of Educational Material
Anesthesiology Reflections from the Wood Library-Museum
Announcements

Anesthesiology

Anesthesiology March 2015, Vol. 122, A13–A18. https://doi.org/10.1097/01.anes.0000460475.07352.1d

View Articletitled, Anesthesiology

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Editorial Board

Anesthesiology

Anesthesiology March 2015, Vol. 122, A17–A18. https://doi.org/10.1097/01.anes.0000460474.99727.f5

View Articletitled, Anesthesiology

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This Month in Anesthesiology

This Month in: Anesthesiology

Anesthesiology March 2015, Vol. 122, A1–A2. https://doi.org/10.1097/01.anes.0000460472.14976.d4

View Articletitled, This Month in: Anesthesiology

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Science, Medicine, and the Anesthesiologist

Anesthesiology March 2015, Vol. 122, A21–A22. https://doi.org/10.1097/01.anes.0000460476.45470.fb

View Articletitled, Science, Medicine, and the Anesthesiologist

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Infographics in Anesthesiology

Quality of Life: Measuring Disability-free Survival

Jonathan P. Wanderer; James P. Rathmell

Anesthesiology March 2015, Vol. 122, A23. https://doi.org/10.1097/01.anes.0000460477.53093.b9

View Articletitled, Quality of Life: Measuring Disability-free Survival

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Topics: disability , quality of life

Anesthesiology CME Program

Instructions for Obtaining Anesthesiology Continuing Medical Education (CME) Credit

Anesthesiology March 2015, Vol. 122, A19. https://doi.org/10.1097/01.anes.0000460473.22599.90

View Articletitled, Instructions for Obtaining Anesthesiology Continuing Medical Education (CME) Credit

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Editorial

Patient-centered Endpoints for Perioperative Outcomes Research

Cor J. Kalkman, M.D., Ph.D.; Teus H. Kappen, M.D.

Anesthesiology March 2015, Vol. 122, 481–483. https://doi.org/10.1097/ALN.0000000000000587

View Articletitled, Patient-centered Endpoints for Perioperative Outcomes Research

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Topics: outcomes research , patient-centered care , surrogate endpoints

Preventing Respiratory Depression

Daniel I. Sessler, M.D.

Anesthesiology March 2015, Vol. 122, 484–485. https://doi.org/10.1097/ALN.0000000000000565

View Articletitled, Preventing Respiratory Depression

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Topics: respiratory depression

Next Generation of Cardiovascular Studies: Transcriptional Responses of the Human Myocardium during Cardiac Surgery

Michael Koeppen, M.D.; Tobias Eckle, M.D.; Holger K. Eltzschig, M.D.

Anesthesiology March 2015, Vol. 122, 486–488. https://doi.org/10.1097/ALN.0000000000000581

View Articletitled, Next Generation of Cardiovascular Studies: Transcriptional Responses of the Human Myocardium during Cardiac Surgery

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Topics: cardiac surgery procedures , cardiovascular system , myocardium , transcription, genetic

Monumental Efforts: Perspiring Professionals, Conspiring Tradesmen … Inspiring You?

George S. Bause, M.D., M.P.H.

Anesthesiology March 2015, Vol. 122, 489–490. https://doi.org/10.1097/ALN.0000000000000575

View Articletitled, Monumental Efforts: Perspiring Professionals, Conspiring Tradesmen … Inspiring You?

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Topics: legal guardians , museums , nitrous oxide , professors

Finding and Getting What You Want When You Want It Just Got Easier at Anesthesiology

Vicki Tedeschi; James P. Rathmell, M.D.; James C. Eisenach, M.D.

