We thank Chamaraux-Tran and Beloeil for their letter and concern about our article.1  Since the lidocaine used in our experiment was water soluble, ethanol was not required as a solvent. Therefore, there was no effect of ethanol in our experiment.

The authors declare no competing interests.

1.
Xing
W
,
Chen
D-T
,
Pan
J-H
,
Chen
Y-H
,
Yan
Y
,
Li
Q
,
Xue
R-F
,
Yuan
Y-F
,
Zeng
W-A
:
Lidocaine induces apoptosis and suppresses tumor growth in human hepatocellular carcinoma cells in vitro and in a xenograft model in vivo.
Anesthesiology
2017
;
126
:
868
81