In the September 2014 letter to the editor, Corso et al.1  commented on preoperative screening for perioperative management of patients with obstructive sleep apnea (OSA) in the recently published Practice Guidelines.2  They stated that, “The STOP-Bang questionnaire has been shown to identify patients at risk with moderate-to-severe OSA, with reasonable certainty and can be easily implemented in the clinical setting.”1  In the reply by Gross et al.,3  the authors indicated that, “While the STOP-Bang scores were shown to correlate with the probability of sleep apnea, it was not established that they correlate with its severity.” This statement is not accurate based on recently published studies supporting a correlation between the STOP-Bang score and the severity of OSA.

In 2012, we demonstrated that as the STOP-Bang score increased, the probability of having more severe OSA also increased. When the score rose from 0 to 2 till 7 to 8, the probability of having moderate-to-severe OSA (apnea-hypopnea index [AHI] > 15 event/h) increased from 18% (95% confidence interval [CI], 13 to 24%) to 60% (95% CI, 44 to 73%). The probability of severe OSA (AHI > 30 event/h) increased from 4% (95% CI, 2 to 8%) to 38% (95% CI, 29 to 53%).4  This indicates that the patients who have a higher score in the STOP-Bang questionnaire would have a greater probability of severe OSA.

In 2011, Farney et al.5  evaluated the STOP-Bang score in patients referred to a sleep clinic and who underwent polysomnography. Although the predominant reason for referral was for suspected OSA, the study population consisted of patients with a variety of conditions, including insomnia, narcolepsy, and behavioral disorders. As the STOP-Bang score increased from 0 to 8, the probability of severe OSA increased from 4.4 to 81.9%. With any score greater than 4, the probability of severe OSA continuously increased with the increase of STOP-Bang score, whereas the probability having non-OSA, mild OSA, or moderate OSA decreased (fig. 1).5  A similar relation between the STOP-Bang score and the severity of OSA was also found in the Chinese patients referred to sleep clinics.6 

Fig. 1.

STOP-Bang score and predicted probability of obstructive sleep apnea in different severity. AHI = apnea-hypopnea index. Adapted, with permission, from the article by Farney et al.5 Adaptations are themselves works protected by copyright. So to publish this adaptation, authorization must be obtained both from the owner of the copyright in the original work and from the owner of copyright in the translation or adaptation.

Fig. 1.

STOP-Bang score and predicted probability of obstructive sleep apnea in different severity. AHI = apnea-hypopnea index. Adapted, with permission, from the article by Farney et al.5 Adaptations are themselves works protected by copyright. So to publish this adaptation, authorization must be obtained both from the owner of the copyright in the original work and from the owner of copyright in the translation or adaptation.

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In summary, the currently available data in the literature support that a correlation exists between a higher STOP-Bang score and the severity of OSA. Accordingly, the STOP-Bang score can be used to not only identify cases with any degree of OSA but also prioritize those who are more likely to have moderate-to-severe disease. To the extent that the severity of sleep apnea characterized by the AHI is useful in clinical management, we would argue that the STOP-Bang questionnaire should be considered the optimal screening tool at the present time and that the score can be used for making more reasoned clinical decisions.

The authors declare no competing interests.

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Corso
RM
,
Gregoretti
C
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Braghiroli
A
,
Fanfulla
F
,
Insalaco
G
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Practice guidelines for the perioperative management of patients with obstructive sleep apnea: Navigating through uncertainty.
Anesthesiology
2014
;
121
:
664
5
2.
Practice guidelines for the perioperative management of patients with obstructive sleep apnea: An updated report by the American Society of Anesthesiologists Task Force on the Perioperative Management of Patients with Obstructive Sleep Apnea.
Anesthesiology
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Gross
JB
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Apfelbaum
JL
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RT
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Nickinovich
DG
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In reply.
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Chung
F
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Subramanyam
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Liao
P
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Sasaki
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Shapiro
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Sun
Y
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High STOP-Bang score indicates a high probability of obstructive sleep apnoea.
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Farney
RJ
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Walker
BS
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Farney
RM
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GL
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JM
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The STOP-Bang equivalent model and prediction of severity of obstructive sleep apnea: Relation to polysomnographic measurements of the apnea/hypopnea index.
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2011
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7
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Luo
J
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Huang
R
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Zhong
X
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Xiao
Y
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Zhou
J
:
Value of STOP-Bang questionnaire in screening patients with obstructive sleep apnea hypopnea syndrome in sleep disordered breathing clinic.
Chin Med J (Engl)
2014
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127
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1843
8