Anesthesiology March 2015, Vol. 122, 491–494. https://doi.org/10.1097/ALN.0000000000000580

View Articletitled, Finding and Getting What You Want When You Want It Just Got Easier at Anesthesiology

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Topics: altmetrics , cell phones , medical devices , podcasts , social media

Practice Parameter

Practice Advisory on Anesthetic Care for Magnetic Resonance Imaging: An Updated Report by the American Society of Anesthesiologists Task Force on Anesthetic Care for Magnetic Resonance Imaging

Anesthesiology March 2015, Vol. 122, 495–520. https://doi.org/10.1097/ALN.0000000000000458

View Articletitled, Practice Advisory on Anesthetic Care for Magnetic Resonance Imaging: An Updated Report by the American Society of Anesthesiologists Task Force on Anesthetic Care for Magnetic Resonance Imaging

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Topics: magnetic resonance imaging , advisory committees

Special Articles

The Monuments Men: In the History of Anesthesia, Too

Luca Borghi, M.A.

Anesthesiology March 2015, Vol. 122, 521–523. https://doi.org/10.1097/ALN.0000000000000576

View Articletitled, The Monuments Men: In the History of Anesthesia, Too

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Topics: army , history of medicine , italy , nitrous oxide , physiology

Perioperative Medicine: Clinical Science

Measurement of Disability-free Survival after Surgery

Mark A. Shulman, M.B., B.S., M.P.H., F.A.N.Z.C.A.; Paul S. Myles, M.B., B.S., M.P.H., M.D., F.A.N.Z.C.A., F.R.C.A.; Matthew T. V. Chan, M.B., B.S., F.A.N.Z.C.A.; David R. McIlroy, M.B., B.S., M.Clin.Epi, F.A.N.Z.C.A.; Sophie Wallace, M.P.H.; Jennie Ponsford, B.A.(Hons), M.A.(Clin Neuropsych), Ph.D.

Anesthesiology March 2015, Vol. 122, 524–536. https://doi.org/10.1097/ALN.0000000000000586

View Articletitled, Measurement of Disability-free Survival after Surgery

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Topics: disability , surgical procedures, operative , world health organization disability assessment schedule , surgery specialty

Using Next-generation RNA Sequencing to Examine Ischemic Changes Induced by Cold Blood Cardioplegia on the Human Left Ventricular Myocardium Transcriptome

Jochen D. Muehlschlegel, M.D., M.M.Sc.; Danos C. Christodoulou, Ph.D.; David McKean, Ph.D.; Joshua Gorham, B.A.; Erica Mazaika, B.S., M.S.; Mahyar Heydarpour, Ph.D.; Grace Lee, M.D.; Steven R. DePalma, Ph.D.; Tjorvi E. Perry, M.D., M.M.Sc.; Amanda A. Fox, M.D., M.P.H.; Stanton K. Shernan, M.D.; Christine E. Seidman, M.D.; Sary F. Aranki, M.D.; Jon G. Seidman, Ph.D.; Simon C. Body, M.B.Ch.B., M.P.H.

Anesthesiology March 2015, Vol. 122, 537–550. https://doi.org/10.1097/ALN.0000000000000582

View Articletitled, Using Next-generation RNA Sequencing to Examine Ischemic Changes Induced by Cold Blood Cardioplegia on the Human Left Ventricular Myocardium Transcriptome

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Topics: cold sensation , cold temperature , common cold , genes , heart arrest, induced

Incidence of Intraoperative Hypersensitivity Reactions: A Registry Analysis: A Registry Analysis

Leif Saager, Dr. Med.; Alparslan Turan, M.D.; Cameron Egan, B.A.; Edward J. Mascha, Ph.D.; Andrea Kurz, M.D.; Maria Bauer, M.D.; Hervé Besson, Ph.D.; Daniel I. Sessler, M.D.; Brian D. Hesler, M.D.

Anesthesiology March 2015, Vol. 122, 551–559. https://doi.org/10.1097/ALN.0000000000000529

View Articletitled, Incidence of Intraoperative Hypersensitivity Reactions: A Registry Analysis: A Registry Analysis

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Topics: hypersensitivity , intraoperative care

Evaluation of a Novel Transfusion Algorithm Employing Point-of-care Coagulation Assays in Cardiac Surgery: A Retrospective Cohort Study with Interrupted Time–Series Analysis

Keyvan Karkouti, M.D.; Stuart A. McCluskey, M.D., Ph.D.; Jeannie Callum, M.D.; John Freedman, M.D.; Rita Selby, M.D.; Tarik Timoumi, M.D.; Debashis Roy, M.D.; Vivek Rao, M.D., Ph.D.

Anesthesiology March 2015, Vol. 122, 560–570. https://doi.org/10.1097/ALN.0000000000000556

View Articletitled, Evaluation of a Novel Transfusion Algorithm Employing Point-of-care Coagulation Assays in Cardiac Surgery: A Retrospective Cohort Study with Interrupted Time–Series Analysis

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Topics: blood coagulation , cardiac surgery procedures , coagulation process , transfusion , interrupted time series analysis

Perioperative Medicine: Basic Science

Intravenous Anesthetic Propofol Inhibits Multiple Human Cardiac Potassium Channels

Lei Yang, M.D.; Hui Liu, M.D., Ph.D.; Hai-Ying Sun, B.Sc.; Gui-Rong Li, Ph.D.

Anesthesiology March 2015, Vol. 122, 571–584. https://doi.org/10.1097/ALN.0000000000000495

View Articletitled, Intravenous Anesthetic Propofol Inhibits Multiple Human Cardiac Potassium Channels

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Topics: atrium , heart , propofol , muscle cells

Fiber-needle Swept-source Optical Coherence Tomography System for the Identification of the Epidural Space in Piglets

Wen-Chuan Kuo, Ph.D.; Meng-Chun Kao, Ph.D. Student; Kuang-Yi Chang, M.D., Ph.D.; Wei-Nung Teng, M.D., Ph.D. Student; Mei-Yung Tsou, M.D., Ph.D.; Yin Chang, Ph.D.; Chien-Kun Ting, M.D., Ph.D.

Anesthesiology March 2015, Vol. 122, 585–594. https://doi.org/10.1097/ALN.0000000000000531

View Articletitled, Fiber-needle Swept-source Optical Coherence Tomography System for the Identification of the Epidural Space in Piglets

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Topics: epidural space , needles , optical coherence tomography , optics

Impaired Autophagosome Clearance Contributes to Local Anesthetic Bupivacaine-induced Myotoxicity in Mouse Myoblasts

Rongrong Li, M.D.; He Ma, M.D.; Xiaojin Zhang, B.S.; Chuanfu Li, M.D.; Jingwei Xiong, M.D.; Ting Lu, M.D.; Yu Mao, B.S.; Juncheng Dai, Ph.D.; Li Liu, M.D., Ph.D.; Zhengnian Ding, M.D., Ph.D.

Anesthesiology March 2015, Vol. 122, 595–605. https://doi.org/10.1097/ALN.0000000000000568

View Articletitled, Impaired Autophagosome Clearance Contributes to Local Anesthetic Bupivacaine-induced Myotoxicity in Mouse Myoblasts

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Topics: autophagosomes , bupivacaine , drug clearance , myotoxicity , therapeutics

Hyperpolarization-activated Cyclic Nucleotide-gated Channels May Contribute to Regional Anesthetic Effects of Lidocaine

Cheng Zhou, Ph.D.; Bowen Ke, Ph.D.; Yi Zhao, M.B.; Peng Liang, M.D.; Daqing Liao, M.B.; Tao Li, Ph.D.; Jin Liu, M.D.; Xiangdong Chen, Ph.D., M.D.

Anesthesiology March 2015, Vol. 122, 606–618. https://doi.org/10.1097/ALN.0000000000000557

View Articletitled, Hyperpolarization-activated Cyclic Nucleotide-gated Channels May Contribute to Regional Anesthetic Effects of Lidocaine

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Topics: lidocaine , mice , nucleotides , ganglia, spinal , neurons

Critical Care Medicine: Basic Science

Dexmedetomidine Attenuates the Microcirculatory Derangements Evoked by Experimental Sepsis

Marcos L. Miranda, M.D., M.Sc.; Michelle M. Balarini, M.D., M.Sc.; Eliete Bouskela, M.D., Ph.D.

Anesthesiology March 2015, Vol. 122, 619–630. https://doi.org/10.1097/ALN.0000000000000491

View Articletitled, Dexmedetomidine Attenuates the Microcirculatory Derangements Evoked by Experimental Sepsis

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Topics: dexmedetomidine , endothelium , leukocytes , lipopolysaccharides , sepsis

Effects of Ultraprotective Ventilation, Extracorporeal Carbon Dioxide Removal, and Spontaneous Breathing on Lung Morphofunction and Inflammation in Experimental Severe Acute Respiratory Distress Syndrome

Andreas Güldner, M.D.; Thomas Kiss, M.D.; Thomas Bluth, M.D.; Christopher Uhlig, M.D.; Anja Braune, M.Sc.; Nadja Carvalho, Ph.D.; Theresa Quast, Cand.Med.; Ines Rentzsch, Ph.D.; Robert Huhle, M.Sc.; Peter Spieth, M.D.; Torsten Richter, M.D.; Felipe Saddy, M.D., Ph.D.; Patricia R. M. Rocco, M.D., Ph.D.; Michael Kasper, Ph.D.; Thea Koch, M.D., Ph.D.; Paolo Pelosi, M.D.; Marcelo Gama de Abreu, M.D., M.Sc., Ph.D., D.E.S.A.

Anesthesiology March 2015, Vol. 122, 631–646. https://doi.org/10.1097/ALN.0000000000000504

View Articletitled, Effects of Ultraprotective Ventilation, Extracorporeal Carbon Dioxide Removal, and Spontaneous Breathing on Lung Morphofunction and Inflammation in Experimental Severe Acute Respiratory Distress Syndrome

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Topics: extracorporeal carbon dioxide removal , inflammation , lung , respiration , respiratory distress syndrome, adult

Computer Control of Drug Delivery by Continuous Intravenous Infusion: Bridging the Gap between Intended and Actual Drug Delivery

Michael J. Parker, M.D.; Mark A. Lovich, M.D., Ph.D.; Amy C. Tsao, B.S.; Abraham E. Wei, B.S.; Matthew G. Wakim, B.S.; Mikhail Y. Maslov, M.D., Ph.D.; Hisashi Tsukada, M.D.; Robert A. Peterfreund, M.D., Ph.D.

Anesthesiology March 2015, Vol. 122, 647–658. https://doi.org/10.1097/ALN.0000000000000519

View Articletitled, Computer Control of Drug Delivery by Continuous Intravenous Infusion: Bridging the Gap between Intended and Actual Drug Delivery

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Topics: computers , drug delivery systems , fluid flow , infusion procedures , steady state

Pain Medicine: Clinical Science

Postoperative Opioid-induced Respiratory Depression: A Closed Claims Analysis

Lorri A. Lee, M.D.; Robert A. Caplan, M.D.; Linda S. Stephens, Ph.D.; Karen L. Posner, Ph.D.; Gregory W. Terman, M.D., Ph.D.; Terri Voepel-Lewis, Ph.D., R.N.; Karen B. Domino, M.D., M.P.H.

Anesthesiology March 2015, Vol. 122, 659–665. https://doi.org/10.1097/ALN.0000000000000564

View Articletitled, Postoperative Opioid-induced Respiratory Depression: A Closed Claims Analysis

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Topics: insurance claim review , opioid analgesics , opioids , respiratory depression , surgical procedures, operative

Role of Spinal CXCL1 (GROα) in Opioid Tolerance: A Human-to-rodent Translational Study

Chih-Peng Lin, M.D.; Kai-Hsiang Kang, Ph.D.; Tzu-Hung Lin, Ph.D.; Ming-Yueh Wu, Ph.D.; Houng-Chi Liou, M.S.; Woei-Jer Chuang, Ph.D.; Wei-Zen Sun, M.D.; Wen-Mei Fu, Ph.D.

Anesthesiology March 2015, Vol. 122, 666–676. https://doi.org/10.1097/ALN.0000000000000523

View Articletitled, Role of Spinal CXCL1 (GROα) in Opioid Tolerance: A Human-to-rodent Translational Study

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Topics: chemokine (c-x-c motif) ligand 1 , morphine , opioid tolerance , cerebrospinal fluid , rodentia

Review of the Performance of Quantitative Sensory Testing Methods to Detect Hyperalgesia in Chronic Pain Patients on Long-term Opioids

Nathaniel P. Katz, M.D.; Florence C. Paillard, Ph.D.; Robert R. Edwards, Ph.D.

Anesthesiology March 2015, Vol. 122, 677–685. https://doi.org/10.1097/ALN.0000000000000530

View Articletitled, Review of the Performance of Quantitative Sensory Testing Methods to Detect Hyperalgesia in Chronic Pain Patients on Long-term Opioids

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Topics: chronic pain , hyperalgesia , opioids , sensory testing

Pain Medicine: Basic Science

GABAergic Inhibition Regulated Pain Sensitization through STEP61 Signaling in Spinal Dorsal Horn of Mice

Lu Li, M.S.; Lei Shi, M.S.; Ying-Ming Xu, M.S.; Xian Yang, M.S.; Zhan-Wei Suo, M.D., Ph.D.; Xiao-Dong Hu, M.D., Ph.D.

Anesthesiology March 2015, Vol. 122, 686–697. https://doi.org/10.1097/ALN.0000000000000532

View Articletitled, GABAergic Inhibition Regulated Pain Sensitization through STEP61 Signaling in Spinal Dorsal Horn of Mice

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Topics: gamma-aminobutyric acid , mice , pain , posterior horn cells , sensitization

Education

Images in Anesthesiology: Facemask Ventilation with a Frontonasal Encephalocele

James Joseph Thomas, M.D.; Christopher Ciarallo, M.D., F.A.A.P.

Anesthesiology March 2015, Vol. 122, 698. https://doi.org/10.1097/ALN.0000000000000312

View Articletitled, Images in Anesthesiology: Facemask Ventilation with a Frontonasal Encephalocele

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Topics: congenital cerebral hernia , environmental air flow , respiration

Education: Review Article

Invasive Treatments for Complex Regional Pain Syndrome in Children and Adolescents: A Scoping Review

Boris Zernikow, M.D., Ph.D.; Julia Wager, Ph.D.; Hannah Brehmer, M.D.; Gerrit Hirschfeld, Ph.D.; Christoph Maier, M.D., Ph.D.

Anesthesiology March 2015, Vol. 122, 699–707. https://doi.org/10.1097/ALN.0000000000000573

View Articletitled, Invasive Treatments for Complex Regional Pain Syndrome in Children and Adolescents: A Scoping Review

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Topics: adolescent , child , complex regional pain syndromes

Education: Mind to Mind

Awareness

Ting Gou, A.B.

Anesthesiology March 2015, Vol. 122, 708–709. https://doi.org/10.1097/ALN.0000000000000533

View Articletitled, Awareness

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Topics: china , cold sensation , cold temperature , common cold , dialects

Sleeping Beauty

Ting Gou, A.B.

Anesthesiology March 2015, Vol. 122, 710–711. https://doi.org/10.1097/ALN.0000000000000534

View Articletitled, Sleeping Beauty

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Topics: beauty , sleep

Ten Things I Learned as an Intern

Walter Crittenden, Pharm.D., M.D.

Anesthesiology March 2015, Vol. 122, 712. https://doi.org/10.1097/ALN.0b013e3182a9afaf

View Articletitled, Ten Things I Learned as an Intern

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Topics: exercise , intern , internship and residency , medical residencies , normal saline

Correspondence

Presence or Absence of Elevated Acute Total Serum Tryptase by Itself Is Not a Definitive Marker for an Allergic Reaction

Juraj Sprung, M.D., Ph.D.; Toby N. Weingarten, M.D.; Lawrence B. Schwartz, M.D., Ph.D.

Anesthesiology March 2015, Vol. 122, 713–714. https://doi.org/10.1097/ALN.0000000000000584

View Articletitled, Presence or Absence of Elevated Acute Total Serum Tryptase by Itself Is Not a Definitive Marker for an Allergic Reaction

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In Reply

Dominique Laroche, M.D., Ph.D.; Philippe Gomis, M.D.; Jean-Marc Malinovsky, M.D., Ph.D.; Paul-Michel Mertes, M.D., Ph.D.

Anesthesiology March 2015, Vol. 122, 714–715. https://doi.org/10.1097/ALN.0000000000000585

View Articletitled, In Reply

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More Attention to Respiration: A Simple but Effective Approach to Reduce Postoperative Mortality?

Gerhard Brodner, M.D., Ph.D.; Hugo Van Aken, M.D., Ph.D.

Anesthesiology March 2015, Vol. 122, 715–716. https://doi.org/10.1097/ALN.0000000000000571

View Articletitled, More Attention to Respiration: A Simple but Effective Approach to Reduce Postoperative Mortality?

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In Reply

Valentín Mazo, M.D.; Sergi Sabaté, M.D., Ph.D.; Jaume Canet, M.D., Ph.D.; Lluís Gallart, M.D., Ph.D.; Marcelo Gama de Abreu, M.D., Ph.D.; Javier Belda, M.D., Ph.D.; Olivier Langeron, M.D., Ph.D.; Andreas Hoeft, M.D., Ph.D.; Paolo Pelosi, M.D.

Anesthesiology March 2015, Vol. 122, 716–717. https://doi.org/10.1097/ALN.0000000000000572

View Articletitled, In Reply

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Reviews of Educational Material

Problem-based Pain Management

Rohit Puranik, M.D.

Anesthesiology March 2015, Vol. 122, 718. https://doi.org/10.1097/ALN.0000000000000544

View Articletitled, Problem-based Pain Management

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Topics: pain management

Comprehensive Atlas of Ultrasound-guided Pain Management Injection Techniques

Alethia Baldwin Sellers, M.D.

Anesthesiology March 2015, Vol. 122, 719. https://doi.org/10.1097/ALN.0000000000000566

View Articletitled, Comprehensive Atlas of Ultrasound-guided Pain Management Injection Techniques

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Topics: pain management , ultrasonography

Anesthesiology Reflections from the Wood Library-Museum

“Rube” Goldberg Asks Is There a Doctor in the House?

Anesthesiology March 2015, Vol. 122, 550. https://doi.org/10.1097/01.anes.0000460478.53093.5d

View Articletitled, “Rube” Goldberg Asks Is There a Doctor in the House?

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McGill’s Gaseous Ambiguity? “Certainly Not!”

Anesthesiology March 2015, Vol. 122, 646. https://doi.org/10.1097/01.anes.0000460479.30223.0c

View Articletitled, McGill’s Gaseous Ambiguity? “Certainly Not!”

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The Pentothal Tubing Bag of Frank L. Faust, M.D.

Anesthesiology March 2015, Vol. 122, 676. https://doi.org/10.1097/01.anes.0000460480.37846.f8

View Articletitled, The Pentothal Tubing Bag of Frank L. Faust, M.D.

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Announcements

2015 Annual Journal Symposium: “The Anesthesiologist and Health Care Redesign”

Anesthesiology March 2015, Vol. 122, 720–722. https://doi.org/10.1097/01.anes.0000460481.75964.85

View Articletitled, 2015 Annual Journal Symposium: “The Anesthesiologist and Health Care Redesign”

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Issues

Cover Image

Table of Contents

Editorial Board

This Month in Anesthesiology

Science, Medicine, and the Anesthesiologist

Infographics in Anesthesiology

Anesthesiology CME Program

Editorial

Practice Parameter

Special Articles

Perioperative Medicine: Clinical Science

Perioperative Medicine: Basic Science

Critical Care Medicine: Basic Science

Pain Medicine: Clinical Science

Pain Medicine: Basic Science

Education

Education: Review Article

Education: Mind to Mind

Correspondence

Reviews of Educational Material

Anesthesiology Reflections from the Wood Library-Museum

Announcements

Email alerts

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